16 research outputs found
Jorge A. Swieca's contributions to quantum field theory in the 60s and 70s and their relevance in present research
After revisiting some high points of particle physics and QFT of the two
decades from 1960 to 1980, I comment on the work by Jorge Andre Swieca. I
explain how it fits into the quantum field theory during these two decades and
draw attention to its relevance to the ongoing particle physics research. A
particular aim of this article is to direct thr readers mindfulness to the
relevance of what at the time of Swieca was called "the Schwinger Higgs
screening mechanism". which, together with recent ideas which generalize the
concept of gauge theories, has all the ingredients to revolutionize the issue
of gauge theories and the standard model.Comment: 49 pages, expansion and actualization of text, improvement of
formulations and addition of many references to be published in EPJH -
Historical Perspectives on Contemporary Physic
Youth mental health: a new stream of mental health care for adolescents and young adults
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ICF research at Los Alamos
It is apparent that short wavelength lasers (<500 nm) provide efficient coupling of laser energy into ICF target compression. KrF lasers (248 nm) operate at near-optimum wavelength and provide other potential benefits to ICF target coupling (e.g., bandwidth) and applications (high wallplug efficiency and relatively low cost). However, no driver technology has yet been shown to meet all of the requirements for a high-gain ICF capability at a currently acceptable cost, and there are still significant uncertainties in the driver-target coupling and capsule hydrodynamics that must be addressed. The Los Alamos research program is designed to assess the potential of KrF lasers for ICF and to determine the feasibility of achieving high gain in the laboratory with a KrF laser driver. Major efforts in KrF laser development and technology, target fabrication and materials development, and laser-matter interaction and hydrodynamics research are discussed. 27 refs., 10 figs
Survival and freedom from progression in autotransplant lymphoma patients is independent of stem cell source: Further follow-up from the original randomised study to assess engraftment
Peripheral blood progenitor cells (PBPCs) have become the stem cell source of choice in autologous transplantation. In a prospective randomised trial, we previously demonstrated that autologous transplantation using filgrastim-mobilised PBPCs resulted in faster haematopoietic recovery with shorter hospitalisation and reduced platelet transfusions compared to bone marrow transplant (BMT). This study is a follow-up analysis evaluating the long-term clinical outcome. Seventy-two patients with advanced Hodgkin's disease or high-grade lymphoma were randomised to receive either filgrastim-mobilised PBPCs (n = 37) or bone marrow (n = 35) after BEAM chemotherapy. Fourteen patients withdrew from the study before commencing high-dose chemotherapy. Fourteen of the 58 patients who received treatment with chemotherapy and transplant have died, 6 (19%) in the ABMT arm and 8 (30%) in the PBPC transplant (PBPCT) arm. Twenty-five patients (81%) in the ABMT arm and 17 (63%) in the PBPCT arm, who received treatment, were in complete remission at the date of last follow-up. Progression-free survival and overall survival (OS) were similar for both arms (OS 81% at 46 months for ABMT versus 63% for PBPC; p = 0.38). Further prospective studies with larger number of patients need to be done to assess which source of stem cells may translate into a long-term clinical benefit for the patient