1,417 research outputs found
SDSS Standard Star Catalog for Stripe 82: the Dawn of Industrial 1% Optical Photometry
We describe a standard star catalog constructed using multiple SDSS
photometric observations (at least four per band, with a median of ten) in the
system. The catalog includes 1.01 million non-variable unresolved
objects from the equatorial stripe 82 ( 1.266) in
the RA range 20h 34m to 4h 00m, and with the corresponding band
(approximately Johnson V band) magnitudes in the range 14--22. The
distributions of measurements for individual sources demonstrate that the
photometric pipeline correctly estimates random photometric errors, which are
below 0.01 mag for stars brighter than (19.5, 20.5, 20.5, 20, 18.5) in ,
respectively (about twice as good as for individual SDSS runs). Several
independent tests of the internal consistency suggest that the spatial
variation of photometric zeropoints is not larger than 0.01 mag (rms). In
addition to being the largest available dataset with optical photometry
internally consistent at the 1% level, this catalog provides practical
definition of the SDSS photometric system. Using this catalog, we show that
photometric zeropoints for SDSS observing runs can be calibrated within nominal
uncertainty of 2% even for data obtained through 1 mag thick clouds, and
demonstrate the existence of He and H white dwarf sequences using photometric
data alone. Based on the properties of this catalog, we conclude that upcoming
large-scale optical surveys such as the Large Synoptic Survey Telescope will be
capable of delivering robust 1% photometry for billions of sources.Comment: 63 pages, 24 figures, submitted to AJ, version with correct figures
and catalog available from
http://www.astro.washington.edu/ivezic/sdss/catalogs/stripe82.htm
Cellular expression, trafficking, and function of two isoforms of human ULBP5/RAET1G
Background:
The activating immunoreceptor NKG2D is expressed on Natural Killer (NK) cells and subsets of T cells. NKG2D contributes to anti-tumour and anti-viral immune responses in vitro and in vivo. The ligands for NKG2D in humans are diverse proteins of the MIC and ULBP/RAET families that are upregulated on the surface of virally infected cells and tumours. Two splicing variants of ULBP5/RAET1G have been cloned previously, but not extensively characterised.
Methodology/Principal Findings:
We pursue a number of approaches to characterise the expression, trafficking, and function of the two isoforms of ULBP5/RAET1G. We show that both transcripts are frequently expressed in cell lines derived from epithelial cancers, and in primary breast cancers. The full-length transcript, RAET1G1, is predicted to encode a molecule with transmembrane and cytoplasmic domains that are unique amongst NKG2D ligands. Using specific anti-RAET1G1 antiserum to stain tissue microarrays we show that RAET1G1 expression is highly restricted in normal tissues. RAET1G1 was expressed at a low level in normal gastrointestinal epithelial cells in a similar pattern to MICA. Both RAET1G1 and MICA showed increased expression in the gut of patients with celiac disease. In contrast to healthy tissues the RAET1G1 antiserum stained a wide variety or different primary tumour sections. Both endogenously expressed and transfected RAET1G1 was mainly found inside the cell, with a minority of the protein reaching the cell surface. Conversely the truncated splicing variant of RAET1G2 was shown to encode a soluble molecule that could be secreted from cells. Secreted RAET1G2 was shown to downregulate NKG2D receptor expression on NK cells and hence may represent a novel tumour immune evasion strategy.
Conclusions/Significance:
We demonstrate that the expression patterns of ULBP5RAET1G are very similar to the well-characterised NKG2D ligand, MICA. However the two isoforms of ULBP5/RAET1G have very different cellular localisations that are likely to reflect unique functionality
The Milky Way Tomography With SDSS. III. Stellar Kinematics
We study Milky Way kinematics using a sample of 18.8 million main-sequence stars with r 20 degrees). We find that in the region defined by 1 kpc < Z < 5 kpc and 3 kpc < R < 13 kpc, the rotational velocity for disk stars smoothly decreases, and all three components of the velocity dispersion increase, with distance from the Galactic plane. In contrast, the velocity ellipsoid for halo stars is aligned with a spherical coordinate system and appears to be spatially invariant within the probed volume. The velocity distribution of nearby (Z < 1 kpc) K/M stars is complex, and cannot be described by a standard Schwarzschild ellipsoid. For stars in a distance-limited subsample of stars (< 100 pc), we detect a multi-modal velocity distribution consistent with that seen by HIPPARCOS. This strong non-Gaussianity significantly affects the measurements of the velocity-ellipsoid tilt and vertex deviation when using the Schwarzschild approximation. We develop and test a simple descriptive model for the overall kinematic behavior that captures these features over most of the probed volume, and can be used to search for substructure in kinematic and metallicity space. We use this model to predict further improvements in kinematic mapping of the Galaxy expected from Gaia and the Large Synoptic Survey Telescope.NSF AST-615991, AST-0707901, AST-0551161, AST-02-38683, AST-06-07634, AST-0807444, PHY05-51164NASA NAG5-13057, NAG5-13147, NNXO-8AH83GPhysics Frontier Center/Joint Institute for Nuclear Astrophysics (JINA) PHY 08-22648U.S. National Science FoundationMarie Curie Research Training Network ELSA (European Leadership in Space Astrometry) MRTN-CT-2006-033481Fermi Research Alliance, LLC, United States Department of Energy DE-AC02-07CH11359Alfred P. Sloan FoundationParticipating InstitutionsJapanese MonbukagakushoMax Planck SocietyHigher Education Funding Council for EnglandMcDonald Observator
The Milky Way Tomography with SDSS: III. Stellar Kinematics
We study Milky Way kinematics using a sample of 18.8 million main-sequence
stars with r<20 and proper-motion measurements derived from SDSS and POSS
astrometry, including ~170,000 stars with radial-velocity measurements from the
SDSS spectroscopic survey. Distances to stars are determined using a
photometric parallax relation, covering a distance range from ~100 pc to 10 kpc
over a quarter of the sky at high Galactic latitudes (|b|>20 degrees). We find
that in the region defined by 1 kpc <Z< 5 kpc and 3 kpc <R< 13 kpc, the
rotational velocity for disk stars smoothly decreases, and all three components
of the velocity dispersion increase, with distance from the Galactic plane. In
contrast, the velocity ellipsoid for halo stars is aligned with a spherical
coordinate system and appears to be spatially invariant within the probed
volume. The velocity distribution of nearby ( kpc) K/M stars is complex,
and cannot be described by a standard Schwarzschild ellipsoid. For stars in a
distance-limited subsample of stars (<100 pc), we detect a multimodal velocity
distribution consistent with that seen by HIPPARCOS. This strong
non-Gaussianity significantly affects the measurements of the velocity
ellipsoid tilt and vertex deviation when using the Schwarzschild approximation.
We develop and test a simple descriptive model for the overall kinematic
behavior that captures these features over most of the probed volume, and can
be used to search for substructure in kinematic and metallicity space. We use
this model to predict further improvements in kinematic mapping of the Galaxy
expected from Gaia and LSST.Comment: 90 pages, 26 figures, submitted to Ap
KL Estimation of the Power Spectrum Parameters from the Angular Distribution of Galaxies in Early SDSS Data
We present measurements of parameters of the 3-dimensional power spectrum of
galaxy clustering from 222 square degrees of early imaging data in the Sloan
Digital Sky Survey. The projected galaxy distribution on the sky is expanded
over a set of Karhunen-Loeve eigenfunctions, which optimize the signal-to-noise
ratio in our analysis. A maximum likelihood analysis is used to estimate
parameters that set the shape and amplitude of the 3-dimensional power
spectrum. Our best estimates are Gamma=0.188 +/- 0.04 and sigma_8L = 0.915 +/-
0.06 (statistical errors only), for a flat Universe with a cosmological
constant. We demonstrate that our measurements contain signal from scales at or
beyond the peak of the 3D power spectrum. We discuss how the results scale with
systematic uncertainties, like the radial selection function. We find that the
central values satisfy the analytically estimated scaling relation. We have
also explored the effects of evolutionary corrections, various truncations of
the KL basis, seeing, sample size and limiting magnitude. We find that the
impact of most of these uncertainties stay within the 2-sigma uncertainties of
our fiducial result.Comment: Fig 1 postscript problem correcte
Cosmological parameters from SDSS and WMAP
We measure cosmological parameters using the three-dimensional power spectrum
P(k) from over 200,000 galaxies in the Sloan Digital Sky Survey (SDSS) in
combination with WMAP and other data. Our results are consistent with a
``vanilla'' flat adiabatic Lambda-CDM model without tilt (n=1), running tilt,
tensor modes or massive neutrinos. Adding SDSS information more than halves the
WMAP-only error bars on some parameters, tightening 1 sigma constraints on the
Hubble parameter from h~0.74+0.18-0.07 to h~0.70+0.04-0.03, on the matter
density from Omega_m~0.25+/-0.10 to Omega_m~0.30+/-0.04 (1 sigma) and on
neutrino masses from <11 eV to <0.6 eV (95%). SDSS helps even more when
dropping prior assumptions about curvature, neutrinos, tensor modes and the
equation of state. Our results are in substantial agreement with the joint
analysis of WMAP and the 2dF Galaxy Redshift Survey, which is an impressive
consistency check with independent redshift survey data and analysis
techniques. In this paper, we place particular emphasis on clarifying the
physical origin of the constraints, i.e., what we do and do not know when using
different data sets and prior assumptions. For instance, dropping the
assumption that space is perfectly flat, the WMAP-only constraint on the
measured age of the Universe tightens from t0~16.3+2.3-1.8 Gyr to
t0~14.1+1.0-0.9 Gyr by adding SDSS and SN Ia data. Including tensors, running
tilt, neutrino mass and equation of state in the list of free parameters, many
constraints are still quite weak, but future cosmological measurements from
SDSS and other sources should allow these to be substantially tightened.Comment: Minor revisions to match accepted PRD version. SDSS data and ppt
figures available at http://www.hep.upenn.edu/~max/sdsspars.htm
JWST MIRI flight performance: The Medium-Resolution Spectrometer
The Medium-Resolution Spectrometer (MRS) provides one of the four operating
modes of the Mid-Infrared Instrument (MIRI) on board the James Webb Space
Telescope (JWST). The MRS is an integral field spectrometer, measuring the
spatial and spectral distributions of light across the 5-28 wavelength
range with a spectral resolving power between 3700-1300. We present the MRS's
optical, spectral, and spectro-photometric performance, as achieved in flight,
and we report on the effects that limit the instrument's ultimate sensitivity.
The MRS flight performance has been quantified using observations of stars,
planetary nebulae, and planets in our Solar System. The precision and accuracy
of this calibration was checked against celestial calibrators with well-known
flux levels and spectral features. We find that the MRS geometric calibration
has a distortion solution accuracy relative to the commanded position of 8 mas
at 5 and 23 mas at 28 . The wavelength calibration is accurate
to within 9 km/sec at 5 and 27 km/sec at 28 . The uncertainty in
the absolute spectro-photometric calibration accuracy was estimated at 5.6 +-
0.7 %. The MIRI calibration pipeline is able to suppress the amplitude of
spectral fringes to below 1.5 % for both extended and point sources across the
entire wavelength range. The MRS point spread function (PSF) is 60 % broader
than the diffraction limit along its long axis at 5 and is 15 % broader
at 28 . The MRS flight performance is found to be better than prelaunch
expectations. The MRS is one of the most subscribed observing modes of JWST and
is yielding many high-profile publications. It is currently humanity's most
powerful instrument for measuring the mid-infrared spectra of celestial sources
and is expected to continue as such for many years to come.Comment: 16 pages, 21 figure
- …