43 research outputs found

    An investigation into QoS provisioning in a DiffServ Network

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    The objective of this paper is to outline an investigation into the performance of various applications using both Expedited Forwarding (EF) and Assured Forwarding (AF) classification of traffic. Applications will be run on a generic testbed and then, through the use of open source and commercial packages, the traffic will be monitored and a performance evaluation will be carried out of the DiffServ network and the services it provides

    Garotas de loja, história social e teoria social [Shop Girls, Social History and Social Theory]

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    Shop workers, most of them women, have made up a significant proportion of Britain’s labour force since the 1850s but we still know relatively little about their history. This article argues that there has been a systematic neglect of one of the largest sectors of female employment by historians and investigates why this might be. It suggests that this neglect is connected to framings of work that have overlooked the service sector as a whole as well as to a continuing unease with the consumer society’s transformation of social life. One element of that transformation was the rise of new forms of aesthetic, emotional and sexualised labour. Certain kinds of ‘shop girls’ embodied these in spectacular fashion. As a result, they became enduring icons of mass consumption, simultaneously dismissed as passive cultural dupes or punished as powerful agents of cultural destruction. This article interweaves the social history of everyday shop workers with shifting representations of the ‘shop girl’, from Victorian music hall parodies, through modernist social theory, to the bizarre bombing of the Biba boutique in London by the Angry Brigade on May Day 1971. It concludes that progressive historians have much to gain by reclaiming these workers and the service economy that they helped create

    Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial

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    SummaryBackground Azithromycin has been proposed as a treatment for COVID-19 on the basis of its immunomodulatoryactions. We aimed to evaluate the safety and efficacy of azithromycin in patients admitted to hospital with COVID-19.Methods In this randomised, controlled, open-label, adaptive platform trial (Randomised Evaluation of COVID-19Therapy [RECOVERY]), several possible treatments were compared with usual care in patients admitted to hospitalwith COVID-19 in the UK. The trial is underway at 176 hospitals in the UK. Eligible and consenting patients wererandomly allocated to either usual standard of care alone or usual standard of care plus azithromycin 500 mg once perday by mouth or intravenously for 10 days or until discharge (or allocation to one of the other RECOVERY treatmentgroups). Patients were assigned via web-based simple (unstratified) randomisation with allocation concealment andwere twice as likely to be randomly assigned to usual care than to any of the active treatment groups. Participants andlocal study staff were not masked to the allocated treatment, but all others involved in the trial were masked to theoutcome data during the trial. The primary outcome was 28-day all-cause mortality, assessed in the intention-to-treatpopulation. The trial is registered with ISRCTN, 50189673, and ClinicalTrials.gov, NCT04381936.Findings Between April 7 and Nov 27, 2020, of 16 442 patients enrolled in the RECOVERY trial, 9433 (57%) wereeligible and 7763 were included in the assessment of azithromycin. The mean age of these study participants was65·3 years (SD 15·7) and approximately a third were women (2944 [38%] of 7763). 2582 patients were randomlyallocated to receive azithromycin and 5181 patients were randomly allocated to usual care alone. Overall,561 (22%) patients allocated to azithromycin and 1162 (22%) patients allocated to usual care died within 28 days(rate ratio 0·97, 95% CI 0·87–1·07; p=0·50). No significant difference was seen in duration of hospital stay (median10 days [IQR 5 to >28] vs 11 days [5 to >28]) or the proportion of patients discharged from hospital alive within 28 days(rate ratio 1·04, 95% CI 0·98–1·10; p=0·19). Among those not on invasive mechanical ventilation at baseline, nosignificant difference was seen in the proportion meeting the composite endpoint of invasive mechanical ventilationor death (risk ratio 0·95, 95% CI 0·87–1·03; p=0·24).Interpretation In patients admitted to hospital with COVID-19, azithromycin did not improve survival or otherprespecified clinical outcomes. Azithromycin use in patients admitted to hospital with COVID-19 should be restrictedto patients in whom there is a clear antimicrobial indication

    Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

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    Dimethyl fumarate (DMF) inhibits inflammasome-mediated inflammation and has been proposed as a treatment for patients hospitalised with COVID-19. This randomised, controlled, open-label platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]), is assessing multiple treatments in patients hospitalised for COVID-19 (NCT04381936, ISRCTN50189673). In this assessment of DMF performed at 27 UK hospitals, adults were randomly allocated (1:1) to either usual standard of care alone or usual standard of care plus DMF. The primary outcome was clinical status on day 5 measured on a seven-point ordinal scale. Secondary outcomes were time to sustained improvement in clinical status, time to discharge, day 5 peripheral blood oxygenation, day 5 C-reactive protein, and improvement in day 10 clinical status. Between 2 March 2021 and 18 November 2021, 713 patients were enroled in the DMF evaluation, of whom 356 were randomly allocated to receive usual care plus DMF, and 357 to usual care alone. 95% of patients received corticosteroids as part of routine care. There was no evidence of a beneficial effect of DMF on clinical status at day 5 (common odds ratio of unfavourable outcome 1.12; 95% CI 0.86-1.47; p = 0.40). There was no significant effect of DMF on any secondary outcome

    Comparison of Feature Classification Algorithm for Activity Recognition Based on Accelerometer and Heart Rate Data

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    This paper describes a project to compare two feature classification algorithms used in activity recognition in relation to accelerometer and heart rate data. Data was collected from six male and female subjects using a single tri-axial accelerometer and heart monitor attached to each subject’s dominant thigh. Subjects carried out eight activities and the data was labelled semi-automatically. Features (mean, standard deviation, energy, correlation and mean heart rate) were extracted from the data using a window of 256 (3.4 seconds) and an overlap of 50%. Two classifers, k-NN and J48, were evaluated for activity recognition with 10-fold validation with k-NN (k = 1) achieving a better overall score of 90.07%

    AUTONOMIC MANAGEMENT OF UBIQUITOUS COMPUTING ENVIRONMENTS

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    This technical paper provides an overview of IBM’s Autonomic Toolkit components and an introduction to my research into the development of autonomic services. The program should assess the effort and complexity involved in developing a simplified autonomic architecture on which a set of disparate services can be deployed and maintained autonomically. The advantages of such an architecture will then be compared against the ease of creating such autonomic environments. My research will show that autonomic computing does result in reduced complexity, increased productivity, graceful deployment and ease of management. However in researching the current state of the art in autonomic computing, I will explore some areas which require extensive further work in order to achieve the goals autonomic computing promises. The two main technologies that will be used to develop this architecture are IBM’s autonomic toolkit and Knopflerfish’s Open Service Gateway initiative (OSGi) framework. In this paper I will discuss these technologies and how they can be combined to produce an autonomic architecture

    An evaluation of QoS provisioning for UBR applications in a DiffServ Network

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    In this paper an understanding of the configuration and performance of a Differentiated Services (DS) network is presented. Strong emphasis is placed on the configuration of the quality of service (QoS) dynamics of expedited forwarding (EF) and assured forwarding (AF) per-hop behaviour (PHB) class types that are required to allow an Unspecified Bit Rate (UBR) application to function effectively - in particular, the configuration of the AF features that mark non-conformant packets with a lower drop priority DS Code Point (DSCP). The usability of these mechanisms is then evaluated in a real, testing environment. DS edge and core routers are configured in a testbed that has been created to emulate a multiple-domain network. Data was then collated from a diverse range of testing procedures and then analysed to allow the authors to draw their conclusions that increased their understanding how a DS network operates

    Management Experiences and Trends for Water Reuse Implementation in Northern California

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    In 2010, California fell nearly 300,000 acre-ft per year (AFY) short of its goal to recycle 1,000,000 AFY of municipal wastewater. Growth of recycled water in the 48 Northern California counties represented only 20% of the statewide increase in reuse between 2001 and 2009. To evaluate these trends and experiences, major drivers and challenges that influenced the implementation of recycled water programs in Northern California are presented based on a survey of 71 program managers conducted in 2010. Regulatory requirements limiting discharge, cited by 65% of respondents as a driver for program implementation, historically played an important role in motivating many water reuse programs in the region. More recently, pressures from limited water supplies and needs for system reliability are prevalent drivers. Almost half of respondents (49%) cited ecological protection or enhancement goals as drivers for implementation. However, water reuse for direct benefit of natural systems and wildlife habitat represents just 6–7% of total recycling in Northern California and few financial incentives exist for such projects. Economic challenges are the greatest barrier to successful project implementation. In particular, high costs of distribution systems (pipelines) are especially challenging, with $1 to 3 million/mile costs experienced. Negative perceptions of water reuse were cited by only 26% of respondents as major hindrances to implementation of surveyed programs
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