El racismo de género en los Estados Unidos y el Perú a propósito de Aves sin nido de Clorinda Matto de Turner

This article explores how racism, gender discrimination, and hypersexualization affected indigenous women in viceregal Peru, using Clorinda Matto de Turner’s novel Aves sin nido as a basis. Similarly, it is analyzed how these same factors also affected AfricanAmerican women in the United States during the time of slavery. In both cases, it is argued that the idea of racial behavior reinforces the repression of women who represent the minority in their respective countries.El presente artículo explora cómo el racismo, la discriminación de género y la hipersexualización afectaron a las mujeres indígenas del Perú virreinal, para lo cual se toma como base la novela Aves sin nido de Clorinda Matto de Turner. Del mismo modo, se analiza cómo estos mismos factores afectaron también a las mujeres afroamericanas estadounidenses en los tiempos de la esclavitud. Para ambos casos, se sostiene que la idea del comportamiento racial refuerza la represión contra las mujeres que representan la minoría en sus respectivos países

Controversies Revisited : A Systematic Review of the Comorbidity of Depression and Anxiety with Inflammatory Bowel Diseases.

BACKGROUND: Although mental health concerns are known to occur commonly for those with inflammatory bowel diseases (IBD), the nature of this comorbid relationship has not been systematically reviewed to date. A review in 2007 identified 5 controversies regarding anxiety/depression rates and various comparators between and within IBD. We aimed to systematically analyze and critique the current evidence regarding this comorbidity, providing an update to the 5 controversies. METHODS: Ebscohost Medline, CINAHL, Embase, and PsychINFO were searched between 2005 and 2014 using systematic review methodology. Controlled quantitative studies examining either symptoms or diagnoses of anxiety and depression in IBD were included in the review, with study quality assessed using a scale developed a priori to evaluate observational research. RESULTS: (1) IBD versus healthy controls (pooled mean proportions) (n = 13 studies): anxiety 19.1% versus 9.6%, depression 21.2% versus 13.4%; (2) IBD inactive versus IBD active disease (n = 26): anxiety 28.2% versus 66.4%, depression 19.9% versus 34.7%; (3) ulcerative colitis versus Crohn's disease (n = 28): anxiety 31% versus 37%, depression 22% versus 24.4%; (4) IBD versus other chronic medical conditions (n = 17): anxiety 41.9% versus 48.2%, depression 14.5% versus 28.4%; (5) onset of anxiety/depression before or after IBD onset (n = 2): adults more likely to develop anxiety/depression before IBD onset, but a substantial proportion develops depression after onset; an increased risk for children of developing anxiety/depression after IBD onset. CONCLUSIONS: The high rates of anxiety and depression for those with IBD, particularly when disease is active, warrant a systemic approach to screening and treatmen

Densify: An R package to reduce empty cells in dataframes of typological linguistic data

The R package densify provides a procedure to prune input data frames containing empty cells (or cells with values {?} or {NA}) to denser sub-matrices with fewer empty cells. The pruning process trades off a series of variably weighted concerns, including data retention, coding density (proportion of non-empty cells) and taxonomic diversity of rows (representing for example phylogenetic relations). Users can adapt the relative weights given to these concerns through various parameters so that the densification process best fits their needs. As such, the software is useful for several purposes, including the densification of sparse input matrices and the subsampling of large input matrices according to a procedure that is sensitive to taxonomic structure

Natural products that reduce rotavirus infectivity identified by a cell-based moderate-throughput screening assay

BACKGROUND: There is widespread interest in the use of innate immune modulators as a defense strategy against infectious pathogens. Using rotavirus as a model system, we developed a cell-based, moderate-throughput screening (MTS) assay to identify compounds that reduce rotavirus infectivity in vitro, toward a long-term goal of discovering immunomodulatory agents that enhance innate responses to viral infection. RESULTS: A natural product library consisting of 280 compounds was screened in the assay and 15 compounds that significantly reduced infectivity without cytotoxicity were identified. Time course analysis of four compounds with previously characterized effects on inflammatory gene expression inhibited replication with pre-treatment times as minimal as 2 hours. Two of these four compounds, α-mangostin and 18-β-glycyrrhetinic acid, activated NFκB and induced IL-8 secretion. The assay is adaptable to other virus systems, and amenable to full automation and adaptation to a high-throughput format. CONCLUSION: Identification of several compounds with known effects on inflammatory and antiviral gene expression that confer resistance to rotavirus infection in vitro suggests the assay is an appropriate platform for discovery of compounds with potential to amplify innate antiviral responses

Cultural macroevolution of musical instruments in South America

Musical instruments provide material evidence to study the diversity and technical innovation of music in space and time. We employed a cultural evolutionary perspective to analyse organological data and their relation to language groups and population history in South America, a unique and complex geographic area for human evolution. The ethnological and archaeological native musical instrument record, documented in three newly assembled continental databases, reveals exceptionally high diversity of wind instruments. We explored similarities in the collection of instruments for each population, considering geographic patterns and focusing on groupings associated with language families. A network analysis of panpipe organological features illustrates four regional/cultural clusters: two in the Tropical Forest and two in the Andes. Twenty-five percent of the instruments in the standard organological classification are present in the archaeological, but not in the ethnographic record, suggesting extinction events. Most recent extinctions can be traced back to European contact, causing a reduction in indigenous cultural diversity

A comparative study of parasites in three latrines from Medieval and Renaissance Brussels, Belgium (14th-17th centuries).

The aim of this study is to determine the species of parasite that infected the population of Brussels during the Medieval and Renaissance periods, and determine if there was notable variation between different households within the city. We compared multiple sediment layers from cesspits beneath three different latrines dating from the 14th–17th centuries. Helminths and protozoa were detected using microscopy and enzyme-linked immunosorbent assay (ELISA). We identified Ascaris sp., Capillaria sp., Dicrocoelium dendriticum, Entamoeba histolytica, Fasciola hepatica, Giardia duodenalis, Taenia sp. and Trichuris sp. in Medieval samples, and continuing presence of Ascaris sp., D. dendriticum, F. hepatica, G. duodenalis and Trichuris sp. into the Renaissance. While some variation existed between households, there was a broadly consistent pattern with the domination of species spread by fecal contamination of food and drink (whipworm, roundworm and protozoa that cause dysentery). These data allow us to explore diet and hygiene, together with routes for the spread of fecal–oral parasites. Key factors explaining our findings are manuring practices with human excrement in market gardens, and flooding of the polluted River Senne during the 14th–17th centuries

The Role of Soil Type in Triggering Shallow Landslides in the Alps (Lombardy, Northern Italy)

Shallow landslides due to the soil saturation induced by intense rainfall events are very common in northern Italy, particularly in the Alps and Prealps. They are usually triggered during heavy rainstorms, causing severe damage to property, and sometimes causing casualties. A historical study and analysis of shallow landslides and mud-debris flows triggered by rainfall events in Lombardy was carried out for the period of 1911–2010, over an area of 14,019 km2. In this study, intensity–duration rainfall thresholds have been defined using the frequentist approach, considering some pedological characteristics available in regional soil-related databases, such as the soil region, the textural class, and the dominant soil typological units (STU). The soil-based empirical rainfall thresholds obtained considering the soil regions of the study area were significantly different, with a lower threshold for landslide occurrence in the soil region M1 (Alps), where soils developed over siliceous parent material, with respect to the whole study area and the soil region M2 (Prealps), where soils developed over calcareous bedrocks. Furthermore, by considering textural classes, the curves were differentiated, with coarse-textured soils found more likely to triggerlandslides than fine soils. Finally, considering both texture and main soil groups, given the same rainfall duration, the rainfall amount and intensity needed to initiate a landslide increased in the following order: “coarse-skeletal” Cambisols < Umbrisols < Podzols < “fine” Cambisols. The results of this study highlighted the relevant role of pedological conditioning factors in differentiating the activation of rainfall-induced shallow landslides in a definite region. The information on soils can be used to define more precise rainfall–pedological thresholds than empirical thresholds based solely on meteorological conditions, even when they are locally defined. This knowledge is crucial for forecasting and preventing geo-hydrological processes and in developing better warning strategies to mitigate risks and to reduce socio-economic damage

Educational inequalities in mortality over four decades in Norway: prospective study of middle aged men and women followed for cause specific mortality, 1960-2000

Objectives To determine the extent to which educational inequalities in relation to mortality widened in Norway during 1960-2000 and which causes of death were the main drivers of this disparity

Advocating for a Collaborative Research Approach on Transgenerational Transmission of Trauma.

Since Myers (1915) coined the term 'shell shock' to define the prolonged suffering of soldiers returning from the Great War, the psychological and physical result of distressing experiences, known as trauma, has been of academic interest. Transgenerational transmission of trauma effects has been recorded, demonstrating that on some level, the exposure to trauma of one generation can impact individuals of a subsequent generation (Yehuda & Lehrner, 2018). Observational studies on children of holocaust survivors formed the basis of this trajectory of research (Rakoff, 1966), and eventually this phenomenon became referred to as the transgenerational transmission of trauma (TTT). Since then, TTT has been observed in several contexts, including within families who have experienced high rates historical trauma (O'Neill et al., 2016), within regions high-frequencies of historical war and terrorism (Yehuda & Lehrner, 2018) and those who have undergone famine (Ahmed, 2010). This report aims to outline several pathways (biological, psychological, and sociological) by which trauma may be transmitted across generations. Moreover, it discusses several methods of trauma assessment and the related challenges and benefits. Lastly, this report advocates a biopsychosocial approach - an interdisciplinary model using the interplay of biological, psychological, and social-environmental factors - to research TTT. By promoting the benefits of such an interdisciplinary approach we attempt to break up silos between disciplines and encourage collaboration between academics from various backgrounds researching this topic to better serve individuals impacted by TTT