863 research outputs found
Finite Element Simulation of Dense Wire Packings
A finite element program is presented to simulate the process of packing and
coiling elastic wires in two- and three-dimensional confining cavities. The
wire is represented by third order beam elements and embedded into a
corotational formulation to capture the geometric nonlinearity resulting from
large rotations and deformations. The hyperbolic equations of motion are
integrated in time using two different integration methods from the Newmark
family: an implicit iterative Newton-Raphson line search solver, and an
explicit predictor-corrector scheme, both with adaptive time stepping. These
two approaches reveal fundamentally different suitability for the problem of
strongly self-interacting bodies found in densely packed cavities. Generalizing
the spherical confinement symmetry investigated in recent studies, the packing
of a wire in hard ellipsoidal cavities is simulated in the frictionless elastic
limit. Evidence is given that packings in oblate spheroids and scalene
ellipsoids are energetically preferred to spheres.Comment: 17 pages, 7 figures, 1 tabl
Comparisons of Supergranule Characteristics During the Solar Minima of Cycles 22/23 and 23/24
Supergranulation is a component of solar convection that manifests itself on
the photosphere as a cellular network of around 35 Mm across, with a turnover
lifetime of 1-2 days. It is strongly linked to the structure of the magnetic
field. The horizontal, divergent flows within supergranule cells carry local
field lines to the cell boundaries, while the rotational properties of
supergranule upflows may contribute to the restoration of the poloidal field as
part of the dynamo mechanism that controls the solar cycle. The solar minimum
at the transition from cycle 23 to 24 was notable for its low level of activity
and its extended length. It is of interest to study whether the convective
phenomena that influences the solar magnetic field during this time differed in
character to periods of previous minima. This study investigates three
characteristics (velocity components, sizes and lifetimes) of solar
supergranulation. Comparisons of these characteristics are made between the
minima of cycles 22/23 and 23/24 using MDI Doppler data from 1996 and 2008,
respectively. It is found that whereas the lifetimes are equal during both
epochs (around 18 h), the sizes are larger in 1996 (35.9 +/- 0.3 Mm) than in
2008 (35.0 +/- 0.3 Mm), while the dominant horizontal velocity flows are weaker
(139 +/- 1 m/s in 1996; 141 +/- 1 m/s in 2008). Although numerical differences
are seen, they are not conclusive proof of the most recent minimum being
inherently unusual.Comment: 22 pages, 5 figures. Solar Physics, in pres
Updated adolescent diagnostic criteria for polycystic ovary syndrome: impact on prevalence and longitudinal body mass index trajectories from birth to adulthood
Background: Polycystic ovary syndrome (PCOS) is challenging to diagnose. While the 2003 Rotterdam criteria are widely used for adults, the 2018 international PCOS guideline recommended updated Rotterdam criteria with both hyperandrogenism and oligo-anovulation for adolescents based on evidence-informed expert consensus. This study compared the prevalence of PCOS using updated and original Rotterdam criteria in community-based adolescents and explored long-term body mass index (BMI) trajectories across different diagnostic phenotypes. Methods: Overall, 227 postmenarchal adolescent females from the prospective cohort Raine Study undertook comprehensive PCOS assessment at age 14–16 years. Detailed anthropometric measurements were collected from birth until age 22 years. Cross-sectional and longitudinal BMI were analyzed using t tests and generalized estimating equations. Results: PCOS was diagnosed in 66 (29.1%) participants using original criteria versus 37 (16.3%) participants using updated Rotterdam criteria. Using updated criteria, participants with PCOS had higher BMI than participants without PCOS from prepubertal. Only the phenotype meeting the updated criteria was significantly associated with higher long-term BMI gain whereas other PCOS phenotypes had similar BMI trajectories to participants without PCOS (p < 0.001). Conclusions: The use of the 2018 updated Rotterdam criteria reduces over-diagnosis of PCOS in adolescents and identifies those at the greatest risk of long-term weight gain, a key contributor to disease severity and long-term health implications. The BMI trajectories of females with PCOS on updated criteria diverge prepubertally compared to those without PCOS. This work supports targeting adolescents diagnosed with PCOS on the 2018 updated criteria for early lifestyle interventions to prevent long-term health complications.Chau Thien Tay, Roger J. Hart, Martha Hickey, Lisa J. Moran, Arul Earnest, Dorota A. Doherty, Helena J. Teede and Anju E. Joha
Panspermia, Past and Present: Astrophysical and Biophysical Conditions for the Dissemination of Life in Space
Astronomically, there are viable mechanisms for distributing organic material
throughout the Milky Way. Biologically, the destructive effects of ultraviolet
light and cosmic rays means that the majority of organisms arrive broken and
dead on a new world. The likelihood of conventional forms of panspermia must
therefore be considered low. However, the information content of dam-aged
biological molecules might serve to seed new life (necropanspermia).Comment: Accepted for publication in Space Science Review
BAs and boride III-V alloys
Boron arsenide, the typically-ignored member of the III-V arsenide series
BAs-AlAs-GaAs-InAs is found to resemble silicon electronically: its Gamma
conduction band minimum is p-like (Gamma_15), not s-like (Gamma_1c), it has an
X_1c-like indirect band gap, and its bond charge is distributed almost equally
on the two atoms in the unit cell, exhibiting nearly perfect covalency. The
reasons for these are tracked down to the anomalously low atomic p orbital
energy in the boron and to the unusually strong s-s repulsion in BAs relative
to most other III-V compounds. We find unexpected valence band offsets of BAs
with respect to GaAs and AlAs. The valence band maximum (VBM) of BAs is
significantly higher than that of AlAs, despite the much smaller bond length of
BAs, and the VBM of GaAs is only slightly higher than in BAs. These effects
result from the unusually strong mixing of the cation and anion states at the
VBM. For the BAs-GaAs alloys, we find (i) a relatively small (~3.5 eV) and
composition-independent band gap bowing. This means that while addition of
small amounts of nitrogen to GaAs lowers the gap, addition of small amounts of
boron to GaAs raises the gap (ii) boron ``semi-localized'' states in the
conduction band (similar to those in GaN-GaAs alloys), and (iii) bulk mixing
enthalpies which are smaller than in GaN-GaAs alloys. The unique features of
boride III-V alloys offer new opportunities in band gap engineering.Comment: 18 pages, 14 figures, 6 tables, 61 references. Accepted for
publication in Phys. Rev. B. Scheduled to appear Oct. 15 200
Baryonium, tetra-quark state and glue-ball in large N_c QCD
From the large-N_c QCD point of view, baryonia, tetra-quark states, hybrids,
and glueballs are studied. The existence of these states is argued for. They
are constructed from baryons. In N_f=1 large N_c QCD, a baryonium is always
identical to a glueball with N_c valence gluons. The ground state 0^{-+}
glueball has a mass about 2450 MeV. f_0(1710) is identified as the lowest
0^{++} glueball. The lowest four-quark nonet should be f_0(1370), a_0(1450),
K^*_0(1430) and f_0(1500). Combining with the heavy quark effective theory,
spectra of heavy baryonia and heavy tetra-quark states are predicted. 1/N_c
corrections are discussed.Comment: 16 pages, 3 figure
First Observation of Coherent Production in Neutrino Nucleus Interactions with 2 GeV
The MiniBooNE experiment at Fermilab has amassed the largest sample to date
of s produced in neutral current (NC) neutrino-nucleus interactions at
low energy. This paper reports a measurement of the momentum distribution of
s produced in mineral oil (CH) and the first observation of coherent
production below 2 GeV. In the forward direction, the yield of events
observed above the expectation for resonant production is attributed primarily
to coherent production off carbon, but may also include a small contribution
from diffractive production on hydrogen. Integrated over the MiniBooNE neutrino
flux, the sum of the NC coherent and diffractive modes is found to be (19.5
1.1 (stat) 2.5 (sys))% of all exclusive NC production at
MiniBooNE. These measurements are of immediate utility because they quantify an
important background to MiniBooNE's search for
oscillations.Comment: Submitted to Phys. Lett.
Impact of interface energetic alignment and mobile ions on charge carrier accumulation and extraction in p‐i‐n perovskite solar cells
Understanding the kinetic competition between charge extraction and recombination, and how this is impacted by mobile ions, remains a key challenge in perovskite solar cells (PSCs). Here, this issue is addressed by combining operando photoluminescence (PL) measurements, which allow the measurement of real-time PL spectra during current–voltage (J–V) scans under 1-sun equivalent illumination, with the results of drift-diffusion simulations. This operando PL analysis allows direct comparison between the internal performance (recombination currents and quasi-Fermi-level-splitting (QFLS)) and the external performance (J–V) of a PSC during operation. Analyses of four PSCs with different electron transport materials (ETMs) quantify how a deeper ETM LUMO induces greater interfacial recombination, while a shallower LUMO impedes charge extraction. Furthermore, it is found that a low ETM mobility leads to charge accumulation in the perovskite under short-circuit conditions. However, thisalone cannot explain the remarkably high short-circuit QFLS of over 1 eV which is observed in all devices. Instead, drift-diffusion simulations allow this effect to be assigned to the presence of mobile ions which screen the internal electric field at short-circuit and lead to a reduction in the short-circuit current density by over 2 mA cm−2 in the best device
Health-related quality of life and fatigue in liver transplant recipients receiving tacrolimus versus sirolimus-based immunosuppression: results from a randomized trial
Background. The impact of different immunosuppression regimes on the health-related quality of life (HRQoL) and the severity of fatigue in liver transplant recipients is largely unknown. We investigated the impact of a sirolimus-based regimen compared with a tacrolimus (TAC)-based regimen on the HRQoL and the severity of fatigue.Methods. In this multicenter, open-label, randomized, controlled trial, 196 patients were randomized 90 d after transplantation to (1) once daily normal-dose TAC or (2) once daily combination therapy of low-dose sirolimus and TAC. HRQoL was measured with the EQ-5D-5L questionnaire, the EQ–visual analog scale, and the severity of fatigue questionnaire Fatigue Severity Score (FSS). The EQ-5D-5L scores were translated to societal values. We examined the HRQoL and the FSS over the course of the study by fitting generalized mixed-effect models.Results. Baseline questionnaires were available for 87.7% (172/196) of the patients. Overall, patients reported the least problems in the states of self-care and anxiety/depression and the most problems in the states of usual activities and pain/discomfort. No significant differences in HrQol and FSS were seen between the 2 groups. During follow-up, the societal values of the EQ-5D-5L health states and the patient’s self-rated EQ–visual analog scale score were a little lower than those of the general Dutch population in both study arms.Conclusions. The HRQoL and FSS were comparable in the 36 mo after liver transplantation in both study groups. The HRQoL of all transplanted patients approximated that of the general Dutch population, suggesting little to no residual symptoms in the long term after transplantation.Transplant surger
- …