Demographic characteristics of participants.

<p>Demographic characteristics of participants.</p

Percentage of errors in the discrimination test.

<p>Percentage of errors in the discrimination test.</p

Scenario and percentage of errors in reading the strips during the discrimination test.

<p>Scenario and percentage of errors in reading the strips during the discrimination test.</p

Demographic data of interviewees.

<p>Demographic data of interviewees.</p

Summary of methods and objectives of the study.

<p>Summary of methods and objectives of the study.</p

Co-designed process of use of hydrophilic NG-tube and pH strips to check the tube position.

<p>Co-designed process of use of hydrophilic NG-tube and pH strips to check the tube position.</p

Visualization 3: Intraoperative measurement of bowel oxygen saturation using a multispectral imaging laparoscope

Variation of small bowel StO2 over time during euthanasia of porcine subject. Originally published in Biomedical Optics Express on 01 October 2015 (boe-6-10-4179

Visualization 2: Intraoperative measurement of bowel oxygen saturation using a multispectral imaging laparoscope

Variation of small bowel StO2 over time during clamping and unclamping of the mesenteric arcade. Originally published in Biomedical Optics Express on 01 October 2015 (boe-6-10-4179

Combining Thermal Desorption with Selected Ion Flow Tube Mass Spectrometry for Analyses of Breath Volatile Organic Compounds

An instrument integrating thermal desorption (TD) to selected ion flow tube mass spectrometry (SIFT-MS) is presented, and its application to analyze volatile organic compounds (VOCs) in human breath is demonstrated for the first time. The rationale behind this development is the need to analyze breath samples in large-scale multicenter clinical projects involving thousands of patients recruited in different hospitals. Following adapted guidelines for validating analytical techniques, we developed and validated a targeted analytical method for 21 compounds of diverse chemical class, chosen for their clinical and biological relevance. Validation has been carried out by two independent laboratories, using calibration standards and real breath samples from healthy volunteers. The merging of SIFT-MS and TD integrates the rapid analytical capabilities of SIFT-MS with the capacity to collect breath samples across multiple hospitals. Thanks to these features, the novel instrument has the potential to be easily employed in clinical practice

Thermal reaction, gradual healing and complete ablation of tumour xenograft seen <i>in vivo</i> in a mouse that received IT GNRs and CW NIR laser irradiation for three minutes.

<p>The numbering indicates the days post-irradiation while the first (un-numbered) image is the pre-irradiated tumour. The irradiated site was excised at day 30 and TEM analysis is shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0185990#pone.0185990.g010" target="_blank">Fig 10(d)–10(h)</a>.</p