Modeling specific action potentials in the human atria based on a minimal reaction-diffusion model

We present an effective method to model empirical action potentials of specific patients in the human atria based on the minimal model of Bueno-Orovio, Cherry and Fenton adapted to atrial electrophysiology. In this model, three ionic are currents introduced, where each of it is governed by a characteristic time scale. By applying a nonlinear optimization procedure, a best combination of the respective time scales is determined, which allows one to reproduce specific action potentials with a given amplitude, width and shape. Possible applications for supporting clinical diagnosis are pointed out.Comment: 16 pages, 8 figure

The Ambient Horn: Designing a novel audio-based learning experience

The Ambient Horn is a novel handheld device designed to support children learning about habitat distributions and interdependencies in an outdoor woodland environment. The horn was designed to emit non-speech audio sounds representing ecological processes. Both symbolic and arbitrary mappings were used to represent the processes. The sounds are triggered in response to the children’s location in certain parts of the woodland. A main objective was to provoke children into interpreting and reflecting upon the significance of the sounds in the context in which they occur. Our study of the horn being used showed the sounds to be provocative, generating much discussion about what they signified in relation to what the children saw in the woodland. In addition, the children appropriated the horn in creative ways, trying to ‘scoop’ up new sounds as they walked in different parts of the woodland

Infrared studies of dust grains in infrared reflection nebulae

IR reflection nebulae, regions of dust which are illuminated by nearby embedded sources, were observed in several regions of ongoing star formation. Near IR observation and theoretical modelling of the scattered light form IR reflection nebulae can provide information about the dust grain properties in star forming regions. IR reflection nebulae were modelled as plane parallel slabs assuming isotropically scattering grains. For the grain scattering properties, graphite and silicate grains were used with a power law grain size distribution. Among the free parameters of the model are the stellar luminosity and effective temperature, the optical depth of the nebula, and the extinction by foreground material. The typical results from this model are presented and discussed

Development and validation of risk profiles of West African rural communities facing multiple natural hazards

West Africa has been described as a hotspot of climate change. The reliance on rain-fed agriculture by over 65% of the population means that vulnerability to climatic hazards such as droughts, rainstorms and floods will continue. Yet, the vulnerability and risk levels faced by different rural social-ecological systems (SES) affected by multiple hazards are poorly understood. To fill this gap, this study quantifies risk and vulnerability of rural communities to drought and floods. Risk is assessed using an indicator-based approach. A stepwise methodology is followed that combines participatory approaches with statistical, remote sensing and Geographic Information System techniques to develop community level vulnerability indices in three watersheds (Dano, Burkina Faso; Dassari, Benin; Vea, Ghana). The results show varying levels of risk profiles across the three watersheds. Statistically significant high levels of mean risk in the Dano area of Burkina Faso are found whilst communities in the Dassari area of Benin show low mean risk. The high risk in the Dano area results from, among other factors, underlying high exposure to droughts and rainstorms, longer dry season duration, low caloric intake per capita, and poor local institutions. The study introduces the concept of community impact score (CIS) to validate the indicator-based risk and vulnerability modelling. The CIS measures the cumulative impact of the occurrence of multiple hazards over five years. 65.3% of the variance in observed impact of hazards/CIS was explained by the risk models and communities with high simulated disaster risk generally follow areas with high observed disaster impacts. Results from this study will help disaster managers to better understand disaster risk and develop appropriate, inclusive and well integrated mitigation and adaptation plans at the local level. It fulfills the increasing need to balance global/regional assessments with community level assessments where major decisions against risk are actually taken and implemented

Corporate Boards and Ownership Structure as Antecedents of Corporate Governance Disclosure in Saudi Arabian Publicly Listed Corporations

We investigate whether and to what extent publicly listed corporations voluntarily comply with and disclose recommended good corporate governance (CG) practices, and distinctively examine whether the observed cross-sectional differences in such CG disclosures can be explained by ownership and board mechanisms with specific focus on Saudi Arabia. Our results suggest that corporations with larger boards, a big-four auditor, higher government ownership, a CG committee and higher institutional ownership disclose considerably more than those that are not. By contrast, we find that an increase in block ownership significantly reduces CG disclosure. Our results are generally robust to a number of econometric models that control for different types of disclosure indices, firm-specific characteristics and firm-level fixed-effects. Our results have important implications for policy-makers, practitioners and regulatory authorities, especially those in developing countries across the globe

Cosmological axion bounds

We discuss current cosmological constraints on axions, as well as future sensitivities. Bounds on axion hot dark matter are discussed first, and subsequently we discuss both current and future sensitivity to models in which axions play the role as cold dark matter, but where the Peccei-Quinn symmetry is not restored during reheating.Comment: 4 pages, 2 figures, To appear in the proceedings of 5th Patras Workshop on Axions, WIMPs and WISPs, Durham 13-17 July 200

Cosmology seeking friendship with sterile neutrinos

Precision cosmology and big-bang nucleosynthesis mildly favor extra radiation in the universe beyond photons and ordinary neutrinos, lending support to the existence of low-mass sterile neutrinos. We use the WMAP 7-year data, small-scale CMB observations from ACBAR, BICEP and QuAD, the SDSS 7th data release, and measurement of the Hubble parameter from HST observations to derive credible regions for the assumed common mass scale m_s and effective number N_s of thermally excited sterile neutrino states. Our results are compatible with the existence of one or perhaps two sterile neutrinos, as suggested by LSND and MiniBooNE, if m_s is in the sub-eV range.Comment: 4 pages, 1 figure, matches version published in PR

Magneto-optical study of electron occupation and hole wave functions in stacked self-assembled InP quantum dots

We have studied the magnetophotoluminescence of doubly stacked layers of self-assembled InP quantum dots in a GaInP matrix. 4.0±0.1 monolayers of InP were deposited in the lower layer of each sample, whereas in the upper layer 3.9, 3.4, and 3.0 monolayers were used. Low-temperature photoluminescence measurements in zero magnetic field are used to show that, in each case, only one layer of dots is occupied by an electron, and imply that when the amount of InP in both layers is the same, the dots in the upper layer are larger. High-field photoluminescence data reveal that the position and extent of the hole wave function are strongly dependent on the amount of InP in the stack. ©2001 American Institute of Physics