A Virtual Reconstruction Methodology for Archaeological Heritage in East Asia – Practical Experience from the Re-relic Program in China

[EN] There is as much abundance of archaeological heritage in East Asia as there is diversity in the methodology for its reconstruction and representation. The Re-relic program in China recognizes the uniqueness of archaeological heritage in East Asia and has developed a tailored virtual reconstruction methodology that is both scientifically robust and popular for public interpretation. The theoretical consideration and field experience over the years shall contribute to the global understanding of the value and technique in virtual reconstruction, while testifying to the very principles of Seville Charter.[ES] El este de Asia se caracteriza tanto por su abundancia en patrimonio arqueológico como por su diversidad metodológica a la hora de llevar a cabo reconstrucciones y representaciones de dicho patrimonio. El programa Re-reliquia en China reconoce la singularidad del patrimonio arqueológico en el este de Asia y ha desarrollado una metodología adaptada para la reconstrucción virtual, científicamente sólida para la interpretación pública. El examen teórico y la experiencia de campo en los próximos años contribuirán a la comprensión global del valor y la técnica en la reconstrucción virtual, al prestar atención a los principios de la Carta de Sevilla.He, Y.; Gao, M.; Shang, J. (2013). A Virtual Reconstruction Methodology for Archaeological Heritage in East Asia – Practical Experience from the Re-relic Program in China. Virtual Archaeology Review. 4(9):93-99. https://doi.org/10.4995/var.2013.4253OJS939949GUO DAIHENG et al. (2002): Chinese Architecture, Yale University Press.HE, Yan (2011): "Re-relic/Yuanminguan: An Effective Practice in Virtual Restoration and Visual Representaion of Cultural Heritage", in CIPA symposium proceedings 2011.LIANG SSU CHENG, (1984): Chinese Architecture, A Pictorial History, MIT Press, Cambridge, Massachusetts.LOPEZ-MENCHERO, V.M. et al. (2011): "The Principles of the Seville Charter", in CIPA symposium proceedings 2011

Natural products as sources of new fungicides (I): synthesis and antifungal activity of Kakuol derivatives against phytopathogenic fungi

In order to establish an advanced structural-activity relationship (SAR) and to explore the feasibility of kakuol analogues with better anti-fungi activity, a series of 2-hydroxy-4,5-methylenedioxyaryl ketones were conveniently synthesized by the Friedel-Crafts acyl reaction, etherification reaction, reduction reaction and oximation reaction. Their structures characterized by 1H and 13C NMR and HRMS methods. Their in vitro antifungal activities were assayed. Most of the derivatives showed a remarkable in vitro activity, and some of them appeared significantly more effective than a commercial fungicide hymexazol as positive control. In particular compounds 2h and 2i, were found active with a IC50 value of 3.1 mg/ml and 2.9 mg/ml against Glomerella cingulate, which suggested that 2-hydroxy-4,5-methylenedioxyaryl ketones might be a promising candidates in the development of new antifungal compounds. Compounds 2e, 5 and 6 also exhibited high antifungal activities on a wide range of organisms, which might be considered as leading compounds in the development of new antifungal compounds.DOI: http://doi.dx.org/10.5564/mjc.v15i0.331 Mongolian Journal of Chemistry 15 (41), 2014, p94-10

Message Passing Based Block Sparse Signal Recovery for DOA Estimation Using Large Arrays

This work deals with directional of arrival (DOA) estimation with a large antenna array. We first develop a novel signal model with a sparse system transfer matrix using an inverse discrete Fourier transform (DFT) operation, which leads to the formulation of a structured block sparse signal recovery problem with a sparse sensing matrix. This enables the development of a low complexity message passing based Bayesian algorithm with a factor graph representation. Simulation results demonstrate the superior performance of the proposed method

人造血管在血液透析造瘘的应用及护理

Objective: To study the application of artificial blood vessels to build alternative standard arteriovenous fistula blood vessels for hemodialysis maintenance nursing. Methods: 17 cases of patients underwent artificial blood vessel transplantation, material for ptfe (PTEE), 30 cm in length, inner diameter 5mm, from 2012 to 2013 in Jinan military region general hospital. Artificial blood vessel transplantation is more operated on brachial vein, cephalic vein, median cubital vein and basilic vein. When the anastomosis among artificial blood vessels and brachial artery and vein anastomosis was established, the arterial end was on the inner side. When the anastomosis among brachial vein, median cubital vein and basilic vein was established, the arterial end was on the outside for the extension of vascular access. Results: 15 cases have hemodialysis after two months’ treatment, 1 case have artificial blood vessel fistula after swelling for 4 months, infection of thrombosis occurred one month after the operation in 1 case. Conclusion: Artificial blood vessel show good biocompatibility, high long-term patency rate, blood flow, and convenient puncture point. It builds the “lifeline” for the patients who are unable to establish a good vascular access. It is of great significance to improve the management of artificial blood vessel fistula for maintenance hemodialysis patients.目的  研究应用人造血管造瘘替代标准动静脉血管维持血液透析的护理。方法  本院自2012—2013年对17例血液透析患者进行人造血管移植术，材料为聚四氟乙烯（PTEE）材料，长度30cm，内径5mm。人造血管移植术多选择与肱动脉和头静脉或肘正中静脉、贵要静脉U型吻合。人造血管与肱动脉和头静脉吻合时，动脉端在内侧。但肱动脉与肘正中静脉、贵要静脉吻合时，为延长有效性血管通路，动脉端则在外侧。结果  15例术后2个月成熟顺利实施血液透析，1例持续肿胀4个月后开始应用，1例术后1个月出现感染血栓形成。结论  人造血管具有生物相容性好、长期通畅率高、血流量大、穿刺方便、穿刺部位充足等优点，为自身血管条件差、无法建立良好血管通路的透析患者提供了可靠的血管通路，为维持性血液透析患者建立了“生命线”。加强透析过程中的人造血管内瘘管理对于维持透析患者良好的血管通路具有重要意义

Joint trajectory inference for single-cell genomics using deep learning with a mixture prior

Trajectory inference methods are essential for analyzing the developmental paths of cells in single-cell sequencing datasets. It provides insights into cellular differentiation, transitions, and lineage hierarchies, helping unravel the dynamic processes underlying development and disease progression. However, many existing tools lack a coherent statistical model and reliable uncertainty quantification, limiting their utility and robustness. In this paper, we introduce VITAE (Variational Inference for Trajectory by AutoEncoder), a statistical approach that integrates a latent hierarchical mixture model with variational autoencoders to infer trajectories. The statistical hierarchical model enhances the interpretability of our framework, while the posterior approximations generated by our variational autoencoder ensure computational efficiency and provide uncertainty quantification of cell projections along trajectories. Specifically, VITAE enables simultaneous trajectory inference and data integration, improving the accuracy of learning a joint trajectory structure in the presence of biological and technical heterogeneity across datasets. We show that VITAE outperforms other state-of-the-art trajectory inference methods on both real and synthetic data under various trajectory topologies. Furthermore, we apply VITAE to jointly analyze three distinct single-cell RNA sequencing datasets of the mouse neocortex, unveiling comprehensive developmental lineages of projection neurons. VITAE effectively reduces batch effects within and across datasets and uncovers finer structures that might be overlooked in individual datasets. Additionally, we showcase VITAE’s efficacy in integrative analyses of multiomic datasets with continuous cell population structures