A Report of Nausea and Vomiting with Discontinuation of Chronic Use of Salvia divinorum

Introduction. This is the first reported case of gastrointestinal symptoms associated with withdrawal after chronic use of this substance. Case Presentation. A 51-year-old Caucasian woman was referred to a hospital with a 3-day history of nausea, vomiting, diarrhea, and abdominal discomfort. She reported no sick family members or contact with anyone who was ill. She did report smoking 3–5 cigarettes of the herb “Salvia” consistently for 3-4 months and quit approximately 48 hours before symptoms appeared. Her use of the herb had been consistent; she smoked several cigarettes each day. Laboratory results were essentially normal including the white blood cell count. She received symptomatic treatment and was released after one day. Discussion. Salvinorin A, a kappa-opioid receptor agonist, is the major active ingredient of S. divinorum. The unique opioid properties of this herb may explain its ability to cause changes in intestinal transit time. Conclusion. A 51-year-old woman possibly developed gastrointestinal manifestations suggestive of withdrawal from Salvia divinorum after smoking the substance consistently for 3 to 4 months. The widespread use of this herb will make the potential for withdrawal syndromes more commonplace

Thermal Analysis of a Metallic Wing Glove for a Mach-8 Boundary-Layer Experiment

A metallic 'glove' structure has been built and attached to the wing of the Pegasus(trademark) space booster. An experiment on the upper surface of the glove has been designed to help validate boundary-layer stability codes in a free-flight environment. Three-dimensional thermal analyses have been performed to ensure that the glove structure design would be within allowable temperature limits in the experiment test section of the upper skin of the glove. Temperature results obtained from the design-case analysis show a peak temperature at the leading edge of 490 F. For the upper surface of the glove, approximately 3 in. back from the leading edge, temperature calculations indicate transition occurs at approximately 45 sec into the flight profile. A worst-case heating analysis has also been performed to ensure that the glove structure would not have any detrimental effects on the primary objective of the Pegasus a launch. A peak temperature of 805 F has been calculated on the leading edge of the glove structure. The temperatures predicted from the design case are well within the temperature limits of the glove structure, and the worst-case heating analysis temperature results are acceptable for the mission objectives

Developing a Culturally Proficient Intervention for Young African American Men in Drug Court: Examining Feasibility and Estimating an Effect Size for Habilitation Empowerment Accountability Therapy (HEAT)

African American males between 18 and 29 years of age are substantially less likely than many other participants to graduate successfully from drug court. Unsuccessful termination from drug court can have serious repercussions for these young men, including possible incarceration and negative collateral consequences associated with having a criminal record. This article reports preliminary results from two pilot studies that examined the feasibility of implementing a culturally proficient intervention for young African American men in drug court, and estimated an effect size for the intervention in improving treatment retention and reducing termination rates. Results confirmed that participants with serious criminal and substance use histories were willing and able to complete the lengthy 9-month curriculum, were satisfied with the intervention, and graduated from drug court at substantially higher rates than are commonly observed in this at-risk population. A sufficient basis has been established to justify the effort and expense of examining this intervention — Habilitation Empowerment Accountability Therapy (HEAT) — in fully powered randomized controlled trials

Numerical simulations of shocks encountering clumpy regions

We present numerical simulations of the adiabatic interaction of a shock with a clumpy region containing many individual clouds. Our work incorporates a sub-grid turbulence model which for the first time makes this investigation feasible. We vary the Mach number of the shock, the density contrast of the clouds, and the ratio of total cloud mass to inter-cloud mass within the clumpy region. Cloud material becomes incorporated into the flow. This "mass-loading" reduces the Mach number of the shock, and leads to the formation of a dense shell. In cases in which the mass-loading is sufficient the flow slows enough that the shock degenerates into a wave. The interaction evolves through up to four stages: initially the shock decelerates; then its speed is nearly constant; next the shock accelerates as it leaves the clumpy region; finally it moves at a constant speed close to its initial speed. Turbulence is generated in the post-shock flow as the shock sweeps through the clumpy region. Clouds exposed to turbulence can be destroyed more rapidly than a similar cloud in an "isolated" environment. The lifetime of a downstream cloud decreases with increasing cloud-to-intercloud mass ratio. We briefly discuss the significance of these results for starburst superwinds and galaxy evolution.Comment: 17 pages, 19 figures, accepted for publication in MNRA

On faint companions in the close environment of star-forming dwarf galaxies. Possible external star formation triggers ?

We have searched for companion galaxies in the close environment of 98 star-forming dwarf galaxies (SFDGs) from field and low density environments, using the NASA Extragalactic Database. Most of the companions are dwarf galaxies which due to observational selection effects were previously disregarded in environmental studies of SFDGs. A subsample at low redshift, cz<2000 km/s, was chosen to partially eliminate the observational bias against distant dwarf companions. We find companion candidates for approximately 30% of the objects within a projected linear separation s_p<100 kpc and a redshift difference (Delta cz)<500 km/s. The limited completeness of the available data sets, together with the non-negligible frequency of HI clouds in the vicinity of SFDGs indicated by recent radio surveys, suggest that a considerably larger fraction of these galaxies may be accompanied by low-mass systems. This casts doubt on the hypothesis that the majority of them can be considered truly isolated. The velocity differences between companion candidates and sample SFDGs amount typically to (Delta cz)<250 km/s, and show a rising distribution towards lower (Delta cz). This is similarly found for dwarf satellites of spiral galaxies, suggesting a physical association between the companion candidates and the sample SFDGs. SFDGs with a close companion do not show significant differences in their Hbeta equivalent widths and B-V colours as compared to isolated ones. However, the available data do not allow us to rule out that interactions with close dwarf companions can influence the star formation activity in SFDGs.Comment: 9 pages, 5 figures, to appear in A&A; also available at http://www.uni-sw.gwdg.de/~knoeske/PUB_LIST/sfdg_comps.ps.g

New southern blue compact dwarf galaxies in the 2dF Galaxy Redshift Survey

Aiming to find new extremely metal-deficient star-forming galaxies we extracted from the Two-Degree Field Galaxy Redshift Survey (2dFGRS) 100K Data Release 14 emission-line galaxies with relatively strong [OIII] 4363 emission. Spectroscopic and photometric studies of this sample and, in addition, of 7 Tololo and 2 UM galaxies were performed on the basis of observations with the ESO 3.6m telescope. All sample galaxies qualify with respect to their photometric and spectroscopic properties as blue compact dwarf (BCD) galaxies. Additionally, they show a good overlap with a comparison sample of 100 well-studied emission-line galaxies on the 12+log(O/H) vs. log(Ne/O), log(Ar/O) and log(Fe/O) planes. From the analysis of the 2dFGRS subsample we report the discovery of two new extremely metal-deficient BCDs with an oxygen abundance 12+log(O/H) < 7.6 and of another seven galaxies with 12+log(O/H) < 7.8. Furthermore, we confirm previous oxygen abundance determinations for the BCDs Tol 1304-353, Tol 2146-391, UM 559 and UM 570 to be 12+log(O/H) < 7.8.Comment: 26 pages, 65 figures, 5 tables, uses psfig.sty, Accepted for publication in Astronomy and Astrophysics. The paper with high-resolution figures can be downloaded at http://www.uni-sw.gwdg.de/~papade/Publications/Papaderos2006_2dF.pd