212 research outputs found
The features of Drosophila core promoters revealed by statistical analysis
BACKGROUND: Experimental investigation of transcription is still a very labor- and time-consuming process. Only a few transcription initiation scenarios have been studied in detail. The mechanism of interaction between basal machinery and promoter, in particular core promoter elements, is not known for the majority of identified promoters. In this study, we reveal various transcription initiation mechanisms by statistical analysis of 3393 nonredundant Drosophila promoters. RESULTS: Using Drosophila-specific position-weight matrices, we identified promoters containing TATA box, Initiator, Downstream Promoter Element (DPE), and Motif Ten Element (MTE), as well as core elements discovered in Human (TFIIB Recognition Element (BRE) and Downstream Core Element (DCE)). Promoters utilizing known synergetic combinations of two core elements (TATA_Inr, Inr_MTE, Inr_DPE, and DPE_MTE) were identified. We also establish the existence of promoters with potentially novel synergetic combinations: TATA_DPE and TATA_MTE. Our analysis revealed several motifs with the features of promoter elements, including possible novel core promoter element(s). Comparison of Human and Drosophila showed consistent percentages of promoters with TATA, Inr, DPE, and synergetic combinations thereof, as well as most of the same functional and mutual positions of the core elements. No statistical evidence of MTE utilization in Human was found. Distinct nucleosome positioning in particular promoter classes was revealed. CONCLUSION: We present lists of promoters that potentially utilize the aforementioned elements/combinations. The number of these promoters is two orders of magnitude larger than the number of promoters in which transcription initiation was experimentally studied. The sequences are ready to be experimentally tested or used for further statistical analysis. The developed approach may be utilized for other species
Considerable enhancement of the critical current in a superconducting film by magnetized magnetic strip
We show that a magnetic strip on top of a superconducting strip magnetized in
a specified direction may considerably enhance the critical current in the
sample. At fixed magnetization of the magnet we observed diode effect - the
value of the critical current depends on the direction of the transport
current. We explain these effects by a influence of the nonuniform magnetic
field induced by the magnet on the current distribution in the superconducting
strip. The experiment on a hybrid Nb/Co structure confirmed the predicted
variation of the critical current with a changing value of magnetization and
direction of the transport current.Comment: 6 pages, 7 figure
Nonequilibrium phenomena in high Landau levels
Developments in the physics of 2D electron systems during the last decade
have revealed a new class of nonequilibrium phenomena in the presence of a
moderately strong magnetic field. The hallmark of these phenomena is
magnetoresistance oscillations generated by the external forces that drive the
electron system out of equilibrium. The rich set of dramatic phenomena of this
kind, discovered in high mobility semiconductor nanostructures, includes, in
particular, microwave radiation-induced resistance oscillations and
zero-resistance states, as well as Hall field-induced resistance oscillations
and associated zero-differential resistance states. We review the experimental
manifestations of these phenomena and the unified theoretical framework for
describing them in terms of a quantum kinetic equation. The survey contains
also a thorough discussion of the magnetotransport properties of 2D electrons
in the linear response regime, as well as an outlook on future directions,
including related nonequilibrium phenomena in other 2D electron systems.Comment: 60 pages, 41 figure
Quantum Size Effect transition in percolating nanocomposite films
We report on unique electronic properties in Fe-SiO2 nanocomposite thin films
in the vicinity of the percolation threshold. The electronic transport is
dominated by quantum corrections to the metallic conduction of the Infinite
Cluster (IC). At low temperature, mesoscopic effects revealed on the
conductivity, Hall effect experiments and low frequency electrical noise
(random telegraph noise and 1/f noise) strongly support the existence of a
temperature-induced Quantum Size Effect (QSE) transition in the metallic
conduction path. Below a critical temperature related to the geometrical
constriction sizes of the IC, the electronic conductivity is mainly governed by
active tunnel conductance across barriers in the metallic network. The high 1/f
noise level and the random telegraph noise are consistently explained by random
potential modulation of the barriers transmittance due to local Coulomb
charges. Our results provide evidence that a lowering of the temperature is
somehow equivalent to a decrease of the metal fraction in the vicinity of the
percolation limit.Comment: 21 pages, 8 figure
Magnetic-field-dependent zero-bias diffusive anomaly in Pb oxide-n-InAs structures: Coexistence of two- and three-dimensional states
The results of experimental and theoretical studies of zero-bias anomaly
(ZBA) in the Pb-oxide-n-InAs tunnel structures in magnetic field up to 6T are
presented. A specific feature of the structures is a coexistence of the 2D and
3D states at the Fermi energy near the semiconductor surface. The dependence of
the measured ZBA amplitude on the strength and orientation of the applied
magnetic field is in agreement with the proposed theoretical model. According
to this model, electrons tunnel into 2D states, and move diffusively in the 2D
layer, whereas the main contribution to the screening comes from 3D electrons.Comment: 8 double-column pages, REVTeX, 9 eps figures embedded with epsf,
published versio
Spectral peaks in electric field at resonance frequencies for seismically excited motion of ions in the Earth’s magnetic field
Effect of gibberellic acid (GA), indole acetic acid (IAA) and benzylaminopurine (BAP) on the synthesis of essential oils and the isomerization of methyl chavicol and trans-anethole in Ocimum gratissimum L
Strain waves, earthquakes, slow earthquakes, and afterslip in the framework of the Frenkel-Kontorova model
Actividad fitotóxica de un extracto N-Hexano obtenido de la corteza de Drimys Winteri sobre cuatro especies de malezas
- …