Revisiting the dust destruction efficiency of supernovae

Dust destruction by supernovae is one of the main processes removing dust from the interstellar medium (ISM). Estimates of the efficiency of this process, both theoretical and observational, typically assume a shock propagating into a homogeneous medium, whereas the ISM possesses significant substructure in reality. We self-consistently model the dust and gas properties of the shocked ISM in three supernova remnants (SNRs), using X-ray and infrared (IR) data combined with corresponding emission models. Collisional heating by gas with properties derived from X-ray observations produces dust temperatures too high to fit the far-IR fluxes from each SNR. An additional colder dust component is required, which has a minimum mass several orders of magnitude larger than that of the warm dust heated by the X-ray emitting gas. Dust-to-gas mass ratios indicate that the majority of the dust in the X-ray emitting material has been destroyed, while the fraction of surviving dust in the cold component is plausibly close to unity. As the cold component makes up virtually all the total dust mass, destruction timescales based on homogeneous models, which cannot account for multiple phases of shocked gas and dust, may be significantly overestimating actual dust destruction efficiencies, and subsequently underestimating grain lifetimes

Infrared Emission from Supernova Remnants: Formation and Destruction of Dust

We review the observations of dust emission in supernova rem- nants (SNRs) and supernovae (SNe). Theoretical calculations suggest that SNe, particularly core-collapse, should make significant quantities of dust, perhaps as much as a solar mass. Observations of extragalactic SNe have yet to find anywhere near this amount, but this may be the result of observa- tional limitations. SN 1987A, in the process of transitioning from a SN to an SNR, does show signs of a significant amount of dust forming in its ejecta, but whether this dust will survive the passage of the reverse shock to be injected into the ISM is unknown. IR observations of SNRs have not turned up significant quantities of dust, and the dust that is observed is generally swept-up by the forward shock, rather than created in the ejecta. Because the shock waves also destroy dust in the ISM, we explore the question of whether SNe might be net destroyers, rather than net creators of dust in the universe.Comment: Published in the Springer Handbook of Supernova

The dust content of the Crab Nebula

We have modelled the near-infrared to radio images of the Crab Nebula with a Bayesian SED model to simultaneously fit its synchrotron, interstellar (IS), and supernova dust emission. We infer an IS dust extinction map with an average AV = 1.08 ± 0.38 mag, consistent with a small contribution (22 per cent) to the Crab’s overall infrared emission. The Crab’s supernova dust mass is estimated to be between 0.032 and 0.049 M (for amorphous carbon grains) with an average dust temperature Tdust = 41 ± 3 K, corresponding to a dust condensation efficiency of 8–12 per cent. This revised dust mass is up to an order of magnitude lower than some previous estimates, which can be attributed to our different IS dust corrections, lower SPIRE flux densities, and higher dust temperatures than were used in previous studies. The dust within the Crab is predominantly found in dense filaments south of the pulsar, with an average V-band dust extinction of AV = 0.20–0.39 mag, consistent with recent optical dust extinction studies. The modelled synchrotron power-law spectrum is consistent with a radio spectral index αradio = 0.297 ± 0.009 and an infrared spectral index αIR = 0.429 ± 0.021. We have identified a millimetre excess emission in the Crab’s central regions, and argue that it most likely results from two distinct populations of synchrotron emitting particles. We conclude that the Crab’s efficient dust condensation (8–12 per cent) provides further evidence for a scenario where supernovae can provide substantial contributions to the IS dust budgets in galaxies

The Herschel Exploitation of Local Galaxy Andromeda (HELGA) II: Dust and Gas in Andromeda

We present an analysis of the dust and gas in Andromeda, using Herschel images sampling the entire far-infrared peak. We fit a modified-blackbody model to ~4000 quasi-independent pixels with spatial resolution of ~140pc and find that a variable dust-emissivity index (beta) is required to fit the data. We find no significant long-wavelength excess above this model suggesting there is no cold dust component. We show that the gas-to-dust ratio varies radially, increasing from ~20 in the center to ~70 in the star-forming ring at 10kpc, consistent with the metallicity gradient. In the 10kpc ring the average beta is ~1.9, in good agreement with values determined for the Milky Way (MW). However, in contrast to the MW, we find significant radial variations in beta, which increases from 1.9 at 10kpc to ~2.5 at a radius of 3.1kpc and then decreases to 1.7 in the center. The dust temperature is fairly constant in the 10kpc ring (ranging from 17-20K), but increases strongly in the bulge to ~30K. Within 3.1kpc we find the dust temperature is highly correlated with the 3.6 micron flux, suggesting the general stellar population in the bulge is the dominant source of dust heating there. At larger radii, there is a weak correlation between the star formation rate and dust temperature. We find no evidence for 'dark gas' in M31 in contrast to recent results for the MW. Finally, we obtained an estimate of the CO X-factor by minimising the dispersion in the gas-to-dust ratio, obtaining a value of (1.9+/-0.4)x10^20 cm^-2 [K kms^-1]^-1.Comment: 19 pages, 18 figures. Submitted to ApJ April 2012; Accepted July 201

A G-quadruplex-binding compound showing anti-tumour activity in an in vivo model for pancreatic cancer

We report here that a tetra-substituted naphthalene-diimide derivative (MM41) has significant in vivo anti-tumour activity against the MIA PaCa-2 pancreatic cancer xenograft model. IV administration with a twice-weekly 15 mg/kg dose produces ca 80% tumour growth decrease in a group of tumour-bearing animals. Two animals survived tumour-free after 279 days. High levels of MM41 are rapidly transported into cell nuclei and were found to accumulate in the tumour. MM41 is a quadruplex-interactive compound which binds strongly to the quadruplexes encoded in the promoter sequences of the BCL-2 and k-RAS genes, both of which are dis-regulated in many human pancreatic cancers. Levels of BCL-2 were reduced by ca 40% in tumours from MM41-treated animals relative to controls, consistent with BCL-2 being a target for MM41. Molecular modelling suggests that MM41 binds to a BCL-2 quadruplex in a manner resembling that previously observed in co-crystal structures with human telomeric quadruplexes. This supports the concept that MM41 (and by implication other quadruplex-targeting small molecules) can bind to quadruplex-forming promoter regions in a number of genes and down-regulate their transcription. We suggest that quadruplexes within those master genes that are up-regulated drivers for particular cancers, may be selective targets for compounds such as MM41

Spontaneous expectoration of pulmonary metastases in a child with osteogenic sarcoma

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/148355/1/pbc27611.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/148355/2/pbc27611_am.pd

A Herschel PACS and SPIRE study of the dust content of the Cassiopeia A supernova remnant

Using the 3.5-m Herschel Space Observatory, imaging photometry of Cas A has been obtained in six bands between 70 and 500 μm with the PACS and SPIRE instruments, with angular resolutions ranging from 6 to 37”. In the outer regions of the remnant the 70-μm PACS image resembles the 24-μm image Spitzer image, with the emission attributed to the same warm dust component, located in the reverse shock region. At longer wavelengths, the three SPIRE bands are increasingly dominated by emission from cold interstellar dust knots and filaments, particularly across the central, western and southern parts of the remnant. Nonthermal emission from the northern part of the remnant becomes prominent at 500 μm. We have estimated and subtracted the contributions from the nonthermal, warm dust and cold interstellar dust components. We confirm and resolve for the first time a cool (~35 K) dust component, emitting at 70-160 μm, that is located interior to the reverse shock region, with an estimated mass of 0.075

The enigmatic nature of the circumstellar envelope and bow shock surrounding Betelgeuse as revealed by Herschel

Context. The interaction between stellar winds and the interstellar medium (ISM) can create complex bow shocks. The photometers on board the Herschel Space Observatory are ideally suited to studying the morphologies of these bow shocks. Aims. We aim to study the circumstellar environment and wind-ISM interaction of the nearest red supergiant, Betelgeuse. Methods.Herschel PACS images at 70, 100, and 160 μm and SPIRE images at 250, 350, and 500 μm were obtained by scanning the region around Betelgeuse. These data were complemented with ultraviolet GALEX data, near-infrared WISE data, and radio 21 cm GALFA-HI data. The observational properties of the bow shock structure were deduced from the data and compared with hydrodynamical simulations. Results. The infrared Herschel images of the environment around Betelgeuse are spectacular, showing the occurrence of multiple arcs at ~6–7′ from the central target and the presence of a linear bar at ~9′. Remarkably, no large-scale instabilities are seen in the outer arcs and linear bar. The dust temperature in the outer arcs varies between 40 and 140 K, with the linear bar having the same colour temperature as the arcs. The inner envelope shows clear evidence of a non-homogeneous clumpy structure (beyond 15′′), probably related to the giant convection cells of the outer atmosphere. The non-homogeneous distribution of the material even persists until the collision with the ISM. A strong variation in brightness of the inner clumps at a radius of ~2′ suggests a drastic change in mean gas and dust density ~32 000 yr ago. Using hydrodynamical simulations, we try to explain the observed morphology of the bow shock around Betelgeuse. Conclusions. Different hypotheses, based on observational and theoretical constraints, are formulated to explain the origin of the multiple arcs and the linear bar and the fact that no large-scale instabilities are visible in the bow shock region. We infer that the two main ingredients for explaining these phenomena are a non-homogeneous mass-loss process and the influence of the Galactic magnetic field. The hydrodynamical simulations show that a warm interstellar medium, reflecting a warm neutral or partially ionized medium, or a higher temperature in the shocked wind also prevent the growth of strong instabilities. The linear bar is probably an interstellar structure illuminated by Betelgeuse itself

The origin of dust in galaxies revisited: the mechanism determining dust content

The origin of cosmic dust is a fundamental issue in planetary science. This paper revisits the origin of dust in galaxies, in particular, in the Milky Way, by using a chemical evolution model of a galaxy composed of stars, interstellar medium, metals (elements heavier than helium), and dust. We start from a review of time-evolutionary equations of the four components, and then, we present simple recipes for the stellar remnant mass and yields of metal and dust based on models of stellar nucleosynthesis and dust formation. After calibrating some model parameters with the data from the solar neighborhood, we have confirmed a shortage of the stellar dust production rate relative to the dust destruction rate by supernovae if the destruction efficiency suggested by theoretical works is correct. If the dust mass growth by material accretion in molecular clouds is active, the observed dust amount in the solar neighborhood is reproduced. We present a clear analytic explanation of the mechanism for determining dust content in galaxies after the activation of accretion growth: a balance between accretion growth and supernova destruction. Thus, the dust content is independent of the uncertainty of the stellar dust yield after the growth activation. The timing of the activation is determined by a critical metal mass fraction which depends on the growth and destruction efficiencies. The solar system formation seems to have occurred well after the activation and plenty of dust would have existed in the proto-solar nebula.Comment: 12 pages, 11 figure