392 research outputs found
A high-sensitivity laser-pumped Mx magnetometer
Abstract.: We discuss the design and performance of a laser-pumped cesium vapor magnetometer in the Mx configuration. The device will be employed in the control and stabilization of fluctuating magnetic fields and gradients in a new experiment searching for a permanent electric dipole moment of the neutron. We have determined the intrinsic sensitivity of the device to be 15 fT in a 1 Hz bandwidth, limited by technical laser noise. In the shot noise limit the magnetometer can reach a sensitivity of 10 fT in a 1 Hz bandwidth. We have used the device to study the fluctuations of a stable magnetic field in a multi-layer magnetic shield for integration times in the range of 2-100 seconds. The residual fluctuations for times up to a few minutes are traced back to the instability of the power supply used to generate the fiel
Compactness for Holomorphic Supercurves
We study the compactness problem for moduli spaces of holomorphic supercurves
which, being motivated by supergeometry, are perturbed such as to allow for
transversality. We give an explicit construction of limiting objects for
sequences of holomorphic supercurves and prove that, in important cases, every
such sequence has a convergent subsequence provided that a suitable extension
of the classical energy is uniformly bounded. This is a version of Gromov
compactness. Finally, we introduce a topology on the moduli spaces enlarged by
the limiting objects which makes these spaces compact and metrisable.Comment: 38 page
Sensitivity of double resonance alignment magnetometers
We present an experimental study of the intrinsic magnetometric sensitivity
of an optical/rf-frequency double resonance magnetometer in which linearly
polarized laser light is used in the optical pumping and detection processes.
We show that a semi-empirical model of the magnetometer can be used to describe
the magnetic resonance spectra. Then, we present an efficient method to predict
the optimum operating point of the magnetometer, i.e., the light power and rf
Rabi frequency providing maximum magnetometric sensitivity. Finally, we apply
the method to investigate the evolution of the optimum operating point with
temperature. The method is very efficient to determine relaxation rates and
thus allowed us to determine the three collisional disalignment cross sections
for the components of the alignment tensor. Both first and second harmonic
signals from the magnetometer are considered and compared
Anticipating the content and circumstances of skill transfer: Unrealistic expectations of driver training and graduated licensing?
X-ray-provoked non-Mendelian transgenerational oncodeterminants
Cancer is the most important risk of radiation exposure. There is a definite lack of suitable test systems, human epidemiological data are only available for certain radiation types, especially not for charged particles. We use the Xiphophorus model which is genetically well characterized. As a prelude to experiments with heavy ions we report here on results obtained with x-rays to establish the necessary baseline for future studies. Apart from this direct aim we hope to obtain also a better insight in the genetical determination of cancer formation
A large sample study of spin relaxation and magnetometric sensitivity of paraffin-coated Cs vapor cells
We have manufactured more than 250 nominally identical paraffin-coated Cs
vapor cells (30 mm diameter bulbs) for multi-channel atomic magnetometer
applications. We describe our dedicated cell characterization apparatus. For
each cell we have determined the intrinsic longitudinal, \sGamma{01}, and
transverse, \sGamma{02}, relaxation rates. Our best cell shows
\sGamma{01}/2\pi\approx 0.5 Hz, and \sGamma{02}/2\pi\approx 2 Hz. We find a
strong correlation of both relaxation rates which we explain in terms of
reservoir and spin exchange relaxation. For each cell we have determined the
optimal combination of rf and laser powers which yield the highest sensitivity
to magnetic field changes. Out of all produced cells, 90% are found to have
magnetometric sensitivities in the range of 9 to 30 fTHz. Noise analysis shows
that the magnetometers operated with such cells have a sensitivity close to the
fundamental photon shot noise limit
Testing isotropy of the universe using the Ramsey resonance technique on ultracold neutron spins
Physics at the Planck scale could be revealed by looking for tiny violations
of fundamental symmetries in low energy experiments. In 2008, a sensitive test
of the isotropy of the Universe using has been performed with stored ultracold
neutrons (UCN), this is the first clock-comparison experiment performed with
free neutrons. During several days we monitored the Larmor frequency of neutron
spins in a weak magnetic field using the Ramsey resonance technique. An
non-zero cosmic axial field, violating rotational symmetry, would induce a
daily variation of the precession frequency. Our null result constitutes one of
the most stringent tests of Lorentz invariance to date.Comment: proceedings of the PNCMI2010 conferenc
The specificity and patterns of staining in human cells and tissues of p16INK4a antibodies demonstrate variant antigen binding
The validity of the identification and classification of human cancer using antibodies to detect biomarker proteins depends upon antibody specificity. Antibodies that bind to the tumour-suppressor protein p16INK4a are widely used for cancer diagnosis and research. In this study we examined the specificity of four commercially available anti-p16INK4a antibodies in four immunological applications. The antibodies H-156 and JC8 detected the same 16 kDa protein in western blot and immunoprecipitation tests, whereas the antibody F-12 did not detect any protein in western blot analysis or capture a protein that could be recognised by the H-156 antibody. In immunocytochemistry tests, the antibodies JC8 and H-156 detected a predominately cytoplasmic localised antigen, whose signal was depleted in p16INK4a siRNA experiments. F-12, in contrast, detected a predominately nuclear located antigen and there was no noticeable reduction in this signal after siRNA knockdown. Furthermore in immunohistochemistry tests, F-12 generated a different pattern of staining compared to the JC8 and E6H4 antibodies. These results demonstrate that three out of four commercially available p16INK4a antibodies are specific to, and indicate a mainly cytoplasmic localisation for, the p16INK4a protein. The F-12 antibody, which has been widely used in previous studies, gave different results to the other antibodies and did not demonstrate specificity to human p16INK4a. This work emphasizes the importance of the validation of commercial antibodies, aside to the previously reported use, for the full verification of immunoreaction specificity
Transgenic Restoration of Long-Chain n-3 Fatty Acids in Insulin Target Tissues Improves Resolution Capacity and Alleviates Obesity-Linked Inflammation and Insulin Resistance in High-Fat–Fed Mice
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