DYNAMICS OF RUSSIAN SPEAKERS` VALUE PRIORITIES (FOR EXAMPLE, THE CONCEPT OF MONEY)

В статье показана динамика ценностных приоритетов наивного носителя русского языка. Автором сделан вывод о том, что в когнитивном ощущении россиян деньги стали обладать большей значимостью и ценностью.The article shows the dynamics of value priorities of the Russian language`s naive native speaker. The author concludes money has become more important and valuable in Russian cognitive perception

Designing technology of English language teaching content based on international component

© 2015, Canadian Center of Science and Education. All rights reserved. This paper aims to develop designing technology of English language teaching content for students at higher education institution in the context of education internationalization. It highlighted the analytical, pre-designing, designing and correction-implementation stages as well as their successive phases to achieve a specific goal, i.e. English language teaching content designing in terms of international component. The materials of this paper are of practical value for teachers of foreign languages in the selecting and structuring the language teaching content in the context of education internationalization

Lessons from the Whole Exome Sequencing Effort in Populations of Russia and Tajikistan

© 2016, Springer Science+Business Media New York.In contrast with the traditional methods applied to assessment of population diversity, high-throughput sequencing technologies have a wider application in clinical practice with greater potential to find novel disease-causing variants for multifactorial disorders. Widely used test panels may not meet their goal to diagnose the patient’s condition with a full reliability since this method often does not take into account the population frequencies of analyzed genetic markers. Here, we analyzed 57 male individuals of five ethnic groups from Russia and Tajikistan using the whole exome sequencing technique (Ion AmpliSeq Exome), which resulted in detecting more than 299,000 single nucleotide polymorphisms. Samples formed clusters on the PCA plot according to the geographical location of the corresponding populations. Thereby, the methodology of whole-exome sequencing, in general, and the Ion AmpliSeq Exome panel, in particular, could be positively applied for the purposes of population genetics and for detection of the novel clinically relevant variants

Shotgun metagenomic data on the human stool samples to characterize shifts of the gut microbial profile after the Helicobacter pylori eradication therapy

© 2017 The Authors The shotgun sequencing data presented in this report are related to the research article named “Gut microbiome shotgun sequencing in assessment of microbial community changes associated with H. pylori eradication therapy” (Khusnutdinova et al., 2016) [1]. Typically, the H. pylori eradication protocol includes a prolonged two-week use of the broad-spectrum antibiotics. The presented data on the whole-genome sequencing of the total DNA from stool samples of patients before the start of the eradication, immediately after eradication and several weeks after the end of treatment could help to profile the gut microbiota both taxonomically and functionally. The presented data together with those described in Glushchenko et al. (2017) [2] allow researchers to characterize the metagenomic profiles in which the use of antibiotics could result in dramatic changes in the intestinal microbiota composition. We perform 15 gut metagenomes from 5 patients with H. pylori infection, obtained through the shotgun sequencing on the SOLiD 5500 W platform. Raw reads are deposited in the ENA under project ID PRJEB21338

Implementasi Algoritma Advanced Encryption Standard (AES) 128 Untuk Enkripsi dan Dekripsi File Dokumen

Keamanan data atau informasi adalah hal yang sangat penting bagi pengguna jaringan internet saat ini. Kasus penyadapan akan pesan atau informasi merupakan salah satu hal yang sangat merugikan, dengan adanya kemungkinan terjadinya kejadian ini, maka perlunya peningkatan dalam hal keamanan pertukaran informasi menjadi penting. Pada saat ini, keamanan pertukaran informasi ini perlu mendapatkan perhatian khusus, maka penelitian ini akan membuat suatu implementasi kriptografi algoritma AES-128 untuk enkripsi dan dekripsi data yang berupa file dokumen (PDF, DOC, TXT). Algoritma Advanced Encryption Standard (AES) dipilih karena memiliki suatu tingkat keamanan pertukaran informasi yang cukup bagus, dan pada penelitian ini diuji coba file dokumen untuk melihat kecepatan waktu yang dibutuhkan selama proses enkripsi dan dekripsi

Food behavior as a factor of health

One of the theoretical foundations for improving student health is the correct nutritional behavior of a person and the right attitude to physical education. The physiological parameters of eating behavior are determined by the body's need for consumption and digestion of food, the state of homeostasis, which maintains the stability of its functional systems, including the digestive system. The psychological parameters of eating behavior are determined by the personal attitude to eating and its methods. Analysis of risk factors for the development of metabolic syndrome in students helps to include such innovative methods in the learning process at the university as ecologization of students' knowledge, increasing the actualization of physical education among students.Одной из теоретических основ улучшения здоровья студентов является правильное пищевое поведение человека и правильное отношение к физическому воспитанию. Физиологические параметры пищевого поведения определяются потребностью организма в потреблении и переваривании пищи и определяют нутритивный статус человека. Психологические параметры пищевого поведения определяются личным отношением к еде и её потреблению. Анализ факторов риска развития метаболического синдрома у студентов помогает включать такие инновационные методы в процесс обучения в ВУЗе, как экологизация знаний студентов, повышение актуализации физической культуры среди студентов

Reservoir Topology in Deep Echo State Networks

Deep Echo State Networks (DeepESNs) recently extended the applicability of Reservoir Computing (RC) methods towards the field of deep learning. In this paper we study the impact of constrained reservoir topologies in the architectural design of deep reservoirs, through numerical experiments on several RC benchmarks. The major outcome of our investigation is to show the remarkable effect, in terms of predictive performance gain, achieved by the synergy between a deep reservoir construction and a structured organization of the recurrent units in each layer. Our results also indicate that a particularly advantageous architectural setting is obtained in correspondence of DeepESNs where reservoir units are structured according to a permutation recurrent matrix.Comment: Preprint of the paper published in the proceedings of ICANN 201

Assessing natural herd immunity to tick-borne encephalitis in Republic Sakha (Yakutia)

Tick-borne encephalitis (TBE) is a natural focal viral neuroinfection vastly spread in the mid-latitude climate zone of theEurasia. Lethal cases and disability related to TBE determine its high epidemiological significance as well as underlie undiminished attention to prevent it in endemic territories. At the same time, TBE epidemiologic features significantly differ in various geographic areas. Importantly, Republic Sakha (Yakutia) is not among TBE endemic areas in theRussian Federation. However, in the last decade an increased incidence of ixodic tick bites was registered in the Republic Sakha. A pattern of pathogen-specific population immunity is one of the most valuable criteria for assessing magnitude of epidemic process in TBE foci. Hence, our study was aimed at assessing natural herd immunity TBEV in Republic Sakha associated with elevated incidence of tick bite visits. Here, we analyzed the data regarding the rate of tick attacks in the period of 2001–2007 in Republic Sakha. Residents and individuals unvaccinated against TBEV in the city ofYakutskas well as various administrative regions were examined to record the peak incidence of tick attacks. It was found that a range of the administrative regions recording with registered of ixodic tick attacks and elevated incidence of tick bites was expanded. Moreover, the top incidence of tick bites was annually recorded in the south regions of the republic Aldanian, Neryungri, Olyekminsk, Leninsk, Khangalassky districts, city ofYakutskand its suburbs. Furthermore, TBEV-specific immunoglobulins were detected in 5.7±0.68% of the residents examined suggesting about contacts with the pathogen. In addition, the peak count of seropositive people (8.9±1.85%) was identified in Namsky district located in the central part of the republic. Overall, detection rate of TBEV-specific antibodies among general adult population (6.9±0.95%) was significantly higher compared to those observed in children (3.9±0.89%, р < 0.05). no significant differences in urban (5.8±1.12%) vs. rural population (5.63±0.84%) was found

Characterization of Dysbiotic Changes of Skin Microbiota in Contact Sports Athletes

© 2017, Springer Science+Business Media New York.Contact sports athletes often suffer from various skin disorders (inflammatory diseases of bacterial and fungal origin, atopic dermatitis, psoriasis, etc.) resulting in long breaks in training which ruin athletic performance. Wrestling implies intense skin-to-skin contact that creates perfect conditions for transmission of the infectious agents. Following the standard rules of hygiene (showering and handwashing directly after each competition and training) does not exclude the possibility to get an infection from sparring partner. To characterize the skin microbial composition of wrestlers who do not have current manifestation of any skin disorders, the metagenomic analysis was performed. Absolute predominance of Bacillus genus in metagenomic profiles of wrestlers’ skin was observed in contrast with the existing literature data. Classic microbiological approaches allowed to detect hemolytic forms of microorganisms. Wrestlers’ skin appeared to be colonized with hemolytic bacilli, whereas the non-wrestler athletes did not have such bacteria on their skin. Such dysbiotic shifts in the microbial community may cause the emergence of skin diseases. Revealed properties could help to design highly effective antiseptics for the contact sports hygiene

Gut Microbiome Shotgun Sequencing in Assessment of Microbial Community Changes Associated with H. pylori Eradication Therapy

© 2016, Springer Science+Business Media New York.Disturbance of intestinal microbiota content and functions often results in different pathological conditions. Pharmacotherapy including antibiotics use is one of the factors leading to dysbiosis. To evaluate the influence of antibiotics use on intestinal microbiota metagenomic profiles of stool, samples of 74 patients before and after Helicobacter pylori—eradication therapy—were analyzed. Evaluation of taxonomic diversity changes based on Shannon index and Bray-Curtis metrics allows to range patients according to mild, moderate, and severe risk of disturbance of intestinal microbiota pathological conditions