25 research outputs found
Agreement and Reliability of Clinician-in-Clinic Versus Patient-at-Home Clinical and Functional Assessments: Implications for Telehealth Services
Ocean acidification alters morphology of all otolith types in Clarkâs anemonefish (Amphiprion clarkii)
Ocean acidification, the ongoing decline of surface ocean pH and [CO 3 2 â ] due to absorption of surplus atmospheric CO2, has far-reaching consequences for marine biota, especially calcifiers. Among these are teleost fishes, which internally calcify otoliths, critical elements of the inner ear and vestibular system. There is evidence in the literature that ocean acidification increases otolith size and alters shape, perhaps impacting otic mechanics and thus sensory perception. Here, larval Clarkâs anemonefish, Amphiprion clarkii (Bennett, 1830), were reared in various seawater pCO2/pH treatments analogous to future ocean scenarios. At the onset of metamorphosis, all otoliths were removed from each individual fish and analyzed for treatment effects on morphometrics including area, perimeter, and circularity; scanning electron microscopy was used to screen for evidence of treatment effects on lateral development, surface roughness, and vaterite replacement. The results corroborate those of other experiments with other taxa that observed otolith growth with elevated pCO2, and provide evidence that lateral development and surface roughness increased as well. Both sagittae exhibited increasing area, perimeter, lateral development, and roughness; left lapilli exhibited increasing area and perimeter while right lapilli exhibited increasing lateral development and roughness; and left asterisci exhibited increasing perimeter, roughness, and ellipticity with increasing pCO2. Right lapilli and left asterisci were only impacted by the most extreme pCO2 treatment, suggesting they are resilient to any conditions short of aragonite undersaturation, while all other impacted otoliths responded to lower concentrations. Finally, fish settlement competency at 10 dph was dramatically reduced, and fish standard length marginally reduced with increasing pCO2. Increasing abnormality and asymmetry of otoliths may impact inner ear function by altering otolith-maculae interactions
Psychiatric and medical comorbidities of eating disorders : findings from a rapid review of the literature
Background: Eating disorders (EDs) are potentially severe, complex, and life-threatening illnesses. The mortality rate
of EDs is signifcantly elevated compared to other psychiatric conditions, primarily due to medical complications and
suicide. The current rapid review aimed to summarise the literature and identify gaps in knowledge relating to any
psychiatric and medical comorbidities of eating disorders.
Methods: This paper forms part of a rapid review) series scoping the evidence base for the feld of EDs, conducted
to inform the Australian National Eating Disorders Research and Translation Strategy 2021â2031, funded and released
by the Australian Government. ScienceDirect, PubMed and Ovid/Medline were searched for English-language studies
focused on the psychiatric and medical comorbidities of EDs, published between 2009 and 2021. High-level evidence
such as meta-analyses, large population studies and Randomised Control Trials were prioritised.
Results: A total of 202 studies were included in this review, with 58% pertaining to psychiatric comorbidities and
42% to medical comorbidities. For EDs in general, the most prevalent psychiatric comorbidities were anxiety (up
to 62%), mood (up to 54%) and substance use and post-traumatic stress disorders (similar comorbidity rates up to
27%). The review also noted associations between specifc EDs and non-suicidal self-injury, personality disorders, and
neurodevelopmental disorders. EDs were complicated by medical comorbidities across the neuroendocrine, skeletal,
nutritional, gastrointestinal, dental, and reproductive systems. Medical comorbidities can precede, occur alongside or
emerge as a complication of the ED.
Conclusions: This review provides a thorough overview of the comorbid psychiatric and medical conditions cooccurring with EDs. High psychiatric and medical comorbidity rates were observed in people with EDs, with comorbidities contributing to increased ED symptom severity, maintenance of some ED behaviours, and poorer functioning
as well as treatment outcomes. Early identifcation and management of psychiatric and medical comorbidities in
people with an ED may improve response to treatment and overall outcomes
Informing the development of Australia's national eating disorders research and translation strategy : a rapid review methodology
Background Eating disorders (EDs) are highly complex mental illnesses associated with significant medical complications. There are currently knowledge gaps in research relating to the epidemiology, aetiology, treatment, burden, and outcomes of eating disorders. To clearly identify and begin addressing the major deficits in the scientific, medical, and clinical understanding of these mental illnesses, the Australian Government Department of Health in 2019 funded the InsideOut Institute (IOI) to develop the Australian Eating Disorder Research and Translation Strategy, the primary aim of which was to identify priorities and targets for building research capacity and outputs. A series of rapid reviews (RR) were conducted to map the current state of knowledge, identify evidence gaps, and inform development of the national research strategy. Published peer-reviewed literature on DSM-5 listed EDs, across eight knowledge domains was reviewed: (1) population, prevalence, disease burden, Quality of Life in Western developed countries; (2) risk factors; (3) co-occurring conditions and medical complications; (4) screening and diagnosis; (5) prevention and early intervention; (6) psychotherapies and relapse prevention; (7) models of care; (8) pharmacotherapies, alternative and adjunctive therapies; and (9) outcomes (including mortality). While RRs are systematic in nature, they are distinct from systematic reviews in their aim to gather evidence in a timely manner to support decision-making on urgent or high-priority health concerns at the national level. Results Three medical science databases were searched as the primary source of literature for the RRs: Science Direct, PubMed and OVID (Medline). The search was completed on 31st May 2021 (spanning January 2009-May 2021). At writing, a total of 1,320 articles met eligibility criteria and were included in the final review. Conclusions For each RR, the evidence has been organised to review the knowledge area and identify gaps for further research and investment. The series of RRs (published separately within the current series) are designed to support the development of research and translation practice in the field of EDs. They highlight areas for investment and investigation, and provide researchers, service planners and providers, and research funders rapid access to quality current evidence, which has been synthesised and organised to assist decision-making
Self-Compassion, emotion regulation and stress among australian psychologists: Testing an emotion regulation model of self-compassion using structural equation modeling
Psychologists tend to report high levels of occupational stress, with serious implications for themselves, their clients, and the discipline as a whole. Recent research suggests that selfcompassion is a promising construct for psychologists in terms of its ability to promote psychological wellbeing and resilience to stress; however, the potential benefits of self-compassion are yet to be thoroughly explored amongst this occupational group. Additionally, while a growing body of research supports self-compassion as a key predictor of psychopathology, understanding of the processes by which self-compassion exerts effects on mental health outcomes is limited. Structural equation modelling (SEM) was used to test an emotion regulation model of self-compassion and stress among psychologists, including postgraduate trainees undertaking clinical work (n = 198). Self-compassion significantly negatively predicted emotion regulation difficulties and stress symptoms. Support was also found for our preliminary explanatory model of self-compassion, which demonstrates the mediating role of emotion regulation difficulties in the self-compassion-stress relationship. The final self-compassion model accounted for 26.2% of variance in stress symptoms. Implications of the findings and limitations of the study are discussed
Environmental influences on reproductive health: the importance of chemical exposures
Chemical exposures during pregnancy can have a profound and life-long impact on human health. Due to the omnipresence of chemicals in our daily life, there is continuous contact with chemicals in food, water, air and consumer products. Consequently, human biomonitoring studies show that pregnant women around the globe are exposed to a variety of chemicals. In this review, we provide a summary of current data on maternal and fetal exposure as well as health consequences from these exposures. We review several chemical classes including polychlorinated biphenyls (PCBs), perfluoroalkyl substances (PFAS), polybrominated diphenyl ethers (PBDEs), phenols, phthalates, pesticides, and metals. Additionally, we discuss environmental disparities and vulnerable populations, and future research directions. We conclude by providing some recommendations for prevention of chemical exposure and its adverse reproductive health consequences
The development and implementation of a model of online, facilitated, peer group supervision developed to increase accessibility to clinical supervision for dietitians working in eating disorders
In 2018 the Queensland Eating Disorder Services (QuEDS) piloted a novel online, facilitated peer group supervision model. The aim of the QuEDS Facilitated Group Supervision Pilot program was to increase service capacity to deliver acceptable, accessible, low-cost peer group support to Queensland-based dietitians providing dietetic interventions to patients with eating disorders and increase their clinical knowledge and confidence.
Here, we provide a detailed description of the post pilot implementation of the QuEDSâ Facilitated Group Supervision model to encourage replicability and comparison with other models. The evaluation manuscript is currently under review and will be linked here when published
Geochemical evolution of the Dras-Kohistan Arc during collision with Eurasia: Evidence from the Ladakh Himalaya, India
The Dras 1 Volcanic Formation of the Ladakh Himalaya, India, represents the eastern, upper crustal equivalent of the lower crustal gabbros and mantle peridotites of the Kohistan Arc exposed in Pakistan. Together these form a Cretaceous intraoceanic arc now located within the Indus Suture zone between India and Eurasia. During the Late Cretaceous, the Dras-Kohistan Arc, which was located above a north-dipping subduction zone, collided with the south-facing active margin of Eurasia, resulting in a switch from oceanic to continental arc volcanism. In the present study we analyzed samples from the pre-collisional Dras 1 Volcanic Formation and the postcollisional Kardung Volcanic Formation for a suite of trace elements and Nd isotopes. The Kardung Volcanic Formation shows more pronounced light rare earth element enrichment, higher Th/La and lower ΔNd values compared with the Dras 1 Volcanic Formation. These differences are consistent with an increase in the reworking of the continental crust by sediment subduction through the arc after collision. As little as 20% of the Nd in the Dras 1 Volcanic Formation might be provided by sources such as the Karakoram, while approximately 45% of the Nd in the Kardung Volcanic Formation is from this source. However, even before collision, the Dras- Kohistan Arc shows geochemical evidence for more continental sediment contamination than is seen in modern western Pacific arcs, implying its relative proximity to the Eurasian landmass. Comparison of the lava chemistry in the Dras-Kohistan Arc with that in the forearc turbidites suggests that these sediments are partially postcollisional, Jurutze Formation and not all pre-collisional Nindam Formation. Thus, the Dras-Eurasia collision can be dated as Turonian-Santonian (83.5-93.5 Ma), older than it was previously considered to be, but consistent with radiometric ages from Kohistan
Trace element and Pb isotopic constraints on the provenance of the Rosroe and Derryveeny formations, South Mayo, Ireland
The Rosroe Formation comprises a series of Lower Ordovician (Llanvirn) conglomerates and sandstones, that lies on the southern limb of the South Mayo Trough, within the Iapetus Suture Zone of western Ireland. Trace element chemistry of granite boulders within the formation indicates a continental, rather than a volcanic arc character that can be correlated to latest Precambrian granites within the Dalradian Metamorphic Block, part of the deformed Laurentian margin. A minority of the clasts may correlate with syn-collisional granites, similar to, but older than, the Oughterard Granite of Connemara. Pb isotope compositions of K-feldspar grains within the sandstones, measured by both ion microprobe and conventional mass spectrometry, show a clear Laurentian affinity, albeit with greater source variability in the sand grains compared to a limited range in the proximal boulders. Palaeo-current indicators demonstrate dominant derivation from the NE, with a significant axial E-W flow. We propose that the Rosroe Formation records unroofing of a rapidly exhuming Dalradian metamorphic belt in North Mayo, following extensional collapse of the Grampian Orogen starting at âŒ468 Ma, with minor input from a southerly are source. The lack of metamorphic input from the S until deposition of the Derryeeny Conglomerate argues that the Connemara terrane was not positioned S of South Mayo Trough through strike-slip faulting until after the end of Rosroe sedimentation (460-443 Ma)
A model for continental crust genesis by arc accretion: Rare earth element evidence from the Irish Caledonides
The formation of continental crust is a complex problem with a paradox at its center: continental material is believed to form by arc magmatism, a model that does not reconcile the bulk mafic and light rare earth element (LREE)-depleted composition of intra-oceanic arcs with the andesitic, LREE-enriched composition of continents. We present evidence supporting an arc origin for continental crust by demonstrating significant changes in magmatic chemistry during arc continent collision. We use as an example the Connemara region of the western Irish Caledonides, where metamorphism and orogenesis of Dalradian sedimentary sequences record the collision of the oceanic Lough Nafooey Arc with the passive margin of Laurentia at ⌠475 Ma (Arenig). This arc was mafic and LREE-depleted during its oceanic activity. During collision, rhyolites more LREE-enriched than the surrounding continental crust were erupted, while the mid-crust was intruded by similarly LREE-enriched gabbro and diorite. Crystal fractionation caused LREE enrichment to exceed that expected by assimilation of continental crust alone. We propose that subsequent loss of the corresponding lower crustal cumulates into the mantle removed this LREE-depleted material from the net crust added to the continent. The combined processes of crystal fractionation and lower crustal loss during arc continent collision drive the average bulk arc composition toward that of average continental crust. © 2002 Elsevier Science B.V. All rights reserved