Applying the submission multiple tier (SMT) matrix to detect impact on developer interest on open source project survivability

© IFIP International Federation for Information Processing 2014. There is a significant relationship between project activity and developer interest on Open Source (OS) projects. Total project activity submission count number can be an indicator for gauging developer interest. The higher the project activity submission of a project is, the larger developer interest in a project. My paper proposed that applying a Submission Multiple Tier (SMT) matrix can detect the impact of developer interest on project activity. Results showed more volume of OS projects with low project activity than high. Activity submission results also showed that developers are more likely to review than correct projects, with the first priority to find and fix bugs. Further research is needed to determine the impact of project activity type on developer motivation to contribute, participate and support OS projects

Observational molecular case-control study of genetic polymorphisms 1 in programmed cell death protein-1 in patients with oral lichen planus

Background: The association between programmed cell death protein 1 (PD-1) variations and susceptibility to autoimmune diseases has been recurrently reported. However, there is no report about its relationship with oral lichen planus (OLP) as one of autoimmune diseases. Methods: We investigated the association between genetic predisposition to OLP and two single nucleotide polymorphisms in PD-1. Results: GG, GA, and AA genotypes at position +7146 were found in 59 (80.8 ), 10 (13.7 ), and 4 (5.5 ) patients, and in 132 (77 ), 34 (20 ), and 5 (3 ) healthy participants. CC, CT, and TT genotypes at position +7785 were found in 32 (43.8 ), 35 (47.9 ), and 6 (8.2 ) patients and in 99 (58 ), 66 (39 ), and 6 (3 ) controls. Analysis indicated that patients' genotypes were not statistically different from controls' genotypes at both positions +7146 (P = 0.35 and P = 0.98) and +7785 (P = 0.07 and P = 0.06). Conclusion: The findings indicated that PD-1 SNPs at +7146 PD-1.3 G/A and +7785 PD-1.5 C/T was not associated with susceptibility to OLP. However, further research with higher sample size and in different geographical regions is needed in order to achieve the generalizability of the findings. © 2019, Asian Pacific Organization for Cancer Prevention