Correlations of projectile like fragments in heavy ion reactions at Fermi energy

Correlations between pairs of projectile-like fragments, emitted by the system ${^{16}O}+{^{197}Au}$ at the laboratory bombarding energy of 515 MeV, have been studied under two stipulated conditions: (1) at least one member of the pair is emitted at an angle less than the grazing angle for the system, (2) both the members of the pair are emitted at angles larger than the grazing angle. A surprisingly large difference, by more than an order of magnitude, is found between the correlations for the two cases. This observation could be explained on the basis of a simple semi-classical break up model. Further analysis of the variation of the charge correlation function with the difference in the nuclear charges of the correlated pair showed trends which are consistent with an "inelastic break up process", in which the projectile breaks up at the radius of contact, in such a way that, one fragment (preferably the lighter) is emitted to one side within the grazing angle, while the other orbits around the target nucleus for a while and emerges on the other side, at a negative scattering angle, much like in a deep inelastic scattering.Comment: 19 pages, 12 figures accepted by Eurp. Physics Journal

MCSH, a lock with the standard interface

The MCS lock of Mellor-Crummey and Scott (1991), 23 pages. is a very efficient first-come first-served mutual-exclusion algorithm that uses the atomic hardware primitives fetch-and-store and compare-and-swap. However, it has the disadvantage that the calling thread must provide a pointer to an allocated record. This additional parameter violates the standard locking interface, which has only the lock as a parameter. Hence, it is impossible to switch to MCS without editing and recompiling an application that uses locks.This article provides a variation of MCS with the standard interface, which remains FCFS, called MCSH. One key ingredient is to stack allocate the necessary record in the acquire procedure of the lock, so its life-time only spans the delay to enter a critical section. A second key ingredient is communicating the allocated record between the acquire and release procedures through the lock to maintain the standard locking interface. Both of these practices are known to practitioners, but our solution combines them in a unique way. Furthermore, when these practices are used in prior papers, their correctness is often argued informally. The correctness of MCSH is verified rigorously with the proof assistant PVS, and experiments are run to compare its performance with MCS and similar locks

Model tests on the control behaviour of a test air supply system in open or closed-loop operation

The Leibniz Universität Hannover is currently establishing a new mechanical engineering campus which includes a new research building "Dynamics of Energy Conversion" (DEW). This building provides a large compressor station for either steady or dynamic (transient) operation of turbomachinery and power plant test rigs (e.g. air turbine, axial compressor, combustion chamber, planar cascade, acoustic wind tunnel). The test air supply system is designed to enable investigations under high load gradients over wide operating ranges with Reynolds and Mach numbers controlled independently in order to fulfil aerodynamic similarity conditions between reality and model experiments. This is achieved by closed loop operation of the test air supply system which allows independent adjustment of pressure, temperature and volume flow rate as well as independence from environmental influences such as temperature or humidity. The compressor station utilizes as first stage two parallel Roots-type PD compressors and as second stage two parallel screw compressors. The test rigs operate at expansion ratios between 1 and 6. Test rig inlet pressures range from 1 bar(abs) to 8 bar(abs) with a maximum mass flow rate of 25 kg/s. At all conditions temperatures can be regulated between 60°C and 200°C. The test air supply system has a maximum electric power input of approximately 6 MW. As stringent demands on stability and reproducibility have to be met and automatic operation was requested, a scaled and simplified but fully functional model of the test air supply system was built, mainly to enable testing of control methods and devices prior to their final implementation on site. The functional model uses DN150 piping and consists of one Roots-type PD compressor as first stage and one screw compressors as second stage. Both compressors are driven by electric motors regulated by frequency converters. A turbine test rig is represented in the model by an adjustable throttle valve. Precise control of the mass flow rate is provided by a cascaded adjustable bypass around the test rig. The paper describes the test air supply system and the scaled model and presents experimental results on the achievable stability of pressure, temperature and mass flow rate at the test rig inlet in steady operation at several operating conditions of the model

A temperature shock can lead to trans-generational immune priming in the Red Flour Beetle, Tribolium castaneum

Trans-generational immune priming (TGIP) describes the transfer of immune stimulation to the next generation. As stress and immunity are closely connected, we here address the question whether trans-generational effects on immunity and resistance can also be elicited by a nonpathogen stress treatment of parents. General stressors have been shown to induce immunity to pathogens within individuals. However, to our knowledge, it is as of yet unknown whether stress can also induce trans-generational effects on immunity and resistance. We exposed a parental generation (mothers, fathers, or both parents) of the red flour beetle Tribolium castaneum, a species where TGIP has been previously been demonstrated, to either a brief heat or cold shock and examined offspring survival after bacterial infection with the entomopathogen Bacillus thuringiensis. We also studied phenoloxidase activity, a key enzyme of the insect innate immune system that has previously been demonstrated to be up-regulated upon TGIP. We quantified parental fecundity and offspring developmental time to evaluate whether trans-generational priming might have costs. Offspring resistance was found to be significantly increased when both parents received a cold shock. Offspring phenoloxidase activity was also higher when mothers or both parents were cold-shocked. By contrast, parental heat shock reduced offspring phenoloxidase activity. Moreover, parental cold or heat shock delayed offspring development. In sum, we conclude that trans-generational priming for resistance could not only be elicited by pathogens or pathogen-derived components, but also by more general cues that are indicative of a stressful environment. The interaction between stress responses and the immune system might play an important role also for trans-generational effects

Dissociative recombination measurements of HCl+ using an ion storage ring

We have measured dissociative recombination of HCl+ with electrons using a merged beams configuration at the heavy-ion storage ring TSR located at the Max Planck Institute for Nuclear Physics in Heidelberg, Germany. We present the measured absolute merged beams recombination rate coefficient for collision energies from 0 to 4.5 eV. We have also developed a new method for deriving the cross section from the measurements. Our approach does not suffer from approximations made by previously used methods. The cross section was transformed to a plasma rate coefficient for the electron temperature range from T=10 to 5000 K. We show that the previously used HCl+ DR data underestimate the plasma rate coefficient by a factor of 1.5 at T=10 K and overestimate it by a factor of 3.0 at T=300 K. We also find that the new data may partly explain existing discrepancies between observed abundances of chlorine-bearing molecules and their astrochemical models.Comment: Accepted for publication in ApJ (July 7, 2013

Energy-sensitive imaging detector applied to the dissociative recombination of D2H+

We report on an energy-sensitive imaging detector for studying the fragmentation of polyatomic molecules in the dissociative recombination of fast molecular ions with electrons. The system is based on a large area (10 cm x 10 cm) position-sensitive, double-sided Si-strip detector with 128 horizontal and 128 vertical strips, whose pulse height information is read out individually. The setup allows to uniquely identify fragment masses and is thus capable of measuring branching ratios between different fragmentation channels, kinetic energy releases, as well as breakup geometries, as a function of the relative ion-electron energy. The properties of the detection system, which has been installed at the TSR storage ring facility of the Max-Planck Institute for Nuclear Physics in Heidelberg, is illustrated by an investigation of the dissociative recombination of the deuterated triatomic hydrogen cation D2H+. A huge isotope effect is observed when comparing the relative branching ratio between the D2+H and the HD+D channel; the ratio 2B(D2+H)/B(HD+D), which is measured to be 1.27 +/- 0.05 at relative electron-ion energies around 0 eV, is found to increase to 3.7 +/- 0.5 at ~5 eV.Comment: 11 pages, 12 figures, submitted to Physical Review

Reliability Of A Novel Intracardiac Electrogram Method For AV And VV Delay Optimization And Comparability To Echocardiography Procedure For Determining Optimal Conduction Delays In CRT Patients

Background: Echocardiography is widely used to optimize CRT programming. A novel intracardiac electrogram method (IEGM) was recently developed as an automated programmer-based method, designed to calculate optimal atrioventricular (AV) and interventricular (VV) delays and provide optimized delay values as an alternative to standard echocardiographic assessment.Objective: This study was aimed at determining the reliability of this new method. Furthermore the comparability of IEGM to existing echocardiographic parameters for determining optimal conduction delays was verified.Methods: Eleven patients (age 62.9± 8.7; 81% male; 73% ischemic), previously implanted with a cardiac resynchronisation therapy defibrillator (CRT-D) underwent both echocardiographic and IEGM-based delay optimization.Results: Applying the IEGM method, concordance of three consecutively performed measurements was found in 3 (27%) patients for AV delay and in 5 (45%) patients for VV delay. Intra-individual variation between three measurements as assessed by the IEGM technique was up to 20 ms (AV: n=6; VV: n=4). E-wave, diastolic filling time and septal-to-lateral wall motion delay emerged as significantly different between the echo and IEGM optimization techniques (p < 0.05). The final AV delay setting was significantly different between both methods (echo: 126.4 ± 29.4 ms, IEGM: 183.6 ± 16.3 ms; p < 0.001; correlation: R = 0.573, p = 0.066). VV delay showed significant differences for optimized delays (echo: 46.4 ± 23.8 ms, IEGM: 10.9 ± 7.0 ms; p <0.01; correlation: R = -0.278, p = 0.407).Conclusion: The automated programmer-based IEGM-based method provides a simple and safe method to perform CRT optimization. However, the reliability of this method appears to be limited. Thus, it remains difficult for the examiner to determine the optimal hemodynamic settings. Additionally, as there was no correlation between the optimal AV- and VV-delays calculated by the IEGM method and the echo optimization, the use of the IEGM method and the comparability to the echo has not been definitely clarified

Spectroscopy and dissociative recombination of the lowest rotational states of H3+

The dissociative recombination of the lowest rotational states of H3+ has been investigated at the storage ring TSR using a cryogenic 22-pole radiofrequency ion trap as injector. The H3+ was cooled with buffer gas at ~15 K to the lowest rotational levels, (J,G)=(1,0) and (1,1), which belong to the ortho and para proton-spin symmetry, respectively. The rate coefficients and dissociation dynamics of H3+(J,G) populations produced with normal- and para-H2 were measured and compared to the rate and dynamics of a hot H3+ beam from a Penning source. The production of cold H3+ rotational populations was separately studied by rovibrational laser spectroscopy using chemical probing with argon around 55 K. First results indicate a ~20% relative increase of the para contribution when using para-H2 as parent gas. The H3+ rate coefficient observed for the para-H2 source gas, however, is quite similar to the H3+ rate for the normal-H2 source gas. The recombination dynamics confirm that for both source gases, only small populations of rotationally excited levels are present. The distribution of 3-body fragmentation geometries displays a broad part of various triangular shapes with an enhancement of ~12% for events with symmetric near-linear configurations. No large dependences on internal state or collision energy are found.Comment: 10 pages, 9 figures, to be published in Journal of Physics: Conference Proceeding

Evaluation of Policy Scenarios for the 1990 Farm Bill

Three alternatives for 1990 farm legislation are examined: (1) a continuation of current legislation; (2) small reductions in producer support levels that are phased in after a two-year delay; and (3) more significant policy reforms that include immediate support reductions for grains and cotton, marketing quotas for dairy products and sugar, and an expanded conservation reserve. Analysis indicates that the alternatives to current policies reduce both government outlays on farm programs and net farm income. The effects on the supply, demand, and prices of most crop and livestock commodities are small. Marketing quotas protect sugar and dairy producer income and allow increased imports without significant budgetary effects, but at considerable cost to consumers

Collagen type XVIII/endostatin is differentially expressed in primary and metastatic colorectal cancers and ovarian carcinomas

Collagen type XVIII (C18) is a nonfibrillar collagen of basement membranes. Its C-terminal fragment, endostatin, has been identified as an inhibitor of angiogenesis. C18 is predominantly expressed by hepatocytes of normal, cirrhotic and neoplastic liver. We compared the patterns of C18 RNA-expression in colonic adenocarcinoma metastases, which represent the most frequently occurring liver tumours, to normal colon mucosa, to primary colon cancers and to ovarian cancers which are often morphologically similar to colonic cancer or metastasis. Two C18-specific RNA-probes were generated to perform in situ hybridization combined with immunohistochemistry for cytokeratin, vimentin and the endothelial marker CD31, in order to characterize the C18-expressing cells. C18/endostatin protein was localized by immunohistology. In colorectal carcinomas and their liver metastases high levels of C18 transcripts were observed in endothelial cells and fibroblasts/myofibroblasts, whereas C18 RNA was virtually absent from carcinoma cells. Ovarian carcinomas displayed high C18 RNA expression both in carcinoma and stromal cells, indicating that induction of C18 transcription in tumour stromal cells is independent of the ability of carcinoma cells to express C18. While the role of tumour cell derived C18 in cancer growth regulation remains unknown, stimulation of proteolysis of the locally strongly expressed C18 to endostatin could offer an attractive approach for a targeted antineoplastic therapy. © 2001 Cancer Research Campaign   http://www.bjcancer.co