Psychosocial Variables and Healthcare Resources in Patients with Fibromyalgia, Migraine and Comorbid Fibromyalgia and Migraine: A Cross-Sectional Study

Fibromyalgia and migraine frequently coexist. We aimed to compare the burden caused by fibromyalgia (FM), migraine (M) and comorbid fibromyalgia and migraine (FM + M) by assessing psychosocial variables and the use of healthcare resources. A survey was posted to the websites of different patients' associations. It included sociodemographic data, the Patient Health Questionnaire-9, the Insomnia Severity Index, the EuroQOL-5D-5L and a questionnaire evaluating the use of healthcare resources during the past six months. In total, 139 FM patients, 169 M patients and 148 FM + M patients participated in the survey. Mean depression and insomnia scores were clinically relevant in every group and significantly higher in FM + M (16.3 +/- 5.4 for depression, 18.5 +/- 5.6 for insomnia) than in FM (14.3 +/- 5.7 for depression, 16.8 +/- 5.5 for insomnia) or M (11.7 +/- 5.4 for depression, 13.1 +/- 5.9 for depression), where p < 0.001 in both cases. Suicidal ideation was frequent in every group, but significantly more frequent in FM + M (63% vs. 45% in FM and 35% in M; p < 0.001). EQ-5D-5L (0.656 +/- 0.1 in FM + M, 0.674 +/- 0.1 in FM, 0.827 +/- 0.1 in M, p < 0.001) and EQ-5D-5L VAS scores (38.2 +/- 21.9 in FM + M, 45.6 +/- 21.8 in FM, 63.5 +/- 23.7 in M, p < 0.00) were lower than the reported mean population values and the lowest in FM + M. FM and FM + M used more healthcare resources than M. It is concluded that the psychosocial burden was high in the three samples. FM and FM + M had a more relevant impact on patients' wellbeing and required more medical attention than M. The burden caused by FM + M was higher than in both individual diseases

Experience moderation effect on the relationship between usefulness, ease of use and website acceptance

The modelling of acceptance behaviour of new information technologies is of great utility to managers who need to evaluate the probability of success in the introduction of these technologies. The present study empirically tests the capacity of Fishbein and Ajzen´s Theory of Reasoned Action (TRA) (1975) and Davis´s Technology Ac-ceptance Model (TAM) (1989) to help understand the determinants of the intention to revisit a website – ease of use and perceived usefulness – focusing on the experience moderation effect. The findings show that a combination of both theories explains the acceptance of a website by Internet users. Furthermore, within the effect of each of the elements of TAM, the user’s experience of the website plays a moderating role. In this regard, ease of use is a more important factor in determining a furure revisit to a website in the case of the less experienced users, while perceived usefulness is a more influential factor in the case of the high experience users

Validation of a Spanish version of the Revised Fibromyalgia Impact Questionnaire (FIQR)

8 p.[EN]The Revised version of the Fibromyalgia Background The Revised version of the Fibromyalgia Impact Questionnaire (FIQR) was published in 2009. The aim of this study was to prepare a Spanish version, and to assess its psychometric properties in a sample of patients with fibromyalgia. Methods The FIQR was translated into Spanish and administered, along with the FIQ, the Hospital Anxiety Depression Scale (HADS), the 36-Item Short-Form Health Survey (SF-36), and the Brief Pain Inventory (BPI), to 113 Spanish fibromyalgia patients. The administration of the Spanish FIQR was repeated a week later. Results The Spanish FIQR had high internal consistency (Cronbach’s α was 0.91 and 0.95 at visits 1 and 2 respectively). The test-retest reliability was good for the FIQR total score and its function and symptoms domains (intraclass correlation coefficient (ICC > 0.70), but modest for the overall impact domain (ICC = 0.51). Statistically significant correlations (p < 0.05) were also found between the FIQR and the FIQ scores, as well as between the FIQR scores and the remaining scales’ scores. Conclusions The Spanish version of the FIQR has a good internal consistency and our findings support its validity for assessing fibromyalgia patients. It might be a valid instrument to apply in clinical and investigational grounds.[ES]Antecedentes El Cuestionario de Impacto de Fibromialgia (FIQ) ha sido utilizado como medida de valoración en numerosos estudios clínicos. En 2009 se publicó en inglés su versión revisada (FIQR). El presente estudio se llevó a cabo para traducir al español y validar dicha versión. Pacientes y Método La traducción fue realizada por dos de los autores. La versión traducida del FIQR se administró a 113 pacientes con fibromialgia junto con el FIQ, la Escala Hospitalaria de Ansiedad y Depresión, el Cuestionario de Salud SF-36 y la versión abreviada del Cuestionario Breve de Dolor. Una semana después se administró de nuevo el FIQR. Su consistencia interna se evaluó mediante el coeficiente α de Cronbach. Se calcularon los coeficientes de correlación intraclase (ICC) entre las puntaciones de la nueva versión y la anterior, así como las subescalas del Cuestionario SF-36, de la Escala Hospitalaria de Ansiedad y Depresión y del Inventario Breve de Dolor. La fiabilidad test-retest se evaluó igualmente mediante coeficientes de correlación intraclase. Resultados El coeficiente α de Cronbach de la versión en estudio fue elevado (0,91 en la primera visita y de 0,95 en la segunda). La fiabilidad test-retest fue buena para la puntuación total del FIQR y para las dimensiones de función y síntomas ( ICC ≥ 0,70) pero modesta para la dimensión de impacto global (ICC = 0,51). Asimismo se encontraron coeficientes de correlación elevados y estadísticamente significativos respecto a las restantes escalas aplicadas (p < 0,05). Conclusión La versión española del FIQR es un instrumento válido para su uso en la evaluación e investigación clínicas

Suicidal ideation and the risk of suicide in patients with fibromyalgia: a comparison with non-pain controls and patients suffering from low-back pain

Fibromyalgia is associated with an increased rate of mortality from suicide. In fact, this disease is associated with several characteristics that are linked to an increased risk of suicidal behaviors, such as being female and experiencing chronic pain, psychological distress, and sleep disturbances. However, the literature concerning suicidal behaviors and their risk factors in fibromyalgia is sparse. The objectives of the present study were to evaluate the prevalence of suicidal ideation and the risk of suicide in a sample of patients with fibromyalgia compared with a sample of healthy subjects and a sample of patients with chronic low-back pain. We also aimed to evaluate the relevance of pain intensity, depression, and sleep quality as variables related to suicidal ideation and risks. Logistic regression was applied to estimate the likelihood of suicidal ideation and the risk of suicide adjusted by age and sex. We also used two logistic regression models using age, sex, pain severity score, depression severity, sleep quality, and disease state as independent variables and using the control group as a reference. Forty-four patients with fibromyalgia, 32 patients with low-back pain, and 50 controls were included. Suicidal ideation, measured with item 9 of the Beck Depression Inventory, was almost absent among the controls and was low among patients with low-back pain; however, suicidal ideation was prominent among patients with fibromyalgia (P,0.0001). The risk of suicide, measured with the Plutchik Suicide Risk Scale, was also higher among patients with fibromyalgia than in patients with low-back pain or in controls (P,0.0001). The likelihood for suicidal ideation and the risk of suicide were higher among patients with fibromyalgia (odds ratios of 26.9 and 48.0, respectively) than in patients with low-back pain (odds ratios 4.6 and 4.7, respectively). Depression was the only factor associated with suicidal ideation or the risk of suicide

Propiedades psicométricas de la versión en español del Cuestionario de Necesidades Interpersonales de 12 ítems en pacientes con síndrome de fibromialgia.

Según la teoría interpersonal del suicidio, la pertenencia frustrada y la carga percibida son elementos clave en el desarrollo de la ideación suicida. El Cuestionario de necesidades interpersonales (INQ) fue diseñado para evaluar el grado de frustración de estas dos necesidades interpersonales relacionadas con la ideación suicida. El objetivo de este estudio fue analizar las propiedades psicométricas de una adaptación al español del INQ-12 en pacientes con fibromialgia. Un análisis factorial exploratorio (n = 180) y un análisis factorial confirmatorio (n = 179) fueron realizados en dos submuestras seleccionadas al azar. El primer análisis llevó a la eliminación de dos ítems, mientras que el segundo confirmó el ajuste de la estructura propuesta de dos factores. La fiabilidad estimada mediante el coeficiente alfa de Cronbach y el coeficiente Spearman-Brown fue adecuada. Para obtener evidencias de validez basadas en la relación con otros variables, se utilizaron tres variables relacionadas con el suicidio. Además, se utilizó un grupo control (n = 99) para contrastar los promedios de las puntuaciones INQ como evidencia de validez basada en puntajes diferenciales. Estos hallazgos respaldan la utilidad de la versión española del INQ-10 para evaluar el grado de frustración de estas necesidades interpersonales en pacientes con fibromialgia.According to the interpersonal theory of suicide, thwarted belongingness and perceived burdensomeness are key elements in the development of suicidal ideation. The Interpersonal Needs Questionnaire (INQ) was developed to assess the degree of frustration of these two interpersonal needs related to suicidal ideation. This study aims to analyze the psychometrics properties of a Spanish adaptation of INQ-12 in fibromyalgia patients. Exploratory factor analysis (n = 180) and confirmatory factor analysis (n = 179) were performed in two randomly selected subsamples. The first analysis leads to the elimination of two items, whereas the second one confirmed the fit of the proposed two-factor structure. The reliability estimated using the Cronbach´s alpha coefficient and the Spearman-Brown coefficient was adequate. To obtain further validity evidence based on the relationship with other variables three variables were used. Moreover, a control group (n = 99) was used to contrast the means of INQ scores as evidence of validity based on differential scores. These findings support the usefulness of the Spanish version of the INQ-10 for assessing the degree of frustration of these interpersonal needs in patients with fibromyalgia

The Probiotic VSL#3 Does Not Seem to Be Efficacious for the Treatment of Gastrointestinal Symptomatology of Patients with Fibromyalgia: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Background: Gastrointestinal symptomatology is frequent among patients with fibromyalgia, which increases disease burden and lacks specific treatment, either pharmacological or nonpharmacological. We aimed to evaluate the efficacy and tolerability of a multi-strain probiotic, VSL#3®, for the treatment of fibromyalgia-associated gastrointestinal manifestations. Methods: This randomized, placebo-controlled trial included 12 weeks of probiotic or placebo treatment followed by 12 weeks of follow up. The primary outcome variable was the mean change from the baseline to the endpoint in the composite severity score of the three main gastrointestinal symptoms reported by patients with fibromyalgia (abdominal pain, abdominal bloating and meteorism). Secondary outcome variables were the severity of additional gastrointestinal symptoms, fibromyalgia severity, depression, sleep disturbance, health-related quality of life and patients’ overall impression of improvement. Results: No differences were found between VSL#3® (n = 54) and the placebo (n = 56) in the primary outcome (estimated treatment difference: 1.1; 95% confidence interval [CI]: −2.1, 4.2; p = 0.501), or in any of the secondary outcomes. However, responders to VSL#3 were more likely to maintain any improvement during the follow-up period compared to responders in the placebo arm. Overall, VSL#3 tolerability was good. Conclusion: Our data could not demonstrate any beneficial effects of VSL#3® either on the composite score of severity of abdominal pain, bloating and meteorism or in any of the secondary outcome variables. More research is needed to elucidate specific factors that may predict a favourable response to treatment in patients with fibromyalgia.Actial Farmaceutica Srl (Rome, Italy)Ferring SAU (Madrid, Spain)Neither Actial Farmaceutica Srl nor Ferring SAUActial Farmaceutica Sr

Odiel River (SW Spain), a Singular Scenario Affected by Acid Mine Drainage (AMD): Graphical and Statistical Models to Assess Diatoms and Water Hydrogeochemistry Interactions

The Odiel River (SW Spain) is one of the most cited rivers in the scientific literature due to its high pollution degree, generated by more than 80 sulphide mines’ (mostly unrestored) contamination in the Iberian Pyritic Belt (IPB), that have been exploited for more than 5000 years. Along the river and its tributaries, the physico-chemical parameters and diatoms, from 15 sampling points, were analyzed in the laboratory. Physico-chemical parameters, water chemical analysis, together with richness and Shannon–Wiener indexes were integrated in a matrix. An initial graphical treatment allowed the definition and proposal of a functioning system model, as well as the establishment of cause–effect relationships between pollution and its effects on biota. Then, the proposed model was statistically validated by factor analysis. For acidic pH waters, high values of Eh, TDS, sulphate, ∑REE and ∑Ficklin were found, while diatomologic indicators took low values. Thus, factor analysis was a very effective tool for graphical treatment validation as well as for pollution–biota interaction models’ formulation, governed by two factors: AMD processes and water balance suffered by the studied river. As a novelty, the cause–effect relationships between high barium concentration and low diversity and richness were demonstrated in the IPB, for the first time: The authors are grateful to the Departments of Biology and Geosciences of the University of Aveiro, Portugal where diatom samples were identified. The authors are grateful to the Sustainable Mining Engineering Research Group, Department of Mining, Mechanic, Energetic and Construction Engineering at the Higher Technical School of Engineering, University of Huelva, Spain for paying for the water analyses. AT Luís is funded by national funds (OE), through FCT—Fundação para a Ciência e a Tecnologia, I.P., in the scope of the framework contract foreseen in the numbers 4, 5 and 6 of the article 23, of the Decree-Law 57/2016, of 29 August, changed by Law 57/2017, of 19 Jul

Psychometric properties of the Spanish version of the 12-item Interpersonal Needs Questionnaire in fibromyalgia syndrome patients

Según la teoría interpersonal del suicidio, la pertenencia frustrada y la carga percibida son elementos clave en el desarrollo de la ideación suicida. El Cuestionario de necesidades interpersonales (INQ) fue diseñado para evaluar el grado de frustración de estas dos necesidades interpersonales relacionadas con la ideación suicida. El objetivo de este estudio fue analizar las propiedades psicométricas de una adaptación al español del INQ - 12 en pacientes con fibromialgia. Un análisis factorial exploratorio (n = 180) y un análisis factorial confirmatorio (n= 179) fueron realizados en dos submuestras seleccionadas al azar. El primer análisis llevó a la eliminación de dos ítems, mientras que el segundo confirmó el ajuste de la estructura propuesta de dos factores. La fiabilidad estimada mediante el coeficiente alfa de Cronbach y el coeficiente Spearman - Brown fue adecuada. Para obtener evidencias de validez basadas en la relación con otras variables, se utilizaron tres variables relacionadas con el suicidio. Además, se utilizó un grupo control (n = 99) para contrastar los promedios de las puntuaciones INQ como evidencia de validez basada en puntajes diferenciales. Estos hallazgos respaldan la utilidad de la versión española del INQ - 10 para evaluar el grado de frustración de estas necesidades interpersonales en pacientes con fibromialgia

Psychometric properties of the Spanish version of the 12-item Interpersonal Needs Questionnaire in fibromyalgia syndrome patients

Según la teoría interpersonal del suicidio, la pertenencia frustrada y la carga percibida son elementos clave en el desarrollo de la ideación suicida. El Cuestionario de necesidades interpersonales (INQ) fue diseñado para evaluar el grado de frustración de estas dos necesidades interpersonales relacionadas con la ideación suicida. El objetivo de este estudio fue analizar las propiedades psicométricas de una adaptación al español del INQ - 12 en pacientes con fibromialgia. Un análisis factorial exploratorio (n = 180) y un análisis factorial confirmatorio (n= 179) fueron realizados en dos submuestras seleccionadas al azar. El primer análisis llevó a la eliminación de dos ítems, mientras que el segundo confirmó el ajuste de la estructura propuesta de dos factores. La fiabilidad estimada mediante el coeficiente alfa de Cronbach y el coeficiente Spearman - Brown fue adecuada. Para obtener evidencias de validez basadas en la relación con otras variables, se utilizaron tres variables relacionadas con el suicidio. Además, se utilizó un grupo control (n = 99) para contrastar los promedios de las puntuaciones INQ como evidencia de validez basada en puntajes diferenciales. Estos hallazgos respaldan la utilidad de la versión española del INQ - 10 para evaluar el grado de frustración de estas necesidades interpersonales en pacientes con fibromialgia

Empoderamiento del alumnado adulto y de las personas mayores para una ciudadanía activa

Esta obra reúne iniciativas y experiencias de sensibilización y formación del profesorado y del alumnado adulto y mayor hacia una educación en competencias que contribuya a desarrollar la práctica de una ciudadanía activa compartiendo el tiempo libre, los conocimientos y las experiencias en proyectos sociales que consoliden y mejoren el entramado social de la ciudad, de las personas que la habitan y de la atención a sus necesidades. Su origen fue el proyecto CiudAct cofinanciado por el Programa Erasmus+ de la Unión Europea y en su desarrollo ha intervenido un equipo interinstitucional liderado por el Aula de Mayores+55 de la Universidad de Málaga y participado por el Centro de Profesorado «José Rodríguez Galán» de Antequera, la Asociación Cívica para la Prevención (ACP), la Asociación de Igualdad de Género Universitario (AIGU), y el Ayuntamiento de Faraján (Málaga). Con ellos, y con otras tantas instituciones y sus respectivos consorcios locales en toda Europa, se participa en la red supranacional Ciudades en Crecimiento.Programa Erasmus+ de la Unión Europea (referencia de proyecto 2015-1-ES01-KA104-014944