Pengaruh Dukungan Suami Terhadap Kecemasan Ibu Hamil Dalam Menghadapi Persalinan Di Puskesmas Tegalrejo Yogyakarta

Dukungan suami dalam menghadapi kehamilan maupun persalinan sangat berarti, dimana suami dapat menumbuhkan rasa percaya diripada istri, sehingga mentalnya cukup kuat dalam menghadapi proses persalinan. Membantu istri dalam menyiapkan semua kebutuhan bayi, memperhatikan secara detail kebutuhan istri dan menumbuhkan rasa percaya diri serta rasa aman sehingga ibu tidak merasa cemas. (Narulita dalam Hargi, 2013).Penelitian ini bertujuan untuk mengetahui pengaruh dukungan suami terhadap kecemasan ibu hamil dalam menghadapi persalinan.Jenis penelitian ini deskriptif kuantitatif, menggunakan metode korelasional dengan rancangan cross sectional. Teknik sampling yang digunakan adalah total sampling. Jumlah sampel dalam penelitian ini adalah 40 bu hamil trimester III. Instrumen yang digunakan adalah kuesioner. Pengolahan dan analisa data menggunakan kendall tau.Hasil distibusi frekuensi dukungan suami tinggi yaitu 25 orang (52,1%). Tingkat kecemasan ibu hamil menunjukkan bahwa ibu hamil yang memiliki kecemasan sedang yaitu 17 orang (35,4%). Hasil penelitian menunjukkan nilai uji kendall tau 0,344 nilai signifikansi p-value sebesar 0,009(p<0,05).Ada hubungan antara dukungan suami dengan tingkat kecemasan ibu hamil menghadapi persalinan di Puskesmas Tegalrejo Yogyakarta dengan keeratan hubungan renda

Pengaruh Dukungan Suami Terhadap Kecemasan Ibu Hamil Dalam Menghadapi Persalinan Di Puskesmas Tegalrejo Yogyakarta

Dukungan suami dalam menghadapi kehamilan maupun persalinan sangat berarti, dimana suami dapat menumbuhkan rasa percaya diripada istri, sehingga mentalnya cukup kuat dalam menghadapi proses persalinan. Membantu istri dalam menyiapkan semua kebutuhan bayi, memperhatikan secara detail kebutuhan istri dan menumbuhkan rasa percaya diri serta rasa aman sehingga ibu tidak merasa cemas. (Narulita dalam Hargi, 2013).Penelitian ini bertujuan untuk mengetahui pengaruh dukungan suami terhadap kecemasan ibu hamil dalam menghadapi persalinan.Jenis penelitian ini deskriptif kuantitatif, menggunakan metode korelasional dengan rancangan cross sectional. Teknik sampling yang digunakan adalah total sampling. Jumlah sampel dalam penelitian ini adalah 40 bu hamil trimester III. Instrumen yang digunakan adalah kuesioner. Pengolahan dan analisa data menggunakan kendall tau.Hasil distibusi frekuensi dukungan suami tinggi yaitu 25 orang (52,1%). Tingkat kecemasan ibu hamil menunjukkan bahwa ibu hamil yang memiliki kecemasan sedang yaitu 17 orang (35,4%). Hasil penelitian menunjukkan nilai uji kendall tau 0,344 nilai signifikansi p-value sebesar 0,009(p<0,05).Ada hubungan antara dukungan suami dengan tingkat kecemasan ibu hamil menghadapi persalinan di Puskesmas Tegalrejo Yogyakarta dengan keeratan hubungan renda

Inadequate Decontamination Procedures: Sepsis Following Uneventful Endoscopy

Exogenous infection following endoscopy remains rare, however, recent attention in the media and the rise of antibacterial resistant strains of bacteria have emphasized the importance of proper sterilization techniques involved in the reprocessing of endoscopes and accessory devices. This chapter serves as comprehensive review into the epidemiology of exogenous infections as well as basic reprocessing techniques and guidelines for all medical professionals that treat patients that would benefit from endoscopy

Kingella kingae expresses type IV pili that mediate adherence to respiratory epithelial and synovial cells

Kingella kingae is a gram-negative bacterium that colonizes the respiratory tract and is a common cause of septic arthritis and osteomyelitis. Despite the increasing frequency of K. kingae disease, little is known about the mechanism by which this organism adheres to respiratory epithelium and seeds joints and bones. Previous work showed that K. kingae expresses long surface fibers that vary in surface density. In the current study, we found that these fibers are type IV pili and are necessary for efficient adherence to respiratory epithelial and synovial cells and that the number of pili expressed by the bacterium correlates with the level of adherence to synovial cells but not with the level of adherence to respiratory cells. In addition, we established that the major pilin subunit is encoded by a pilA homolog in a conserved region of the chromosome that also contains a second pilin gene and a type IV pilus accessory gene, both of which are dispensable for pilus assembly and pilus-mediated adherence. Upon examination of the K. kingae genome, we identified two genes in physically separate locations on the chromosome that encode homologs of the Neisseria PilC proteins and that have only a low level homology to each other. Examination of mutant strains revealed that both of the K. kingae PilC homologs are essential for a wild-type level of adherence to both respiratory epithelial and synovial cells. Taken together, these results demonstrate that type IV pili and the two PilC homologs play important roles in mediating K. kingae adherence

Evolutionary and functional relationships among the nontypeable Haemophilus influenzae HMW family of adhesins

Nontypeable Haemophilus influenzae (NTHi) is a common cause of localized respiratory tract disease and initiates infection by colonizing the nasopharynx. Approximately 75 to 80% of NTHi clinical isolates produce proteins that belong to the HMW family of adhesins, which are believed to facilitate colonization. The prototype HMW adhesins are designated HMW1 and HMW2 and were identified in NTHi strain 12. HMW1 and HMW2 are 71% identical and 80% similar overall, yet display differing cellular binding specificities. In the present study we set out to define more clearly the relationships between HMW1 and HMW2 and other members of the HMW family of adhesins. PCR analysis of 49 epidemiologically distinct isolates revealed that all strains possessing hmw genes as determined by Southern analysis contain two hmw loci in conserved, unlinked physical locations on the chromosome. Functional analysis of the HMW adhesins produced by three unrelated strains demonstrated that each isolate possesses one protein with HMW1-like adherence properties and another with HMW2-like adherence properties. These findings suggest that the hmw1 and hmw2 loci may have arisen via a gene duplication event in an ancestral strain. In addition, they support the hypothesis that the distinct binding specificities of HMW1 and HMW2 emerged early and have persisted over time, suggesting an ongoing selective advantage

DAN UKURAN PERUSAHAAN (SIZE) TERHADAP NILAI PERUSAHAAN DENGAN PROFITABILITAS SEBAGAI VARIABEL MODERATING

Tujuan penelitian ini adalah mengetahui Pengaruh Corporate Social Responsibility (CSR) dan Ukuran Perusahaan (Size) Terhadap Nilai Perusahaan Dengan Profitabilitas Sebagai Variabel Moderasi. Metode penelitian yang digunakan dalam penelitian ini adalah metode kuantitatif. Sedangkan populasi dalam penelitian ini adalah perusahaan manufaktur sub sektor industri dasar dan kimia yang terdaftar di Bursa Efek Indonesia (BEI) periode 2015-2019. Teknik pengambilan sampel menggunakan purposive sampling berdasarkan kriteria yang sudah ditentukan dan diperoleh sampel sebanyak 20 perusahaan. Teknik analisis yang digunakan untuk menguji hipotesis adalah analisis regresi linier berganda. Berdasarkan hasil penelitian menunjukkan bahwa Pertama, Corporate Social Responsibility (CSR) berpengaruh negatif terhadap Nilai Perusahaan. Kedua Ukuran Perusahaan berpengaruh positif terhadap Nilai Perusahaan, artinya semakin besar total aset yang dimiliki perusahaan maka akan meningkatkan nilai perusahaan. Ketiga, Profitabilitas dapat memoderasi pengaruhCSR terhadap Nilai Perusahaan, artinya kenaikan profitabilitas mampu memperkuat pengaruhCSR dalam meningkatkan Nilai Perusahaan. Keempat, Profitabilitas tidak dapat memoderasi (memperlemah) pengaruh Ukuran Perusahaan terhadap Nilai Perusahaa

The Actinobacillus pleuropneumoniae HMW1C-Like Glycosyltransferase Mediates N-Linked Glycosylation of the Haemophilus influenzae HMW1 Adhesin

The Haemophilus influenzae HMW1 adhesin is an important virulence exoprotein that is secreted via the two-partner secretion pathway and is glycosylated at multiple asparagine residues in consensus N-linked sequons. Unlike the heavily branched glycans found in eukaryotic N-linked glycoproteins, the modifying glycan structures in HMW1 are mono-hexoses or di-hexoses. Recent work demonstrated that the H. influenzae HMW1C protein is the glycosyltransferase responsible for transferring glucose and galactose to the acceptor sites of HMW1. An Actinobacillus pleuropneumoniae protein designated ApHMW1C shares high-level homology with HMW1C and has been assigned to the GT41 family, which otherwise contains only O-glycosyltransferases. In this study, we demonstrated that ApHMW1C has N-glycosyltransferase activity and is able to transfer glucose and galactose to known asparagine sites in HMW1. In addition, we found that ApHMW1C is able to complement a deficiency of HMW1C and mediate HMW1 glycosylation and adhesive activity in whole bacteria. Initial structure-function studies suggested that ApHMW1C consists of two domains, including a 15-kDa N-terminal domain and a 55-kDa C-terminal domain harboring glycosyltransferase activity. These findings suggest a new subfamily of HMW1C-like glycosyltransferases distinct from other GT41 family O-glycosyltransferases

The Haemophilus influenzae HMW1C protein is a glycosyltransferase that transfers hexose residues to asparagine sites in the HMW1 adhesin

The Haemophilus influenzae HMW1 adhesin is a high-molecular weight protein that is secreted by the bacterial two-partner secretion pathway and mediates adherence to respiratory epithelium, an essential early step in the pathogenesis of H. influenzae disease. In recent work, we discovered that HMW1 is a glycoprotein and undergoes N-linked glycosylation at multiple asparagine residues with simple hexose units rather than N-acetylated hexose units, revealing an unusual N-glycosidic linkage and suggesting a new glycosyltransferase activity. Glycosylation protects HMW1 against premature degradation during the process of secretion and facilitates HMW1 tethering to the bacterial surface, a prerequisite for HMW1-mediated adherence. In the current study, we establish that the enzyme responsible for glycosylation of HMW1 is a protein called HMW1C, which is encoded by the hmw1 gene cluster and shares homology with a group of bacterial proteins that are generally associated with two-partner secretion systems. In addition, we demonstrate that HMW1C is capable of transferring glucose and galactose to HMW1 and is also able to generate hexose-hexose bonds. Our results define a new family of bacterial glycosyltransferases

Comparative analysis of urinary schistosomiasis among primary school children and rural farmers in Obollo-Eke, Enugu State, Nigeria: Implications for control

AbstractObjectiveTo determine the prevalence, sex-age related intensity of urinary schistosomiasis and to compare such parameters among rural school children and rural farmers in selected communities in Obollo-Eke located in Southeast, Nigeria.MethodsA cross-sectional survey involving 1 337 school children and farmers was conducted in Obollo-Eke community between September 2006 and July 2007. Demographic data of subjects was collected using a questionnaire prepared for this purpose. Urine samples were collected and examined for haematuria and ova of Schistosoma haematobium (S. haematobium) using Medi-test Combi 9 and sedimentation technique respectively.ResultsThe prevalence of urinary schistosomiasis based on microscopic examination of the urine sediment for the ova of S. haematobium was 17.5% while the prevalence of haematuria was 15.6%. Infection intensity varied from light to heavy. In general, the prevalence was higher among males (20.8%) than females (14.6%; P>0.05) and was slightly higher among primary school children (18.0%; n=762) than farmers (16.9%; n=575; P>0.05). The age-specific prevalence of schistosomiasis among the study subjects ranged from 8.3% to 21.2% in 0-5 years and 11-15 years age groups respectively.ConclusionsHaematuria and mean egg/10 mL urine (r = 0.95; P<0.01) showed that both procedures are reliable for the diagnosis of the disease and can be used to ascertain the prevalence of the disease in any community. The comparative analysis of urinary bilharziasis among primary school children and rural farmers demonstrated that the infection is moderately high in these two risk population groups at Obollo-Eke. A robust intervention strategy is clearly needed

Zingiber Officinale Roscoe and Echinops Kebericho Mesfin Showed Antiplasmodial Activities against Plasmodium Berghei in a Dosedependent Manner in Ethiopia

BACKGROUND: The emergence and spread of Plasmodium falciparum resistance to antimalarial drugs necessitated the search for new drugs from natural products. Zingiber officinal Roscoe and Echinops Kebericho Mesfin are traditional herbal medicines widely used for the treatment of malaria in Ethiopia. The aim of the study was to assess the toxicity profile and in vivo antiplasmodial activities of 70% methanol crude extracts of both plant materials against Plasmodium berghei.METHODS: Healthy male Swiss Albino mice of age 4-5 weeks and weight 25-36 g were infected by P. berghei. The extracts were administered orally at doses 5000, 2500 and 1250 mg/kg for acute toxicity of E. kebericho Mesfin. Graded doses at 1000, 500 and 250 mg/kg used for four days suppressive studies. Parasitemia, body weight, packed cell volume (PCV) and survival time were determined. SPSS Version 20 was used for the analysis of data of parasitemia, body weight, PCV, and survival times. Statistical significance was determined by one-way ANOVA. Independent ttest was used to compare results. Results were presented as a mean ± standard error of the mean (M ± SEM). All data were analyzed at a 95% confidence interval (α= 0.05).RESULTS: At the dose of 5000 mg/kg, E. kebericho Mesfin showed no toxic effects. The LD50 of extract could go beyond the dose used. In vivo antiplasmodial activity of extracts showed excellent chemo suppression at 500 and 1000 mg/kg in a dose dependent manner compared with the negative control. The chemo suppressions of the 1000 mg/kg of both plant extracts were 49.53 ± 1.90% and 32.83 ± 1.03%, respectively. The survival times of P. berghei infected mice were also a dose dependent manner while failed to prevent weight loss.CONCLUSION: The extracts of both medicinal plants showed antiplasmodial activities against P. berghei. It confirmed the literature findings and their traditional uses.