9 research outputs found
Clinical and Epidemiological Characteristics of Streptococcus suis Infections in Catalonia, Spain
Introduction: Streptococcus suis (S. suis) is a human zoonotic pathogen of occupational origin, with infection acquired through contact with live pigs or pig meat. Pig farming is one of Catalonia's biggest industries and as a result this region of Spain has one of the highest density pig populations per km2. The aim of our study was to describe the infections caused by S. suis occurring in that area over a 9-year period. Materials and Methods: A retrospective, multi-center study was carried out by searching records from 15 hospitals in Catalonia for the period between 2010 and 2019. Results: Over the study period altogether nine cases of S. suis infection were identified in five hospitals, with five of these cases occurring in the 2018-2019 period. The mean age of patients was 48 ± 8.9 years and all of them were males. Five patients (55.6%) worked in pig farms. The most frequent manifestation of infection was meningitis (5 cases; 55.6%) followed by septic arthritis (3 cases; 33.3%). None of the patients died at 30 days; nonetheless, 4 developed hearing loss as a long-term complication. Conclusion: The most commonly identified S. suis infection was meningitis. Over 50% of the episodes occurred in the last 2 years and have affected pig farm workers. Further surveillance is needed in order to know its prevalence
Clinical and Epidemiological Characteristics of Streptococcus suis Infections in Catalonia, Spain
Streptococcus suis (S. suis) is a human zoonotic pathogen of occupational origin, with infection acquired through contact with live pigs or pig meat. Pig farming is one of Catalonia's biggest industries and as a result this region of Spain has one of the highest density pig populations per km 2. The aim of our study was to describe the infections caused by S. suis occurring in that area over a 9-year period. A retrospective, multi-center study was carried out by searching records from 15 hospitals in Catalonia for the period between 2010 and 2019. Over the study period altogether nine cases of S. suis infection were identified in five hospitals, with five of these cases occurring in the 2018-2019 period. The mean age of patients was 48 ± 8.9 years and all of them were males. Five patients (55.6%) worked in pig farms. The most frequent manifestation of infection was meningitis (5 cases; 55.6%) followed by septic arthritis (3 cases; 33.3%). None of the patients died at 30 days; nonetheless, 4 developed hearing loss as a long-term complication. The most commonly identified S. suis infection was meningitis. Over 50% of the episodes occurred in the last 2 years and have affected pig farm workers. Further surveillance is needed in order to know its prevalence
Dynamic chronic rectal obstruction causing a severe colonic dilatation in a cat
Case summary A 5-year-old male neutered domestic shorthair cat was presented to our referral centre with a 13 month history of chronic tenesmus due to malunion of the right caudal iliac body. Constipation and pelvic canal stenosis were initially addressed by the referring veterinarian with a right femoral head and neck excision and a right acetabulectomy without observable clinical improvement. At admission, abdominal radiographs revealed severe colonic distension and a narrowed pelvic canal caused by the right proximal femur. Rectal examination and colonography revealed a dynamic compression of the rectum, which worsened with femoral abduction and improved with femoral adduction. A right hindlimb amputation was performed to relieve the obstruction. The cat defaecated 2 days postoperatively and was discharged uneventfully. Neither faecal tenesmus nor dyschaezia were observed over the following 10 months. Relevance and novel information The dynamic nature of the rectal obstruction most likely prevented the development of an irreversible colonic dilatation leading to a megacolon. This is the first report describing a chronic dynamic rectal compression, which was successfully managed with a right hindlimb amputation without the need for subtotal colectomy
Leaf:fruit ratio and irrigation supply affect seasonal changes in minerals, organic acids and sugars of mango fruit
Laboratori bibliotecari Fanzins Atemporals
El Servei de Biblioteques de la Universitat AutĂČnoma de Barcelona (UAB) ha celebrat els dies 7, 8 i 9 de febrer del 2024 el "Laboratori bibliotecari Fanzins Atemporals UAB", una experiĂšncia d'innovaciĂł, cocreaciĂł i participaciĂł ciutadana al campus de Bellaterra. La iniciativa forma part del projecte Laboratorios Bibliotecarios, de la SubdirecciĂł General de CoordinaciĂł BibliotecĂ ria (Ministeri de Cultura), i parteix d'una temĂ tica concreta: la Col·lecciĂł Digital de Fanzins UAB, disponible en obert al repositori institucional DipĂČsit Digital de Documents de la UAB (DDD-UAB). La Col·lecciĂł Fanzins UAB estĂ formada per un total de 849 tĂtols, recopilats al llarg de mĂ©s de 30 anys pel professor de la Facultat de CiĂšncies de la ComunicaciĂł (UAB) Eugeni Giral, des de la dĂšcada dels 70 fins a principis dels anys 2000. GrĂ cies al procĂ©s de digitalitzaciĂł finançat amb diners pĂșblics, la Biblioteca de ComunicaciĂł i Hemeroteca General (UAB) retorna expressions (culturals) que s'han construĂŻt majoritĂ riament de forma col·lectiva. Els objectius d'aquest laboratori han estat: crear les condicions adients perquĂš la comunitat universitĂ ria i altres persones interessades reinterpretin i reutilitzin la Col·leciĂł digitalizada Fanzins UAB; generar escenaris d'experimentaciĂł, codisseny i cocreaciĂł a partir d'una de les "col·leccions especials" del Servei de Biblioteques, la Col·lecciĂł Fanzins UAB; prototipar col·lectivament nous usos de la Col·lecciĂł Fanzins UAB; Crear una xarxa de persones i col·lectius interessats en les publicacions autoeditades i aspectes comuns que caracteritzen els fanzins i que permeten emergir expressions i visibilitzar actors que no apareixen en els mitjans de comunicaciĂł tradicionals. Participants, promotors i mentors del laboratori s'han organitzat en grups de treball i han prototipat dos projectes, que permeten ampliar els coneixements generats a travĂ©s d'aquestes publicacions, sovint autoeditades i que defugen els circuits clĂ ssics de distribuciĂł comercial. Les tres jornades del Laboratori Fanzins Atemporals UAB s'han celebrat al COMTEC Centre de la Biblioteca de ComunicaciĂł i Hemeroteca General (UAB). El Servei de Biblioteques UAB tĂ© previst seguir impulsant noves edicions de laboratoris bibliotecaris
Analysis of Latino populations from GALA and MEC studies reveals genomic loci with biased local ancestry estimation
Motivation: Local ancestry analysis of genotype data from recently admixed populations (e.g. Latinos, African Americans) provides key insights into population history and disease genetics. Although methods for local ancestry inference have been extensively validated in simulations (under many unrealistic assumptions), no empirical study of local ancestry accuracy in Latinos exists to date. Hence, interpreting findings that rely on local ancestry in Latinos is challenging. Results: Here, we use 489 nuclear families from the mainland USA, Puerto Rico and Mexico in conjunction with 3204 unrelated Latinos from the Multiethnic Cohort study to provide the first empirical characterization of local ancestry inference accuracy in Latinos. Our approach for identifying errors does not rely on simulations but on the observation that local ancestry in families follows Mendelian inheritance. We measure the rate of local ancestry assignments that lead to Mendelian inconsistencies in local ancestry in trios (MILANC), which provides a lower bound on errors in the local ancestry estimates. We show that MILANC rates observed in simulations underestimate the rate observed in real data, and that MILANC varies substantially across the genome. Second, across a wide range of methods, we observe that loci with large deviations in local ancestry also show enrichment in MILANC rates. Therefore, local ancestry estimates at such loci should be interpreted with caution. Finally, we reconstruct ancestral haplotype panels to be used as reference panels in local ancestry inference and show that ancestry inference is significantly improved by incoroprating these reference panels. Availability and implementation: We provide the reconstructed reference panels together with the maps of MILANC rates as a public resource for researchers analyzing local ancestry in Latinos at http://bogdanlab.pathology.ucla.edu. Contact: [email protected] Supplementary information: Supplementary data are available at Bioinformatics online