Starshapedeness for fully-nonlinear equations in Carnot groups

In this paper we establish the starshapedness of the level sets of the capacitary potential of a large class of fully-nonlinear equations for condensers in Carnot groups, once a natural notion of starshapedness has been introduced. Our main result is Theorem 1.2 below.Comment: Accepted for publication in the Journal of the London Mathematical Societ

Starshapedeness for fully non-linear equations in Carnot groups

In this paper, we establish the starshapedness of the level sets of the capacitary potential of a large class of fully nonlinear equations for condensers in Carnot groups

The Italian mafias in the world: a systematic assessment of the mobility of criminal groups

This study complements existing literature on the mobility of criminal groups (mainly based on country case studies) with the first systematic assessment of the worldwide activities of the four main types of Italian mafias (Cosa Nostra, Camorra, ’Ndrangheta and Apulian mafias) from 2000 to 2012. Drawing from publicly available reports, a specific multiple correspondence analysis identifies the most important associations among mafias, activities, and countries. The results show that the mafias concentrate in a few countries; drug trafficking is the most frequent activity, whereas money laundering appears less important than expected; a stable mafia presence is reported in a few developed countries (mainly Germany, Canada, Australia, and the United States). The mafias show significant differences: the ’Ndrangheta tends to establish structured groups abroad, whereas the other mafias mainly participate in illicit trades

Innovative Fermented Beverages Made with Red Rice, Barley, and Buckwheat

The increase in food intolerances, allergies, and food-based lifestyle choices has dramatically increased the consumer demand for healthy foods characterized by pleasant sensory traits. In such a context, innovative cereal-based beverages are characterized by high nutritional value, pleasant palatability, and potential healthy properties. In the present study, a pool of 23 lactic acid bacteria strains was preliminary assayed as monocultures for the fermentation of three ad hoc formulated cereal- (red rice and barley) and pseudocereal (buckwheat) -based substrates. Eight strains with the best performance in terms of acidification rate were selected for the formulation of three multiple strain cultures to be further exploited for the manufacture of laboratory-scale prototypes of fermented beverages. The compositional and microbiological features of the three experimental beverages highlighted their high biological value for further exploitation

Cardiovascular flukes (Trematoda: Spirorchiidae) in Caretta caretta Linnaeus, 1758 from the Mediterranean Sea

Background: The northern Adriatic Sea represents one of the most important neritic foraging grounds for the loggerhead sea turtle Caretta caretta L. in the Mediterranean Sea. Four genera of blood flukes with variable prevalence and pathogenic impact have been reported worldwide in this species. Hapalotrema Looss, 1899 and Amphiorchis Price, 1934 are the only two genera reported in Mediterranean waters; however, updated data describing spirorchiidiasis in the central and eastern Mediterranean and infection prevalence are still lacking. This work aimed to investigate the presence and pathology of spirorchiidiasis in C. caretta in the Mediterranean Sea. Methods: One hundred sixty-eight animals stranded along the northwestern Adriatic coast between 2009 and 2015 were submitted to necropsy and subsequent analyses for the detection of adult flukes, detection of eggs in the faeces and spleen and histopathology. Molecular analyses were carried out on hosts (mitochondrial D-loop) and parasites (28S gene and ITS2 spacer) to trace the turtle origins and identify the fluke phylogenetic relationships. Results: Spirorchiidiasis was detected in 16.7% of the animals. Hapalotrema mistroides (Monticelli, 1899) and Neospirorchis sp. were found in twenty-six and ten cases, respectively. Adult flukes were found in six cases, while eggs were detectable through copromicroscopic examination for all infected turtles, and the results for the detection of eggs in the spleen agreed with the copromicroscopic analysis. Only mild lesions were observed. Eggs of types 1 and 3 were grossly visible in the gastrointestinal mucosa, vasculitis was rarely observed in the heart and great vessels, and multifocal granulomas were widespread in the tissues. Molecular identification unambiguously assigned the spirorchiid samples to H. mistroides and Neospirorchis sp. Genetic characterization of loggerhead mtDNA pointed to a Mediterranean origin of the turtle hosts. Conclusion: This survey provides new data on the spread of spirorchiidiasis in the Mediterranean loggerhead sea turtle population and reports for the first time the presence of Neospirorchis spp. in this basin. The infections did not have a causal effect on the death nor a strong impact on the general health status of the animals

Physical PEGylation to Prevent Insulin Fibrillation

Insulin is one of the most marketed therapeutic proteins worldwide. However, its formulation suffers from fibrillation, which affects the long-term storage limiting the development of novel devices for sustained delivery including portable infusion devices. We have investigated the effect of physical PEGylation on structural and colloidal stability of insulin by using 2 PEGylating agents terminating with polycyclic hydrophobic moieties, cholane and cholesterol: mPEG5kDa-cholane and mPEG5kDa-cholesterol, respectively. Microcalorimetric analyses showed that mPEG5kDa-cholane and mPEG5kDa-cholesterol efficiently bind insulin with binding constants (Ka) of 3.98 104 and 1.14 105 M-1, respectively. At room temperature, the 2 PEGylating agents yielded comparable structural stabilization of \u3b1-helix conformation and decreased dimerization of insulin. However, melting studies showed that mPEG5kDa-cholesterol has superior stabilizing effect of the protein conformation than mPEG5kDa-cholane. Furthermore, the fibrillation study showed that at a 1:1 and 1:5 insulin/polymer molar ratios, mPEG5kDa-cholesterol delays insulin fibrillation 40% and 26% more efficiently, respectively, as compared to mPEG5kDa-cholane which was confirmed by transmission electron microscopy imaging. Insulin was released from the mPEG5kDa-cholane and mPEG5kDa-cholesterol assemblies with comparable kinetic profiles. The physical PEGylation has a beneficial effect on the stabilization and shielding of the insulin structure into the monomeric form, which is not prone to fibrillation and aggregation

Sicilia austriaca 1720-1734

From 1720 to 1734, the island of Sicily was under the control of the Austrian Habsburgs. The political and historical aspects of this brief period have been the subject of a number of studies, which have established the necessary foundation to pursue new prospects and directions for further scholarship. However, our understanding of the range of artistic and architectural interventions undertaken – or hypothetically undertaken – by the Austrian Habsburg government in Sicily is drastically more limited. If direct commissions, travels, architects' and aristocrats' mobility to the Viennese court and even documented contacts constitute a first degree of evidence, a further field is linked to the dissemination of books and prints. In both cases, the information that has emerged is likely the tip of a larger iceberg, which can provide insights that go beyond the primary stage of "influence", as the texts of this catalogue show. The catalogue is organized thematically. The first part deals with architecture produced for the court or related to commissions by Austrian oaicers; the second part, entitled “Architecture of Reverence”, relates to commissions and architectural solutions that, formally or symbolically, indicate an affinity. In all cases, the medium of digital drawing played a fundamental role in research, giving the theme comprehensible and appropriate representation

A fundamental solution for a subelliptic operator in finsler geometry

We introduce a class of nonlinear partial differential equations in a product space which are at the interface of Finsler and sub-Riemannian geometry. To such equations we associate a non-isotropic Minkowski gauge Θ for which we introduce a suitable notion of Legendre transform Θ . We compute the action of the relevant nonlinear PDEs on “radial” functions, i.e., functions of Θ0, and by exploiting it we are able to compute explicit fundamental solutions of such PDEs

Children with autistic spectrum disorder can imagine actions— what can this reveal about the Broken Mirror Hypothesis?

Objective: This study investigated whether children with Autistic Spectrum Disorder (ASD) can imagine object directed actions similarly to their typically developed (TD) peers. Study design: We tested the ability to imagine goal directed actions in children with ASD (n = 18) and TD (n = 18) peers by means of VMIQ-2 questionnaire and a novel behavioral task, in which children were requested to imagine some daily actions, after seeing them through videoclips presented on a computer screen. Observed actions lasted 4 s and children were requested to follow the same time course during imagination. During this motor imagery (MI) task, children were interrupted at a specific timepoint (e.g., at 1.5 s) from the beginning of the task. Afterwards, they had to select one of two frames extracted from the videoclips: one showed the correct timepoint at which the imagined action was stopped, the other depicted an earlier or later timepoint. Children had to press the key associated to the correct frame to provide their responses. Results: Both groups performed similarly in the questionnaire and in the novel MI task, where they showed the same error rate. Errors distribution suggests that all children exploited a similar strategy to solve the task, being errors mainly distributed in judging the later frame. Conclusion: These findings support the view that children with ASD can imagine actions similarly to their TD peers. These results do not fully support the Broken Mirror Hypothesis and may encourage the use of MI as a cognitive strategy in the rehabilitation of autism

Counterfeiting, illegal firearms, gambling and waste management: an exploratory estimation of four criminal markets

This article focuses on four different criminal markets: counterfeiting, illegal firearms trafficking, gambling and waste management. Despite recurrent allegations that these markets have a high mafia presence, there is a lack of reliable estimates of their sizes and the revenues that they generate. Figures in reports and media vary significantly, and the methods used to obtain them are often obscure. This study develops four different estimation methodologies with which to estimate the four criminal markets in Italy at the national and regional levels. Considering that these are the first attempts to estimate these markets, the aim of the article is to stimulate debate on how to improve measurement of the crime proceeds from these criminal market