Unsupervised Cross-lingual Image Captioning

Most recent image captioning works are conducted in English as the majority of image-caption datasets are in English. However, there are a large amount of non-native English speakers worldwide. Generating image captions in different languages is worth exploring. In this paper, we present a novel unsupervised method to generate image captions without using any caption corpus. Our method relies on 1) a cross-lingual auto-encoding, which learns the scene graph mapping function along with the scene graph encoders and sentence decoders on machine translation parallel corpora, and 2) an unsupervised feature mapping, which seeks to map the encoded scene graph features from image modality to sentence modality. By leveraging cross-lingual auto-encoding, cross-modal feature mapping, and adversarial learning, our method can learn an image captioner to generate captions in different languages. We verify the effectiveness of our proposed method on the Chinese image caption generation. The comparisons against several baseline methods demonstrate the effectiveness of our approach.Comment: 8 page

Membrane Contact Demulsification: A Superhydrophobic ZIF-8@rGO Membrane for Water-in-Oil Emulsion Separation

Achieving a water–oil interface imbalance has been identified as a critical factor in the demulsification of water-in-oil emulsions. However, conventional demulsifying membranes generally break the interface balance by depending on a relatively high transmembrane pressure. Here, we present a “contact demulsification” concept to naturally and quickly achieve disruption of the water–oil interface balance. For this purpose, a novel demulsifying membrane with a high flux of the organic component has been developed via the simple vacuum assembly of zeolitic imidazolate framework-8 (ZIF-8)@reduced graphene oxide (rGO) microspheres (ZGS) on a polytetrafluoroethylene (PTFE) support, followed by immobilization processing in a polydimethylsiloxane (PDMS) crosslinking solution. Due to the micro-nano hierarchies of the ZGS, the prepared ZIF-8@rGO@PDMS/PTFE (ZGPP) membranes feature a unique superhydrophobic surface, which results in a water–oil interface imbalance when a surfactant-stabilized water-in-oil emulsion comes into contact with the membrane surface. Under a low transmembrane pressure of 0.15 bar (15 kPa), such membranes show an excellent separation efficiency (∼99.57%) and a high flux of 2254 L·m−2·h−1, even for surfactant-stabilized nanoscale water-in-toluene emulsions (with an average droplet size of 57 nm). This “contact demulsification” concept paves the way for developing next-generation demulsifying membranes for water-in-oil emulsion separation

Electrospun chitosan-graft-poly (ɛ-caprolactone)/poly (ɛ-caprolactone) nanofibrous scaffolds for retinal tissue engineering

A promising therapy for retinal diseases is to employ biodegradable scaffolds to deliver retinal progenitor cells (RPCs) for repairing damaged or diseased retinal tissue. In the present study, cationic chitosan-graft-poly(ɛ-caprolactone)/polycaprolactone (CS-PCL/PCL) hybrid scaffolds were successfully prepared by electrospinning. Characterization of the obtained nanofibrous scaffolds indicated that zeta-potential, fiber diameter, and the content of amino groups on their surface were closely correlated with the amount of CS-PCL in CS-PCL/PCL scaffolds. To assess the cell–scaffold interaction, mice RPCs (mRPCs) were cultured on the electrospun scaffolds for 7 days. In-vitro proliferation assays revealed that mRPCs proliferated faster on the CS-PCL/PCL (20/80) scaffolds than the other electrospun scaffolds. Scanning electron microscopy and the real-time quantitative polymerase chain reaction results showed that mRPCs grown on CS-PCL/PCL (20/80) scaffolds were more likely to differentiate towards retinal neurons than those on PCL scaffolds. Taken together, these results suggest that CS-PCL/PCL(20/80) scaffolds have potential application in retinal tissue engineering

Prominent Size Effects without a Depolarization Field Observed in Ultrathin Ferroelectric Oxide Membranes

The increasing miniaturization of electronics requires a better understanding of material properties at the nanoscale. Many studies have shown that there is a ferroelectric size limit in oxides, below which the ferroelectricity will be strongly suppressed due to the depolarization field, and whether such a limit still exists in the absence of the depolarization field remains unclear. Here, by applying uniaxial strain, we obtain pure in-plane polarized ferroelectricity in ultrathin SrTiO3 membranes, providing a clean system with high tunability to explore ferroelectric size effects especially the thickness-dependent ferroelectric instability with no depolarization field. Surprisingly, the domain size, ferroelectric transition temperature, and critical strain for room-temperature ferroelectricity all exhibit significant thickness dependence. These results indicate that the stability of ferroelectricity is suppressed (enhanced) by increasing the surface or bulk ratio (strain), which can be explained by considering the thickness-dependent dipole-dipole interactions within the transverse Ising model. Our study provides new insights into ferroelectric size effects and sheds light on the applications of ferroelectric thin films in nanoelectronics

Quad-Band NGD Investigation on Crossed Resonator Interconnect Structure

This brief explains why the coupling between crossed interconnect structure and straight I-lines of printed circuit board (PCB) presents bandpass (BP) negative group delay (NGD) behavior. The NGD effect is investigated with crossed resonator innovative microstrip equivalent topology. As proof of concept (POC), the influences of crossed resonator circuit physical variables on the BP-NGD behavior are illustrated by parametric study. The cross-coupled microstrip circuit POC BP-NGD responses is validated with quad-band NGD behavior. A very good agreement between calculations, simulations and experimentations state results of NGD center frequency-NGD value, (1.541-GHz, −1.84-ns), (2.397-GHz, −1.6-ns), (3.379-GHz, −1.38-ns), and (4.164-GHz, −0.91-ns) representing the 1st, 2nd, 3rd and 4th NGD band, respectively. The studied design has notable advantages in term of NGD application integration in the multi-band transceiver system simplicity and size reduction

Photon upconversion through triplet exciton-mediated energy relay.

Exploration of upconversion luminescence from lanthanide emitters through energy migration has profound implications for fundamental research and technology development. However, energy migration-mediated upconversion requires stringent experimental conditions, such as high power excitation and special migratory ions in the host lattice, imposing selection constraints on lanthanide emitters. Here we demonstrate photon upconversion of diverse lanthanide emitters by harnessing triplet exciton-mediated energy relay. Compared with gadolinium-based systems, this energy relay is less dependent on excitation power and enhances the emission intensity of Tb3+ by 158-fold. Mechanistic investigations reveal that emission enhancement is attributable to strong coupling between lanthanides and surface molecules, which enables fast triplet generation (<100 ps) and subsequent near-unity triplet transfer efficiency from surface ligands to lanthanides. Moreover, the energy relay approach supports long-distance energy transfer and allows upconversion modulation in microstructures. These findings enhance fundamental understanding of energy transfer at molecule-nanoparticle interfaces and open exciting avenues for developing hybrid, high-performance optical materials

Development of an Incentive Model for General Practitioners in Fengxian District of Shanghai Based on Herzberg's Motivation-hygiene Theory

BackgroundIn view of the shortage of general practitioners (GPs) and limited community healthcare resources, it is urgently necessary for community health institutions to find accurate and scientific incentive methods to retain GPs and help them to realize their full potential, as well as promote the development of both community health institutions and GPs, thereby benefiting the health promotion of community residents.ObjectiveTo develop an incentive model for GPs to test the performance and effectiveness of current incentives for GPs, so as to put forward suggestions to improve the mechanisms of employing and retaining GPs.MethodsIn August 2019, we recruited 204 GPs from 11 community health centers (CHCs) in Shanghai&apos;s Fengxian District using stratified random sampling to attend an online survey using a questionnaire named General Practitioners&apos; Perception and Evaluation of Incentive Measures developed based on our previous research results and Herzberg&apos;s motivation-hygiene theory. Then from August to September 2019, we invited directors responsible for medical care or public health issues, and medical quality control department heads from the above-mentioned 11 CHCs to attend an online survey using a questionnaire named Workload for General Practitioners in Community Health Centers of Fengxian District developed by usbased on a literature review. Then under the guidance of Herzberg&apos;s motivation-hygiene theory, we constructed a structural equation to develop an incentive model for GPs within Fengxian District with representative incentive policies, systems and initiatives related to GPs selected from the survey results as latent independent variables to measure GPs&apos; (responders&apos;) perception and assessment of incentives, and with willingness to work, service radius, and workload of GPs as dependent variables.ResultsThe average scores for the implementation of incentive measures, and its associated influence on GPs&apos; work status assessed by the 204 GPs were (0.77±0.14) , and (0.73±0.19) , respectively. The assessment score for implementation of incentive measures for GPs differed significantly by personal health condition and administrative position in the respondents (P&lt;0.05) . The assessment score for the influence of implementing incentive measures on GPs&apos; work status differed significantly by personal health condition in the respondents (P&lt;0.05) . Spearman correlation analysis showed that GPs&apos; work status was associated with the implementation of 25 incentive measures (one incentive measure at the subdistrict level was not included for analysis) (P&lt;0.05) . The top three most highly correlated incentive measures were performance distribution (rs=0.652) , performance-based salary calculation (rs=0.621) , and wages and benefits (rs=0.614) . Partial correlation analysis indicated that, after controlling for variables such as the regional policy environment, the street and town government, and the work unit, the assessment score for implementation of either regional, or subdistrict or institutional incentive measures for GPs, was positively correlated with the assessment score for the influence of implementation of incentive measures for GPs on GPs&apos; work status (r=0.381, 0.387, 0.528, P&lt;0.001) . Theaverage assessment score for willingness to work by the respondents was (0.76±0.18) points. Theassessment scores of willingness to work by the respondents differed significantly by work unit (P&lt;0.05) . Structural equation modeling revealed that the implementation of policy incentive measures influenced GPs&apos; workload via GPs&apos; willingness to work. Specifically, the implementation of policy incentive measures increased GPs&apos; willingness to work (w1=0.43) , while GPs&apos; willingness to work decreased with the increase of weighted workload (w2=-0.156) .ConclusionThe GPs in Fengxian District showed higher level of willingness to work, namely, relatively high job stability, but they had not been incentivized by policy incentives to be competitive in obtaining improved performance, indicating that although policy incentives have produced partial effects on incentivizing GPs, the effects are still unsatisfactory. In the long run, it is necessary to consider whether there will be changes in GPs&apos; retention status due to the lack of work initiative. For GPs, besides a guarantee of stable income, incentives to get more by doing more are also needed, which may be achieved by increasing the incentive authority and proportion of community health institutions when the total amount of incentives is limited

The crosstalk between anoikis and epithelial-mesenchymal transition and their synergistic roles in predicting prognosis in colon adenocarcinoma

Anoikis and epithelial-mesenchymal transition (EMT) are significant phenomena occurring in distant metastasis of colon adenocarcinoma (COAD). A comprehensive understanding of their crosstalk and the identification of key genes are vital for treating the distant metastasis of COAD. The objective of this study was to design and validate accurate prognostic predictors for COAD patients based on the anoikis and EMT processes. We obtained gene signatures from various databases and performed univariate and multivariate Cox regression analyses, principal component analysis (PCA). The COAD patients were categorized into the worst prognosis group, the Anoikis Potential Index (API) Low + EMT Potential Index (EPI) High group and the others group. Then we utilized gene set enrichment analysis (GSEA) to identify differentially expressed genes and to establish a prognostic risk model. The model classified patients into high- or low-risk groups, with patients in the high-risk group displaying worse survival status. A nomogram was established to predict overall survival rates, demonstrating high specificity and sensitivity. Additionally, we connected the risk model to the tumor microenvironment (TME) using single-sample GSEA and the MCP counter tool, as well as evaluated the sensitivity to common chemotherapeutic drugs, such as Gefitinib and Gemcitabine. Lastly, cell and tissue experiments suggested a positive correlation among anoikis resistance, EMT, and liver/lung metastasis of COAD. This is the first study to comprehensively analyze the crosstalk between anoikis and EMT and offers new therapeutic targets for COAD metastasis patients

Photon upconversion through triplet exciton-mediated energy relay

Funder: Innovation programme under the Marie Skłodowska-Curie grant agreement No 797619Funder: China Scholarship Council (CSC); doi: https://doi.org/10.13039/501100004543Funder: RCUK | Engineering and Physical Sciences Research Council (EPSRC); doi: https://doi.org/10.13039/501100000266Abstract: Exploration of upconversion luminescence from lanthanide emitters through energy migration has profound implications for fundamental research and technology development. However, energy migration-mediated upconversion requires stringent experimental conditions, such as high power excitation and special migratory ions in the host lattice, imposing selection constraints on lanthanide emitters. Here we demonstrate photon upconversion of diverse lanthanide emitters by harnessing triplet exciton-mediated energy relay. Compared with gadolinium-based systems, this energy relay is less dependent on excitation power and enhances the emission intensity of Tb3+ by 158-fold. Mechanistic investigations reveal that emission enhancement is attributable to strong coupling between lanthanides and surface molecules, which enables fast triplet generation (<100 ps) and subsequent near-unity triplet transfer efficiency from surface ligands to lanthanides. Moreover, the energy relay approach supports long-distance energy transfer and allows upconversion modulation in microstructures. These findings enhance fundamental understanding of energy transfer at molecule-nanoparticle interfaces and open exciting avenues for developing hybrid, high-performance optical materials

Corrigendum to: The TianQin project: current progress on science and technology

In the originally published version, this manuscript included an error related to indicating the corresponding author within the author list. This has now been corrected online to reflect the fact that author Jun Luo is the corresponding author of the article