Strategic business model typologies evident in the Chinese real-estate industry

The Chinese real estate industry has emerged over recent decades as one of the key drivers of Chinese economic growth and attracted thousands of players nationwide. Yet, despite the continuing importance of the real-estate industry in China, there has not been any work done to identify nor describe the strategic business models used by enterprises within the sector. This study fills this gap in the literature. This paper begins by building a framework for studying the strategic business models used within the Chinese real-estate industry, and then goes on to identify the generic models that exist in the industry. A two-step cluster analysis of 117 Chinese real-estate companies was carried out over seven parameters identified in the literature as impacting business models: 1) clients, 2) products offered, 3) market locale, 4) financial structure, 5) value chain embeddedness, 6) core competency, and, 7) revenue source. Five generic strategic business models that characterize the Chinese real-estate industry were identified: 1) commercial property model, 2) government servicing model, 3) cost efficiency model, 4) asset management model, and, 5) high-turnover model. The findings will assist industry practitioners in evaluating and informing their own competitive positions within the Chinese real-estate industry

Advances in the study of B cells in renal ischemia-reperfusion injury

Renal ischemia-reperfusion injury (IRI) is a non-negligible clinical challenge for clinicians in surgeries such as renal transplantation. Functional loss of renal tubular epithelial cell (TEC) in IRI leads to the development of acute kidney injury, delayed graft function (DGF), and allograft rejection. The available evidence indicates that cellular oxidative stress, cell death, microvascular dysfunction, and immune response play an important role in the pathogenesis of IRI. A variety of immune cells, including macrophages and T cells, are actively involved in the progression of IRI in the immune response. The role of B cells in IRI has been relatively less studied, but there is a growing body of evidence for the involvement of B cells, which involve in the development of IRI through innate immune responses, adaptive immune responses, and negative immune regulation. Therefore, therapies targeting B cells may be a potential direction to mitigate IRI. In this review, we summarize the current state of research on the role of B cells in IRI, explore the potential effects of different B cell subsets in the pathogenesis of IRI, and discuss possible targets of B cells for therapeutic aim in renal IRI

An evaluation of urban renewal policies of Shenzhen, China

Urban renewal is a pragmatic approach in the sustainable urban development of urban areas, and has now become an essential strategy for most metropolises in China. The question of how urban renewal can best be realized has gained the attention of urban planning researchers looking to formulate practical evidence-based urban renewal policies through policy instruments. This paper analyzes the urban renewal policies of Shenzhen, a pioneer city in China in the promulgation of urban renewal legislation. In doing so, an analytical framework is established by focusing on three main policy instruments, along with several sub-instruments within them. Shenzhen’s five main urban renewal policies, issued between 2009 and 2016, are analyzed through this framework. Content analysis and pattern-matching is used in the review and analysis of the data. The results show that “Environment” side policies tend to be the most widely applied by the Shenzhen municipal government. Additionally, “Regulation Control” and “Goal-planning” policies are the two instruments most frequently adopted as sub-instruments. Moreover, it is found that the application of “Supply” side polices and “Demand” side polices needs be strengthened. These findings identify the types of urban renewal policies currently employed in China and provide a clear understanding of the current policy priorities, with suggestions and insight into further urban renewal policy initiatives for Shenzhen and beyond

Prediction of liver cancer prognosis based on immune cell marker genes

IntroductionMonitoring the response after treatment of liver cancer and timely adjusting the treatment strategy are crucial to improve the survival rate of liver cancer. At present, the clinical monitoring of liver cancer after treatment is mainly based on serum markers and imaging. Morphological evaluation has limitations, such as the inability to measure small tumors and the poor repeatability of measurement, which is not applicable to cancer evaluation after immunotherapy or targeted treatment. The determination of serum markers is greatly affected by the environment and cannot accurately evaluate the prognosis. With the development of single cell sequencing technology, a large number of immune cell-specific genes have been identified. Immune cells and microenvironment play an important role in the process of prognosis. We speculate that the expression changes of immune cell-specific genes can indicate the process of prognosis.MethodTherefore, this paper first screened out the immune cell-specific genes related to liver cancer, and then built a deep learning model based on the expression of these genes to predict metastasis and the survival time of liver cancer patients. We verified and compared the model on the data set of 372 patients with liver cancer.ResultThe experiments found that our model is significantly superior to other methods, and can accurately identify whether liver cancer patients have metastasis and predict the survival time of liver cancer patients according to the expression of immune cell-specific genes.DiscussionWe found these immune cell-specific genes participant multiple cancer-related pathways. We fully explored the function of these genes, which would support the development of immunotherapy for liver cancer

Spin-phonon scattering-induced low thermal conductivity in a van der Waals layered ferromagnet Cr2_2Si2_2Te6_6

Layered van der Waals (vdW) magnets are prominent playgrounds for developing magnetoelectric, magneto-optic and spintronic devices. In spintronics, particularly in spincaloritronic applications, low thermal conductivity ($\kappa$) is highly desired. Here, by combining thermal transport measurements with density functional theory calculations, we demonstrate low $\kappa$ down to 1 W m$^{-1}$ K$^{-1}$ in a typical vdW ferromagnet Cr$_2$Si$_2$Te$_6$. In the paramagnetic state, development of magnetic fluctuations way above $T_\mathrm{c}=$ 33 K strongly reduces $\kappa$ via spin-phonon scattering, leading to low $\kappa \sim$ 1 W m$^{-1}$ K$^{-1}$ over a wide temperature range, in comparable to that of amorphous silica. In the magnetically ordered state, emergence of resonant magnon-phonon scattering limits $\kappa$ below $\sim$ 2 W m$^{-1}$ K$^{-1}$, which would be three times larger if magnetic scatterings were absent. Application of magnetic fields strongly suppresses the spin-phonon scattering, giving rise to large enhancements of $\kappa$. Our calculations well capture these complex behaviours of $\kappa$ by taking the temperature- and magnetic-field-dependent spin-phonon scattering into account. Realization of low $\kappa$ which is easily tunable by magnetic fields in Cr$_2$Si$_2$Te$_6$, may further promote spincaloritronic applications of vdW magnets. Our theoretical approach may also provide a generic understanding of spin-phonon scattering, which appears to play important roles in various systems.Comment: 14 pages, 6 figures, accepted for publication in Advanced Functional Material

An Evaluation of Urban Renewal Policies of Shenzhen, China

Urban renewal is a pragmatic approach in the sustainable urban development of urban areas, and has now become an essential strategy for most metropolises in China. The question of how urban renewal can best be realized has gained the attention of urban planning researchers looking to formulate practical evidence-based urban renewal policies through policy instruments. This paper analyzes the urban renewal policies of Shenzhen, a pioneer city in China in the promulgation of urban renewal legislation. In doing so, an analytical framework is established by focusing on three main policy instruments, along with several sub-instruments within them. Shenzhen’s five main urban renewal policies, issued between 2009 and 2016, are analyzed through this framework. Content analysis and pattern-matching is used in the review and analysis of the data. The results show that “Environment” side policies tend to be the most widely applied by the Shenzhen municipal government. Additionally, “Regulation Control” and “Goal-planning” policies are the two instruments most frequently adopted as sub-instruments. Moreover, it is found that the application of “Supply” side polices and “Demand” side polices needs be strengthened. These findings identify the types of urban renewal policies currently employed in China and provide a clear understanding of the current policy priorities, with suggestions and insight into further urban renewal policy initiatives for Shenzhen and beyond

Study on the Preparation of Biochar Ceramsite Based on Sewage Sludge and the Characterization of Its Properties

Biochar ceramsite was prepared from residual sludge at different temperatures. Specific surface area, compressive strength, and toxic leaching tests were used to compare the properties. Through tests and scanning electron microscopy (SEM), it was found that with the increase of preparation temperature, the ceramsite showed higher porosity, larger specific surface area, and better compressive strength. The leaching amount of toxic heavy metals is low when the temperature is higher than 650 °C. According to X-ray diffraction (XRD) analysis, the main component of sludge is quartz. There were amounts of iron and aluminum in sludge, which were the main reason for its good adsorption efficiency. Through the adsorption experiment on Cr(VI), it was found that the adsorption efficiency of the ceramsite on Cr(VI) was better at low pH, and the adsorption isotherm fitted well with Langmuir and Freundlich types. The adsorption process had both monolayer adsorption and multilayer adsorption, and the adsorption process was in line with the pseudo-second-order kinetics

Key Variables for Decision-Making on Urban Renewal in China: A Case Study of Chongqing

Currently, the Chinese government leads urban renewal via a top-down management style with the government playing the role of decision-maker. The decision-making opinions held by groups of stakeholders are divided, which creates many social problems, project technical issues and even civil disorder. This paper uses factor analysis to extract the key variables for decision-making on urban renewal and the entropy weight method to sort these key variables by importance. Based on this order, the differing opinions of stakeholders regarding urban renewal decision-making are explored. First, contradictory opinions exist concerning the importance of the ecological environment, housing and facilities, social welfare and commercial activities, which are the main driving forces behind urban renewal, due to the groups of stakeholders having different interest demands. Second, these varying interest demands of the stakeholders affect the urban renewal decision-making results. Finally, compensation to people for the demolition of their homes, infrastructure supplements and the investment behaviour of developers display the greatest lack of consensus of all the variables tested in urban renewal decision-making between different stakeholders