Organizational climate during the post-pandemic: Study of the administrative area of a company in the logistics sector

El clima organizacional es uno de los elementos más importantes en el abordaje y comprensión de las dinámicas laborales que suceden dentro de las empresas en la actualidad; especialmente durante la época de la postpandemia en Colombia a partir del fin del confinamiento. Con base a ello, este estudio se presenta con el objetivo de medir el Clima organizacional del área administrativa de una empresa del sector logístico de la ciudad de Barranquilla (Colombia). En el ámbito metodológico, se destaca que la mencionada investigación se desarrolló desde el enfoque positivista, siendo un estudio de tipo descriptivo con un diseño no experimental y de campo. La muestra estuvo constituida por 46 trabajadores de una empresa del sector logístico de en la ciudad Barranquilla, a quienes se les aplicó un instrumento desarrollado por Litwig y Stringer. Los resultados permitieron observar niveles considerados como desfavorables del clima organizacional dentro de la organización, especialmente en las dimensiones Estructura, Responsabilidad, Recompensa, Riesgo, Calidez, Apoyo y Conflicto. Se concluye que en estos casos de una percepción desfavorable es recomendable la puesta en marcha de estrategias encaminadas a la intervención del clima organizacional, comenzando por una auditoria estructural sobre las dimensiones con resultados más bajos.The organizational climate is one of the most important elements in the approach and understanding of the labor dynamics that occur within companies today; especially during the post-pandemic era in Colombia after the end of the confinement. Based on this, this study is presented with the objective of measuring the organizational climate of the administrative area of ​​a company in the logistics sector in the city of Barranquilla (Colombia). In the methodological field, it is highlighted that the aforementioned research was developed from the positivist approach, being a descriptive study with a non-experimental and field design. The sample consisted of 46 workers from a company in the logistics sector in the city of Barranquilla, to whom an instrument developed by Litwig y Stringer was applied. The results allowed us to observe levels considered unfavorable in the organizational climate within the organization, especially in the dimensions Structure, Responsibility, Reward, Risk, Warmth, Support and Conflict. It is concluded that in these cases of an unfavorable perception, the implementation of strategies aimed at intervening in the organizational climate is recommended, starting with a structural audit on the dimensions with the lowest results

El color en la arquitectura y en su representación gráfica: Percepción, interpretación y representación

Este texto presenta algunos de los temas investigados en la Red del curso académico 2015-2016 de título homónimo que continúa con la estrategia de ediciones anteriores de este proyecto de investigación en docencia desarrollado por un grupo de profesores en el Área de Expresión Gráfica Arquitectónica (E.G.A.). Hemos tenido la suerte de contar con un investigador con dilatada experiencia en estos temas, Jorge Llopis, de la Universidad Politécnica de Valencia, lo que ha contribuido a enriquecer el debate en el seno de la red. En esta ocasión, se decidió centrar las investigaciones en torno al tema color en la arquitectura y en su representación. El texto, por ello, desarrolla aspectos tanto vinculados a la percepción del color como variable arquitectónica, por un lado, y el uso del color como recurso expresivo y variable gráfica empleado de diversas maneras en las distintas asignaturas del área, ya sea como recurso docente o como competencia a adquirir por parte de nuestros alumnos

Fenomenología y percepción en arquitectura. De la escala 1/1 a la miniaturización de los modelos físicos y virtuales

Este texto presenta algunos de los aspectos investigados en el seno de la Red del curso académico 2014-2015, “Fenomenología y percepción en arquitectura. De la escala 1/1 a la miniaturización de los modelos físicos y virtuales”, que se habían planteado al constituir la misma y que suponen una cierta continuidad con las ediciones anteriores del Proyecto Redes que ha venido desarrollando un grupo de profesores en el Área de Expresión Gráfica Arquitectónica (E.G.A.) en el Grado en Arquitectura de la U.A. –ahora Fundamentos de la Arquitectura- dentro del contexto del E.E.E.S. En esta ocasión, se decidió centrar las investigaciones en torno al tema de las maquetas y los modelos virtuales como representación a escala de la arquitectura. Aprovechando la posibilidad que ofrece el programa de Redes de incluir a profesores de otras universidades que por su conocimiento en el ámbito de la investigación en los temas a abordar pudieran contribuir a enriquecer el debate en el seno de la misma decidimos invitar a los doctores Eduardo Carazo Lefort, de la Escuela Técnica Superior de Arquitectura de Valladolid, y Joel Olivares Ruiz, de la Universidad Gestalt de Diseño de Méjico; ambos han contribuido a las labores de la red. Siguiendo con la dinámica establecida en anteriores ediciones se invitó al profesor Carazo a que planteara en el seno de la Red las experiencias docentes desarrolladas dentro del área de conocimiento de Expresión Gráfica Arquitectónica (E.G.A.) de su universidad, lo que se hizo a puerta abierta invitando a todos los profesores del área homónima de la U.A. Por otro lado, se han presentado tres comunicaciones a las XIII Jornadas de Redes de Investigación en Docencia de la UA desarrolladas por profesores de la Red (Allepuz, Marcos 2015, Juan 2015, Marcos, Olivares 2015). La primera de ellas versa acerca de las reflexiones de Goodman o Bafna respecto del dibujo de arquitectura, su vinculación con otras manifestaciones artísticas y el análisis cognitivo de las mismas; la segunda de ellas aborda la cuestión de una enseñanza de asignaturas de E.G.A. en un contexto digital, y la tercera plantea cuestiones en relación con el enfoque cognitivo en la pedagogía de la arquitectura. Se ha decidido centrar, por ello, el discurso de esta investigación en el tema de las maquetas que servía de título a la red planteada este año

Effects of Fe deficiency on the protein profiles and lignin composition of stem tissues from Medicago truncatula in absence or presence of calcium carbonate

12 Pags.- 2 Tabls.- 5 Figs.- Supp. Data.Iron deficiency is a yield-limiting factor with major implications for crop production, especially in soils with high CaCO3. Because stems are essential for the delivery of nutrients to the shoots, the aim of this work was to study the effects of Fe deficiency on the stem proteome of Medicago truncatula. Two-dimensional electrophoresis separation of stem protein extracts resolved 276 consistent spots in the whole experiment. Iron deficiency in absence or presence of CaCO3 caused significant changes in relative abundance in 10 and 31 spots, respectively, and 80% of them were identified by mass spectrometry. Overall results indicate that Fe deficiency by itself has a mild effect on the stem proteome, whereas Fe deficiency in the presence of CaCO3 has a stronger impact and causes changes in a larger number of proteins, including increases in stress and protein metabolism related proteins not observed in the absence of CaCO3. Both treatments resulted in increases in cell wall related proteins, which were more intense in the presence of CaCO3. The increases induced by Fe-deficiency in the lignin per protein ratio and changes in the lignin monomer composition, assessed by pyrolysis-gas chromatography–mass spectrometry and microscopy, respectively, further support the existence of cell wall alterations. Biological significance: In spite of being essential for the delivery of nutrients to the shoots, our knowledge of stem responses to nutrient deficiencies is very limited. The present work applies 2-DE techniques to unravel the response of this understudied tissue to Fe deficiency. Proteomics data, complemented with mineral, lignin and microscopy analyses, indicate that stems respond to Fe deficiency by increasing stress and defense related proteins, probably in response of mineral and osmotic unbalances, and eliciting significant changes in cell wall composition. The changes observed are likely to ultimately affect solute transport and distribution to the leaves.Work supported by the Spanish Ministry of Science and Competitiveness (MINECO; projects AGL2012-31988, AGL2011-25379 and AGL2013-42175-R, co-financed by FEDER), the Aragón Government (group A03), and the US Department of Agriculture, Agricultural Research Service (under Agreement number 58-6250-0-008 to MAG). Support was obtained by contracts I3P-CSIC (JRC), FPI-MINECO (GL and LC-L), JAE-PRE-CSIC (EG-C) and JAE-DOC-CSIC (JR), co-financed by the European Social Fund.Peer reviewe

Bentonite mechanical evolution – experimental work for the support of model development and validation

The objectives of the Beacon experimental studies are to provide input data and parameters for development and validation of models and to reduce uncertainties about conditions and phenomena influencing bentonite homogenisation. Both the homogenisation of an initially inhomogeneous bentonite system and the persistence or development of inhomogeneities in the bentonite system under various mechanical and hydraulic conditions are investigated. Eight experiment teams perform tests involving different bentonite materials and different hydraulic and mechanical boundary conditions. The experiments performed within Beacon address the hydro-mechanical behaviour of macroscopically homogeneous bentonite materials, (the influence of initial granulometry and of hydro-mechanical paths on the final properties of bentonite, constant load and constant volume tests on the Czech Cerny vrch bentonite), the issue of swelling into a limited void (experiments performed in constant volume cells partially filled with bentonite, at different scales and with different emphases), binary mixtures or artificial inhomogeneities (experiments using bentonite block/pellet or pellet/powder mixtures, and the influence of the degree of saturation on the shearing behaviour at a bentonite – steel interface. This report is the first Beacon WP4 deliverable on experimental work and presents the status at Beacon mid-term

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

Post-intervention Status in Patients With Refractory Myasthenia Gravis Treated With Eculizumab During REGAIN and Its Open-Label Extension

OBJECTIVE: To evaluate whether eculizumab helps patients with anti-acetylcholine receptor-positive (AChR+) refractory generalized myasthenia gravis (gMG) achieve the Myasthenia Gravis Foundation of America (MGFA) post-intervention status of minimal manifestations (MM), we assessed patients' status throughout REGAIN (Safety and Efficacy of Eculizumab in AChR+ Refractory Generalized Myasthenia Gravis) and its open-label extension. METHODS: Patients who completed the REGAIN randomized controlled trial and continued into the open-label extension were included in this tertiary endpoint analysis. Patients were assessed for the MGFA post-intervention status of improved, unchanged, worse, MM, and pharmacologic remission at defined time points during REGAIN and through week 130 of the open-label study. RESULTS: A total of 117 patients completed REGAIN and continued into the open-label study (eculizumab/eculizumab: 56; placebo/eculizumab: 61). At week 26 of REGAIN, more eculizumab-treated patients than placebo-treated patients achieved a status of improved (60.7% vs 41.7%) or MM (25.0% vs 13.3%; common OR: 2.3; 95% CI: 1.1-4.5). After 130 weeks of eculizumab treatment, 88.0% of patients achieved improved status and 57.3% of patients achieved MM status. The safety profile of eculizumab was consistent with its known profile and no new safety signals were detected. CONCLUSION: Eculizumab led to rapid and sustained achievement of MM in patients with AChR+ refractory gMG. These findings support the use of eculizumab in this previously difficult-to-treat patient population. CLINICALTRIALSGOV IDENTIFIER: REGAIN, NCT01997229; REGAIN open-label extension, NCT02301624. CLASSIFICATION OF EVIDENCE: This study provides Class II evidence that, after 26 weeks of eculizumab treatment, 25.0% of adults with AChR+ refractory gMG achieved MM, compared with 13.3% who received placebo

Minimal Symptom Expression' in Patients With Acetylcholine Receptor Antibody-Positive Refractory Generalized Myasthenia Gravis Treated With Eculizumab

The efficacy and tolerability of eculizumab were assessed in REGAIN, a 26-week, phase 3, randomized, double-blind, placebo-controlled study in anti-acetylcholine receptor antibody-positive (AChR+) refractory generalized myasthenia gravis (gMG), and its open-label extension

Experiencias en el aula: tercer encuentro de prácticas pedagógicas innovadoras.

Experiencias de profesores en su quehacer en los distintos ambientes de aprendizaje presenciales y a distancia.Para el Centro de Excelencia Docente aeiou constituye un honor presentar la publicación del Tercer Encuentro de Prácticas Pedagógicas Innovadoras en el que se destacan cuarenta trabajos de profesores de UNIMINUTO provenientes de diferentes sedes. Con este encuentro son ya tres que bajo la dirección de aeiou los profesores han compartido su quehacer en los distintos ambientes de aprendizaje presenciales y a distancia. Cada año el Centro de Excelencia Docente invita a los profesores a participar en este evento, para el 2108 además de la inscripción voluntaria por parte de cada profesor, se invitó al estudiantado a que postularan a sus profesores que consideraban eran innovadores y creativos en el cumplimiento de su función docente y se obtuvo una respuesta importante por parte de los estudiantes, que para algunos profesores resultó sorpresiva porque quizás no habían considerado que el trabajo que hacían en su ambiente de aprendizaje era diferente, fuera de lo común. Luego de una evaluación de jurados nacionales e internacionales de las prácticas presentadas y de la realización del evento, que tuvo como novedad hacerlo de forma simultánea en cuatro sedes donde UNIMINUTO tiene presencia: Buga, Ibagué, Pereira y Bogotá, se comparte la presente publicación para tener como referencia y evidencia el trabajo que los profesores hacen a diario

A Middle Palaeolithic wooden digging stick from Aranbaltza III, Spain

Aranbaltza is an archaeological complex formed by at least three open-air sites. Between 2014 and 2015 a test excavation carried out in Aranbaltza III revealed the presence of a sand and clay sedimentary sequence formed in floodplain environments, within which six sedimentary units have been identified. This sequence was formed between 137±50 ka, and includes several archaeological horizons, attesting to the long-term presence of Neanderthal communities in this area. One of these horizons, corresponding with Unit 4, yielded two wooden tools. One of these tools is a beveled pointed tool that was shaped through a complex operational sequence involving branch shaping, bark peeling, twig removal, shaping, polishing, thermal exposition and chopping. A use-wear analysis of the tool shows it to have traces related with digging soil so it has been interpreted as representing a digging stick. This is the first time such a tool has been identified in a European Late Middle Palaeolithic context; it also represents one of the first well-preserved Middle Palaeolithic wooden tool found in southern Europe. This artefact represents one of the few examples available of wooden tool preservation for the European Palaeolithic, allowing us to further explore the role wooden technologies played in Neanderthal communities