FOUR OBJECTS: A VISUAL HEARING

This thesis statement is of a two part nature. The first part shows photographs of my creative products in the process of making them and in their completed state. The second part deals with the process involved in my mental activity as these objects were created. I have presented the photographs of my work first because I feel that viewing the work before reading the text is of primary importance. Visual comprehension of my work is my major purpose. The photographs in the visual appendix are objects that exist within my world. They are abstractions. They are but a few of the things with which I am involved in my creative work. These are more than mere representations. They are my inspiration

Acceptance of shame and embarrassment:Scale development and initial findings in a clinical sample

Objectives: The ability to accept painful feelings is associated with decreased distress and better functioning. We set out to design an instrument that specifically measures acceptance of shame and embarrassment, as this may be important for the social functioning and mood of people with chronic conditions. Methods: An item set was presented to 415 non-clinical adults and to 200 people with chronic pain. Item and factor analysis were used in the creation of an instrument; the reliability and validity of this instrument were examined. Regression analysis was used to examine the ability of this instrument to predict social functioning and mood in the clinical group. Results: A 17-item unifactorial instrument was created that had good psychometric properties in both groups (theAcceptanceofShameandEmbarrassment Scale,ASES).Itcorrelatedwithothermeasuresofacceptance, and of social discomfort. It had specific predictive power in the prediction of social functioning and mood in the clinical group. Conclusions: The ASES is a reliable and valid instrument measuring the ability to accept shame and embarrassment. This ability is associated with better social functioning and mood in people with chronic pain; this form of acceptance should be targeted in treatment

Project IICE: Inspiring Interdisciplinary Collaboration Experiences

Project IICE was a multi-disciplinary learning experience designed for students at Southern New Hampshire University. Students worked together in teams to communicate scientific data that was initially collected by an Introductory Botany class. Students in this course measured trees and recorded variables, including tree height, diameter, species, and canopy cover. They shared the data with students in freshman Statistics courses, who analyzed mathematically for trends. Finally, students in Graphic Design used the data to create visual representations and icons. Students collaborated in groups that were randomly assigned across all of the courses to include members of each discipline. During the process, each student was required to help others in the group understand the meaning of the data, through the collection, analysis, and design phases. In the final group poster presentations, students explained the meaning and value of each part. The emphasis was on their ability to communicate the significance of each part of the process, which helped them appreciate how the discipline they were working in contributed to the overall success of the project. The real-world data provided a context for students to experience working in cross-discipline teams, and sharpened communication skills

Acceptance of shame and embarrassment:Scale development and initial findings in a clinical sample

Objectives: The ability to accept painful feelings is associated with decreased distress and better functioning. We set out to design an instrument that specifically measures acceptance of shame and embarrassment, as this may be important for the social functioning and mood of people with chronic conditions. Methods: An item set was presented to 415 non-clinical adults and to 200 people with chronic pain. Item and factor analysis were used in the creation of an instrument; the reliability and validity of this instrument were examined. Regression analysis was used to examine the ability of this instrument to predict social functioning and mood in the clinical group. Results: A 17-item unifactorial instrument was created that had good psychometric properties in both groups (theAcceptanceofShameandEmbarrassment Scale,ASES).Itcorrelatedwithothermeasuresofacceptance, and of social discomfort. It had specific predictive power in the prediction of social functioning and mood in the clinical group. Conclusions: The ASES is a reliable and valid instrument measuring the ability to accept shame and embarrassment. This ability is associated with better social functioning and mood in people with chronic pain; this form of acceptance should be targeted in treatment

Change in Emiliania huxleyi virus assemblage diversity but not in host genetic composition during an ocean acidification mesocosm experiment

Effects of elevated pCO2 on Emiliania huxleyi genetic diversity and the viruses that infect E. huxleyi (EhVs) have been investigated in large volume enclosures in a Norwegian fjord. Triplicate enclosures were bubbled with air enriched with CO2 to 760 ppmv whilst the other three enclosures were bubbled with air at ambient pCO2; phytoplankton growth was initiated by the addition of nitrate and phosphate. E. huxleyi was the dominant coccolithophore in all enclosures, but no difference in genetic diversity, based on DGGE analysis using primers specific to the calcium binding protein gene (gpa) were detected in any of the treatments. Chlorophyll concentrations and primary production were lower in the three elevated pCO2 treatments than in the ambient treatments. However, although coccolithophores numbers were reduced in two of the high-pCO2 treatments; in the third, there was no suppression of coccolithophores numbers, which were very similar to the three ambient treatments. In contrast, there was considerable variation in genetic diversity in the EhVs, as determined by analysis of the major capsid protein (mcp) gene. EhV diversity was much lower in the high-pCO2 treatment enclosure that did not show inhibition of E. huxleyi growth. Since virus infection is generally implicated as a major factor in terminating phytoplankton blooms, it is suggested that no study of the effect of ocean acidification in phytoplankton can be complete if it does not include an assessment of viruses

Intranasal Oxytocin Modulates Decision-Making Depending on Outcome Predictability-A Randomized Within-Subject Controlled Trial in Healthy Males.

Oxytocin (OT) has been extensively studied with regard to its socio-cognitive and -behavioral effects. Its potential as a therapeutic agent is being discussed for a range of neuropsychiatric conditions. However, there is limited evidence of its effects on non-social cognition in general and decision-making in particular, despite the importance of these functions in neuropsychiatry. Using a crossover/within-subject, blinded, randomized design, we investigated for the first time if intranasal OT (24 IU) affects decision-making differently depending on outcome predictability/ambiguity in healthy males. The Iowa Gambling Task (IGT) and the Cambridge Risk Task (CRT) were used to assess decision-making under low outcome predictability/high ambiguity and under high outcome probability/low ambiguity, respectively. After administration of OT, subjects performed worse and exhibited riskier performance in the IGT (low outcome predictability/high ambiguity), whereas they made borderline-significant less risky decisions in the CRT (high outcome probability/low ambiguity) as compared to the control condition. Decision-making in healthy males may therefore be influenced by OT and adjusted as a function of contextual information, with implications for clinical trials investigating OT in neuropsychiatric conditions

Divergent effects of oxytocin on "mind-reading" in healthy males

The online version contains supplementary material available at 10.3758/s13415-021-00936-3

Fecal microbiota transplant rescues mice from human pathogen mediated sepsis by restoring systemic immunity.

Death due to sepsis remains a persistent threat to critically ill patients confined to the intensive care unit and is characterized by colonization with multi-drug-resistant healthcare-associated pathogens. Here we report that sepsis in mice caused by a defined four-member pathogen community isolated from a patient with lethal sepsis is associated with the systemic suppression of key elements of the host transcriptome required for pathogen clearance and decreased butyrate expression. More specifically, these pathogens directly suppress interferon regulatory factor 3. Fecal microbiota transplant (FMT) reverses the course of otherwise lethal sepsis by enhancing pathogen clearance via the restoration of host immunity in an interferon regulatory factor 3-dependent manner. This protective effect is linked to the expansion of butyrate-producing Bacteroidetes. Taken together these results suggest that fecal microbiota transplantation may be a treatment option in sepsis associated with immunosuppression

Use of sonic tomography to detect and quantify wood decay in living trees.

Premise of the studyField methodology and image analysis protocols using acoustic tomography were developed and evaluated as a tool to estimate the amount of internal decay and damage of living trees, with special attention to tropical rainforest trees with irregular trunk shapes.Methods and resultsLiving trunks of a diversity of tree species in tropical rainforests in the Republic of Panama were scanned using an Argus Electronic PiCUS 3 Sonic Tomograph and evaluated for the amount and patterns of internal decay. A protocol using ImageJ analysis software was used to quantify the proportions of intact and compromised wood. The protocols provide replicable estimates of internal decay and cavities for trees of varying shapes, wood density, and bark thickness.ConclusionsSonic tomography, coupled with image analysis, provides an efficient, noninvasive approach to evaluate decay patterns and structural integrity of even irregularly shaped living trees