943 research outputs found
Identification of blood-based molecular signatures for prediction of response and relapse in schizophrenia patients
- Author
- Publication venue
- Nature Publishing Group
- Publication date
- 01/01/2012
- Field of study
The current inability of psychiatric medicine to objectively select the most appropriate treatment or to predict imminent relapse are major factors contributing to the severity and clinical burden of schizophrenia. We have previously used multiplexed immunoassays to show that schizophrenia patients have a distinctive molecular signature in serum compared with healthy control subjects. In the present study, we used the same approach to measure biomarkers in a population of 77 schizophrenia patients who were followed up over 25 months with four aims: (1) to identify molecules associated with symptom severity in antipsychotic naive and unmedicated patients, (2) to determine biomarker signatures that could predict response over a 6-week treatment period, (3) to identify molecular panels that could predict the time to relapse in a cross-sectional population of patients in remission and (4) to investigate how the biological relapse signature changed throughout the treatment course. This led to identification of molecular signatures that could predict symptom improvement over the first 6 weeks of treatment as well as predict time to relapse in a subset of 18 patients who experienced recurrence of symptoms. This study provides the groundwork for the development of novel objective clinical tests that can help psychiatrists in the clinical management of schizophrenia
General practitioners’ perspectives on campaigns to promote rapid help-seeking behaviour at the onset of rheumatoid arthritis
- Author
- Allaart CF
- American College of Rheumatology
- Chan KWA
- Chris Deighton
- Christian D. Mallen
- Gerlag DM
- Grilli R
- Guest GS
- Hernandez-Carcia C
- Humphreys JH
- Karim Raza
- Kiely P
- McCormick A
- National Audit Office
- Nell VP
- NVivo qualitative data analysis software
- Oliver S
- Patrick Kiely
- Raza K
- Rebecca J. Stack
- Robinson PC
- Rodriguez-Polanco E
- Scott DL
- Sheppard J
- Smolen JS
- Squires D
- Thomson S
- Van der Linden MP
- Villeneuve E
- Wakefield MA
- Zara Llewellyn
- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/01/2014
- Field of study
Objective. To explore general practitioners’ (GPs’ ) perspectives on public health campaigns to encourage people with the early symptoms of rheumatoid arthritis (RA) to seek medical help rapidly. Design. Nineteen GPs participated in four semistructured focus groups. Focus groups were audio-recorded, transcribed verbatim, and analysed using thematic analysis. Results. GPs recognised the need for the early treatment of RA and identified that facilitating appropriate access to care was important. However, not all held the view that a delay in help seeking was a clinically significant issue. Furthermore, many were concerned that the early symptoms of RA were often non-specific, and that current knowledge about the nature of symptoms at disease onset was inadequate to inform the content of a help-seeking campaign. They argued that a campaign might not be able to specifically target those who need to present urgently. Poorly designed campaigns were suggested to have a negative impact on GPs’ workloads, and would “clog up” the referral pathway for genuine cases of RA. Conclusions. GPs were supportive of strategies to improve access to Rheumatological care and increase public awareness of RA symptoms. However, they have identified important issues that need to be considered in developing a public health campaign that forms part of an overall strategy to reduce time to treatment for patients with new onset RA. This study highlights the value of gaining GPs’ perspectives before launching health promotion campaigns
"After my husband's circumcision, I know that I am safe from diseases": Women's Attitudes and Risk Perceptions Towards Male Circumcision in Iringa, Tanzania.
- Author
- A Herman-Roloff
- B Auvert
- BA Friedland
- Caitlin E. Kennedy
- Catherine Shembilu
- CL Mattson
- D William Cameron
- Erica H. Layer
- G Guest
- G Kigozi
- HA Weiss
- HR Mahler
- J Dushoff
- JM Morse
- K Charmaz
- K Lundsby
- L Eaton
- LA Eaton
- Lilian Mgeni
- M Plotkin
- M Sandelowski
- M Westercamp
- MJ Wawer
- MM Cassell
- N Andersson
- N Fielding
- N Larke
- PC Hewett
- R Gray
- RA Alsallaq
- RC Bailey
- RC Bailey
- RH Gray
- RH Gray
- Romani B. Momburi
- S Kalichman
- Sarah W. Beckham
- SM Maregesi
- TB Hallett
- TB Hallett
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2013
- Field of study
While male circumcision reduces the risk of female-to-male HIV transmission and certain sexually transmitted infections (STIs), there is little evidence that circumcision provides women with direct protection against HIV. This study used qualitative methods to assess women's perceptions of male circumcision in Iringa, Tanzania. Women in this study had strong preferences for circumcised men because of the low risk perception of HIV with circumcised men, social norms favoring circumcised men, and perceived increased sexual desirability of circumcised men. The health benefits of male circumcision were generally overstated; many respondents falsely believed that women are also directly protected against HIV and that the risk of all STIs is greatly reduced or eliminated in circumcised men. Efforts to engage women about the risks and limitations of male circumcision, in addition to the benefits, should be expanded so that women can accurately assess their risk of HIV or STIs during sexual intercourse with circumcised men
A mathematical and computational review of Hartree-Fock SCF methods in Quantum Chemistry
- Author
- Abramowitzand M
- Adams TR
- Ahlrichs R
- Almlöf J
- Baldoni HA
- Bally T
- Barden CJ
- Barnes J
- Beachy M
- Binkley JS
- Binkley JS
- Bonneau R
- Bordner AJ
- Born M
- Born M
- Bowler DR
- Boys SF
- Brailsford DF
- Brooks BR
- Bryngelson JD
- Bryngelson JD
- Burant JC
- Burant JC
- Carbo R
- Challacombe M
- Clark T
- Cohen-Tannoudji C
- Cook DB
- Cramer CJ
- Császár AG
- Cullum JK
- Dill KA
- Dirac PAM
- Ditchfield R
- Dobson CM
- Dunning TH
- Dyczmons V
- Echenique P
- Echenique P
- Echenique P
- Elstner M
- Ericsson T
- Fock V
- Frey RF
- Friesecke G
- Friesner RA
- Frisch MJ
- Füsti-Molnár L
- Füsti-Molnár L
- Gill PMW
- Gill PMW
- Gill PMW
- Gill PMW
- Gill PMW
- Ginalski K
- Greengard L
- Guest MF
- Hall GG
- Hao M-H
- Hariharan PC
- Hartree DR
- Head-Gordon M
- Head-Gordon M
- Hehre WJ
- Hehre WJ
- Helgaker T
- Hirao K
- Hratchian HP
- Hunter G
- Hunziger W
- Hunziker W
- Hurley AC
- Häser M
- Izmaylov AF
- J. L. Alonso
- Jensen F
- Jensen F
- Jensen F
- Jiancheng X
- Jorgensen WL
- Kato T
- Kirkpatrick S
- Kobus J
- Kohn W
- Koopmans T
- Krishnan R
- Kutteh R
- Lambrecht DS
- Levine IN
- Liang W
- Lieb EH
- Lieb EH
- Lions PL
- Láng A
- MacKerell AR
- Marder MP
- Marinari E
- Maslen PE
- Mathar RJ
- Mauri F
- McMurchie LE
- McWeeny R
- Millam JM
- Morozov AV
- Morozov AV
- Obara S
- Ochsenfeld C
- Ochsenfeld C
- Ochsenfeld C
- Onuchic JN
- Ordejón P
- Pablo Echenique
- Panas I
- Parr RG
- Pearlman DA
- Perczel A
- Petersen HG
- Peterson M
- Plakhutin NN
- Plotkin SS
- Ponder JW
- Pople JA
- Pople JA
- Pople JA
- Pulay P
- Rodríguez AM
- Roothaan CCJ
- Roothaan CCJ
- Ruskai MB
- Salek P
- Schlegel HB
- Schlegel HB
- Schlegel HB
- Schlegel HB
- Schueler-Furman O
- Schwegler E
- Scuseria GE
- Seeger R
- Shao Y
- Shao Y
- Shao Y
- Shida T
- Shull H
- Simon B
- Simons J
- Skolnick L
- Slater JC
- Slater JC
- Snow CD
- Spitznagel GW
- Stewart JJP
- Stewart JJP
- Strain MC
- Strout DL
- Sutcliffe BT
- Sutcliffe BT
- Sutcliffe BT
- Szabo A
- Taylor BN
- Termath V
- Thørgensen L
- Vargas R
- White CA
- White CA
- Winter CVan
- Woodgate GK
- Young MA
- Yserentant H
- Yu C-H
- Zener C
- Zhislin GM
- Publication venue
- 'Informa UK Limited'
- Publication date
- 10/12/2007
- Field of study
We present here a review of the fundamental topics of Hartree-Fock theory in
Quantum Chemistry. From the molecular Hamiltonian, using and discussing the
Born-Oppenheimer approximation, we arrive to the Hartree and Hartree-Fock
equations for the electronic problem. Special emphasis is placed in the most
relevant mathematical aspects of the theoretical derivation of the final
equations, as well as in the results regarding the existence and uniqueness of
their solutions. All Hartree-Fock versions with different spin restrictions are
systematically extracted from the general case, thus providing a unifying
framework. Then, the discretization of the one-electron orbitals space is
reviewed and the Roothaan-Hall formalism introduced. This leads to a exposition
of the basic underlying concepts related to the construction and selection of
Gaussian basis sets, focusing in algorithmic efficiency issues. Finally, we
close the review with a section in which the most relevant modern developments
(specially those related to the design of linear-scaling methods) are commented
and linked to the issues discussed. The whole work is intentionally
introductory and rather self-contained, so that it may be useful for non
experts that aim to use quantum chemical methods in interdisciplinary
applications. Moreover, much material that is found scattered in the literature
has been put together here to facilitate comprehension and to serve as a handy
reference.Comment: 64 pages, 3 figures, tMPH2e.cls style file, doublesp, mathbbol and
subeqn package
Development of a blood-based molecular biomarker test for identification of schizophrenia before disease onset
- Author
- A Gonzalez-Pinto
- AB Niculescu
- AM Millikan
- BJ Miller
- D Ghosh
- DO Perkins
- E Domenici
- E Magaud
- E Magaud
- E Schwarz
- E Schwarz
- E Schwarz
- E Zarogianni
- J Ventura
- JM Pelayo-Teran
- JM Ramsey
- LW Harris
- M van der Gaag
- MK Chan
- N Muller
- N Muller
- P Fusar-Poli
- P Fusar-Poli
- PC Guest
- PM Bossuyt
- R Fluss
- R Tandon
- R Tibshirani
- S Bahn
- SM Kurian
- T Hastie
- T Sing
- TG van Erp
- V Barnett
- W Shi
- WE Johnson
- XY Sun
- Y Benjamini
- Y Li
- Y Li
- Y Takayanagi
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2015
- Field of study
Recent research efforts have progressively shifted towards preventative psychiatry and prognostic identification of individuals before disease onset. We describe the development of a serum biomarker test for the identification of individuals at risk of developing schizophrenia based on multiplex immunoassay profiling analysis of 957 serum samples. First, we conducted a meta-analysis of five independent cohorts of 127 first-onset drug-naive schizophrenia patients and 204 controls. Using least absolute shrinkage and selection operator regression, we identified an optimal panel of 26 biomarkers that best discriminated patients and controls. Next, we successfully validated this biomarker panel using two independent validation cohorts of 93 patients and 88 controls, which yielded an area under the curve (AUC) of 0.97 (0.95-1.00) for schizophrenia detection. Finally, we tested its predictive performance for identifying patients before onset of psychosis using two cohorts of 445 pre-onset or at-risk individuals. The predictive performance achieved by the panel was excellent for identifying USA military personnel (AUC: 0.90 (0.86-0.95)) and help-seeking prodromal individuals (AUC: 0.82 (0.71-0.93)) who developed schizophrenia up to 2 years after baseline sampling. The performance increased further using the latter cohort following the incorporation of CAARMS (Comprehensive Assessment of At-Risk Mental State) positive subscale symptom scores into the model (AUC: 0.90 (0.82-0.98)). The current findings may represent the first successful step towards a test that could address the clinical need for early intervention in psychiatry. Further developments of a combined molecular/symptom-based test will aid clinicians in the identification of vulnerable patients early in the disease process, allowing more effective therapeutic intervention before overt disease onset
Secretion of Fc-amidated peptide fusion proteins by Chinese hamster ovary cells
- Author
- AE Baker
- AS Kolhekar
- AS Kolhekar
- BA Eipper
- Betty A. Eipper
- C Gerald
- C Rajagopal
- DM Czajkowsky
- EE Chufan
- EJ Husten
- GD Ciccotosto
- Jiali Li
- KA Johnson
- KM Braas
- Kristina R. Carlson
- M Skulj
- M Tsubaki
- Michael Naso
- Omid Vafa
- PC Guest
- PJ Brighton
- PP Tamburini
- R Kulathila
- R Meskini El
- Richard E. Mains
- S Handa
- S Khan
- SL Milgram
- ST Prigge
- ST Prigge
- Steven C. Pomerantz
- T Kaschak
- TA Czyzyk
- William Strohl
- X Siebert
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Jet energy measurement with the ATLAS detector in proton-proton collisions at root s=7 TeV
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdesselam A
- Abdinov O
- Abi B
- Abolins M
- Abramowicz H
- Abreu H
- Acerbi E
- Acharya BS
- Adams DL
- Addy TN
- Adelman J
- Aderholz M
- Adomeit S
- Adragna P
- Adye T
- Aefsky S
- Aguilar-Saavedra JA
- Aharrouche M
- Ahlen SP
- Ahles F
- Ahmad A
- Ahsan M
- Aielli G
- Akdogana T
- Akesson TPA
- Akimoto G
- Akimov AV
- Akiyama A
- Aktas A
- Alam MA
- Alam MS
- Albert J
- Albrand S
- Aleksa M
- Aleksandrov IN
- Alessandria F
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Aliev M
- Alimonti G
- Alison J
- Aliyev M
- Allport PP
- Allwood-Spiers SE
- Almenar CC
- Almond J
- Aloisio A
- Alon R
- Alonso A
- Alviggi MG
- Amako K
- Amaral P
- Amelung C
- Ammosov VV
- Amorim A
- Amoros G
- Amram N
- Anastopoulos C
- Ancu LS
- Andari N
- Andeen T
- Anders CF
- Anders G
- Anderson KJ
- Andreazza A
- Andrei V
- Andrieux M-L
- Anduaga XS
- Angerami A
- Anghinolfi F
- Anh TV
- Anjos N
- Annovi A
- Antonaki A
- Antonelli M
- Antonov A
- Antos J
- Anulli F
- Aoun S
- Apolle R
- Arabidze G
- Aracena I
- Arai Y
- Aranda CP
- Arce ATH
- Archambault JP
- Arfaoui S
- Arguin J-F
- Arik E
- Arik M
- Armbruster AJ
- Arnaez O
- Arnault C
- Artamonov A
- Artoni G
- Arutinov D
- Asai S
- Asfandiyarov R
- Ask S
- Asman B
- Asner D
- Asquith L
- Assamagan K
- Astbury A
- Astvatsatourov A
- Atoian G
- Aubert B
- Auge E
- Augsten K
- Aurousseau M
- Austin N
- Avolio G
- Avramidou R
- Axen D
- Ay C
- Azuelos G
- Azuma Y
- Baak MA
- Baccaglioni G
- Bacci C
- Bach AM
- Bachacou H
- Bachas K
- Bachy G
- Backes M
- Backhaus M
- Badescu E
- Bagnaia P
- Bahinipati S
- Bai Y
- Bailey DC
- Bain T
- Baines JT
- Baker MD
- Baker OK
- Baker S
- Banas E
- Banerjee P
- Banerjee S
- Banfi D
- Bangert A
- Bansal V
- Bansil HS
- Barajas CAC
- Barak L
- Baranov SP
- Barashkou A
- Barber T
- Barberio EL
- Barberis D
- Barbero M
- Bardin DY
- Barillari T
- Barisonzi M
- Barklow T
- Barlow N
- Barnett BM
- Barnett RM
- Baroncelli A
- Barone G
- Barr AJ
- Barreiro F
- Barrera CO
- Barrillon P
- Bartoldus R
- Barton AE
- Bartsch D
- Bartsch V
- Bates RL
- Batkova L
- Batley JR
- Battaglia A
- Battistin M
- Battistoni G
- Bauer F
- Bawa HS
- Beare B
- Beau T
- Beauchemin PH
- Beccherle R
- Bechtle P
- Beck GA
- Beck HP
- Beckingham M
- Becks KH
- Beddall A
- Beddall AJ
- Bedikian S
- Bednyakov VA
- Bee CP
- Begel M
- Behera PK
- Beimforde M
- Belanger-Champagne C
- Belenguer MJ
- Bell PJ
- Bell WH
- Bella G
- Bella LA
- Bellagamba L
- Bellina F
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- Beloborodova O
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- Beltramello O
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- Benary O
- Benchekroun D
- Benchouk C
- Bendel M
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- Benjamin DP
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- Bieniek SP
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- Bobbink GJ
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- Bocci A
- Boddy CR
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- Borisov A
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- Borjanovic I
- Borroni S
- Bos K
- Boscherini D
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- Boterenbrood H
- Botterill D
- Bouchami J
- Boudreau J
- Bouhova-Thacker EV
- Bourdarios C
- Bousson N
- Boveia A
- Boyd J
- Boyko IR
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- Bozovic-Jelisavcic I
- Bracinik J
- Braem A
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- Brandenburg GW
- Brandt A
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- Brandt O
- Bratzler U
- Brau B
- Brau JE
- Braun HM
- Brelier B
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- Brodbeck TJ
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- Butterworth JM
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- Castanheira MTD
- Castillo LRF
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- Charlton DG
- Chavda V
- Cheatham S
- Chekanov S
- Chekulaev SV
- Chelkov GA
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- Cheong ALF
- Cheplakov A
- Chepurnov VF
- Chernyatin V
- Cheu E
- Cheung SL
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- Chiefari G
- Chikovani L
- Childers JT
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- Chiodini G
- Chizhov MV
- Choudalakis G
- Chouridou S
- Christidi IA
- Christov A
- Chromek-Burckhart D
- Chu ML
- Chudoba J
- Ciapetti G
- Ciba K
- Ciftci AK
- Ciftci R
- Cinca D
- Cindro V
- Ciobotaru MD
- Cioccaa C
- Ciocio A
- Cirilli M
- Citterio M
- Ciubancan M
- Clark A
- Clark PJ
- Cleland W
- Clemens JC
- Clement B
- Clement C
- Clifft RW
- Coadou Y
- Cobal M
- Coccaro A
- Cochran J
- Codina EP
- Coe P
- Cogan JG
- Coggeshall J
- Cogneras E
- Cojocaru CD
- Colas J
- Colijn AP
- Collaboration ATLAS
- Collard C
- Collins NJ
- Collins-Tooth C
- Collot J
- Colon G
- Coniavitis E
- Conidi MC
- Consonni M
- Consorti V
- Constantinescu S
- Conta C
- Conventi F
- Cook J
- Cooke M
- Cooper BD
- Cooper-Sarkar AM
- Copic K
- Cornelissen T
- Corradi M
- Correia AMH
- Corriveau F
- Corso-Radu A
- Cortes-Gonzalez A
- Cortiana G
- Costa G
- Costa MJ
- Costanzo D
- Costin T
- Cote D
- Courneyea L
- Cowan G
- Cowden C
- Cox BE
- Cranmer K
- Cranshaw J
- Crepe-Renaudin S
- Crescioli F
- Cristinziani M
- Crosetti G
- Crupi R
- Cuciuc C-M
- Curatolo M
- Curtis CJ
- Curull XE
- Cwetanski P
- Czirr H
- Czyczula Z
- D'Auria S
- D'Onofrio M
- D'Orazio A
- Da Costa JBG
- Da Costa JGPF
- Da Silva PVM
- Da Via C
- Dabrowski W
- Dai T
- Dallapiccola C
- Daly CH
- Dam M
- Damazio DO
- Dameri M
- Damiani DS
- Danielsson HO
- Dannheim D
- Dao V
- Darbo G
- Darlea GL
- Daum C
- Dauvergne JP
- Davey W
- Davidek T
- Davidson N
- Davidson R
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- Davison AR
- Davygora Y
- Dawe E
- Dawson I
- Dawson JW
- Daya-Ishmukhametova RK
- de Asmundis R
- De Castro S
- De Cecco S
- De Graat J
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- De Jong P
- De la Hoz SG
- De la Taille C
- De la Torre H
- De Lima JGR
- De Lotto B
- De Mora L
- De Nooij L
- De Pedis D
- De Regie JBDV
- De Renstrom PAB
- De Salvo A
- De Sanctis U
- De Santo A
- De K
- Dean S
- Debbe R
- Dedovich DV
- Degenhardt J
- Dehchar M
- Del Papa C
- Del Peso J
- Del Prete T
- Deliyergiyev M
- Dell'Acqua A
- Dell'Asta L
- Della Pietra M
- Della Porta GZ
- della Volpe D
- Delmastro M
- Delpierre P
- Delruelle N
- Delsart PA
- Deluca C
- Demers S
- Demichev M
- Demirkoz B
- Deng J
- Deng W
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- Smizanska M
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- Takahashi Y
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- Torchiani I
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- Tyrvainen H
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- Uhrmacher M
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- Underwood DG
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- Varnes EW
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- Vorobel V
- Vorobiev AP
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- Vossebeld JH
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- Vukotic I
- Wagner P
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- Yagci KD
- Yamada M
- Yamaguchi H
- Yamamoto A
- Yamamoto K
- Yamamoto S
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- Yamanaka T
- Yamaoka J
- Yamazaki T
- Yamazaki Y
- Yan Z
- Yang H
- Yang UK
- Yang Y
- Yang Y
- Yang Z
- Yanush S
- Yao Y
- Yasu Y
- Ye J
- Ye S
- Yildizb HD
- Yilmaz M
- Yoosootiniya R
- Yorita K
- Yoshida R
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- Youssef S
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- Yu J
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- Yurkewicz A
- Zaets VG
- Zaidan R
- Zaitsev AM
- Zajacova Z
- Zalite YK
- Zanello L
- Zarzhitsky P
- Zaytsev A
- Zeitnitz C
- Zeller M
- Zeman M
- Zemla A
- Zendler C
- Zenin O
- Zenonos Z
- Zenz S
- Zerwas D
- Zhan Z
- Zhang D
- Zhang H
- Zhang J
- Zhang Q
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- Zhao L
- Zhao T
- Zhao Z
- Zhemchugov A
- Zheng S
- Zhong J
- Zhou B
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- Zhuravlov V
- Zieminska D
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- Zimmermann S
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zitoun R
- Zivkovic L
- Zmouchko VV
- Zobernig G
- Zoccoli A
- Zolnierowski Y
- Zsenei A
- Zutshi V
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/03/2013
- Field of study
The jet energy scale and its systematic uncertainty are determined for jets measured with the ATLAS detector at the LHC in proton-proton collision data at a centre-of-mass energy of √s = 7TeV corresponding to an integrated luminosity of 38 pb-1. Jets are reconstructed with the anti-kt algorithm with distance parameters R=0. 4 or R=0. 6. Jet energy and angle corrections are determined from Monte Carlo simulations to calibrate jets with transverse momenta pT≥20 GeV and pseudorapidities {pipe}η{pipe}<4. 5. The jet energy systematic uncertainty is estimated using the single isolated hadron response measured in situ and in test-beams, exploiting the transverse momentum balance between central and forward jets in events with dijet topologies and studying systematic variations in Monte Carlo simulations. The jet energy uncertainty is less than 2. 5 % in the central calorimeter region ({pipe}η{pipe}<0. 8) for jets with 60≤pT<800 GeV, and is maximally 14 % for pT<30 GeV in the most forward region 3. 2≤{pipe}η{pipe}<4. 5. The jet energy is validated for jet transverse momenta up to 1 TeV to the level of a few percent using several in situ techniques by comparing a well-known reference such as the recoiling photon pT, the sum of the transverse momenta of tracks associated to the jet, or a system of low-pT jets recoiling against a high-pT jet. More sophisticated jet calibration schemes are presented based on calorimeter cell energy density weighting or hadronic properties of jets, aiming for an improved jet energy resolution and a reduced flavour dependence of the jet response. The systematic uncertainty of the jet energy determined from a combination of in situ techniques is consistent with the one derived from single hadron response measurements over a wide kinematic range. The nominal corrections and uncertainties are derived for isolated jets in an inclusive sample of high-pT jets. Special cases such as event topologies with close-by jets, or selections of samples with an enhanced content of jets originating from light quarks, heavy quarks or gluons are also discussed and the corresponding uncertainties are determined. © 2013 CERN for the benefit of the ATLAS collaboration
Measurement of the cross-section of high transverse momentum vector bosons reconstructed as single jets and studies of jet substructure in pp collisions at √s = 7 TeV with the ATLAS detector
- Author
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- Abajyan T
- Abbott B
- Abdallah J
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- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2014
- Field of study
This paper presents a measurement of the cross-section for high transverse momentum W and Z bosons produced in pp collisions and decaying to all-hadronic final states. The data used in the analysis were recorded by the ATLAS detector at the CERN Large Hadron Collider at a centre-of-mass energy of √s = 7 TeV;{\rm Te}{\rm V}andcorrespondtoanintegratedluminosityof4.6\;{\rm f}{{{\rm b}}^{-1}}.ThemeasurementisperformedbyreconstructingtheboostedWorZbosonsinsinglejets.ThereconstructedjetmassisusedtoidentifytheWandZbosons,andajetsubstructuremethodbasedonenergyclusterinformationinthejetcentre−of−massframeisusedtosuppressthelargemulti−jetbackground.Thecross−sectionforeventswithahadronicallydecayingWorZboson,withtransversemomentum{{p}_{{\rm T}}}\gt 320\;{\rm Ge}{\rm V}andpseudorapidity|\eta |\lt 1.9,ismeasuredtobe{{\sigma }_{W+Z}}=8.5\pm 1.7$ pb and is compared to next-to-leading-order calculations. The selected events are further used to study jet grooming techniques
Observation of associated near-side and away-side long-range correlations in √sNN=5.02 TeV proton-lead collisions with the ATLAS detector
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- Zevi Della Porta G
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- Zhemchugov A
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- Zitoun R
- Zivković L
- Zmouchko VV
- Zobernig G
- Zoccoli A
- Zur Nedden M
- Zutshi V
- Zwalinski L
- Publication venue
- American Physical Society
- Publication date
- 01/01/2012
- Field of study
Two-particle correlations in relative azimuthal angle (Δϕ) and pseudorapidity (Δη) are measured in √sNN=5.02 TeV p+Pb collisions using the ATLAS detector at the LHC. The measurements are performed using approximately 1 μb-1 of data as a function of transverse momentum (pT) and the transverse energy (ΣETPb) summed over 3.1<η<4.9 in the direction of the Pb beam. The correlation function, constructed from charged particles, exhibits a long-range (2<|Δη|<5) “near-side” (Δϕ∼0) correlation that grows rapidly with increasing ΣETPb. A long-range “away-side” (Δϕ∼π) correlation, obtained by subtracting the expected contributions from recoiling dijets and other sources estimated using events with small ΣETPb, is found to match the near-side correlation in magnitude, shape (in Δη and Δϕ) and ΣETPb dependence. The resultant Δϕ correlation is approximately symmetric about π/2, and is consistent with a dominant cos2Δϕ modulation for all ΣETPb ranges and particle pT
Search for pair-produced long-lived neutral particles decaying to jets in the ATLAS hadronic calorimeter in ppcollisions at √s=8TeV
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- Youssef S
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- Zaidan R
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- Zanzi D
- Zeitnitz C
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- Zemla A
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- Zhemchugov A
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- Zibell A
- Zieminska D
- Zimine NI
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- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2014
- Field of study
The ATLAS detector at the Large Hadron Collider at CERN is used to search for the decay of a scalar boson to a pair of long-lived particles, neutral under the Standard Model gauge group, in 20.3fb−1of data collected in proton–proton collisions at √s=8TeV. This search is sensitive to long-lived particles that decay to Standard Model particles producing jets at the outer edge of the ATLAS electromagnetic calorimeter or inside the hadronic calorimeter. No significant excess of events is observed. Limits are reported on the product of the scalar boson production cross section times branching ratio into long-lived neutral particles as a function of the proper lifetime of the particles. Limits are reported for boson masses from 100 GeVto 900 GeV, and a long-lived neutral particle mass from 10 GeVto 150 GeV
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