3,138 research outputs found
Apidae aus Süd-Ost-Afrika gesammelt von Missionar Henri A. Junod Dr. phil. h. c. (1863-1934) (Hym. Apid.)
Dem grossen Interesse, welches Herr Missionar Junod während
seiner amtlichen Tätigkeit in N.-Transvaal und der Delagoa Bai der
Insektenwelt schenkte, verdanken wir höchst wertvolle Funde, die
im folgenden zusammengestellt wurden.Peer reviewe
Optical alignment and spinning of laser-trapped microscopic particles
Light-induced rotation of absorbing microscopic particles by transfer of
angular momentum from light to the material raises the possibility of optically
driven micromachines. The phenomenon has been observed using elliptically
polarized laser beams or beams with helical phase structure. But it is
difficult to develop high power in such experiments because of overheating and
unwanted axial forces, limiting the achievable rotation rates to a few hertz.
This problem can in principle be overcome by using transparent particles,
transferring angular momentum by a mechanism first observed by Beth in 1936,
when he reported a tiny torque developed in a quartz waveplate due to the
change in polarization of transmitted light. Here we show that an optical
torque can be induced on microscopic birefringent particles of calcite held by
optical tweezers. Depending on the polarization of the incident beam, the
particles either become aligned with the plane of polarization (and thus can be
rotated through specified angles) or spin with constant rotation frequency.
Because these microscopic particles are transparent, they can be held in
three-dimensional optical traps at very high power without heating. We have
observed rotation rates in excess of 350 Hz.Comment: 4 pages, 4 figure
Open-Ended Recursive Calculation of Single Residues of Response Functions for Perturbation-Dependent Basis Sets
Accepted manuscript version. Published version at http://doi.org/10.1021/acs.jctc.5b00646.We present theory, implementation, and applications of a recursive scheme for the calculation of single residues of response functions that can treat perturbations that affect the basis set. This scheme enables the calculation of nonlinear light absorption properties to arbitrary order for other perturbations than an electric field. We apply this scheme for the first treatment of two-photon circular dichroism (TPCD) using London orbitals at the Hartree–Fock level of theory. In general, TPCD calculations suffer from the problem of origin dependence, which has so far been solved by using the velocity gauge for the electric dipole operator. This work now enables comparison of results from London orbital and velocity gauge based TPCD calculations. We find that the results from the two approaches both exhibit strong basis set dependence but that they are very similar with respect to their basis set convergence
Calculation and optical measurement of laser trapping forces on non-spherical particles
Optical trapping, where microscopic particles are trapped and manipulated by
light is a powerful and widespread technique, with the single-beam gradient
trap (also known as optical tweezers) in use for a large number of biological
and other applications.
The forces and torques acting on a trapped particle result from the transfer
of momentum and angular momentum from the trapping beam to the particle.
Despite the apparent simplicity of a laser trap, with a single particle in a
single beam, exact calculation of the optical forces and torques acting on
particles is difficult. Calculations can be performed using approximate
methods, but are only applicable within their ranges of validity, such as for
particles much larger than, or much smaller than, the trapping wavelength, and
for spherical isotropic particles.
This leaves unfortunate gaps, since wavelength-scale particles are of great
practical interest because they are readily and strongly trapped and are used
to probe interesting microscopic and macroscopic phenomena, and non-spherical
or anisotropic particles, biological, crystalline, or other, due to their
frequent occurance in nature, and the possibility of rotating such objects or
controlling or sensing their orientation.
The systematic application of electromagnetic scattering theory can provide a
general theory of laser trapping, and render results missing from existing
theory. We present here calculations of force and torque on a trapped particle
obtained from this theory and discuss the possible applications, including the
optical measurement of the force and torque.Comment: 10 pages, 5 figure
Pregnancy-associated breast cancer - Special features in diagnosis and treatment
For obvious psychological reasons it is difficult to associate pregnancy - a life-giving period of our existence with life-threatening malignancies. Symptoms pointing to malignancy are often ignored by both patients and physicians, and this, together with the greater difficulty of diagnostic imaging, probably results in the proven delay in the detection of breast cancers during pregnancy. The diagnosis and treatment of breast cancer are becoming more and more important, as the fulfillment of the desire to have children is increasingly postponed until a later age associated with a higher risk of carcinoma, and improved cure rates of solid tumors no longer exclude subsequent pregnancies. The following article summarizes the special features of the diagnosis and primary therapy of pregnancy-associated breast cancer with particular consideration of cytostatic therapy
N-glycans of human amniotic fluid transferrin stimulate progesterone production in human first trimester trophoblast cells in vitro
Aims: During pregnancy, the placenta produces a variety of steroid hormones and proteins. Several of these substances have been shown to exert immunomodulatory effects. Progesterone is thought to mediate some of these effects by regulating uterine responsiveness. The aim of this study was to clarify the effect of amniotic fluid transferrin and its N-glycans on the release of progesterone by first trimester trophoblast cells in vitro. Methods: Cytotrophoblast cells were prepared from human first trimester placentae by trypsin-DNAse dispersion of villous tissue followed by a percoll gradient centrifugation and depletion of CD45 positive cells by magnetic cell sorting. Trophoblasts were incubated with varying concentrations (50-300 mug/ml) of transferrin from human amniotic fluid and serum as well as with N-glycans obtained from amniotic fluid transferrin. Culture supernatants were assayed for progesterone by enzyme-immunometric methods. Results: The release of progesterone increased in amniotic fluid transferrin- and N-glycan-treated trophoblast cell cultures compared to untreated trophoblast cells. There was no stimulating effect of serum transferrin on the progesterone production of trophoblast cells. Conclusions: The results suggest that amnion-transferrin and especially its N-glycans modulate the endocrine function of trophoblasts in culture by up regulating progesterone secretion
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