How Do You Rate As a Roommate?

Before you came to college, you made up your mind that living with a roommate was going to be wonderful. You knew you wouldn\u27t be content living alone. You\u27d get fed up talking to yourself and talking back to a radio soon loses its charm. The only answer, of course, was a roommate. The college sent you her name and you probably spent hours composing a witty, friendly letter to her. But now, after seveeral weeks of living together, you\u27re not so sure that the next nine months will be as swell as you\u27d hoped. You two just don\u27t seem to get along together

Experience Proves Money Planning Can Be Fun

What? You\u27re having dollars and dimes trouble already? Don\u27t write Dad for more money. Make the most of what you have. At the beginning of the school year, you are constantly called upon to spend more money. You have membership dues to pay, books and supplies are required and it is a temptation to spend hours and dimes in the Union. After the first few weeks, however, you suddenly stop and wonder where all of your money has disappeared to

The Iowa Homemaker vol.28, no.7

Third Finger, Left Hand, Jo Ann Breckenridge, page 3 Better Listening on WOI-FM, Walt Miller, page 4 Cook’s Favorite at Chi Omega, Mary Alice Halverson, page 5 What’s New, Peggy Krenek, page 6 Vicky, Jo Ann Breckenridge, page 7 Basketball From the Bleachers, Jules Gerard, page 8 Consumers Speak, Janet Sutherland, page 10 Summer Jobs, Elinor Chase, page 14 Keeping Up, Mary West, page 1

The Iowa Homemaker vol.28, no.3

Memo to a Freshman, page 2 Money Planning Can Be Fun, Mary Alice Halverson, page 3 If Marriage Is in Your Future, Jo Ann Breckenridge, page 4 There’s Excitement Ahead, Katherine Williams, page 6 Activities Point Up Fun for Free Time, Margaret Edgar, page 7 Faculty Suggests Electives, Peggy Ann Krenek, page 8 All You Have To Do Is Eat, Janet Sutherland, page 9 Meet Your Counselors, Elinor Chase, page 10 Vicky, Jo Ann Breckenridge, page 12 What’s New, Peggy Ann Krenek, page 17 Testing Bureau, Barbara Allen, page 19 Keeping Up With Today, Mary West, page 2

No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer

Objective. Clinical genetic testing is commercially available for rs61764370, an inherited variant residing in a KRAS 3' UTR microRNA binding site, based on suggested associations with increased ovarian and breast cancer risk as well as with survival time. However, prior studies, emphasizing particular subgroups, were relatively small. Therefore, we comprehensively evaluated ovarian and breast cancer risks as well as clinical outcome associated with rs61764370. Methods. Centralized genotyping and analysis were performed for 140,012 women enrolled in the Ovarian Cancer Association Consortium (15,357 ovarian cancer patients; 30,816 controls), the Breast Cancer Association Consortium (33,530 breast cancer patients; 37,640 controls), and the Consortium of Modifiers of BRCA1 and BRCA2 (14,765 BRCA1 and 7904 BRCA2 mutation carriers). Results. We found no association with risk of ovarian cancer (OR = 0.99, 95% CI 0.94-1.04, p = 0.74) or breast cancer (OR = 0.98, 95% CI 0.94-1.01, p = 0.19) and results were consistent among mutation carriers (BRCA1, ovarian cancer HR = 1.09, 95% CI 0.97-1.23, p = 0.14, breast cancer HR = 1.04, 95% CI 0.97-1.12, p = 0.27; BRCA2, ovarian cancer HR = 0.89, 95% CI 0.71-1.13, p = 034, breast cancer HR = 1.06, 95% CI 0.94-1.19, p = 0.35). Null results were also obtained for associations with overall survival following ovarian cancer (HR = 0.94, 95% CI 0.83-1.07, p = 0.38), breast cancer (HR = 0.96, 95% CI 0.87-1.06, p = 0.38), and all other previously-reported associations. Conclusions. rs61764370 is not associated with risk of ovarian or breast cancer nor with clinical outcome for patients with these cancers. Therefore, genotyping this variant has no clinical utility related to the prediction or management of these cancers. (C) 2015 Elsevier Inc. All rights reserved.Peer reviewe