HySEA model verification for Tohoku 2011 Tsunami. Application for mitigation tsunami assessment

In many aspects Tohoku-Oki 2011 mega tsunami has changed our perception of tsunami risk. The tsunami-HySEA model is used to numerically simulate this event and observed data will we used to verify the model results. Three nested meshes of enhanced resolution (4 arc-min, 32 arc-sec and 2 arc-sec) will be used by the numerical model. The propagation mesh covers all Pacific Ocean with more of 7 million cells. An intermediate mesh with 5 millions cells contains the Japanese archipelago and, finally, two finer meshes, with nearly 8 and 6 millions cells, cover Iwate and Miyagi Prefectures at Tohoku region, the most devastated areas hit by the tsunami. The presentation will focus on the impact of the tsunami wave in these two areas and comparisons with observed data will be performed. DART buoys time series, inundation area and observed runup is used to assess model performance. The arrival time of the leading flooding wave at the vicinity of the Senday airport, as recorded by video cameras, is also used as verification data for the model. After this tsunami, control forests as well as breakwaters has been discussed as suitable mitigation infrastructures. As particular case, we will analyse the evolution of the tsunami in the area around the Sendai airport (Miyagi Prefecture) and its impact on the airport. A second simulation has been performed, assuming the existence of a coastal barrier protecting the area. The role of this barrier in modifying tsunami wave evolution and mitigating flooding effects on the airport area are discussed. The protection effect of the breakwaters near Kamaishi (Iwate Prefecture) is also assessed. The numerical model shows how these structures, although did not provide a full protection to tsunami waves, they helped to largely mitigate its effects in the area.Acknowledgements. This research has been partially supported by the Junta de Andalucía research project TESELA (P11-RNM7069), the Spanish Government Research project DAIFLUID (MTM2012-38383-C02-01) and Universidad de Málaga, Campus de Excelencia Internacional Andalucía Tech. The multi-GPU computations were performed at the Laboratory of Numerical Methods (University of Malaga)

La lúdica como estrategia para fomentar valores en la convivencia escolar

The purpose of this study was to analyze play as a strategy to promote values in school life in the second grade A of the Escuela Normal Superior del Distrito de Barranquilla. The type of research is qualitative and the paradigm is socio-critical, which allowed to generate a social change in I.E. This research allowed to implement didactic strategies that allowed to improve the behaviors of the students of second in the school coexistence, allowing to be change generators to promote healthy school climate environments. We also show the relevance of the teaching strategy in response to the problem raised. From the theoretical bases by Martinez (2012), Jiménez (2008), Parra (2004), Martinelli (2008), among others, which allowed us to support our theoretical and conceptual framework. As a result of the pedagogical strategy implemented, the physical and verbal aggressions in the students were reduced, allowing them to exercise their basic principles in order to improve their perception of school life.El presente estudio tuvo como propósito analizar la lúdica como estrategia para fomentar valores en la convivencia escolar en el grado segundo A de la Escuela Normal Superior del Distrito de Barranquilla. El tipo de investigación es cualitativa y el paradigma es sociocritico, lo cual permitió generar un cambio social en la Institución educativa. Esta investigación permitió implementar estrategias didácticas que permitieron mejorar las conductas de los estudiantes de segundo A en la convivencia escolar, ser generadores de cambio para promover ambientes de clima escolar sanos. Asimismo, evidenciamos la pertinencia de la estrategia de enseñanza dando respuesta a la problemática planteada. Desde las bases teóricas por Martínez (2012), Jiménez (2008), Parra (2004), Martinelli (2008), entre otros, permitieron sustentar nuestro marco teórico y conceptual. Como resultado de la estrategia pedagógica implementada se logró disminuir las agresiones físicas y verbales en los estudiantes permitiendo ejercer sus principios básicos con el fin de mejorar la percepción que tenían de la convivencia escolar

Evaluation of the bioaccessibility of antioxidant bioactive compounds and minerals of four genotypes of Brassicaceae microgreens

Microgreens constitute an emerging class of fresh, healthy foods due to their nutritional composition. In this study the content of minerals and antioxidant bioactive compounds, and for the first time bioaccessibility, were evaluated in broccoli (Brassica oleracea L. var. italica Plenck), green curly kale (Brassica oleracea var. sabellica L.), red mustard (Brassica juncea (L.) Czern.) and radish (Raphanus sativus L.) hydroponic microgreens. Macro- (K, Ca, Mg) and oligo-elements (Fe, Zn), ascorbic acid, total soluble polyphenols, total carotenoids, total anthocyanins, total isothiocyanates and total antioxidant capacity (Trolox Equivalent Antioxidant Capacity and Oxygen Radical Absorbance Capacity) were determined before and after the standardized simulated gastrointestinal digestion process. All microgreens provided relevant amounts of vitamin C (31-56 mg/100 g fresh weight) and total carotenoids (162-224 mg β-carotene/100 g dry weight). Mineral content was comparable to that normally found in hydroponic microgreens and the low potassium levels observed would allow their dietetic recommendation for patients with impaired kidney function. Both total soluble polyphenols and total isothiocyanates were the greatest contributors to the total antioxidant capacity after digestion (43-70% and 31-63% bioaccessibility, respectively) while macroelements showed an important bioaccessibility (34-90%). In general, radish and mustard presented the highest bioaccessibility of bioactive compounds and minerals. Overall, the four hydroponic Brassicaceae microgreens present a wide array of antioxidant bioactive compounds

Ca2 + Dynamics in chemoreceptor cells: an overview

Producción CientíficaThe carotid body (CB) was defined as a sensory organ by De Castro in 1928. Two years later, Heymanns and coworkers demostrated that the organ was sensitive to alterations in blood gases and pH, in such a way that a decrease in blood P02 or pH or an increase in blood PC02 produced activation of the CB and, reflexely, hyperventilation. De Castro postulated that glomus cells were the sensor structures and that they should release sorn substance to transmit the stimulus to the sensory nerve endings (De Castro, 1928). De Castro's point of view, was widely accepted, and therefore the CB was considered a secondary sensory receptor. As a consequence, the principal aims of many workers in the chemoreception field have been to define the nature of the sensing mechanims ( sensory transduction process ) and to identify the substances released by chern cells

Resultados de la reparación quirúrgica Del ligamento deltoideo en las fracturas equivalentes bimaleolares

ObjetivoEl objetivo de este estudio es evaluar los resultados de la reparación quirúrgica del ligamento deltoideo en fracturas equivalente bimaleolares.Material y métodoEntre 2002 y 2009 fueron intervenidos 49 pacientes con fractura del maléolo peroneo y signos clásicos de lesión del ligamento deltoideo; finalmente se recuperaron para la revisión 44 pacientes. Se dividieron en 2 grupos: grupo A con 33 casos, en los que se reparó el ligamento deltoideo, y grupo B con 11 casos, donde el deltoideo fue tratado conservadoramente. Las fracturas fueron clasificadas según Lauge-Hansen y la AO/OTA. Para la valoración clínico-funcional se usó la escala de la American Orthopaedic Foot and Ankle Society (AOFAS) para el tobillo. Se registraron las complicaciones y reintervenciones.ResultadosTras un seguimiento medio de 12 meses, se obtuvo un resultado satisfactorio en ambos grupos, con una puntuación media final de 95 puntos en el grupo A y una de 94 en el grupo B, según la escala AOFAS. Hubo 2 infecciones, 1 intolerancia de la sutura medial, 1 algodistrofia y 4 casos precisaron retirada de material.ConclusionesNuestros resultados sugieren que la lesión del ligamento deltoideo puede ser reparada con buenos resultados funcionales. Y entendemos que, aunque los signos clásicos nos ayudan a sospechar la lesión, no son predictores fiables de la necesidad de reparación del lado medial.PurposeThe purpose of this study is to evaluate the result of surgical repair of deltoid ligament in fracture of the distal fibula upper or at the syndesmotic level.Materials and methodsBetween 2002 and 2009, 49 patients with distal fibula fractures and classical signs of deltoid ligament incompetence were operated, 44 were available for follow-up. Two groups: group A included 33 cases in whom deltoid ligament was treated by surgical repair, and group B, 11 cases who were treated conservatively. All fractures were classified according to Lauge-Hansen and AO/OTA. The AOFAS ankle score was used for clinical and functional evaluation. Complications and reinterventions were recorded.ResultsAt a mean follow-up of 12 months, a satisfactory functional result was obtained in both groups, with a mean final score of 95 points in group A and 94 in group B on the AOFAS scale. There were 2 infection, a medial suture intolerance, an algodystrophy and 4 hardware removed.ConclusionsOur findings suggest that a ruptured deltoid ligament can be repair with goods functional result. And we understand that although the classical signs help us to suspect a torn ligament, are not reliable predictors for surgical revision of the medial side

Adaptación de asignaturas seleccionadas de la titulación de Logopedia a créditos ETCS. Implicaciones del alumnado

Producción CientíficaSe presenta una primera experiencia práctica en el marco del proceso de Convergencia Europea de la enseñanza. El proyecto nace con el objetivo de adaptar asignaturas seleccionadas del actual plan de estudios de la Titulación (Diplomatura) de Logopedia al reciente “Sistema de Transferencia de Créditos Europeos” (créditos ECTS o European Credit Transfer System). Con este fin se crea una red de carácter nacional en la que participan la Universidad de Valladolid, Salamanca y Castilla-La Mancha. En la presente comunicación se explican de forma exhaustiva diversos aspectos relacionados con la elaboración del proyecto: selección de asignaturas, implicación de profesorado y alumnado, así como la programación de actividades y acciones que se están llevando a cabo actualmente

Spread of streptococcus pneumoniae serotype 8-ST63 multidrug-resistant recombinant clone, Spain

Since 2004, a total of 131 isolates of Streptococcus pneumoniae multidrug-resistant invasive serotype 8 have been detected in Spain. These isolates showed resistance to erythromycin, clindamycin, tetracycline, and ciprofloxacin. All isolates were obtained from adult patients and shared a common genotype (sequence type [ST]63; penicillin-binding protein 1a [pbp1a], pbp2b, and pbp2x gene profiles; ermB and tetM genes; and a ParC-S79F change). Sixty-eight isolates that required a ciprofloxacin MIC ≥16 μg/mL had additional gyrA gene changes. Serotype 8-ST63 pbp2x sequences were identical with those of antimicrobial drug-susceptible serotype 8-ST53 isolates. Serotype 8-ST63 pbp2b sequences were identical with those of the multidrug-resistant Sweden 15A-ST63 clone. Recombination between the capsular locus and flanking regions of an ST53 isolate (donor) and an ST63 pneumococcus (recipient) generated the novel 15A-ST63 clone. One recombination point was upstream of pbp2x and another was within pbp1a. A serotype 8-ST63 clone was identified as a cause of invasive disease in Spain

A mixture of algae and extra virgin olive oils attenuates the cardiometabolic alterations associated with aging in male wistar rats

Aging is one of the major risk factors for suffering cardiovascular and metabolic diseases. Due to the increase in life expectancy, there is a strong interest in the search for anti-aging strategies to treat and prevent these aging-induced disorders. Both omega 3 polyunsaturated fatty acids (ω-3 PUFA) and extra virgin olive oil (EVOO) exert numerous metabolic and cardiovascular benefits in the elderly. In addition, EVOO constitutes an interesting ingredient to stabilize ω-3 PUFA and decrease their oxidation process due to its high content in antioxidant compounds. ω-3 PUFA are commonly obtained from fish. However, more ecological and sustainable sources, such as algae oil (AO) can also be used. In this study, we aimed to study the possible beneficial effect of an oil mixture composed by EVOO (75%) and AO (25%) rich in ω-3 PUFA (35% docosahexaenoic acid (DHA) and 20% eicosapentaenoic acid (EPA)) on the cardiometabolic alterations associated with aging. For this purpose; young (three months old) and old (24 months old) male Wistar rats were treated with vehicle or with the oil mixture (2.5 mL/kg) for 21 days. Treatment with the oil mixture prevented the aging-induced increase in the serum levels of saturated fatty acids (SFA) and the aging-induced decrease in the serum concentrations of mono-unsaturated fatty acids (MUFA). Old treated rats showed increased serum concentrations of EPA and DHA and decreased HOMA-IR index and circulating levels of total cholesterol, insulin and IL-6. Treatment with the oil mixture increased the mRNA levels of antioxidant and insulin sensitivity-related enzymes, as well as reduced the gene expression of pro-inflammatory markers in the liver and in cardiac and aortic tissues. In addition, the treatment also prevented the aging-induced endothelial dysfunction and vascular insulin resistance through activation of the PI3K/Akt pathway. Moreover, aortic rings from old rats treated with the oil mixture showed a decreased response to the vasoconstrictor AngII. In conclusion, treatment with a mixture of EVOO and AO improves the lipid profile, insulin sensitivity and vascular function in aged rats and decreases aging-induced inflammation and oxidative stress in the liver, and in the cardiovascular system. Thus, it could be an interesting strategy to deal with cardiometabolic alterations associated with aging.This project was funded by the call “Doctorados Industriales 2017” (IND2017/BIO7701), a grant from Community of Madrid (Spain). This program aims to promote the effective collaboration between Universities and Companies and provides funding for the development of the research project at the University and, to hire a PhD student (Daniel González-Hedström) by the Company (Pharmactive Biotech Products S.L.) over a three-year period. Community of Madrid also funded the contract of María de la Fuente-Fernández through the Youth Employment Program (PEJ-2018-AI/SAL-11315

Cumplimiento de intervenciones de enfermería para el mantenimiento del catéter venoso central en pacientes pediátricos

Introducción: El catéter venoso central es necesario en los cuidados pediátricos, sin embargo, es una causa importante de bacteriemia nosocomial con 25% de mortandad. El profesional de enfermería es responsable del mantenimiento del catéter venoso central con el propósito de evitar complicaciones locales y sistémicas como la endocarditis y la bacteriemia relacionadas al tratamiento endovenoso.Objetivo: Describir las intervenciones de enfermería para el mantenimiento del catéter venoso central en pacientes pediátricos de un hospital especializado.Metodología: Diseño observacional, descriptivo, transversal, muestra conformada por 85 profesionales de enfermería que otorgaron cuidados directos a niños hospitalizados y recibieron capacitación, muestreo no probabilístico, el instrumento utilizado fue una lista de verificación de mantenimiento del catéter venoso central. Se recolectaron datos con la técnica de observación. El estudio cumple con los aspectos éticos de la ley general de salud en materia de investigación.Resultados: Las intervenciones de enfermería se realizaron con un cumplimiento global de 90.1%, se enfatiza que 70.6% efectuaron lavado de manos antes de manipular el dispositivo. La limpieza y mantenimiento del sitio de inserción la realizaron 98.8%, desinfectaron puertos y conexiones, identificaron lúmenes 92.9%.Conclusión: Los profesionales de enfermería realizan las intervenciones para el mantenimiento del catéter venoso central con un cumplimiento bueno. Sin embargo, las intervenciones con menor cumplimiento que requieren mejora son la higiene de manos, los tiempos para cambios de equipo y soluciones, la desinfección de puertos y conexiones; esenciales para disminuir las infecciones del torrente sanguíneo. Además de estudios futuros acerca de los factores profesionales e institucionales asociados al cumplimiento

Utilización de la plataforma "Intact" para el diseño de materiales didácticos que faciliten la construcción significativa compartida del conocimiento desde la asignatura del practicum de magisterio y educación social

Intact es una plataforma virtual producto del Proyecto multilateral Comenius (Nº 527932-LLP-1-2012-1-DE-COMENIUS-CMP) en el que participaron algunos de los profesores implicados en el presente proyecto de innovación. La filosofía de esta plataforma virtual era crear un espacio que permitiera a los docentes compartir materiales al estilo web 2.0. Como formadores de formadores, queremos dar continuidad a esta filosofía de trabajo basada en la cooperación empezando desde la base, es decir, desde la asignatura Prácticum III del plan de formación de maestros y educadores sociales. La propuesta no se centra en el uso de esta plataforma, -que de hecho ha sido sustituida por la plataforma Moodle de la UCM al adaptarse esta mejor esta plataforma a nuestras necesidades docentes- , sino potenciar el diálogo y el aprendizaje cooperativo como base para un aprendizaje significativo y crítico, garantía de una buena formación profesionalizante. Esta filosofía de trabajo cooperativo se ha querido desarrollar en tres líneas de acción: entre los estudiantes de prácticas, futuros profesores, esperando que esta filosofía “arraigue” en ellos y continúen fomentándola en el desarrollo de su ejercicio profesional; entre los mentores de prácticas (profesores de aula en los centros), confiando que estos se contagien – si no son todavía defensores de este enfoque-; y entre los estudiantes propiamente dichos (los de los centros de prácticas). El desarrollo práctico se ha centrado en la realización de reuniones, presenciales y virtuales y en el diseño y participación en foros cooperativos