PENGEMBANGAN SISTEM APLIKASI LOKASI RUMAH KOST KABUPATEN PRINGSEWU BERBASIS WEB MOBILE

Boarding house today is a promising business, this is because more and more people need a place to live. But in determining the location of boarding house is very difficult so that the need for an application system to solve the problem. This is what makes the author wants to design an application system location of boarding house Pringsewu District. Number of choice of location of boarding house in Pritsewu District then made an application that serves to determine the location of the right board for easier and faster. This system is a system that can help the community in determining the location of the boarding house as desired. With this application is expected to help the community in finding the location of suitable boarding house, especially in Pringsewu District. The method used in making this application is the method of observation

Structural, magnetic, and transport properties of Co nanoparticles within a Cu matrix

We have studied the structural, magnetic, and transport properties of Co nanoparticles embedded in a Cu matrix using x-ray absorption fine structure (XAFS) spectroscopy, macroscopic magnetization, and transport measurements. We observed by XAFS, on annealed samples containing 3, 10, 12, and 25 at. % Co, that there is a systematic contraction of the average coordination distance around Co atoms with the increasing Co content and annealing. The results are consistent with the growing of small fcc nanoparticles and correlated to the evolution in the superparamagnetic behavior, observed by magnetization measurements. We present a simple model to connect the diameter of Co nanoparticles to the average coordination distance and its mean-square fluctuation. Our analysis leads to cluster sizes ranging from 1 nm to more than 8 nm. We found that for a particle diameter of about 4.4 nm the sample containing 10 at. % Co presents a maximum in the giant magnetoresistance (GMR). Moreover, we observed that the disorder is significantly reduced around that size, due to the hardening of Co bonds, further favoring the GMR. Our analysis gives direct structural parameters and emphasizes their role in the transport and magnetic properties of the Co-Cu system.68

Local anisotropy in strained manganite thin films

We report on an angular resolved x-ray absorption spectroscopy study of the local atomic structure around the manganese ions in La0.7Sr0.3MnO3 thin films epitaxially grown on tensile and compressive substrates. Ab initio calculations provide strong support to the analysis of the experimental data and make possible the unambiguous derivation of a model of local distortion around the manganese atoms, without modification of the tilt angle Mn-O-Mn, among the octahedra. This distortion, tending to localize the charge carriers, is the driving parameter in the modifications of the magnetic and transport properties observed in thin films with respect to bulk systems. (C) 2003 American Institute of Physics.83173587358

A co-culture nanofibre scaffold model of neural cell degeneration in relevance to Parkinson’s disease

Current therapeutic strategies for Parkinson’s disease (PD) aim to delay progression or replace damaged neurons by restoring the original neuronal structures. The poor regenerative capacity of neural tissue highlights the need for the development of cellular environments to model the pathogenesis of PD. In the current work, we have characterised the growth, survival and response to PD mimetics of human SH-SY5Y neuroblastoma and U-87MG glioblastoma cell lines cultured on polyacrylonitrile (PAN) and Jeffamine® doped polyacrylonitrile (PJ) nano-scaffolds. Differentiation induced by a range of agents was evaluated by immunoassays of neural protein biomarkers. PAN and PJ nanofibre scaffolds provided suitable three-dimensional (3D) environment to support the growth, differentiation and network formation of dopaminergic neuron- and astrocyte-like cell populations, respectively. The scaffolds selectively supported the survival and differentiation of both cell populations with prolonged neuronal survival when exposed to PD mimetics in the presence of astrocytes in a co-culture model. Such 3D nanoscaffold-based assays could aid our understanding of the molecular basis of PD mimetic-induced Parkinsonism and the discovery of neuroprotective agents

Multiplex ligation-dependent probe amplification versus karyotyping in prenatal diagnosis: the M.A.K.E. study

Abstract BACKGROUND: In the past 30 years karyotyping was the gold standard for prenatal diagnosis of chromosomal aberrations in the fetus. Traditional karyotyping (TKT) has a high accuracy and reliability. However, it is labor intensive, the results take 14-21 days, the costs are high and unwanted findings such as abnormalities with unknown clinical relevance are not uncommon. These disadvantages challenged the practice of karyotyping. Multiplex ligation-dependent probe amplification (MLPA) is a new molecular genetic technique in prenatal diagnosis. Previous preclinical evidence suggests equivalence of MLPA and traditional karyotyping (TKT) regarding test performance. METHODS/DESIGN: The proposed study is a multicentre diagnostic substitute study among pregnant women, who choose to have amniocentesis for the indication advanced maternal age and/or increased risk following prenatal screening test. In all subjects, both MLPA and karyotyping will be performed on the amniotic fluid sample. The primary outcome is diagnostic accuracy. Secondary outcomes will be maternal quality of life, women's preferences and costs. Analysis will be intention to treat and per protocol analysis. Quality of life analysis will be carried out within the study population. The study aims to include 4500 women. DISCUSSION: The study results are expected to help decide whether MLPA can replace traditional karyotyping for 'low-risk' pregnancies in terms of diagnostic accuracy, quality of life and women's preferences. This will be the first clinical study to report on all relevant aspects of the potential replacement