47 research outputs found
Constraints from Inflation on Scalar-Tensor Gravity Theories
We show how observations of the perturbation spectra produced during
inflation may be used to constrain the parameters of general scalar-tensor
theories of gravity, which include both an inflaton and dilaton field. An
interesting feature of these models is the possibility that the curvature
perturbations on super-horizon scales may not be constant due to non-adiabatic
perturbations of the two fields. Within a given model, the tilt and relative
amplitude of the scalar and tensor perturbation spectra gives constraints on
the parameters of the gravity theory, which may be comparable with those from
primordial nucleosynthesis and post-Newtonian experiments.Comment: LaTeX (with RevTex) 19 pages, 8 uuencoded figures appended, also
available on WWW via http://star.maps.susx.ac.uk/index.htm
Numerical study of pattern formation following a convective instability in non-Boussinesq fluids
We present a numerical study of a model of pattern formation following a
convective instability in a non-Boussinesq fluid. It is shown that many of the
features observed in convection experiments conducted on gas can be
reproduced by using a generalized two-dimensional Swift-Hohenberg equation. The
formation of hexagonal patterns, rolls and spirals is studied, as well as the
transitions and competition among them. We also study nucleation and growth of
hexagonal patterns and find that the front velocity in this two dimensional
model is consistent with the prediction of marginal stability theory for one
dimensional fronts.Comment: 9 pages, report FSU-SCRI-92-6
Scalar-Tensor Cosmological Models
We analyze the qualitative behaviors of scalar-tensor cosmologies with an
arbitrary monotonic function. In particular, we are interested
on scalar-tensor theories distinguishable at early epochs from General
Relativity (GR) but leading to predictions compatible with solar-system
experiments. After extending the method developed by Lorentz-Petzold and
Barrow, we establish the conditions required for convergence towards GR at
. Then, we obtain all the asymptotic analytical solutions
at early times which are possible in the framework of these theories. The
subsequent qualitative evolution, from these asymptotic solutions until their
later convergence towards GR, has been then analyzed by means of numerical
computations. From this analysis, we have been able to establish a
classification of the different qualitative behaviors of scalar-tensor
cosmological models with an arbitrary monotonic function.Comment: uuencoded compressed postscript file containing 41 pages, with 9
figures, accepted for publication in Physical Review
Identifying rail asset maintenance processes: a human-centric and sensemaking approach
Efficient asset maintenance is key for delivering services such as transport. Current rail maintenance processes have been mostly reactive with a recent shift towards exploring proactive modes. The introduction of new ubiquitous technologies and advanced data analytics facilitates the embedding of a âpredict-and-preventâ approach to managing assets. Successful, user-centred integration of such technology is still, however, a sparsely understood area. This study reports results from a set of interviews, based on Critical Decision Method, with rail asset maintenance and management experts regarding current procedural aspects of asset management and maintenance. We analyse and present the results from a human-centric sensemaking timeline perspective. We found that within a complex sociotechnical environment such as rail transport, asset maintenance processes apply not just at local levels, but also to broader, strategic levels that involve different stakeholders and necessitate different levels of expertise. This is a particularly interesting aspect within maintenance that has not been discussed as of yet within a process-based and timeline-based models of asset maintenance. We argue that it is important to consider asset maintenance activities within both micro (local) and macro (broader) levels to ensure reliability and stability in transport services. We also propose that the traditionally distinct notions of individual, collaborative and artefact-based sensemaking are in fact all in evidence in this sensemaking context, and argue that a more holistic view of sensemaking is therefore appropriate by placing these results within an amended Recogntion Primed Decsion making model
Clinical standards for the diagnosis and management of asthma in low- and middle-income countries
BACKGROUND:
The aim of these clinical standards is to aid the diagnosis and management of asthma in low-resource settings in low- and middle-income countries (LMICs).
METHODS:
A panel of 52 experts in the field of asthma in LMICs participated in a two-stage Delphi process to establish and reach a consensus on the clinical standards.
RESULTS:
Eighteen clinical standards were defined: Standard 1, Every individual with symptoms and signs compatible with asthma should undergo a clinical assessment; Standard 2, In individuals (>6 years) with a clinical assessment supportive of a diagnosis of asthma, a hand-held spirometry measurement should be used to confirm variable expiratory airflow limitation by demonstrating an acute response to a bronchodilator; Standard 3, Pre- and post-bronchodilator spirometry should be performed in individuals (>6 years) to support diagnosis before treatment is commenced if there is diagnostic uncertainty; Standard 4, Individuals with an acute exacerbation of asthma and clinical signs of hypoxaemia or increased work of breathing should be given supplementary oxygen to maintain saturation at 94â98%; Standard 5, Inhaled short-acting beta-2 agonists (SABAs) should be used as an emergency reliever in individuals with asthma via an appropriate spacer device for metered-dose inhalers; Standard 6, Short-course oral corticosteroids should be administered in appropriate doses to individuals having moderate to severe acute asthma exacerbations (minimum 3â5 days); Standard 7, Individuals having a severe asthma exacerbation should receive emergency care, including oxygen therapy, systemic corticosteroids, inhaled bronchodilators (e.g., salbutamol with or without ipratropium bromide) and a single dose of intravenous magnesium sulphate should be considered; Standard 8, All individuals with asthma should receive education about asthma and a personalised action plan; Standard 9, Inhaled medications (excluding dry-powder devices) should be administered via an appropriate spacer device in both adults and children. Children aged 0â3 years will require the spacer to be coupled to a face mask; Standard 10, Children aged <5 years with asthma should receive a SABA as-needed at step 1 and an inhaled corticosteroid (ICS) to cover periods of wheezing due to respiratory viral infections, and SABA as-needed and daily ICS from step 2 upwards; Standard 11, Children aged 6â11 years with asthma should receive an ICS taken whenever an inhaled SABA is used; Standard 12, All adolescents aged 12â18 years and adults with asthma should receive a combination inhaler (ICS and rapid onset of action long-acting beta-agonist [LABA] such as budesonide-formoterol), where available, to be used either as-needed (for mild asthma) or as both maintenance and reliever therapy, for moderate to severe asthma; Standard 13, Inhaled SABA alone for the management of patients aged >12 years is not recommended as it is associated with increased risk of morbidity and mortality. It should only be used where there is no access to ICS. The following standards (14â18) are for settings where there is no access to inhaled medicines. Standard 14, Patients without access to corticosteroids should be provided with a single short course of emergency oral prednisolone; Standard 15, Oral SABA for symptomatic relief should be used only if no inhaled SABA is available. Adjust to the individualâs lowest beneficial dose to minimise adverse effects; Standard 16, Oral leukotriene receptor antagonists (LTRA) can be used as a preventive medication and is preferable to the use of long-term oral systemic corticosteroids; Standard 17, In exceptional circumstances, when there is a high risk of mortality from exacerbations, low-dose oral prednisolone daily or on alternate days may be considered on a case-by-case basis; Standard 18. Oral theophylline should be restricted for use in situations where it is the only bronchodilator treatment option available.
CONCLUSION:
These first consensus-based clinical standards for asthma management in LMICs are intended to help clinicians provide the most effective care for people in resource-limited settings