Spectator detection for the measurement of proton neutron interactions at ANKE

A telescope of three silicon detectors has been installed close to the internal target position of the ANKE spectrometer, which is situated inside the ultra-high vacuum of the COSY-Juelich light-ion storage ring. The detection and identification of slow protons and deuterons emerging from a deuterium cluster-jet target thus becomes feasible. A good measurement of the energy and angle of such a spectator proton (p_sp) allows one to identify a reaction as having taken place on the neutron in the target and then to determine the kinematical variables of the ion-neutron system on an event-by-event basis over a range of c.m. energies. The system has been successfully tested under laboratory conditions. By measuring the spectator proton in the p d to p_sp d pi^0 reaction in coincidence with a fast deuteron in the ANKE Forward Detector, values of the p n to d pi^0 total cross-section have been deduced. Further applications of the telescope include the determination of the luminosity and beam polarisation which are required for several experiments.Comment: 16 pages, 9 figure

Medium effects in the production and pi0 gamma decay of omega-mesons in pA collisions in the GeV region

The omega-resonance production and its pi0 gamma decay in p-A reactions close to threshold is considered within the Intranuclear Cascade (INC) Model. The pi0 gamma invariant mass distribution shows two components which correspond to the omega decay 'inside' and 'outside' the nucleus, respectively. The 'inside' component is distorted by medium effects, which introduce a mass shift as well as collisional broadening for the omega-meson and its decaying pion. The relative contribution of the 'inside' component is analyzed in detail for different kinematical conditions and nuclear targets. It is demonstrated that a measurement of the correlation in azimuthal angle between the pi0 and gamma momenta allows to separate events related to the 'inside' omega decay from different sources of background when uncorrelated pi0's and gamma's are produced.Comment: 24 pages, 11 figure

Near threshold eta meson production in the d+d->alpha+eta reaction

The d+d->alpha+eta reaction has been investigated near threshold using the ANKE facility at COSY-Juelich. Both total and differential cross sections have been measured at two excess energies, Q=2.6 MeV and 7.7 MeV, with a subthreshold measurement being undertaken at Q=-2.6 MeV to study the physical background. While consistent with isotropy at the lower energy, the angular distribution reveals a pronounced anisotropy at the higher one, indicating the presence of higher partial waves. Options for the decomposition into partial amplitudes and their consequences for determination of the s-wave eta-alpha scattering length are discussed.Comment: 8pp, fig.3 added, normalisation in eq.4.1 correcte

Autocrine and Paracrine Secretion of Vascular Endothelial Growth Factor in the Pre-Hypoxic Diabetic Retina

Vascular endothelial growth factor (VEGF) is well established as the main agent responsible for vascular leakage and angiogenesis in the diabetic retina. While VEGF can have positive effects on hyperglycemia stressed retinal tissues, it also plays a role in events progressing to the oxygen- stressed, i.e. hypoxic, diabetic retina. Some VEGF makes its way to the retina from systemic sources and some is produced locally within the eye. Hyperglycemia, oxidants, inflammation, and advanced glycation end-products are all stimulants to VEGF production, both in the hypoxic and the pre-hypoxic retina. Endothelial cells, pericytes, Müller cells, microglia, astrocytes, retinal pigment epithelium and neurons have all been known to produce VEGF at some point in retinal development or in disease. Excessive VEGF production in the early diabetic retina can lead to retinal exposure or mechanisms which exacerbate further damage. While Müller cells are likely the most significant producer of VEGF in the pre-hypoxic retina, other VEGF producing cells may also play a role due to their proximity to vessels or neurons. Study of the release of VEGF by retinal cells in hyperglycemia conditions, may help identify targets for early treatment and prevent the serious consequences of diabetic retinopathy

Kaon pair production in proton-nucleus collisions at 2.83 GeV kinetic energy

The production of non-phi K+K- pairs by protons of 2.83 GeV kinetic energy on C, Cu, Ag, and Au targets has been investigated using the COSY-ANKE magnetic spectrometer. The K- momentum dependence of the differential cross section has been measured at small angles over the 0.2--0.9 GeV/c range. The comparison of the data with detailed model calculations indicates an attractive K- -nucleus potential of about -60 MeV at normal nuclear matter density at a mean momentum of 0.5 GeV/c. However, this approach has difficulty in reproducing the smallness of the observed cross sections at low K- momenta.Comment: 7 pages, 5 figures, 1 tabl

Structure, bonding and morphology of hydrothermally synthesised xonotlite

The authors have systematically investigated the role of synthesis conditions upon the structure and morphology of xonotlite. Starting with a mechanochemically prepared, semicrystalline phase with Ca/Si=1, the authors have prepared a series of xonotlite samples hydrothermally, at temperatures between 200 and 250 degrees C. Analysis in each case was by X-ray photoelectron spectroscopy, environmental scanning electron microscopy and X-ray diffraction. The authors’ use of a much lower water/solid ratio has indirectly confirmed the ‘through solution’ mechanism of xonotlite formation, where silicate dissolution is a key precursor of xonotlite formation. Concerning the role of temperature, too low a temperature (~200 degrees C) fails to yield xonotlite or leads to increased number of structural defects in the silicate chains of xonotlite and too high a temperature (>250 degrees C) leads to degradation of the xonotlite structure, through leaching of interchain calcium. Synthesis duration meanwhile leads to increased silicate polymerisation due to diminishing of the defects in the silicate chains and more perfect crystal morphologies

Evidence of kaon nuclear and Coulomb potential effects on soft K+ production from nuclei

The ratio of forward K+ production on copper, silver and gold targets to that on carbon has been measured at proton beam energies between 1.5 and 2.3 GeV as a function of the kaon momentum p_K using the ANKE spectrometer at COSY-Juelich. The strong suppression in the ratios observed for p_K<200-250 MeV/c can be ascribed to a combination of Coulomb and nuclear repulsion in the K+A system. This opens a new way to investigate the interaction of K+-mesons in the nuclear medium. Our data are consistent with a K+A nuclear potential of V_K~20 MeV at low kaon momenta and normal nuclear density. Given the sensitivity of the data to the kaon potential, the current experimental precision might allow one to determine V_K to better than 3 MeV.Comment: 9 pages, 3 figures; changed conten

Kaon Pair Production in Proton--Proton Collisions

The differential and total cross sections for kaon pair production in the pp->ppK+K- reaction have been measured at three beam energies of 2.65, 2.70, and 2.83 GeV using the ANKE magnetic spectrometer at the COSY-Juelich accelerator. These near-threshold data are separated into pairs arising from the decay of the phi-meson and the remainder. For the non-phi selection, the ratio of the differential cross sections in terms of the K-p and K+p invariant masses is strongly peaked towards low masses. This effect can be described quantitatively by using a simple ansatz for the K-p final state interaction, where it is seen that the data are sensitive to the magnitude of an effective K-p scattering length. When allowance is made for a small number of phi events where the K- rescatters from the proton, the phi region is equally well described at all three energies. A very similar phenomenon is discovered in the ratio of the cross sections as functions of the K-pp and K+pp invariant masses and the identical final state interaction model is also very successful here. The world data on the energy dependence of the non-phi total cross section is also reproduced, except possibly for the results closest to threshold.Comment: 12 two-column pages, 12 figures, 1 tabl

Photoproduction of eta-mesic 3He

The photoproduction of eta-mesic 3He has been investigated using the TAPS calorimeter at the Mainz Microtron accelerator facility MAMI. The total inclusive cross section for the reaction gamma+3He->eta+X has been measured for photon energies from threshold to 820 MeV. The total and angular differential coherent eta cross sections have been extracted up to energies of 745 MeV. A resonance-like structure just above the eta production threshold with an isotropic angular distribution suggests the existence of a resonant quasi-bound state. This is supported by studies of a competing decay channel of such a quasi-bound eta-mesic nucleus into pi^0+p+X. A binding energy of (-4.4+-4.2) MeV and a width of (25.6+-6.1) MeV is deduced for the quasi-bound eta-mesic state in 3He.Comment: v1: 4 pages, 4 figures, submitted to PRL; v2: minor revisions and corrections, new figure added, 4 pages, 5 figs; v3: minor change

The Near-Threshold Production of Phi Mesons in pp Collisions

The pp->pp phi reaction has been studied at the Cooler Synchrotron COSY-Juelich, using the internal beam and ANKE facility. Total cross sections have been determined at three excess energies epsilon near the production threshold. The differential cross section closest to threshold at epsilon=18.5 MeV exhibits a clear S-wave dominance as well as a noticeable effect due to the proton-proton final state interaction. Taken together with data for pp omega-production, a significant enhancement of the phi/omega ratio of a factor 8 is found compared to predictions based on the Okubo-Zweig-Iizuka rule.Comment: 4 Pages, 3 Figures, 1 Table, submitted to Phys. Rev. Let