70 research outputs found
Static secondary ion mass spectrometry (S-SIMS) for the characterization of surface components in mineral particulates
Co-localization of QTL for root traits under low phosphorus availability with candidate genes homologues to PSTOL1 in maize.
QTL mapping and identification of putative PSTOL homologs associated with phosphorus acquisition traits in maize seedlings.
Quality evaluation of compounded capsules
The aim of this study was to evaluate the quality of compounded capsules of different drugs for chronic diseases. It were assessed two samples, from two different pharmacies, for each of the following drugs: ranitidine 150 mg, methyldopa 250 mg, enalapril maleate 20 mg, fluoxetine hydrochloride 20 mg, propranolol hydrochloride 40 mg, and furosemide 40 mg. The assays of mean weight, content determination, content uniformity and dissolution were performed according to Brazilian Pharmacopoeia. All samples were approved in the assay of mean weight, and the samples M1 and Flu1 had failed in the assay of content determination. In the test of uniformity of dosage units the samples M1, Flu1, E1, E2 and Flu2 had failed. Only the samples M2, P1, P2, F1 and F2 were accepted in all pharmacopoeial tests, evidencing that the others did not achieve the minimum requirements to ensure safety, quality and efficacy of the drugs.Colegio de Farmacéuticos de la Provincia de Buenos Aire
Study of Cluster Anions Generated by Laser Ablation of Titanium Oxides: A High Resolution Approach Based on Fourier Transform Ion Cyclotron Resonance Mass Spectrometry
Metabolite Profiles of Sugarcane Culm Reveal the Relationship Among Metabolism and Axillary Bud Outgrowth in Genetically Related Sugarcane Commercial Cultivars
Metabolic composition is known to exert influence on several important agronomic traits, and metabolomics, which represents the chemical composition in a cell, has long been recognized as a powerful tool for bridging phenotype–genotype interactions. In this work, sixteen truly representative sugarcane Brazilian varieties were selected to explore the metabolic networks in buds and culms, the tissues involved in the vegetative propagation of this species. Due to the fact that bud sprouting is a key trait determining crop establishment in the field, the sprouting potential among the genotypes was evaluated. The use of partial least square discriminant analysis indicated only mild differences on bud outgrowth potential under controlled environmental conditions. However, primary metabolite profiling provided information on the variability of metabolic features even under a narrow genetic background, typical for modern sugarcane cultivars. Metabolite–metabolite correlations within and between tissues revealed more complex patterns for culms in relation to buds, and enabled the recognition of key metabolites (e.g., sucrose, putrescine, glutamate, serine, and myo-inositol) affecting sprouting ability. Finally, those results were associated with the genetic background of each cultivar, showing that metabolites can be potentially used as indicators for the genetic background
Sugarcane (Saccharum X officinarum): A Reference Study for the Regulation of Genetically Modified Cultivars in Brazil
Global interest in sugarcane has increased significantly in recent years due to its economic impact on sustainable energy production. Sugarcane breeding and better agronomic practices have contributed to a huge increase in sugarcane yield in the last 30Â years. Additional increases in sugarcane yield are expected to result from the use of biotechnology tools in the near future. Genetically modified (GM) sugarcane that incorporates genes to increase resistance to biotic and abiotic stresses could play a major role in achieving this goal. However, to bring GM sugarcane to the market, it is necessary to follow a regulatory process that will evaluate the environmental and health impacts of this crop. The regulatory review process is usually accomplished through a comparison of the biology and composition of the GM cultivar and a non-GM counterpart. This review intends to provide information on non-GM sugarcane biology, genetics, breeding, agronomic management, processing, products and byproducts, as well as the current technologies used to develop GM sugarcane, with the aim of assisting regulators in the decision-making process regarding the commercial release of GM sugarcane cultivars
Laser ablation mass spectrometry of inorganic transition metal compounds. Additional knowledge for the understanding of ion formation
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