Differences in Neuroticism Between Patients with Glaucoma Who Have Discontinued Visits to Ophthalmologists and Those Who Make Regular Visits: Implications for Adherence to Topical Glaucoma Medications

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Correlation map of striatal functional subdivisions and extrastriatal regions, in addition to that of within striatal subdivisions.

<p>Correlations in brighter color (yellow) represent higher ones in terms of magnitude than those in red.</p

Correlations between striatum and extrastriatal regions and intercorrelations among striatal subdivisions in dopamine D₁ receptor BP_ND.

<p>**P<0.01, *P<0.05. Correlations in red: intercorrelations among striatal subdivisions. Correlations in blue: correlations between striatal subdivisions and extrastriatal regions. R² values are presented for the correlations.</p

Definition of striatal functional subdivisions.

<p>Upper panel: MR images and regions of interest. Lower panel: parametric images corresponding to MR images in the upper panel.</p

Brain activations in High Cooperation condition and Low Cooperation condition relative to Control Cooperative condition.

<p>L, left; R, right; AI, anterior insula; DLPFC, dorsolateral prefrontal cortex; ACC, anterior cingulate cortex; OFC, orbitofrontal cortex; IPL, inferior parietal lobule. Coordinates and Z-score refer to the peak of each brain region.</p

The brain activation in High Cooperation minus Low Cooperation contrast.

<p>Significant activations observed in the right DLPFC (P<0.001, uncorrected for display use) (a) and left ACC (b). ACC, anterior cingulate cortex, DLPFC, dorsolateral prefrontal cortex.</p

The common brain activations in High minus Control Cooperation and Low minus Control Cooperation contrasts.

<p>Significant activations were observed in the bilateral AI, bilateral DLPFC, and OFC (P<0.001, uncorrected for display use). AI, anterior insula; DLPFC, dorsolateral prefrontal cortex; OFC, orbitofrontal cortex.</p

Brain activations in High minus Low Cooperation contrasts.

<p>L, left; R, right; DLPFC, dorsolateral prefrontal cortex; ACC, anterior cingulate cortex; MFG, middle frontal gyrus; IFG, inferior frontal gyrus. Coordinates and Z-score refer to the peak of each brain region.</p

Typical PET summation images of frames between 32–60 min after intravenous injection of [¹¹C]raclopride for baseline and drug challenge (6 mg of aripiprazole) studies.

<p>The sections are transaxial at the level of putamen.</p

Dose of aripiprazole and ranges of occupancy of dopamine D₂ receptors.

<p>(mean ± SD).</p