10 research outputs found
Ancient reality and contemporary research. An introduction to the Conference KAINUA 2017 and its Proceedings
Introduction to the International Conference KAINUA 201
Surfactants, nanomedicines and nanocarriers: a critical evaluation on clinical trials
Advances, perspectives and innovation in drug delivery have increased in recent years; however, there is limited information available regarding the actual presence of surfactants, nanomed-icines and nanocarriers in investigational medicinal products submitted as part of a request for authorization of clinical trials, particularly for those authorized in the European Economic Area. We retrieve, analyze and report data available at the Clinical Trial Office of the Italian Medicines Agency (AIFA), increasing the transparency and availability of relevant information. An analysis of quality documentation submitted along with clinical trials authorized by the AIFA in 2018 was carried out, focusing on the key terms “surfactant”, “nanomedicine” and “nanocarrier”. Results suggest potential indications and inputs for further reflection and actions for regulators to actively and safely drive innovation from a regulatory perspective and to transpose upcoming evolution of clinical trials within a strong regulatory framework
ArchaeoBIM: dallo scavo al Building Information Modeling di una struttura sepolta. Il caso del tempio tuscanico di Uni a Marzabotto
The model of the Tuscanic Temple of Uni in Marzabotto, recently discovered, has been a common ground for engineering and archaeological studies, thanks to the processing of a Building Information Modeling (BIM). Beside the historic and archaeological analysis, the innovation of this study concerns the examination of the Etruscan temple as a three-dimensional building, with the use of technologies which impact on the architectural reliability of the model, and the design of a new method of Experimental Archaeology based on a virtual approach. The uniqueness of this approach lies in the study of original elements at the starting point of the building process, that consist in foundations or spoliated structures (i.e. negative evidences), over the clues from the historical and scientific literature. To better define this distinctive working process, the expression ArchaeoBIM has been proposed. With this expression we underline the common BIM matrix in the data management through integrated analytical models, applied to a particular aspect of the archaeological research
Stuy on dynamic interplay of STAT3-associated proteins in response to multiple activation pathways
Pharmaceutically Enhancing Medical Professionals for Difficult Conversations
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