SISTEM INFORMASI PELAJARAN PADA SMP YPK MERAUKE

SMP YPK Merauke adalah salah satu Lembaga Pendidikan sekolah di Kota Merauke yang sama seperti sekolah pada lainnya bertujuan untuk mengubah tingkah laku individu menuju arah yang lebih baik melalui interaksi dengan lingkungan sekitar melalui proses belajar mengajar dan dengan kondisi situasi pandemic Covid-19 proses belajar mengajar harus mengikuti protocol kesehatan yang sebelumnya waktu belajar hingga 6 jam dalam sehari atau lebih sekarang berkurang menjadi 3 jam dalam sehari serta pertemuan waktu belajar di sekolah yang sebelumnya 6 hari dalam seminggu menjadi 2 hari dalam seminggu membuat guru dan pihak sekolah mengalami kesulitan dalam proses belajar mengajar sehingga murid banyak ketinggalan materi pelajaran yang ada. Dan Informasi tugas sekolah yang terlambat diinfokan membuat murid terlambat mengerjakan dan mengumpulkan tugas. oleh sebab, itu penelitian ini bertujuan untuk dapat membantu guru dalam memberikan materi pelajaran secara online kepada murid. Metode pengumpulan data yang digunakan berupa wawancara kepada guru atau staf serta murid pada SMP YPK Merauke, setelah data terkumpul berupa data guru, data murid, maka data mata pelajaran maka dimulai pembuatan sistem. Sistem dibuat menggunakan Android studio dan untuk manajemen database menggunakan Firebase. Setelah sistem selesai dibuat maka dilakukan pengujian terhadap sistem, pengujian yang digunakan adalah metode Black-Box untuk menguji fungsi dari sistem apakah sudah sesuai dengan rancangan yang dibuat dan pengujian metode UAT (User Acceptance Testing) untuk menguji sistem apakah sudah berjalan sesuai fungsinya berdasarkan kebutuhan guru dan murid. Mengacu pada hasil pengujian sistem menggunakan Black-Box, didapatkan bahwa sistem yang dibuat dapat memfasilitasi guru dalam memberikan materi, tugas kepada murid secara online serta membantu murid dalam mengakses materi pelajaran dan tugas secara online. Berdasarkan hasil tersebut dalam pengujian UAT (User Acceptance Testing) didapatkan hasil bahwa 80% guru menyatakan sistem dapat memfasilitasi untuk memberikan materi dan tugas secara online, serta 80% murid menyatakan sistem sangat memfasilitasi dalam mengakses materi pelajaran dan tugas secara online

Poleward range expansion without a southern contraction in the ground beetle Agonum viridicupreum (Coleoptera, Carabidae)

Drees C, Brandmayr P, Buse J, et al. Poleward range expansion without a southern contraction in the ground beetle Agonum viridicupreum (Coleoptera, Carabidae). ZooKeys. 2011;100(100):133-352.We investigated the extent of poleward shifts in the distribution range of Agonum viridicupreum due to climate change in the western Palaearctic. Species’ records were obtained from extensive literature sources as well as from collections, and consistent amateur entomologists’ recordings. Within the general geographic range of the species, we analyzed in detail two parts of both, the northern and southern distribution range boundaries: (1 and 2) north-western Germany (leading or high-latitude edge), (3) Israel and (4) southern Italy (rear or low-latitude edge). Temporal changes in the occurrence data of the species indicated a northward shift of the leading edge of a minimum of 100 km within the last 50 to 100 years. In contrast, according to the data gathered, the rear edge has not changed during the last decades. Further studies are needed in order to fully understand the underlying mechanisms of the different behaviour of leading and rear range edges of A. viridicupreum in the current context of global change. Despite our incomplete understanding, chronosequences of the occurrence of the given species have the potential to optimize climate niche modelling to predict trends in the distribution range in the future

Cell mediated immune response in human antirabies revaccination

The occurrence of secondary cell mediated immune response (CMI) in human antirabies immunization was studied. The Puenzalida & Palácios vaccine was used because it is routinely used in Brazil. CMI was evaluated by lymphoblastic transformation indices obtained in whole blood culture in the presence of rabies and control (nervous tissue) antigens. Eleven volunteers submitted to revaccination constituted the group under study, while three other volunteers submitted primo vaccination were utilized as control group. A clear secondary CMI to rabies antigen was detected in all the revaccinated volunteers who showed earlier and more intense response than the control group. Response to the control antigen, however, present in all the components of the first group was not detectable in two out of the three primovaccinated and very low in the third one

Antibody response in cattle after vaccination with inactivated and attenuated rabies vaccines Resposta imune humoral anti-rábica em bovinos imunizados com vacina inativada e atenuada

Despite the absence of current official reports showing the number of cattle infected by rabies, it is estimated that nearly 30,000 bovines are lost each year in Brazil. In order to minimize the important economic losses, control of the disease is achieved by eliminating bat colonies and by herd vaccination. In this study, we compare the antibody response in cattle elicited by vaccination with an attenuated ERA vaccine (AEvac) and an inactivated-adjuvanted PV (IPVvac) vaccine. The antibody titers were appraised by cell-culture neutralization test and ELISA, and the percentage of seropositivity was ascertained for a period of 180 days. IPVvac elicited complete seropositivity rates from day 30 to day 150, and even on day 180, 87% of the sera showed virus-neutralizing antibody titers (VNA) higher than 0.5IU/ml. There were no significant differences between the VNA titers and seropositivity rates obtained with IPVvac in the two methods tested. AEvac, however, elicited significantly lower titers than those observed in the group receiving inactivated vaccine. In addition, the profiles of antirabies IgG antibodies, evaluated by ELISA, and VNA, appraised by cell-culture neutralization test, were slightly different, when both vaccines were compared.<br>A raiva bovina, transmitida principalmente pelo morcego hematófago Desmodus rotundus, é endêmica em várias regiões do Brasil, com um crescente número de casos sendo registrados anualmente. O controle desta infecção em bovinos é feito pelo controle de colônias de morcegos hematófagos e pela vacinação dos rebanhos. Embora as vacinas inativadas sejam mais seguras e mais estáveis que as vacinas atenuadas, estas últimas são ainda amplamente utilizadas em muitas regiões do país, por se acreditar que confiram imunidade mais duradoura. Neste estudo, foram comparadas as respostas anticórpicas de dois grupos de bovinos imunizados com uma vacina atenuada e uma inativada disponíveis comercialmente. Os anticorpos anti-rábicos neutralizantes (AcN) foram titulados pela técnica de soroneutralização em cultura de células BHK-21, enquanto que os níveis de anticorpos anti-rábicos totais (IgG) foram avaliados pela técnica de ELISA, por um período de 180 dias. A vacina inativada induziu a soroconversão (AcN 3 0,5 UI/ml) em 100% dos animais no dia 30, mantendo-se assim até o 150o dia; no dia 180, 87% dos animais ainda mostravam-se com títulos de AcN 3 0,5 UI/ml. Neste grupo, os níveis de IgG anti-rábicas foram semelhantes aos de AcN. A vacina atenuada, no entanto, induziu títulos de AcN e de IgG significantemente menores que os encontrados com a vacina inativada, com consequente diminuição da taxa de soropositividade. Além disso, ao contrário do verificado com a vacina inativada, o perfil de AcN não teve paralelismo com o de anticorpos IgG quando soros foram testados pela técnica de soroneutralização e pelo ELISA, respectivamente