National and Regional Estimates of the Prevalence of Opiate and/or Crack Cocaine use 2008-09: A summary of key findings

<p>This report summarises the results of a follow-up study to a three year project to estimate the prevalence of ‘problem drug use’ (defined as use of opiates and/or crack cocaine) nationally (England only), regionally and locally. The follow-up was carried out two years after the final sweep of the original project, so could therefore be considered as ‘sweep 5’. An overview of the national and regional estimates are presented in this report, as are comparisons with the estimates produced by the third (2006-07) sweep of the study. Estimates for 2007-08 are not available as a study was not commissioned for that year.</p> <p>Information about the number of people who use illicit drugs such as heroin, other opiates or crack cocaine is key to formulating effective policies for tackling drug-related harm as these drugs are associated with the highest levels of harm. It also helps inform service provision at the local level and provides a context in which to understand the population impact of interventions to reduce drug-related harm.</p> <p>Direct enumeration of those engaged in a largely covert activity such as the use of class A drugs is difficult and standard household survey techniques tend to underestimate the extent of such activity. Indirect techniques making use of various data sources offer a more reliable way of calculating prevalence estimates for the use of opiates and/or crack cocaine. The estimates presented in this report are derived using two indirect measurement techniques: the capture-recapture method (CRC ); and the multiple indicator (MIM ) method. These methods are described in detail in Hay et al., 2006 and Hay et al., 2007a. Methodological developments throughout the course of the previous three sweeps are discussed elsewhere (Hay et al., 2007b, Hay et al., 2008). The individuals covered by this study were people aged 15 to 64 and resident in each DAT area, and known to be using heroin, methadone, other opiate drugs or crack cocaine.</p&gt

Anti-Trust and Economic Theory: Some Observations from the US Experience

Recent developments in US anti-trust can be characterised as reflecting the uneasy interaction of two quite separate phenomena: first, the increased emphasis on economic analysis as the overriding organising principle of anti-trust policy and on economic efficiency as the primary (perhaps only) relevant goal for anti-trust; second, the long-standing reluctance of the federal judiciary to involve itself in any substantive economic analysis, and the preference, instead, for simple rules of thumb or ‘pigeon holes’ to sort out lawful from unlawful conduct. The result has been that while economics has played a major role, it has not influenced American anti-trust as thoroughly or as uniformly as might have been imagined; rather the extent and the nature of its influence have depended on the degree to which the relevant economics could be reduced to the kind of simple rules or pigeon holes that the judiciary favours. The present paper will illustrate that theme, first by reporting on the two developments separately and then by illustrating their joint influence with reference to two important areas of American anti-trust: predatory conduct and so-called vertical restraints. Finally, a contrast will be made between judicial development in those two areas and recent American merger policy which, it is argued, is carried out largely independently of the judiciary, and hence the opportunities for economics to influence the process are less inhibited by the judicial reluctance to undertake extensive economic analysis

Charge identification for spectral lines in nitrogen

Ion charge identification for spectral lines in nitrogen by beam foil light source techniqu

Uncertainties in land use data

This paper deals with the description and assessment of uncertainties in land use data derived from Remote Sensing observations, in the context of hydrological studies. Land use is a categorical regionalised variable reporting the main socio-economic role each location has, where the role is inferred from the pattern of occupation of land. The properties of this pattern that are relevant to hydrological processes have to be known with some accuracy in order to obtain reliable results; hence, uncertainty in land use data may lead to uncertainty in model predictions. There are two main uncertainties surrounding land use data, positional and categorical. The first one is briefly addressed and the second one is explored in more depth, including the factors that influence it. We (1) argue that the conventional method used to assess categorical uncertainty, the confusion matrix, is insufficient to propagate uncertainty through distributed hydrologic models; (2) report some alternative methods to tackle this and other insufficiencies; (3) stress the role of metadata as a more reliable means to assess the degree of distrust with which these data should be used; and (4) suggest some practical recommendations

Tissue eosinophilia and eosinophil degranulation in Riedel's invasive fibrous thyroiditis.

The etiology of Riedel's invasive fibrous thyroiditis (IFT) has remained obscure. This rare disorder has been confused in the past with the more common fibrous variant of Hashimoto's disease. The typical histological features of IFT, in particular the presence of an invasive fibrosclerotic process in conjunction with a prominent chronic inflammatory infiltrate, suggest that the release of fibrogenic cytokines and other factors from these cellular infiltrates may play an important role in the pathogenesis of this condition. Our observations in routinely processed tissue sections obtained from patients with documented IFT of striking tissue eosinophilia led us to hypothesize that eosinophils and their products may play a role in the evolution of this disease. Immunofluorescence staining with affinity-purified polyclonal rabbit antibody directed against human eosinophil granule major basic protein revealed marked tissue eosinophilia and abundant extracellular deposition of major basic protein in all specimens from 16 patients with IFT. By contrast, only occasional eosinophils and no extracellular major basic protein were detected in control thyroid tissues obtained from patients with multinodular goiter, Graves' disease, Hashimoto's disease, and normal thyroid tissue. The presence of marked eosinophil infiltration and extracellular major basic protein deposition in IFT and other associated fibrosclerotic conditions suggests a role for eosinophils and their products in propagating the fibrogenesis seen in IFT

Blind spots in IPE : marginalized perspectives and neglected trends in contemporary capitalism

Which blind spots shape scholarship in International Political Economy (IPE)? That question animates the contributions to a double special issue—one in the Review of International Political Economy, and a companion one in New Political Economy. The global financial crisis had seemed to vindicate broad-ranging IPE perspectives at the expense of narrow economics theories. Yet the tumultuous decade since then has confronted IPE scholars with rapidly-shifting global dynamics, many of which had remained underappreciated. We use the Blind Spots moniker in an attempt to push the topics covered here higher up the scholarly agenda—issues that range from institutionalized racism and misogyny to the rise of big tech, intensifying corporate power, expertise-dynamics in global governance, assetization, and climate change. Gendered and racial inequalities as blind spots have a particular charge. There has been a self-reinforcing correspondence between topics that have counted as important, people to whom they matter personally, and the latter’s ability to build careers on them. In that sense, our mission is not only to highlight collective blind spots that may dull IPE’s capacity to theorize the current moment. It is also a normative one—a form of disciplinary housekeeping to help correct both intellectual and professional entrenched biases

Measured Sensitivity of the First Mark II Phased Array Feed on an ASKAP Antenna

This paper presents the measured sensitivity of CSIRO's first Mk. II phased array feed (PAF) on an ASKAP antenna. The Mk. II achieves a minimum system-temperature-over-efficiency $T_\mathrm{sys}/\eta$ of 78 K at 1.23 GHz and is 95 K or better from 835 MHz to 1.8 GHz. This PAF was designed for the Australian SKA Pathfinder telescope to demonstrate fast astronomical surveys with a wide field of view for the Square Kilometre Array (SKA).Comment: 5 pages, 2 figures, accepted for publication in Electromagnetics in Advanced applications (ICEAA), 2015 International Conference o

Regional agriculture surveys using ERTS-1 data

The Center for Remote Sensing Research has conducted studies designed to evaluate the potential application of ERTS data in performing agricultural inventories, and to develop efficient methods of data handling and analysis useful in the operational context for performing large area surveys. This work has resulted in the development of an integrated system utilizing both human and computer analysis of ground, aerial, and space imagery, which has been shown to be very efficient for regional crop acreage inventories. The technique involves: (1) the delineation of ERTS images into relatively homogeneous strata by human interpreters, (2) the point-by-point classification of the area within each strata on the basis of crop type using a human/machine interactive digital image processing system; and (3) a multistage sampling procedure for the collection of supporting aerial and ground data used in the adjustment and verification of the classification results