Legislative History: An Act to Exempt Illegally Employed Minors from Worker\u27s Compensation Coverage (HP297)(LD 418)

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The pharmacology of recombinant hirudin, a new anticoagulant

A new anticoagulant, recombinant hirudin, was given to healthy volunteers (5 per test dose) in single .intravenous doses of 0,01, 0,02, 0,04, 0,07 and 0,1 mg/kg to study its anticoagulant effects, how it was tolerated and its pharmacokinetics. Hirudin proved to be a potent anticoagulant with important effects on thrombin (increase in thrombin time and partial thromboplastin time). The maximum pharmacodynamic effect was achieved with the 0,07 mg/kg dose, and upwards. All doses of the compound were tolerated without sideeffects. The mean elimination half-life is about 1 hour. Mean total clearance and volume of distribution are approximately 190 ml/min and 14 I, respectively. Hirudin obeys first-order pharmacokinetics

The outcome of babies 'of mothers with severe Rhesus incompatibility treated at Tygerberg Hospital, 1980 - 1993

No Abstract

Transcriptome profiling on the response of Mycosphaerella graminicola isolates to an azole fungicide using cDNA arrays

Resistance to azole antifungals is a major problem in the control of diseases caused by fungal pathogens of both humans and plants. Potential for the development of azole resistance in the wheat leaf blotch pathogen Mycosphaerella graminicola, the causal agent of the most economically significant foliar disease of wheat in north-western Europe, is now of particular concern after the recent emergence of widespread resistance to quinone outside inhibitor fungicides. Using a cDNA microarray representing around 25% of the genome, we have profiled the transcriptional response of M. graminicola to epoxiconazole, currently the most widely used azole fungicide on cereal crops. By comparing the transcription profiles of two M. graminicola isolates with contrasting sensitivities to epoxiconazole we show qualitative and quantitative differences in differentially expressed genes, including those involved in ergosterol biosynthesis, mitochondrial respiration and transport mechanisms. This represents the first study investigating the response of a plant pathogenic fungus to a fungicide using cDNA microarray technology

Partition Functions in Statistical Mechanics, Symmetric Functions, and Group Representations

Partition functions for non-interacting particles are known to be symmetric functions. It is shown that powerful group-theoretical techniques can be used not only to derive these relationships, but also to significantly simplify calculation of the partition functions for particles that carry internal quantum numbers. The partition function is shown to be a sum of one or more group characters. The utility of character expansions in calculating the partition functions is explored. Several examples are given to illustrate these techniques.Comment: 16 pages of RevTe

Photon production from a thermalized quark gluon plasma: quantum kinetics and nonperturbative aspects

We study the production of photons from a quark gluon plasma in local thermal equilibrium by introducing a non-perturbative formulation of the real time evolution of the density matrix. The main ingredient is the real time effective action for the electromagnetic field to $\mathcal{O}(\alpha_{em})$ and to all orders in $\alpha_s$. The real time evolution is completely determined by the solution of a \emph{classical stochastic} non-local Langevin equation which provides a Dyson-like resummation of the perturbative expansion. The Langevin equation is solved in closed form by Laplace transform in terms of the thermal photon polarization. A quantum kinetic description emerges directly from this formulation. We find that photons with $k \lesssim 200 ~{Mev}$ \emph{thermalize} as plasmon quasiparticles in the plasma on time scales $t \sim 10-20 ~{fm}/c$ which is of the order of the lifetime of the QGP expected at RHIC and LHC. We then obtain the direct photon yield to lowest order in $\alpha_{em}$ and to leading logarithmic order in $\alpha_s$ in a \emph{uniform} expansion valid at all time. The yield during a QGP lifetime $t \sim 10 ~{fm}/c$ is systematically larger than that obtained with the equilibrium formulation and the spectrum features a distinct flattening for $k \gtrsim 2.5 ~{Gev}$. We discuss the window of reliability of our results, the theoretical uncertainties in \emph{any} treatment of photon emission from a QGP in LTE and the shortcomings of the customary S-matrix approach.Comment: 31 pages. To appear in Nucl. Phys. A. New section (VII) with response to and criticism of hep-ph/031222

Dynamical renormalization group approach to relaxation in quantum field theory

The real time evolution and relaxation of expectation values of quantum fields and of quantum states are computed as initial value problems by implementing the dynamical renormalization group (DRG).Linear response is invoked to set up the renormalized initial value problem to study the dynamics of the expectation value of quantum fields. The perturbative solution of the equations of motion for the field expectation values of quantum fields as well as the evolution of quantum states features secular terms, namely terms that grow in time and invalidate the perturbative expansion for late times. The DRG provides a consistent framework to resum these secular terms and yields a uniform asymptotic expansion at long times. Several relevant cases are studied in detail, including those of threshold infrared divergences which appear in gauge theories at finite temperature and lead to anomalous relaxation. In these cases the DRG is shown to provide a resummation akin to Bloch-Nordsieck but directly in real time and that goes beyond the scope of Bloch-Nordsieck and Dyson resummations. The nature of the resummation program is discussed in several examples. The DRG provides a framework that is consistent, systematic and easy to implement to study the non-equilibrium relaxational dynamics directly in real time that does not rely on the concept of quasiparticle widths.Comment: LaTex, 27 pages, 2 .ps figure

Short-term post-harvest stress that affects profiles of volatile organic compounds and gene expression in rocket salad during early post-harvest senescence

Once harvested, leaves undergo a process of senescence which shares some features with developmental senescence. These include changes in gene expression, metabolites, and loss of photosynthetic capacity. Of particular interest in fresh produce are changes in nutrient content and the aroma, which is dependent on the profile of volatile organic compounds (VOCs). Leafy salads are subjected to multiple stresses during and shortly after harvest, including mechanical damage, storage or transport under different temperature regimes, and low light. These are thought to impact on later shelf life performance by altering the progress of post-harvest senescence. Short term stresses in the first 24 h after harvest were simulated in wild rocket (Diplotaxis tenuifolia). These included dark (ambient temperature), dark and wounding (ambient temperature), and storage at 4 \ub0C in darkness. The effects of stresses were monitored immediately afterwards and after one week of storage at 10 \ub0C. Expression changes in two NAC transcription factors (orthologues of ANAC059 and ANAC019), and a gene involved in isothiocyanate production (thiocyanate methyltransferase, TMT) were evident immediately after stress treatments with some expression changes persisting following storage. Vitamin C loss and microbial growth on leaves were also affected by stress treatments. VOC profiles were differentially affected by stress treatments and the storage period. Overall, short term post-harvest stresses affected multiple aspects of rocket leaf senescence during chilled storage even after a week. However, different stress combinations elicited different responses

Single step electrosynthesis of NiMnGa alloys

An electrochemical synthesis route for NiMnGa alloys is presented. Thin films of NiMnGa were fabricated by single step electrodeposition from aqueous electrolytes using direct current over a range of current densities. By electrolyte tuning, homogeneous films with high Ga and Mn content could be achieved at current densities as high as -400 mA cm-2. Detailed compositional analysis of the alloys showed that growth was homogeneous and oxygen content was minimized. Films plated at very low current densities were found to be nanocrystalline/amorphous. In order to obtain fully crystalline samples, thermal annealing was carried out. Mechanical characterization was assessed by nanoindentation, and the effect of Ga content on mechanical properties was investigated