2,951 research outputs found
Wind tunnel tests of a zero length, slotted-lip engine air inlet for a fixed nacelle V/STOL aircraft
Zero length, slotted lip inlet performance and associated fan blade stresses were determined during model tests using a 20 inch diameter fan simulator in the NASA-LeRC 9 by 15 foot low speed wind tunnel. The model configuration variables consisted of inlet contraction ratio, slot width, circumferential extent of slot fillers, and length of a constant area section between the inlet throat and fan face. The inlet performance was dependent on slot gap width and relatively independent of inlet throat/fan face spacer length and slot flow blockage created by 90 degree slot fillers. Optimum performance was obtained at a slot gap width of 0.36 inch. The zero length, slotted lip inlet satisfied all critical low speed inlet operating requirements for fixed horizontal nacelles subsonic V/STOL aircraft
Analysis of Three-Dimensional Protein Images
A fundamental goal of research in molecular biology is to understand protein
structure. Protein crystallography is currently the most successful method for
determining the three-dimensional (3D) conformation of a protein, yet it
remains labor intensive and relies on an expert's ability to derive and
evaluate a protein scene model. In this paper, the problem of protein structure
determination is formulated as an exercise in scene analysis. A computational
methodology is presented in which a 3D image of a protein is segmented into a
graph of critical points. Bayesian and certainty factor approaches are
described and used to analyze critical point graphs and identify meaningful
substructures, such as alpha-helices and beta-sheets. Results of applying the
methodologies to protein images at low and medium resolution are reported. The
research is related to approaches to representation, segmentation and
classification in vision, as well as to top-down approaches to protein
structure prediction.Comment: See http://www.jair.org/ for any accompanying file
The response of a 38m horizontal axis teetered rotor to yaw
Recent tests on the 38m Mod-0 100 kW horizontal axis experimental wind turbine yielded quantative data on the teeter response of a rotor to yaw. The test results indicate that yaw rates as high as 5 deg/s could be used in emergency situations to unload and slow a rotor for intermediate sized (500 kW) wind turbines. The results also show that teeter response is sensitive to the direction of yaw, and that teeter response to yaw is reduced as either the rotor speed or the blade lock number is increased
Development of improved structural adhesives Annual summary report, 1 Jul. 1967 - 3 Dec. 1968
Improved structural adhesives for bonding aluminum over low temperature
Experimental data and theoretical analysis of an operating 100 kW wind turbine
Experimental test data are correlated with analyses of turbine loads and complete system behavior of the ERDA-NASA 100 kW Mod-0 wind turbine generator over a broad range of steady state conditions, as well as during transient conditions. The deficit in the ambient wind field due to the upwind tower turbine support structure is found to be very significant in exciting higher harmonic loads associated with the flapping response of the blade in bending
The Use of Aerial Radiometrics for Epidemiological Studies of Leukaemia: a Preliminary Investigation in SW England
The report presents the results and conclusions of a pilot study designed to evaluate the potential use of aerial gamma ray measurements in epidemiological investigations of leukaemia. The sources of natural radiation were reviewed and associations between U, Th and K and dose to the human population noted. The association between leukaemia and radiation exposure was also noted, in particular the clear evidence from high dose studies, the potential importance of radium and radon, and the difficulties of achieving statistical significance in case-control studies at environmental dose rates due to the need for large area surveys covering large populations.
Aerial surveys were conducted in three disjoint grids selected by the Leukaemia Research Fund Clinical epidemiology unit at Leeds University. The areas covered some 2,500 km, and were surveyed in a 50 hour fieldwork period in September 1989. Over 4800 gamma spectra were recorded, representing between 200 and 400 times the number of measurements per unit area of the NRPB national maps, and an area sampling density some 106 times greater. The data were used to estimate specific activities of potassium, uranium and thorium. Environmental infinite matrix alpha and beta dose rates were calculated using equilibrium assumptions and gamma ray dose rates were estimated directly from the spectra. Mean values for gamma dose rates were compatible with NRPB estimates for the counties. The detailed gamma ray maps demonstrate that both radiation levels, and quality show local variations within each survey grid of a magnitude comparable with that observed in whole of the UK in national maps. Considerable caution is thus needed in using national data for epidemiological studies. Local variations, which can be clearly associated with underlying geological and geomorphological structures should be taken into account in such work. No significant enhancements were noted due to activities at the Devonport Dockyard, in keeping with published ground based monitoring. The main enhancement in the vicinity of Hinkley Point was due to the authorised discharge of 41Ar, which was clearly detected in the survey.
Two methods for associating the radiometric results with epidemiological data were developed and applied. A case-control study was performed by matching case and control locations to individual spatially averaged radiometric results and comparing the associated radiation levels. The second method evaluated radiation stratified incidence rates by combining stratified case radiometric data with similar information estimated from a population density surface constructed for the grids. Weighted regression analysis was used to assess any associations. The results are in general limited by the low number of leukaemia cases within the study area, resulting in statistically weak or insignificant links. However positive associations between equivalent uranium and leukaemia, particularly in the grid including the rivers Tavy and Tamar, were observed in both case-control and incidence rate analyses. A negative association with equivalent Thorium observed in the incidence rate analysis was not reproduced in case-control comparisons.
This approach could be extended to larger area studies to increase statistical power. In parallel investigations of the relationship between environmental and individual radiation exposure, and investigation of the potential association between radium, or radon and leukaemia following the trends observed here would be appropriate
Notorious places: image, reputation, stigma: the role of newspapers in area reputations for social housing estates
This paper reviews work in several disciplines to distinguish between image, reputation and stigma. It also shows that there has been little research on the process by which area reputations are established and sustained through transmission processes. This paper reports on research into the portrayal of two social housing estates in the printed media over an extended period of time (14 years). It was found that negative and mixed coverage of the estates dominated, with the amount of positive coverage being very small. By examining the way in which dominant themes were used by newspapers in respect of each estate, questions are raised about the mode of operation of the press and the communities' collective right to challenge this. By identifying the way regeneration stories are covered and the nature of the content of positive stories, lessons are drawn for programmes of area transformation. The need for social regeneration activities is identified as an important ingredient for changing deprived-area reputations
Revisiting concepts of evidence in implementation science
BACKGROUND: Evidence, in multiple forms, is a foundation of implementation science. For public health and clinical practice, evidence includes the following: type 1 evidence on etiology and burden; type 2 evidence on effectiveness of interventions; and type 3: evidence on dissemination and implementation (D&I) within context. To support a vision for development and use of evidence in D&I science that is more comprehensive and equitable (particularly for type 3 evidence), this article aims to clarify concepts of evidence, summarize ongoing debates about evidence, and provide a set of recommendations and tools/resources for addressing the how-to in filling evidence gaps most critical to advancing implementation science.
MAIN TEXT: Because current conceptualizations of evidence have been relatively narrow and insufficiently characterized in our opinion, we identify and discuss challenges and debates about the uses, usefulness, and gaps in evidence for implementation science. A set of questions is proposed to assist in determining when evidence is sufficient for dissemination and implementation. Intersecting gaps include the need to (1) reconsider how the evidence base is determined, (2) improve understanding of contextual effects on implementation, (3) sharpen the focus on health equity in how we approach and build the evidence-base, (4) conduct more policy implementation research and evaluation, and (5) learn from audience and stakeholder perspectives. We offer 15 recommendations to assist in filling these gaps and describe a set of tools for enhancing the evidence most needed in implementation science.
CONCLUSIONS: To address our recommendations, we see capacity as a necessary ingredient to shift the field\u27s approach to evidence. Capacity includes the push for implementation science where researchers are trained to develop and evaluate evidence which should be useful and feasible for implementers and reflect community or stakeholder priorities. Equally important, there has been inadequate training and too little emphasis on the pull for implementation science (e.g., training implementers, practice-based research). We suggest that funders and reviewers of research should adopt and support a more robust definition of evidence. By critically examining the evolving nature of evidence, implementation science can better fulfill its vision of facilitating widespread and equitable adoption, delivery, and sustainment of scientific advances
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