Electric Car Purchase Price as a Factor Determining Consumers’ Choice and their Views on Incentives in Europe

The deployment of zero-emission vehicles has the potential to drastically reduce air pollution and greenhouse gas emissions from road transport. The purpose of this study is to provide evidence on, and quantify the factors that influence, the European market for electric and fuel cell car technologies. The paper reports the results of a stated preference survey among 1,248 car owners in France, Germany, Italy, Poland, Spain and the United Kingdom. The variables that influence powertrain choice are quantified in a nested multinomial logit model. We find that the electric car purchase price continues to be a major deterrent to sales in the surveyed countries. The majority of the respondents considered government incentives as fundamental or important for considering an electric car purchase. Because of the differences in the socio-economic characteristics of consumers in each country, the effectiveness of government incentives may vary across Europe

The effects of dynamical substructure on Milky Way mass estimates from the high-velocity tail of the local stellar halo

We investigate the impact of dynamical streams and substructure on estimates of the local escape speed and total mass of Milky-Way-mass galaxies from modelling the high-velocity tail of local halo stars. We use a suite of high-resolution magnetohydrodynamical cosmological zoom-in simulations that resolve phase space substructure in local volumes around solar-like positions. We show that phase space structure varies significantly between positions in individual galaxies and across the suite. Substructure populates the high-velocity tail unevenly and leads to discrepancies in the mass estimates. We show that a combination of streams, sample noise, and truncation of the high-velocity tail below the escape speed leads to a distribution of mass estimates with a median that falls below the true value by ∼20 per cent ∼20 per cent ⁠, and a spread of a factor of 2 across the suite. Correcting for these biases, we derive a revised value for the Milky Way mass presented in Deason et al. of 1.29 +0.37 −0.47 × 10 12 M ⊙ 1.29−0.47+0.37×1012M⊙ ⁠

SAGIMA: An Easy-to-Use and Low Cost WEB-PACS System for an Optimal Access and Management of a Digital Angiography Database

Over several years, digital angiography studies from the Hemodynamic Unit of the Hospital Clínico Universitario (Valencia, Spain) have been stored in CD’s using first revisions of DICOM 3.0. In order to centralize the management and facilitate the access to these studies and reports, an easy to use and low cost WEB-PACS system that we have called SAGIMA has been developed in close collaboration between the BET Research Group of the Universitat Politècnica de València and the Cardiology Department of the Hospital Clínic

Efficient Emptiness Check for Timed B\"uchi Automata (Extended version)

The B\"uchi non-emptiness problem for timed automata refers to deciding if a given automaton has an infinite non-Zeno run satisfying the B\"uchi accepting condition. The standard solution to this problem involves adding an auxiliary clock to take care of the non-Zenoness. In this paper, it is shown that this simple transformation may sometimes result in an exponential blowup. A construction avoiding this blowup is proposed. It is also shown that in many cases, non-Zenoness can be ascertained without extra construction. An on-the-fly algorithm for the non-emptiness problem, using non-Zenoness construction only when required, is proposed. Experiments carried out with a prototype implementation of the algorithm are reported.Comment: Published in the Special Issue on Computer Aided Verification - CAV 2010; Formal Methods in System Design, 201

Operational forecasting of daily summer maximum and minimum temperatures in the Valencia Region

Extreme-temperature events have a great impact on human society. Thus, knowledge of summer temperatures can be very useful both for the general public and for organizations whose workers operate in the open. An accurate forecasting of summer maximum and minimum temperatures could help to predict heatwave conditions and permit the implementation of strategies aimed at minimizing the negative effects that high temperatures have on human health. The objective of this work is to evaluate the skill of the regional atmospheric and modelling system (RAMS) model in determining daily summer maximum and minimum temperatures in the Valencia Region. For this, we have used the real-time configuration of this model currently running at the Centro de Estudios Ambientales de Mediterráneo Foundation. This operational system is run twice a day, and both runs have a 3-day forecast range. To carry out the verification of the model in this work, the information generated by the system has been broken into individual simulation days for a specific daily run of the model. Moreover, we have analysed the summer forecast period from 1 June to 31 August for 2007, 2008, 2009 and 2010. The results indicate good agreement between observed and simulated maximum temperatures, with RMSE in general near 2 °C both for coastal and inland stations. For this parameter, the model shows a negative bias around −1.5 °C in the coast, while the opposite trend is observed inland. In addition, RAMS also shows good results in forecasting minimum temperatures for coastal locations, with bias lower than 1 °C and RMSE below 2 °C. However, the model presents some difficulties for this parameter inland, where bias higher than 3 °C and RMSE of about 4 °C have been found. Besides, there is little difference in both temperatures forecasted within the two daily RAMS cycles and that RAMS is very stable in maintaining the forecast performance at least for three forecast days

Simulating cosmological substructure in the solar neighbourhood

We explore the predictive power of cosmological, hydrodynamical simulations for stellar phase-space substructure and velocity correlations with the AURIGA simulations and AURIGAIA mock Gaia catalogues. We show that at the solar circle the AURIGA simulations commonly host phase-space structures in the stellar component that have constant orbital energies and arise from accreted subhaloes. These structures can persist for a few Gyr, even after coherent streams in position space have been erased. We also explore velocity two-point correlation functions and find this diagnostic is not deterministic for particular clustering patterns in phase space. Finally, we explore these structure diagnostics with the AURIGAIA catalogues and show that current catalogues have the ability to recover some structures in phase space but careful consideration is required to separate physical structures from numerical structures arising from catalogue generation methods

A functional connection between translation elongation and protein folding at the ribosome exit tunnel in Saccharomyces cerevisiae

Proteostasis needs to be tightly controlled to meet the cellular demand for correctly de novo folded proteins and to avoid protein aggregation. While a coupling between translation rate and co-translational folding, likely involving an interplay between the ribosome and its associated chaperones, clearly appears to exist, the underlying mechanisms and the contribution of ribosomal proteins remain to be explored. The ribosomal protein uL3 contains a long internal loop whose tip region is in close proximity to the ribosomal peptidyl transferase center. Intriguingly, the rpl3[W255C] allele, in which the residue making the closest contact to this catalytic site is mutated, affects diverse aspects of ribosome biogenesis and function. Here, we have uncovered, by performing a synthetic lethal screen with this allele, an unexpected link between translation and the folding of nascent proteins by the ribosome-associated Ssb-RAC chaperone system. Our results reveal that uL3 and Ssb-RAC cooperate to prevent 80S ribosomes from piling up within the 5′ region of mRNAs early on during translation elongation. Together, our study provides compelling in vivo evidence for a functional connection between peptide bond formation at the peptidyl transferase center and chaperone-assisted de novo folding of nascent polypeptides at the solvent-side of the peptide exit tunnel

Spectroscopic and Microscopic Characterization of Microbial Biofouling on Aircraft Fuel Tanks

Full text also available at: Europe PMC - https://europepmc.org/article/MED/38319653Avoiding microbial contamination and biofilm formation on the surfaces of aircraft fuel tanks is a major challenge in the aviation industry. The inevitable presence of water in fuel systems and nutrients provided by the fuel makes an ideal environment for bacteria, fungi, and yeast to grow. Understanding how microbes grow on different fuel tank materials is the first step to control biofilm formation in aviation fuel systems. In this study, biofilms of Pseudomonas putida, a model Gram-negative bacterium previously found in aircraft fuel tanks, were characterized on aluminum 7075-T6 surfaces, which is an alloy used by the aviation industry due to favorable properties including high strength and fatigue resistance. Scanning electron microscopy (SEM) coupled with energy-dispersive X-ray (EDX) showed that extracellular polymeric substances (EPS) produced by P. putida were important components of biofilms with a likely role in biofilm stability and adhesion to the surfaces. EDX analysis showed that the proportion of phosphorus with respect to nitrogen is higher in the EPS than in the bacterial cells. Additionally, different morphologies in biofilm formation were observed in the fuel phase compared to the water phase. Micro-Fourier transform infrared spectroscopy (micro-FTIR) analysis suggested that phosphoryl and carboxyl functional groups are fundamental for the irreversible attachment between the EPS of bacteria and the aluminum surface, by the formation of hydrogen bonds and inner-sphere complexes between the macromolecules and the aluminum surface. Based on the hypothesis that nucleic acids (particularly DNA) are an important component of EPS in P. putida biofilms, the impact of degrading extracellular DNA was tested. Treatment with the enzyme DNase I affected both water and fuel phase biofilms─with the cell structure disrupted in the aqueous phase, but cells remained attached to the aluminum coupons.InnovateUK and Airbus Operations Ltd., within the project “Fuel Architecture and Systems Technology (FAST)”, Project reference 113161 (TS/R008132/1). A.D.M. acknowledges funding from the UK Engineering and Physical Sciences Research Council (EPSRC) DTP scholarship (project reference: 2748843