1,357 research outputs found

    Deformation monitoring of a super-tall structure using real-time strain data

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    2013-2014 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptPublishe

    An iterative substructuring approach to the calculation of eigensolution and eigensensitivity

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    Author name used in this manuscript: You-Lin Xu2010-2011 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptPublishe

    Substructure based approach to finite element model updating

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    Author name used in this manuscript: You-Lin Xu2010-2011 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptPublishe

    Improved substructuring method for eigensolutions of large-scale structures

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    Author name used in this manuscript: You-Lin Xu2008-2009 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptPublishe

    Substructuring approach to the calculation of higher-order eigensensitivity

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    2012-2013 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptPublishe

    Inverse substructure method for model updating of structures

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    2011-2012 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptPublishe

    Variation of structural vibration characteristics versus non-uniform temperature distribution

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    Author name used in this manuscript: You-Lin Xu2010-2011 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptPublishe

    Construction of stiffness and flexibility for substructure-based model updating

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    2013-2014 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

    Synthesis and biodegradation of St-g-poly(MMA-co-VAc) initiated by manganic pyrophosphate

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    Methyl methacrylate(MMA) and vinyl acetate(VAc) were grafted onto corn starch with manganic pyrophosphate {[Mn (H2P2O7)(3)](3-)} as the initiator and water as the reaction medium. The influences of reaction conditions, including pH value, initiator concentration, monomer concentration and its composition, on percent grafting and grafting efficiency were investigated. The graft copolymer was characterized by means of IR spectroscopy, scanning electron micrograph(SEM) and H-1 NMR spectroscopy. The biodegradation experiment showed that the degradation of corn starch-g-poly(MMA-co-VAc) was mainly from starch. However, after poly VAc in the side chain was transformed into poly vinyl alcohol(PVA), both starch and the grafted side chain could be degraded completely

    Pan-cancer analysis of the extent and consequences of intratumor heterogeneity

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    Intratumor heterogeneity (ITH) drives neoplastic progression and therapeutic resistance. We used the bioinformatics tools ‘expanding ploidy and allele frequency on nested subpopulations’ (EXPANDS) and PyClone to detect clones that are present at a >= 10% frequency in 1,165 exome sequences from tumors in The Cancer Genome Atlas. 86% of tumors across 12 cancer types had at least two clones. ITH in the morphology of nuclei was associated with genetic ITH (Spearman’s correlation coefficient, rho = 0.24-0.41; P 2 clones coexisted in the same tumor sample (HR = 1.49, 95% CI: 1.20-1.87). In two independent data sets, copy-number alterations affecting either 75% of a tumor’s genome predicted reduced risk (HR = 0.15, 95% CI: 0.08-0.29). Mortality risk also declined when > 4 clones coexisted in the sample, suggesting a trade-off between the costs and benefits of genomic instability. ITH and genomic instability thus have the potential to be useful measures that can universally be applied to all cancers
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