356 research outputs found
Parental involvement in elite junior slalom canoeing
2016 Copyright © Association for Applied Sport Psychology This study's aim was to examine elite youth athletes’ views on parental involvement in training, competition, and at home. Eight canoeists were interviewed up to 4 times and completed written diaries over a 6-week period. Results indicated that parents were generally deemed to have a positive influence through domain specific and cross-domain behaviors. Positive behaviors included parents focusing on their children's holistic development at home, motivational and constructive evaluation at training, and limiting demands on athletes through the provision of practical support, reading and understanding the situation and their child, and supporting the development of growth mind-set across all domains
Multiscale analysis of the randomization limits of the chromosomal gene organization between Lepidoptera and Diptera
How chromosome gene organization and gene content evolve among distantly related and structurally malleable genomes remains unresolved. This is particularly the case when considering different insect orders. We have compared the highly contiguous genome assemblies of the lepidopteran Danaus plexippus and the dipteran Drosophila melanogaster, which shared a common ancestor around 290 Ma. The gene content of 23 out of 30 D. plexippus chromosomes was significantly associated with one or two of the six chromosomal elements of the Drosophila genome, denoting common ancestry. Despite the phylogenetic distance, 9.6% of the 1-to-1 orthologues still reside within the same ancestral genome neighbourhood. Furthermore, the comparison D. plexippus–Bombyx mori indicated that the rates of chromosome repatterning are lower in Lepidoptera than in Diptera, although still within the same order of magnitude. Concordantly, 14 developmental gene clusters showed a higher tendency to retain full or partial clustering in D. plexippus, further supporting that the physical association between the SuperHox and NK clusters existed in the ancestral bilaterian. Our results illuminate the scope and limits of the evolution of the gene organization and content of the ancestral chromosomes to the Lepidoptera and Diptera while helping reconstruct portions of the genome in their most recent common ancestor
Randomised controlled trial of health assessments for older Australian veterans and war widows
The document attached has been archived with permission from the editor of the Medical Journal of Australia (09 January 2008). An external link to the publisher’s copy is included.Objective: To assess the effect of home-based health assessments for older Australians on health-related quality of life, hospital and nursing home admissions, and death. Design: Randomised controlled trial of the effect of health assessments over 3 years. Participants and setting: 1569 community-living veterans and war widows receiving full benefits from the Department of Veterans’ Affairs and aged 70 years or over were randomly selected in 1997 from 10 regions of New South Wales and Queensland and randomly allocated to receive either usual care (n = 627) or health assessments (n = 942). Intervention: Annual or 6-monthly home-based health assessments by health professionals, with telephone follow-up, and written report to a nominated general practitioner. Main outcome measures: Differences in health-related quality of life, admission to hospital and nursing home, and death over 3 years of follow-up. Results: 3-year follow-up interviews were conducted for 1031 participants. Intervention-group participants who remained in the study reported higher quality of life than control-group participants (difference in Physical Component Summary score, 0.90; 95% CI, 0.05–1.76; difference in Mental Component Summary score, 1.36; 95% CI, 0.40–2.32). There was no significant difference in the probability of hospital admission or death between intervention and control groups over the study period. Significantly more participants in the intervention group were admitted to nursing homes compared with the control group (30 v 7; P < 0.01). Conclusions: Health assessments for older people may have small positive effects on quality of life for those who remain resident in the community, but do not prevent deaths. Assessments may increase the probability of nursing-home placement.Julie E Byles, Meredith Tavener, Rachel L O’Connell, Balakrishnan R Nair, Nick H Higginbotham, Claire L Jackson, Mary E McKernon, Lyn Francis, Richard F Heller, Jonathan W Newbury, John E Marley and Brendan G Goodge
Oil Body Formation in Marchantia polymorpha Is Controlled by MpC1HDZ and Serves as a Defense against Arthropod Herbivores
A Transient Sub-Eddington Black Hole X-ray Binary Candidate in the Dust Lanes of Centaurus A
We report the discovery of a bright X-ray transient, CXOU J132527.6-430023,
in the nearby early-type galaxy NGC 5128. The source was first detected over
the course of five Chandra observations in 2007, reaching an unabsorbed
outburst luminosity of 1-2*10^38 erg/s in the 0.5-7.0 keV band before returning
to quiescence. Such luminosities are possible for both stellar-mass black hole
and neutron star X-ray binary transients. Here, we attempt to characterize the
nature of the compact object. No counterpart has been detected in the optical
or radio sky, but the proximity of the source to the dust lanes allows for the
possibility of an obscured companion. The brightness of the source after a >100
fold increase in X-ray flux makes it either the first confirmed transient
non-ULX black hole system in outburst to be subject to detailed spectral
modeling outside the Local Group, or a bright (>10^38 erg/s) transient neutron
star X-ray binary, which are very rare. Such a large increase in flux would
appear to lend weight to the view that this is a black hole transient. X-ray
spectral fitting of an absorbed power law yielded unphysical photon indices,
while the parameters of the best-fit absorbed disc blackbody model are typical
of an accreting ~10 Msol black hole in the thermally dominant state.Comment: 8 pages, 6 figures, accepted for publication in Ap
Deep Chandra observations of Pictor A
This article has been accepted for publication in Monthly Notices of the Royal Astronomical Society. ©: 2015 The Authors. Published by Oxford University Press on behalf of the Royal Astronomical Society.We report on deep Chandra observations of the nearby broad-line radio galaxy Pictor A, which we combine with new Australia Telescope Compact Array (ATCA) observations. The new X-ray data have a factor 4 more exposure than observations previously presented and span a 15-year time baseline, allowing a detailed study of the spatial, temporal and spectral properties of the AGN, jet, hotspot and lobes. We present evidence for further time variation of the jet, though the flare that we reported in previous work remains the most significantly detected time-varying feature. We also confirm previous tentative evidence for a faint counterjet. Based on the radio through X-ray spectrum of the jet and its detailed spatial structure, and on the properties of the counterjet, we argue that inverse-Compton models can be conclusively rejected, and propose that the X-ray emission from the jet is synchrotron emission from particles accelerated in the boundary layer of a relativistic jet. For the first time, we find evidence that the bright western hotspot is also time-varying in X-rays, and we connect this to the small-scale structure in the hotspot seen in high-resolution radio observations. The new data allow us to confirm that the spectrum of the lobes is in good agreement with the predictions of an inverse-Compton model and we show that the data favour models in which the filaments seen in the radio images are predominantly the result of spatial variation of magnetic fields in the presence of a relatively uniform electron distribution.Peer reviewe
Plant mRNAs move into a fungal pathogen via extracellular vesicles to reduce infection
Cross-kingdom small RNA trafficking between hosts and microbes modulates gene expression in the interacting partners during infection. However, whether other RNAs are also transferred is unclear. Here, we discover that host plant Arabidopsis thaliana delivers mRNAs via extracellular vesicles (EVs) into the fungal pathogen Botrytis cinerea. A fluorescent RNA aptamer reporter Broccoli system reveals host mRNAs in EVs and recipient fungal cells. Using translating ribosome affinity purification profiling and polysome analysis, we observe that delivered host mRNAs are translated in fungal cells. Ectopic expression of two transferred host mRNAs in B. cinerea shows that their proteins are detrimental to infection. Arabidopsis knockout mutants of the genes corresponding to these transferred mRNAs are more susceptible. Thus, plants have a strategy to reduce infection by transporting mRNAs into fungal cells. mRNAs transferred from plants to pathogenic fungi are translated to compromise infection, providing knowledge that helps combat crop diseases.</p
The marketing of herd health and production management services on Dutch dairy farms: perceptions of dairy farmers and their veterinary surgeons
A questionnaire-based survey on veterinary herd health and production management services was conducted on 194 specialist dairy veterinarians and 466 dairy farmers. The farmers were randomly selected from greater than 6,000 farmer clients of the surveyed veterinarians. This paper reports these survey findings and the findings of an earlier survey conducted among the veterinarians. The survey included questions on the attributes of the service itself, the practitioners delivering the service, reasons for participation and the expected future of herd health and production management services. Reasons farmers participated in herd health and production management programmes included; access to routine screening of their herd; increasing profits; and receiving regular veterinary advice or solutions to remedy existing problems. Advantages of participation named included: good management support; higher profits; structural solutions to problems; and being better informed. Differences between farming styles were observed, pointing to the different needs and goals of farming styles. Farmers cited high costs and the time investment required as major disadvantages. The proportion of farmers citing these reasons was lower than expected by the veterinarians. In the future, preventive healthcare will be the main reason of farmers to participate. Farmers who are not using the service can potentially be encouraged to engage the services after gaining increased insight into the herd health and management service structure, the planning of activities, the cost-benefit of the service, veterinary surgeons being more co-operative with other farm advisors and veterinarians being more willing to pay attention to quality issues on the dairy farm
The miR-144/451 locus is required for erythroid homeostasis.
The process of erythropoiesis must be efficient and robust to supply the organism with red bloods cells both under condition of homeostasis and stress. The microRNA (miRNA) pathway was recently shown to regulate erythroid development. Here, we show that expression of the locus encoding miR-144 and miR-451 is strictly dependent on Argonaute 2 and is required for erythroid homeostasis. Mice deficient for the miR-144/451 cluster display a cell autonomous impairment of late erythroblast maturation, resulting in erythroid hyperplasia, splenomegaly, and a mild anemia. Analysis of gene expression profiles from wild-type and miR-144/451-deficient erythroblasts revealed that the miR-144/451 cluster acts as a "tuner" of gene expression, influencing the expression of many genes. MiR-451 imparts a greater impact on target gene expression than miR-144. Accordingly, mice deficient in miR-451 alone exhibited a phenotype indistinguishable from miR-144/451-deficient mice. Thus, the miR-144/451 cluster tunes gene expression to impart a robustness to erythropoiesis that is critical under conditions of stress
The magnetized medium around the radio galaxy B2 0755+37: an interaction with the intra-group gas
We explore the magneto-ionic environment of the isolated radio galaxy B2
0755+37 using detailed imaging of the distributions of Faraday rotation and
depolarization over the radio source from Very Large Array observations at
1385,1465 and 4860 MHz and new X-ray data from XMM-Newton. The Rotation Measure
(RM) distribution is complex, with evidence for anisotropic fluctuations in two
regions. The approaching lobe shows low and uniform RM in an unusual `stripe'
along an extension of the jet axis and a linear gradient transverse to this
axis over its Northern half. The leading edge of the receding lobe shows
arc-like RM structures with sign reversals. Elsewhere, the RM structures are
reasonably isotropic. The RM power spectra are well described by cut-off power
laws with slopes ranging from 2.1 to 3.2 in different sub-regions. The
corresponding magnetic-field autocorrelation lengths, where well-determined,
range from 0.25 to 1.4 kpc. It is likely that the fluctuations are mostly
produced by compressed gas and field around the leading edges of the lobes. We
identify areas of high depolarization around the jets and inner lobes. These
could be produced by dense gas immediately surrounding the radio emission
containing a magnetic field which is tangled on small scales. We also identify
four ways in which the well known depolarization (Faraday depth) asymmetry
between jetted and counter-jetted lobes of extended radio sources can be
modified by interactions with the surrounding medium.Comment: 16 pages, 13 figures, accepted for publication in MNRAS. Full
resolution paper available at: ftp://ftp.ira.inaf.it/pub/outgoing/guidetti/
Subjects: Cosmology and Extragalactic Astrophysics (astro-ph.CO
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