Measuring the Score Matching of the Pairwise Deoxyribonucleic Acid Sequencing using Neuro-Fuzzy

The proposed model for getting the score matching of the deoxyribonucleic acid (DNA) sequence is introduced; the Neuro-Fuzzy procedure is the strategy actualized in this paper; it is used the collection of biological information of the DNA sequence performing with global and local calculations so as to advance the ideal arrangement; we utilize the pairwise DNA sequence alignment to gauge the score of the likeness, which depend on information gathering from the pairwise DNA series to be embedded into the implicit framework; an adaptive neuro-fuzzy inference system model is reasonable for foreseeing the matching score through the preparation and testing in neural system and the induction fuzzy system in fuzzy logic that accomplishes the outcome in elite execution

The Mechanism of Monitoring and Tracking of Healthcare Systems

This work concerned with e-healthcare that transmit digital medical data through healthcare system. Online monitoring is concentrated on the process of monitoring and tracking of people at home, car, office, and any other location. e-healthcare deals with patients that they are located far from doctor jurisdiction. Healthcare monitoring including measurements of temperature, blood pressure / pulse monitors and ECG, etc. This works deals with the development of monitoring system via adding intelligent system to distinguish the emergency cases. This work try to keep patient data privacy, reduce attack or penetration of data, reduce processing time and at the same time increasing the efficiency of the overall system. The privacy of patient data is critical so this must maintain the confidentiality of information from intrusion

The effect of CT angiography and venous couplers on surgery duration in microvascular breast reconstruction: a single operator’s experience

Background: The use of CT angiography (CTA) or venous couplers (VCs) has led to shorter operative times in free flap breast reconstruction (FFBR). However, there are no reports on the effect of these two interventions relative to each other or combined. Methods: Abdominal based FFBRs performed by a single surgeon before introduction of either intervention were compared to those with VC only, and those after the addition of CTA to VCs (CT-VC). Operative time was defined as from “knife-to-skin” to insertion of the last stitch. Results: One hundred and twenty patients; 40 without intervention (WI), 40 with VC, and 40 with CT-VC. Introduction of VCs did not significantly reduce operative time compared to WI (P=0.73). However, patients in the CT-VC group had significantly shorter operations vs. WI (472 vs. 586 min, P<0.00001) and vs. VC alone (472 vs. 572 min, P=0.0006). Similarly, introduction of each intervention showed a stepwise decrease in ischaemia time (WI vs. VC: 100 vs. 89 min, P=0.0106; VC vs. CT-VC: 89 vs. 80 min, P=0.0307; WI vs. CT-VC: 100 vs. 80 min, P<0.00001). Conclusions: Combination of CTA and VC significantly reduced operative and ischaemic times for FFBR; this was predominantly due to use of CTA. CTA mitigates the surgical learning curve as demonstrated by shorter operating times via providing a vascular anatomy roadmap, thus facilitating flap harvest

The Efficiency of Wastewater Treatment Plants for the Removal of Antibiotics

Undoubtedly domestic Wastewater Treatment Plants (WWTPs) are not designed for the removal of some pollutants such as antibiotics. This chapter summarizes the occurrence and fate of six groups of the most widely used antibiotics (β-lactams, sulfonamides, quinolones, tetracyclines, macrolides, and others) in domestic WWTPs. The literature showed that the six groups of antibiotics have been frequently detected during wastewater treatment train (influent, primary treatment, secondary treatment, tertiary treatment, effluent, and sludge treatment) of domestic WWTPs. Also, it was clear that the main removal routes of antibiotics during sewage treatment of domestic WWTPs were adsorption, biodegradation, membrane filtration, and disinfection. Domestic WWTPs cannot remove most of the antibiotics which finally enter the environment through treated effluent and sludge

Solving vehicle routing problem by using improved K-nearest neighbor algorithm for best solution

Vehicle routing problem (VRP) is one of the many difficult issues that have no perfect solutions yet. Many researchers over the last few decades have established numerous researches and used many methods with different techniques to handle it. But, for all research, finding the lowest cost is very complex. However, they have managed to come up with approximate solutions that differ in efficiencies depending on the search space. Problem: In this study the problem is as follows: have a number of vehicles which are used for transporting applications to instance place. Each vehicle starts from a main location at different times every day. The vehicle picks up applications from start locations to the instance place in many different routes and return back to the start location in at specific times every day, starting from early morning until the end of official working hours, on the following conditions: (1) Every location will be visited once in each route, and (2) The capacity of each vehicle is enough for all applications included in each route. Objectives: Our paper attempt to find an optimal route result for VRP by using K-Nearest Neighbor Algorithm (KNNA). To achieve an optimal solution for VRP with the accompanying targets: (1) To reduce the distance and the time for all paths this leads to speedy the transportation of customers to their locations, (2) To implement the capacitated vehicle routing problem (CVRP) model for optimizing the solutions. Approach: The approach has been presented based on two phases: firstly, the algorithms have been adapted to solve the research problem, where its procedure is different than the common algorithm. The structure of the algorithm is designed so that the program does not require a large database to store the population, which speeds up the implementation of the program execution to obtain the solution; secondly, the algorithm has proven its success in solving the problem and finds a shortest route. For the purpose of testing the algorithm’s capability and reliability, it was applied to solve the same problem online validated and it achieved success in finding a shorter route. Finding: The findings outcome from this study have shown that: (1) A universal listed of dynamic KNNACVRP; (2) Identified and built up an assessment measure for KNNACVRP; (3) Highlight the strategies, based KNNA operations, for choosing the most ideal way (4) KNNA finds a shorter route for VRP paths. The extent of lessening the distance for each route is generally short, but the savings in the distance becomes more noteworthy while figuring the aggregate distances traveled by all transports day by day or month to month. This applies likewise to the time calculate that has been decreased marginally in view of the rate of reduction in the distances of the paths

Implications of abnormal abdominal wall computed tomographic angiography findings on postmastectomy free flap breast reconstruction.

BACKGROUND: Preoperative computed tomography angiography (CTA) of the abdominal wall vessels is used when planning free flap breast reconstruction (FFBR) because it provides a surgical road map which facilitates flap harvest. However, there are few reports on the effect of abnormal findings on the operative plan. METHODS: We conducted a retrospective study of all FFBRs performed at a tertiary referral center over a 6-year period (November 2011 to June 2017). One consultant radiologist reported on the findings. Details on patient demographics, CTA reports, and intraoperative details were collected. RESULTS: Two hundred patients received preoperative CTAs. Fourteen percent of patients (n=28) had abnormal findings. Of these findings, 18% were vascular anomalies; 36% tumorrelated and 46% were "miscellaneous." In four patients, findings subsequently prevented surgery; they comprised a mesenteric artery aneurysm, absent deep inferior epigastric (DIE) vessels, bilateral occluded DIE arteries, and significant bone metastases. Another patient had no suitable vessels for a free flap and the surgical plan converted to a pedicled transverse rectus abdominis musculocutaneous flap. The remaining incidental findings had no impact on the surgical plan or appropriateness of FFBR. More than one in 10 of those with abnormal findings went on to have further imaging before their operation. CONCLUSIONS: CTA in FFBR can have a wider impact than facilitating surgical planning and reducing operative times. Incidental findings can influence the surgical plan, and in some instances, avoid doomed-to-fail and unsafe surgery. It is therefore important that these scans are reported by an experienced radiologist

Climate Impact Storylines for Assessing Socio-Economic Responses to Remote Events

Complex interactions involving climatic features, socio-economic vulnerability or responses, and long impact transmissions are associated with substantial uncertainty. Physical climate storylines are proposed as approach to explore complex impact transmission pathways and possible alternative unfolding of event cascades under future climate conditions. These storylines are particularly useful for climate risk assessment for complex domains, including event cascades crossing multiple disciplinary or geographical borders. For an effective role in climate risks assessments, practical guidelines are needed to consistently develop and interpret the storyline event analyses.This paper elaborates on the suitability of physical climate storyline approaches involving climate event induced shocks propagating into societal impacts. It proposes a set of common elements to construct the event storylines. In addition, criteria for their application for climate risk assessment are given, referring to the need for storylines to be physically plausible, relevant for the specific context, and risk-informative.Six examples of varying scope and complexity are presented, all involving the potential climate change impact on European socio-economic sectors induced by remote climate change features occurring far outside the geographical domain of the European mainland. The storyline examples illustrate the application of the proposed storyline components and evaluates the suitability criteria defined in this paper. It thereby contributes to the standardization of the design and application of event-based climate storyline approaches

The 2022 drought needs to be a turning point for European drought risk management

The 2022 European drought has underscored critical deficiencies in European water management. This paper explores these shortcomings and suggests a way forward for European drought risk management. Data for this study was gathered through a continent-wide survey of water managers involved in this event. The survey collected 481 responses from 30 European countries and is comprised of 19 questions concerning sectorial impact in the 55 regions of the responders and drought risk management practices of their organizations. Information from the survey is enriched with climate-related information to offer a comprehensive overview of drought risk management in Europe. Our research focuses on four key aspects: the increasing risk of drought, its spatial and temporal impacts, current drought risk management approaches, and the evolution of drought risk management across the continent. Our findings reveal a consensus on the growing risk of drought, which is confounded by the rising frequency and intensity of droughts. While the 2022 event affected most of the continent, our findings show significant regional disparities in drought risk management capacity among the various countries. Our analysis indicates that current drought risk management measures often rely on short-term operational concerns, particularly in agriculture-dominated economies, leading to potentially maladaptive practices. An overall positive trend in drought risk management, with organizations showing increased awareness and preparedness, indicates how this crisis can be the ideal moment to mainstream European-wide drought risk management. Consequently, we advocate for a European Drought Directive, to harmonize and enforce drought risk management policies across the continent. This directive should promote a systemic, integrated, and long-term risk management perspective. The directive should also set clear guidelines for drought risk management at the national level and for cross-boundary drought collaboration. This study and its companion paper "The 2022 Drought Shows the Importance of Preparedness in European Drought Risk Management " are the result of a study carried out by the Drought in the Anthropocene (DitA) network