1,680 research outputs found

    Evaluation of Corn Distillers Solubles on Finishing Steer Performance

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    A finishing study was conducted to evaluate the effects of feeding 0, 8, 16, or 20% corn distillers solubles (CDS), as well as the effects of feeding a combination of 16% CDS and 20% wet distillers grains plus solubles (WDGS) to replace a blend of dry-rolled and high-moisture corn on finishing steer performance. As inclusions of CDS increased, ADG linearly increased and F:G linearly decreased. Feeding value of CDS at 20% inclusion was determined to be 147% compared to the corn blend. The addition of WDGS resulted in a decrease in DMI with similar ADG, resulting in a decrease in F:G. Feeding a combination of CDS and WDGS resulted in a feeding value of 161% compared to corn. Feeding CDS up to 20% or in combination with WDGS displaces corn in finishing diets and improves ADG and F:G

    Effects of diet form and feeder adjustment on growth performance of growing-finishing pigs

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    A total of 252 pigs (PIC 327 × 1050, initially 125.2 lb BW) were used in a 69-d trial to determine the effects of diet form and feeder adjustment on growth performance of growing-finishing pigs. Treatments were arranged in a 2 × 3 factorial with the main effects of feeder adjustment and diet form. The 2 feeder adjustments were a narrow feeder adjustment (minimum gap opening of 0.50 in.) and a wide adjustment (minimum gap opening of 1.00 in.). The feeders were adjusted to the minimum gap setting, but the agitation plate could be moved upward to a maximum gap opening of 0.75 or 1.25 in. for the narrow and wide adjustments, respectively. The 3 diet forms were meal, poor-quality pellets (50% pellets and 50% fines), and screened pellets with minimal fines. Average daily gain, ADFI, and F/G were determined by weighing pigs and measuring feed disappearance on d 0, 12, 22, 39, 48, and 69. No diet form × feeder adjustment interactions were observed (P \u3e 0.24). For Phases 1 (d 0 to 22) and 2 (d 22 to 48), feeder adjustment did not influence (P \u3e 0.28) ADG, but ADFI tended to increase (P \u3c 0.07) and F/G worsened (P \u3c 0.05) for pigs fed from the wide adjusted feeders. In Phase 3 (d 48 to 69), no differences were detected in growth performance (P \u3e 0.17) between pigs fed from either feeder adjustment.; Swine Day, Manhattan, KS, November 15, 201

    Effects of source and level of dietary lysine on growth performance of pigs from 24 to 48 lb

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    Three hundred twenty, 24 lb nursery pigs were fed for 19 days to compare the effects of increasing dietary lysine from L-Iysine HCl (L-Lys) or Peptide Plusñ„± (PP) on growth performance. Three dietary treatments (1.025, 1.15, and 1.275% lysine) were each formulated with L-Lys and PP. Negative and positive control corn-soybean meal-based diets were formulated to .90 and 1.275% lysine, respectively. Increasing dietary lysine to 1.275% from L-Lys or PP resulted in increased performance; however, pigs fed the positive control diet had the best overall performance.; Swine Day, Manhattan, KS, November 18, 199

    Loss of Extreme Long-Range Enhancers in Human Neural Crest Drives a Craniofacial Disorder

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    Non-coding mutations at the far end of a large gene desert surrounding the SOX9 gene result in a human craniofacial disorder called Pierre Robin sequence (PRS). Leveraging a human stem cell differentiation model, we identify two clusters of enhancers within the PRS-associated region that regulate SOX9 expression during a restricted window of facial progenitor development at distances up to 1.45 Mb. Enhancers within the 1.45 Mb cluster exhibit highly synergistic activity that is dependent on the Coordinator motif. Using mouse models, we demonstrate that PRS phenotypic specificity arises from the convergence of two mechanisms: confinement of Sox9 dosage perturbation to developing facial structures through context-specific enhancer activity and heightened sensitivity of the lower jaw to Sox9 expression reduction. Overall, we characterize the longest-range human enhancers involved in congenital malformations, directly demonstrate that PRS is an enhanceropathy, and illustrate how small changes in gene expression can lead to morphological variation

    Changes in quality of life, cognition and functional status following catheter ablation of atrial fibrillation

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    Objective To investigate changes in quality of life (QoL), cognition and functional status according to arrhythmia recurrence after atrial fibrillation (AF) ablation. Methods We compared QoL, cognition and functional status in patients with recurrent atrial tachycardia (AT)/AF versus those without recurrent AT/AF in the AXAFA-AFNET 5 clinical trial. We also sought to identify factors associated with improvement in QoL and functional status following AF ablation by overall change scores with and without analysis of covariance (ANCOVA). Results Among 518 patients who underwent AF ablation, 154 (29.7%) experienced recurrent AT/AF at 3 months. Patients with recurrent AT/AF had higher mean CHA(2)DS(2)-VASc scores (2.8 vs 2.3, p Conclusions Patients without recurrent AT/AF appear to experience greater improvement in functional status but similar QoL as those with recurrent AT/AF after AF ablation

    Measurement of the cosmic ray spectrum above 4×10184{\times}10^{18} eV using inclined events detected with the Pierre Auger Observatory

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    A measurement of the cosmic-ray spectrum for energies exceeding 4×10184{\times}10^{18} eV is presented, which is based on the analysis of showers with zenith angles greater than 60∘60^{\circ} detected with the Pierre Auger Observatory between 1 January 2004 and 31 December 2013. The measured spectrum confirms a flux suppression at the highest energies. Above 5.3×10185.3{\times}10^{18} eV, the "ankle", the flux can be described by a power law E−γE^{-\gamma} with index Îł=2.70±0.02 (stat)±0.1 (sys)\gamma=2.70 \pm 0.02 \,\text{(stat)} \pm 0.1\,\text{(sys)} followed by a smooth suppression region. For the energy (EsE_\text{s}) at which the spectral flux has fallen to one-half of its extrapolated value in the absence of suppression, we find Es=(5.12±0.25 (stat)−1.2+1.0 (sys))×1019E_\text{s}=(5.12\pm0.25\,\text{(stat)}^{+1.0}_{-1.2}\,\text{(sys)}){\times}10^{19} eV.Comment: Replaced with published version. Added journal reference and DO
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