6,195 research outputs found
Circumbinary disk evolution
We study the evolution of circumbinary disks surrounding classical T Tau stars. High resolution numerical simulations are employed to model a system consisting of a central eccentric binary star within an accretion disk. The disk is assumed to be infinitesimally thin, however a detailed energy balance including viscous heating and radiative cooling is applied. A novel numerical approach using a parallelized Dual-Grid technique on two different coordinate systems has been implemented. Physical parameters of the setup are chosen to model the close systems of DQ Tau and AK Sco, as well as the wider systems of GG Tau and UY Aur. Our main findings are for the tight binaries a substantial flow of material through the disk gap which is accreted onto the central stars in a phase dependent process. We are able to constrain the parameters of the systems by matching both accretion rates and derived spectral energy distributions to observational data where available
Electronic structure of intermetallics based on a rare earth element and a transition or noble metal
The results of ab initio study of resonant surface states genesis in the vicinity of Ξ point for GdRh[2]Si[2] are presented in this work. Our electronic band structure calculations have shown that the resonant surface states are already formed in three atomic layer slab Si-Rh-Si. The states localization within three layer slab causes its resonant nature and presence of these states on Si- and Gd- termination surfaces
Π Π°Π·ΡΠ°Π±ΠΎΡΠΊΠ° ΡΠΏΠΎΡΠΎΠ±ΠΎΠ², Π°Π»Π³ΠΎΡΠΈΡΠΌΠΎΠ² ΠΈ ΠΏΡΠΎΠ³ΡΠ°ΠΌΠΌ ΠΎΠ±Π½Π°ΡΡΠΆΠ΅Π½ΠΈΡ ΠΈ ΠΈΡΠΏΡΠ°Π²Π»Π΅Π½ΠΈΡ ΠΏΠ°ΠΊΠ΅ΡΠ½ΡΡ ΠΈΠ»ΠΈ Π½Π΅Π·Π°Π²ΠΈΡΠΈΠΌΡΡ ΠΎΡΠΈΠ±ΠΎΠΊ ΠΏΡΠΈ ΠΏΠ΅ΡΠ΅Π΄Π°ΡΠ΅ Π΄Π°Π½Π½ΡΡ ΠΏΠΎ ΠΊΠ°Π½Π°Π»Π°ΠΌ ΡΠ²ΡΠ·ΠΈ
ΠΠ°ΡΡΠΎΡΡΠ°Ρ Π½Π°ΡΡΠ½ΠΎ-ΠΊΠ²Π°Π»ΠΈΡΠΈΠΊΠ°ΡΠΈΠΎΠ½Π½Π°Ρ ΡΠ°Π±ΠΎΡΠ° ΠΏΠΎΡΠ²ΡΡΠ΅Π½Π° ΡΠ°Π·ΡΠ°Π±ΠΎΡΠΊΠ΅ ΡΠΏΠΎΡΠΎΠ±ΠΎΠ², Π°Π»Π³ΠΎΡΠΈΡΠΌΠΎΠ² ΠΈ ΠΏΡΠΎΠ³ΡΠ°ΠΌΠΌ ΠΎΠ±Π½Π°ΡΡΠΆΠ΅Π½ΠΈΡ ΠΈ ΠΈΡΠΏΡΠ°Π²Π»Π΅Π½ΠΈΡ ΠΎΡΠΈΠ±ΠΎΠΊ ΠΏΡΠΈ ΠΏΠ΅ΡΠ΅Π΄Π°ΡΠ΅ Π΄Π°Π½Π½ΡΡ
ΠΏΠΎ ΠΊΠ°Π½Π°Π»Π°ΠΌ ΡΠ²ΡΠ·ΠΈ Π΄Π»Ρ ΠΎΠ±Π΅ΡΠΏΠ΅ΡΠ΅Π½ΠΈΡ ΡΠ΅Π»ΠΎΡΡΠ½ΠΎΡΡΠΈ ΠΈ Π½Π°Π΄ΡΠΆΠ½ΠΎΡΡΠΈ ΠΏΠ΅ΡΠ΅Π΄Π°Π²Π°Π΅ΠΌΡΡ
ΠΊΠΎΠΌΠ°Π½Π΄ ΠΈ Π΄Π°Π½Π½ΡΡ
ΠΌΠ΅ΠΆΠ΄Ρ ΡΡΡΡΠΎΠΉΡΡΠ²Π°ΠΌΠΈ Π²ΡΡΠΈΡΠ»ΠΈΡΠ΅Π»ΡΠ½ΠΎ ΡΠ΅Ρ
Π½ΠΈΠΊΠΈ, Π° ΡΠ°ΠΊΠΆΠ΅ ΠΏΡΠΈ ΡΡΠΈΡΡΠ²Π°Π½ΠΈΠΈ Π΄Π°Π½Π½ΡΡ
ΠΈΠ· Π·Π°ΠΏΠΎΠΌΠΈΠ½Π°ΡΡΠΈΡ
ΡΡΡΡΠΎΠΉΡΡΠ².The present scientific and qualification work is devoted to the development of methods, algorithms and programs for detecting and correcting errors in the transmission of data over communication channels to ensure the integrity and reliability of the transmitted commands and data between computing devices, as well as when reading data from memory devices
Temozolomide induces apoptosis and senescence in glioma cells cultured as multicellular spheroids
Temozolomide is an alkylating cytostatic drug that finds increasing application in the treatment of melanoma, anaplastic astrocytoma and glioblastoma multiforme. The compound is a prodrug that decomposes spontaneously, independent of an enzymatic activation step. DNA methylation induces futile mismatch repair cycles and depletion of the DNA repair enzyme O6-methylguanine-DNA methyltransferase should then initiate programmed cell death. We show drug-dependent inhibition of tumour growth in a three-dimensional cell culture model of the glioma cell lines U87MG and GaMG. Migrational behaviour of the glioblastoma cells remained unaltered. However, coincubation of tumour spheroids with primary brain aggregates showed reduced tumour cell invasion into brain tissue in the presence of temozolomide. This was not achieved by slowing cellular migration, as temozolomide-treated cells displayed no reduced motility. By transferase-mediated dUTP nick-end labelling (TUNEL) of apoptotic nuclei, we found that the drug was able to induce apoptosis throughout the tumour cell spheroids. Apoptosis was highest in the core region of the spheroids. Repetitive application of sublethal doses of temozolomide to multicellular spheroids resulted in the development of drug resistance in GaMG cells. We suggest that temozolomide is a strong initiator of apoptosis in glioblastoma tumour cells in a spheroid cell culture system, when cells are already in a stressful environment
Huygens' Principle for the Klein-Gordon equation in the de Sitter spacetime
In this article we prove that the Klein-Gordon equation in the de Sitter
spacetime obeys the Huygens' principle only if the physical mass of the
scalar field and the dimension of the spatial variable are tied by
the equation . Moreover, we define the incomplete Huygens'
principle, which is the Huygens' principle restricted to the vanishing second
initial datum, and then reveal that the massless scalar field in the de Sitter
spacetime obeys the incomplete Huygens' principle and does not obey the
Huygens' principle, for the dimensions , only. Thus, in the de Sitter
spacetime the existence of two different scalar fields (in fact, with m=0 and
), which obey incomplete Huygens' principle, is equivalent to
the condition (in fact, the spatial dimension of the physical world). For
these two values of the mass are the endpoints of the so-called in
quantum field theory the Higuchi bound. The value of the
physical mass allows us also to obtain complete asymptotic expansion of the
solution for the large time. Keywords: Huygens' Principle; Klein-Gordon
Equation; de Sitter spacetime; Higuchi Boun
ΠΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠΈ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΡΠ²Π°ΡΠ½ΠΎΠ³ΠΎ ΡΠ²Π° Π² ΠΈΠ·Π΄Π΅Π»ΠΈΡΡ ΠΈΠ· ΡΠΈΡΠ°Π½ΠΎΠ²ΠΎΠ³ΠΎ ΡΠΏΠ»Π°Π²Π° Ti-6Al-4V, ΠΏΠΎΠ»ΡΡΠ΅Π½Π½ΡΡ Π°Π΄Π΄ΠΈΡΠΈΠ²Π½ΡΠΌΠΈ ΠΌΠ΅ΡΠΎΠ΄Π°ΠΌΠΈ
Π Π΄Π°Π½Π½ΠΎΠΉ ΡΠ°Π±ΠΎΡΠ΅ ΠΏΡΠΎΠ²ΠΎΠ΄ΠΈΠ»ΡΡ ΡΡΠ°Π²Π½ΠΈΡΠ΅Π»ΡΠ½ΡΡ
Π°Π½Π°Π»ΠΈΠ· ΠΌΠΈΠΊΡΠΎΡΡΡΡΠΊΡΡΡΡ ΠΈ ΠΌΠΈΠΊΡΠΎΡΠ²Π΅ΡΠ΄ΠΎΡΡΠΈ ΡΠ²Π°ΡΠ½ΡΡ
ΡΠΎΠ΅Π΄ΠΈΠ½Π΅Π½ΠΈΠΉ, ΠΏΠΎΠ»ΡΡΠ΅Π½Π½ΡΡ
ΠΌΠ΅ΡΠΎΠ΄ΠΎΠΌ ΡΠ»Π΅ΠΊΡΡΠΎΠ½Π½ΠΎΠ»ΡΡΠ΅Π²ΠΎΠΉ ΡΠ²Π°ΡΠΊΠΈ (ΠΠΠ‘). Π ΠΊΠ°ΡΠ΅ΡΡΠ²Π΅ ΠΎΠ±ΡΠ°Π·ΡΠΎΠ² ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π»ΠΈΡΡ ΠΏΠ»Π°ΡΡΠΈΠ½Ρ, ΠΏΠΎΠ»ΡΡΠ΅Π½Π½ΡΠ΅ ΠΏΡΠΎΠΊΠ°ΡΠΊΠΎΠΉ ΠΈ Π°Π΄Π΄ΠΈΡΠΈΠ²Π½ΡΠΌ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠΌ EBF{3} (electronbeam freeform fabrication - ΡΠ»Π΅ΠΊΡΡΠΎΠ½Π½ΠΎ-Π»ΡΡΠ΅Π²ΠΎΠ΅ ΠΈΠ·Π³ΠΎΡΠΎΠ²Π»Π΅Π½ΠΈΠ΅ ΡΠ²ΠΎΠ±ΠΎΠ΄Π½ΠΎΠΉ ΡΠΎΡΠΌΡ). ΠΡΡΠ²Π»Π΅Π½ΠΎ Π°Π½Π°Π»ΠΎΠ³ΠΈΡΠ½ΠΎΠ΅ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ ΡΡΠ΅Ρ
ΡΠ²Π°ΡΠΎΡΠ½ΡΡ
Π·ΠΎΠ½ ΠΏΠΎΡΠ»Π΅ ΠΠΠ‘ Π² 3D-Π½Π°ΠΏΠ΅ΡΠ°ΡΠ°Π½Π½ΡΡ
ΠΎΠ±ΡΠ°Π·ΡΠ°Ρ
. ΠΠΎΠΊΠ°Π·Π°Π½ΠΎ Π²Π»ΠΈΡΠ½ΠΈΠ΅ ΠΈΡΡ
ΠΎΠ΄Π½ΠΎΠΉ ΡΡΡΡΠΊΡΡΡΡ Π½Π° ΠΏΡΠΎΡΠ΅ΡΡ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΡΠ²Π°ΡΠ½ΠΎΠ³ΠΎ ΡΠΎΠ΅Π΄ΠΈΠ½Π΅Π½ΠΈΡ. ΠΠ· ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠΎΠ² Π΄ΡΡΠΎΠΌΠ΅ΡΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π°Π½Π°Π»ΠΈΠ·Π° ΡΠ»Π΅Π΄ΡΠ΅Ρ, ΡΡΠΎ Π·ΠΎΠ½Π° ΠΏΠ»Π°Π²Π»Π΅Π½ΠΈΡ (FZ) Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΠ·ΡΠ΅ΡΡΡ ΠΏΠΎΠ²ΡΡΠ΅Π½Π½ΠΎΠΉ ΠΌΠΈΠΊΡΠΎΡΠ²Π΅ΡΠ΄ΠΎΡΡΡΡ ΠΎΡΠ½ΠΎΡΠΈΡΠ΅Π»ΡΠ½ΠΎ ΠΎΡΠ½ΠΎΠ²Π½ΠΎΠ³ΠΎ ΠΌΠ°ΡΠ΅ΡΠΈΠ°Π»Π°. ΠΠ΄Π½Π°ΠΊΠΎ Π² ΡΠ»ΡΡΠ°Π΅ ΠΎΠ±ΡΠ°Π·ΡΠΎΠ², ΠΏΠΎΠ»ΡΡΠ΅Π½Π½ΡΡ
ΠΌΠ΅ΡΠΎΠ΄ΠΎΠΌ EBF{3}, Ρ
Π°ΡΠ°ΠΊΡΠ΅Ρ ΠΏΠΎΠ²ΡΡΠ΅Π½ΠΈΡ ΠΎΡΠ»ΠΈΡΠ°Π΅ΡΡΡ, ΡΡΠΎ ΡΠ²ΡΠ·Π°Π½ΠΎ Ρ ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΡΠΌΠΈ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΡΠ²Π°ΡΠ½ΠΎΠ³ΠΎ ΡΠ²Π°.Comparing analysis of the microstructure and microhardness has been investigated in electron-beam welded Ti-6Al-4V alloy parts obtained by rolling and additive manufacturing. Electron-beam welding produced three distinct zones (FZ - the fusion zone, HAZ - the heat affected zone, BM - the base metal) in the welded material. The influence of the BM on the structure of welded joint is shown. According to the results of microhardness testing, it follows that in the FZ the microhardness is higher than in the BM. However, for samples obtained by EBF{3}, the nature of the increase is different due to the features of the formed microstructure during welding
ΠΠΎΠ²ΡΡΠ΅Π½ΠΈΠ΅ ΡΠ½Π΅ΡΠ³Π΅ΡΠΈΡΠ΅ΡΠΊΠΈΡ Ρ Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΡΡΠΈΠΊ ΠΎΡΠ³Π°Π½ΠΎΠ²ΠΎΠ΄ΠΎΡΠ³ΠΎΠ»ΡΠ½ΡΡ ΡΠΎΠΏΠ»ΠΈΠ² Π·Π° ΡΡΠ΅Ρ Π΄ΠΎΠ±Π°Π²Π»Π΅Π½ΠΈΡ ΠΌΠ΅ΡΠ°Π»Π»ΠΈΡΠ΅ΡΠΊΠΈΡ ΡΠ°ΡΡΠΈΡ
Π Π½Π°ΡΡΠ½ΠΎ-ΠΊΠ²Π°Π»ΠΈΡΠΈΠΊΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΉ ΡΠ°Π±ΠΎΡΠ΅ ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½Ρ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΡ ΡΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ°Π»ΡΠ½ΡΡ
ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΉ ΠΏΡΠΎΡΠ΅ΡΡΠΎΠ², ΠΏΡΠΎΡΠ΅ΠΊΠ°ΡΡΠΈΡ
ΠΏΡΠΈ Π·Π°ΠΆΠΈΠ³Π°Π½ΠΈΠΈ ΠΎΡΠ³Π°Π½ΠΎΠ²ΠΎΠ΄ΠΎΡΠ³ΠΎΠ»ΡΠ½ΡΡ
ΡΠΎΠΏΠ»ΠΈΠ² Ρ Π΄ΠΎΠ±Π°Π²Π»Π΅Π½ΠΈΠ΅ΠΌ ΠΌΠ΅ΡΠ°Π»Π»ΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠ°ΡΡΠΈΡ.ΠΠΎ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠ°ΠΌ ΡΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ°Π»ΡΠ½ΡΡ
ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΉ ΡΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½Ρ ΠΎΡΠ»ΠΈΡΠΈΡ ΡΡΠ°Π΄ΠΈΠΉ Π·Π°ΠΆΠΈΠ³Π°Π½ΠΈΡ ΠΌΠ΅ΡΠ°Π»Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
ΡΠΎΡΡΠ°Π²ΠΎΠ² ΠΠ£Π’ ΠΈ ΠΠΠ£Π’ ΠΎΡ ΠΈΡΡ
ΠΎΠ΄Π½ΡΡ
. ΠΡΠ΄Π΅Π»Π΅Π½Ρ ΡΠ΅ΠΌΠΏΠ΅ΡΠ°ΡΡΡΠ½ΡΠ΅ Π΄ΠΈΠ°ΠΏΠ°Π·ΠΎΠ½Ρ Π·Π°ΠΆΠΈΠ³Π°Π½ΠΈΡ ΡΠΎΠΏΠ»ΠΈΠ² Ρ Π΄ΠΎΠ±Π°Π²Π»Π΅Π½ΠΈΠ΅ΠΌ ΡΠ°ΡΡΠΈΡ ΠΌΠ΅ΡΠ°Π»Π»Π°, ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½Ρ ΡΠ°Π·ΠΌΠ΅ΡΡ ΡΠ°ΡΡΠΈΡ ΠΌΠ΅ΡΠ°Π»Π»Π°, Π½Π°ΠΈΠ±ΠΎΠ»Π΅Π΅ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎ Π²Π»ΠΈΡΡΡΠΈΠ΅ Π½Π° ΡΠ½Π΅ΡΠ³Π΅ΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΡΡΠΈΠΊΠΈ ΡΠΎΠΏΠ»ΠΈΠ².The scientific qualification work show the results of experimental studies of the processes occurring during the ignition of organic coal-water slurry with the addition of metal particles. identified differences of the ignition stages of metallized compositions of CWS and OCWS from the initial. The temperature ranges of ignition of fuels with the addition of metal particles are identified, the sizes of metal particles that most effectively affect the energy characteristics of the fuel are determined
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