1,375 research outputs found
Ferromagnetism, glassiness, and metastability in a dilute dipolar-coupled magnet
We have measured the ac magnetic susceptibility of the model dilute dipolar-coupled Ising system LiHo_xY_(1−x)F_4. The x=0.46 material displays an ordinary ferromagnetic transition, while the x=0.045 and 0.167 samples are two very different magnetic glasses. Thermal relaxation times are more than five times longer for x=0.167 than for x=0.045. In addition, the more concentrated glass shows history dependence and metastability upon field cooling
Universal scaling behavior at the upper critical dimension of non-equilibrium continuous phase transitions
In this work we analyze the universal scaling functions and the critical
exponents at the upper critical dimension of a continuous phase transition. The
consideration of the universal scaling behavior yields a decisive check of the
value of the upper critical dimension. We apply our method to a non-equilibrium
continuous phase transition. But focusing on the equation of state of the phase
transition it is easy to extend our analysis to all equilibrium and
non-equilibrium phase transitions observed numerically or experimentally.Comment: 4 pages, 3 figure
Approximating the monomer-dimer constants through matrix permanent
The monomer-dimer model is fundamental in statistical mechanics. However, it
is #P-complete in computation, even for two dimensional problems. A
formulation in matrix permanent for the partition function of the monomer-dimer
model is proposed in this paper, by transforming the number of all matchings of
a bipartite graph into the number of perfect matchings of an extended bipartite
graph, which can be given by a matrix permanent. Sequential importance sampling
algorithm is applied to compute the permanents. For two-dimensional lattice
with periodic condition, we obtain , where the exact value is
. For three-dimensional lattice with periodic condition,
our numerical result is , {which agrees with the best known
bound .}Comment: 6 pages, 2 figure
An investigation of standard thermodynamic quantities as determined via models of nuclear multifragmentation
Both simple and sophisticated models are frequently used in an attempt to
understand how real nuclei breakup when subjected to large excitation energies,
a process known as nuclear multifragmentation. Many of these models assume
equilibriumthermodynamics and produce results often interpreted as evidence of
a phase transition. This work examines one class of models and employs standard
thermodynamical procedure to explore the possible existence and nature of a
phase transition. The role of various terms, e.g. Coulomb and surface energy,
is discussed.Comment: 19 two-column format pages with 24 figure
Quality of DNA Extracted from Mouthwashes
Background
A cost effective, safe and efficient method of obtaining DNA samples is essential in large scale genetic analyses. Buccal cells are an attractive source of DNA, as their collection is non-invasive and can be carried out by mail. However, little attention has been given to the quality of DNA extracted from mouthwashes.
Methodology
Mouthwash-derived DNA was extracted from 500 subjects participating in a genetic study of high myopia. DNA quality was investigated using two standard techniques: agarose gel electrophoresis and quantitative polymerase chain reaction (qPCR).
Principal Findings
Whereas the majority of mouthwash-derived DNA samples showed a single band of high molecular weight DNA by gel electrophoresis, 8.9% (95% CI: 7.1–10.7%) of samples contained only a smear of low-to-medium molecular weight, degraded DNA. The odds of DNA degradation in a subject's second mouthwash sample, given degradation of the first, was significantly greater than one (OR = 3.13; 95% CI: 1.22–7.39; Fisher's test P = 0.009), suggesting that DNA degradation was at least partially a subject-specific phenomenon. Approximately 12.4% (95% CI: 10.4–14.4%) of mouthwash-derived DNA failed to PCR amplify efficiently (using an ~200 bp microsatellite marker). However, we found there was no significant difference in amplification success rate between DNA samples judged to be degraded or non-degraded by gel electrophoresis (Fisher's test P = 0.5).
Conclusions
This study demonstrated that DNA degradation affects a significant minority of saline mouthwashes, and that the phenomenon is partially subject-specific. Whilst the level of degradation did not significantly prevent successful amplification of short PCR fragments, previous studies suggest that such DNA degradation would compromise more demanding applications
Quantitative bioluminescence tomography using spectral derivative data
Bioluminescence imaging (BLI) is a non-contact, optical imaging technique based
on measurement of emitted light due to an internal source, which is then often directly related
to cellular activity. It is widely used in pre-clinical small animal imaging studies to assess the
progression of diseases such as cancer, aiding in the development of new treatments and
therapies. For many applications, the quantitative assessment of accurate cellular activity and
spatial distribution is desirable as it would enable direct monitoring for prognostic evaluation.
This requires quantitative spatially-resolved measurements of bioluminescence source
strength inside the animal to be obtained from BLI images. This is the goal of
bioluminescence tomography (BLT) in which a model of light propagation through tissue is
combined with an optimization algorithm to reconstruct a map of the underlying source
distribution. As most models consider only the propagation of light from internal sources to
the animal skin surface, an additional challenge is accounting for the light propagation from
the skin to the optical detector (e.g. camera). Existing approaches typically use a model of the
imaging system optics (e.g. ray-tracing, analytical optical models) or approximate corrections
derived from calibration measurements. However, these approaches are typically
computationally intensive or of limited accuracy. In this work, a new approach is presented in
which, rather than directly using BLI images acquired at several wavelengths, the spectral
derivative of that data (difference of BLI images at adjacent wavelengths) is used in BLT. As
light at similar wavelengths encounters a near-identical system response (path through the
optics etc.) this eliminates the need for additional corrections or system models. This
approach is applied to BLT with simulated and experimental phantom data and shown that the
error in reconstructed source intensity is reduced from 49% to 4%. Qualitatively, the accuracy
of source localization is improved in both simulated and experimental data, as compared to
reconstruction using the standard approach. The outlined algorithm can widely be adapted to
all commercial systems without any further technological modifications
The liquid to vapor phase transition in excited nuclei
For many years it has been speculated that excited nuclei would undergo a
liquid to vapor phase transition. For even longer, it has been known that
clusterization in a vapor carries direct information on the liquid- vapor
equilibrium according to Fisher's droplet model. Now the thermal component of
the 8 GeV/c pion + 197Au multifragmentation data of the ISiS Collaboration is
shown to follow the scaling predicted by Fisher's model, thus providing the
strongest evidence yet of the liquid to vapor phase transition.Comment: four pages, four figures, first two in color (corrected typo in Ref.
[26], corrected error in Fig. 4
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