963 research outputs found
Think Like a Teacher: How Reflective Educators Use Multiple Data Sources to Inform Their Practice
Teacher data use has become an increasingly central feature of American education. Messages from the public policy, research, philanthropy, and professional development arenas assert that collecting, analyzing, and interpreting data€”particularly number-based achievement data€”will increase student achievement. in this dissertation, a review of literature exploring the link between data use and achievement yielded mixed results. While increased achievement was slightly more likely when data use involved multiple types of data and/or data use strategies, its effectiveness was not consistently supported, and least apparent when tied to marginalized students. to better understand what effective data use might look like at the micro level in marginalized communities, this dissertation also includes a collective case study of three urban charter school teachers with action research experience. These reflective educators routinely used multiple types of data (e.g., achievement data; student, parent, and peer input; observation of students and peers; instructional feedback; and collaboration data), as well as professional judgment (which is rooted in teachers\u27 education, knowledge, and experience), simultaneously to solve three primary problems of practice: building relationships with students, monitoring student progress, and informing and improving instruction. This work was shaped by assessment, context, and teacher factors. Implications for research and practice are discussed, as well as the study\u27s limitations
KILKA UWAG O PRZEKŁADZIE TYTUŁÓW NA PODSTAWIE TUŁMACZEŃ NIEMIECKO-POLSKICH I POLSKO-NIEMIECKICH
The article discusses problems related to translating titles of films, literary works and academic publications from German to Polish and vice-versa. The authors emphasize aspects common to translation of all titles, and analyse typical problems occurring while rendering film and literary titles. In case of titles of academic publications formal and content-related changes are considerably smaller than, for instance, in film titles. This is due to the fact that while working on the latter translators take into account not only linguistic norms and conventions, but also references to the cultural background. A title has to be equally catchy in both source and target languages, and that is why translators perform certain operations when they are convinced that literal translation might yield poor results. Producing a title not related to the original is a borderline occurrence. The translator frequently needs to seek the golden mean between the content and form of the original and the requirements of the target language (linguistic norms, conventions, traditions).Artykuł poświęcony jest problematyce przekładu tytułów filmów, dzieł literackich oraz prac naukowych itd. z języka niemieckiego na polski i odwrotnie. Autorzy wskazują na aspekty wspólne dla wszystkich rodzajów dzieł oraz na aspekty tłumaczenia tytułów filmów i dzieł literackich, w którym bardzo ważną rolę odgrywają nie tylko konwencje, lecz także aspekty kulturowe
The characterization of tumor necrosis factor alpha (TNF-α), its role in cancerogenesis and cardiovascular system diseases and possibilities of using this cytokine as a molecular marker
The inflammatory process is directly associated with secretion of cytokines, e.g. tumor necrosis factor alpha (TNF-α). This molecule is one of the 22 proteins which belong to TNF family and is secreted mainly by: macrophages, monocytes, T lymphocyte and mast cells. The biological effects of TNF-α is possible through binding this cytokine to specific receptors - TNFR1 and TNFR2. The large number of reports provides that this cytokine plays extremely important role in cancers and cardiovascular disease - two groups of inflammatory diseases. Unfortunately, these diseases are the main cause of death in spite of advances in medicine and increasing public awareness of prevention. It is believed that better understanding both molecular potential of this cytokine and the impact in cancerogenesis and others inflammatory diseases may cause using TNF-α as a molecular marker in these diseases and will make it possible to observe the effects of anti-inflammatory therapy. It will be able to cause a drop in the incidence of these diseases and better monitoring of them
Kilka uwag o przekładzie tytułów na podstawie tłumaczeń niemiecko-polskich i polsko-niemieckich
The article discusses problems related to translating titles of films, literary works and academic publications from German to Polish and vice-versa. The authors emphasize aspects common to translation of all titles, and analyse typical problems occurring while rendering film and literary titles. In case of titles of academic publications formal and content-related changes are considerably smaller than, for instance, in film titles. This is due to the fact that while working on the latter translators take into account not only linguistic norms and conventions, but also references to the cultural background. A title has to be equally catchy in both source and target languages, and that is why translators perform certain operations when they are convinced that literal translation might yield poor results. Producing a title not related to the original is a borderline occurrence. The translator frequently needs to seek the golden mean between the content and form of the original and the requirements of the target language (linguistic norms, conventions, traditions).Artykuł poświęcony jest problematyce przekładu tytułów filmów, dzieł literackich oraz prac naukowych itd. z języka niemieckiego na polski i odwrotnie. Autorzy wskazują na aspekty wspólne dla wszystkich rodzajów dzieł oraz na aspekty tłumaczenia tytułów filmów i dzieł literackich, w którym bardzo ważną rolę odgrywają nie tylko konwencje, lecz także aspekty kulturowe
Driver – ECO-car system: design and computer simulation of dynamics
The 21st century certainly poses new challenges for the construction of means and systems of transport, particularly in the greater metropolitan areas. Issues related with public transport are generally well-known. Research studies are constructively oriented towards finding solutions to reduce energy consumption, minimize construction and maintenance costs, guarantee profitability, reduce emissions of air pollutants, and first and foremost, solutions which would be human-friendly and specifically tailored to meet the needs of the people. This paper presents the concept of a new electric ECO-car designed within the remit of the scientific and research programme at Warsaw University of Technology. The car is equipped to carry both able-bodied passengers and the disabled. The car uses an integrated drive and brake-by-wire system, as well as powered by lithium-ion batteries and a super capacitor system. During the design process special attention was also paid to ergonomic issues. Due to the theme of the conference, special attention will be paid to the dynamic properties of a complex system of driver-vehicle-road. It will show dynamic phenomena in the implementation of the so-called moose test
A Reply to Richard Wolin on Suicide Bombings
A reply to Professor Richard Wolin on his views on suicide bombings is presented. Professor Wolin refused to acknowledge any cause of misery in the poor world. He elevated Osama Bin Ladin to the rank of a god. The article considers these views as literally, wholly, and absolutely false. The article proposes that avoidance, falsehood, implication, and omission are not a proper response to moral inquiry
novel analytical approaches to characterize particles in biopharmaceuticals
Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers). These impurities can affect product stability, as well as cause adverse effects once introduced into the human body. Particulate impurities are present over a wide range of sizes (from nanometers to millimeters) making them difficult to characterize by using a single method.Novel drug products may also contain particles that act as the active pharmaceutical ingredient (e.g., living cells) or a drug delivery vehicle (e.g., lipid nanoparticles). Unwanted immunotoxicity and inconsistent in vivo functionality can result from particle instability and aggregate formation. Therefore, the efficacy and safety of these therapeutics is dependent on the particle composition, quantity and size distribution.Consequently, well-established methods are required to quantify and characterize particles in the submicron- and micron-size ranges. In this thesis, we developed new approaches which allow for comprehensive characterization of the particle populations present in biopharmaceutical products, both as impurities or as API. Furthermore, the performed work focused on comparing different particle characterization techniques to allow a better understanding of the limitations and strengths of each method applied. Drug Delivery Technolog
Nuclear Pedigree Criteria for the Identification of Individuals Suspected to be at Risk of an Inherited Predisposition to Renal Cancer
Renal clear cell carcinomas represent about 3% of all visceral cancers and account for approximately 85% of renal cancers in adults. Environmental and genetic factors are involved in the development of renal cancer. Although to date there are 19 hereditary syndromes described in which renal cell cancer may occur, only four syndromes with an unequivocal genetic predisposition to renal cell carcinoma have been identified: VHL syndrome (mutations in the VHL gene), hereditary clear cell carcinoma (translocations t(3:8), t(2:3)), hereditary papillary carcinoma (mutations in the MET protooncogene) and tuberous sclerosis (mutations in the TSC1 and TSC2 genes). Little is known genetically about the other forms of familial renal cell cancer. Since there is a growing awareness about the necessity of early intervention, clinical criteria have been developed that aid in the identification of hereditary forms of renal cancer. The aim of the current study was to identify minimal inclusion criteria so that nuclear pedigree families can be ascertained for risk assessment and/or kidney tumour screening. The results reveal that inclusion features described herein, such as (a) renal clear cell cancer diagnosed before 55 years of age, and (b) renal clear cell cancer and gastric cancer or lung cancer among first degree relatives, are useful in identifying suspected hereditary clear cell renal cancer patients
Structural Instability of Tropomyosin FHC Mutants D175N and E180G Probed by Limited Trypsin Cleavage
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