The scope of naturalism in British working-class drama, with particular reference to Joe Corrie, D.H. Lawrence and Sean O'Casey

The purpose of this dissertation is to define the scope of naturalism in British working-class drama with special reference to the plays of D.H. Lawrence, Sean O'Casey and Joe Corrie. To fulfill such a project, I undertook a personal assessment of the theory of naturalism and its practice in the theatre. For the purpose of being more comprehensive, I carried out a comparative study between working-class naturalism and that of the New Drama since the latter preceded the former. Having assessed and evaluated the theory of naturalism, in general, and its manifestation in the works of the new drama exponents and of the working-class dramatists, I defined and discussed the comparative aspects, as concepts, in the plays of three British playwrights. I have also tried to familiarize the reader with the features of the conversational analysis in the light of which I approached the issue of how similar to natural discourse dramatic dialogue may be. The study of the manifestation of naturalism in the plays of Lawrence, Corrie and O'Casey, which covers the last three chapters, is undertaken in the light of the scope of naturalism as I have previously defined it. In other words, an attempt is being made to question the validity of the naturalist theory as advocated by its exponents, and to prove the practicality of the angle from which I approached naturalism by examining certain plays. The study of the plays, therefore, allows me to define the extent to which one can refer to Lawrence, Corrie and O'Casey as naturalist dramatists and to question, if not to correct, some unfounded criticisms of naturalism in general and working-class naturalism in particular

Exploring the Phenomenon of Timelessness in Morocco: Insights from Paul Bowles and Other Travel Writers

This article aims to explore the phenomenon of timelessness in Morocco through the insights of renowned travel writers such as Paul Bowles. It will analyze the representations of Morocco in Western discourse, particularly in the context of Western Orientalism. Thanks to decolonization, deconstructionism, and Edward Said’s Orientalism, hitherto neglected travel writing has elicited academic responses from scholars who have recognized that travel writing is not simply an innocent and objective description of a traveler’s encounters in a foreign land. Instead, it is a genre that is inherently political, intertwined with projects of orientalism, colonialism, imperialism, and post-colonialism, and characterized by a hegemonic gaze directed towards the other, often marginalizing the voices of peripheral people. This research references books, notable authors, and Western explorers who commonly mention the unchanging quality of time in the Orient, particularly in Morocco. Additionally, the study will draw on the insights of Edward Said to explain why this timelessness was prevalent during that period

Exploring the Phenomenon of Timelessness in Morocco: Insights from Paul Bowles and Other Travel Writers

This article aims to explore the phenomenon of timelessness in Morocco through the insights of renowned travel writers such as Paul Bowles. It will analyze the representations of Morocco in Western discourse, particularly in the context of Western Orientalism. Thanks to decolonization, deconstructionism, and Edward Said’s Orientalism, hitherto neglected travel writing has elicited academic responses from scholars who have recognized that travel writing is not simply an innocent and objective description of a traveler’s encounters in a foreign land. Instead, it is a genre that is inherently political, intertwined with projects of orientalism, colonialism, imperialism, and post-colonialism, and characterized by a hegemonic gaze directed towards the other, often marginalizing the voices of peripheral people. This research references books, notable authors, and Western explorers who commonly mention the unchanging quality of time in the Orient, particularly in Morocco. Additionally, the study will draw on the insights of Edward Said to explain why this timelessness was prevalent during that period

Exploring the Phenomenon of Timelessness in Morocco: Insights from Paul Bowles and Other Travel Writers

This article aims to explore the phenomenon of timelessness in Morocco through the insights of renowned travel writers such as Paul Bowles. The semi-systematic method was used primarily due to the limited amount of research done on the topic of timelessness. It will analyze the representations of Morocco in Western discourse, particularly in the context of Western Orientalism. Thanks to decolonization, deconstructionism, and Edward Said’s Orientalism, hitherto neglected travel writing has elicited academic responses from scholars who have recognized that travel writing is not simply an innocent and objective description of a traveler’s encounters in a foreign land. Instead, it is a genre that is inherently political, intertwined with projects of orientalism, colonialism, imperialism, and post-colonialism, and characterized by a hegemonic gaze directed towards the other, often marginalizing the voices of peripheral people. This research references books, notable authors, and Western explorers who commonly mention the unchanging quality of time in the Orient, particularly in Morocco. Additionally, the study will draw on the insights of Edward Said to explain why this timelessness was prevalent in the 20th century

Enhancement of Early Osseointgration by Coating TiO2 Nanotubes with Annealed Fishbone(In Vivo Study)

New method was used to accelerate bone osseointegration, milled and annealed fishbone was used as coating layer on Ti-6Al-4V alloy after creating TiO2nanotube(TNTs) on it. Mechanical and thermal treatments were used to extract natural Hydroxyapatite (HAp) from fishbone.After milling, fish bones were heated at different temperatures. Annealed fish bones at 9000C had correspondence structure to that of standard one as X-ray diffraction (XRD) confirmed.  After creation TNTs on screws which were made from Ti-6Al-4V alloy, EPD was used to coat them with milled fishbone, annealed fishbone and commercial HAp. All screws were implanted inside the tibia of white New Zealand rabbits to evaluate the biocompatibility of modified alloys and to assess the clinical success of implants. Radiographic and histologic evaluations showed that implants with double surface modifications illustrate new bone formation around them. These results refer to the success of all surface modifications in this work , however the comparison between them illustrate superiority of coating by annealed fishbone over the other coating. During implantation interval from 4 to 12 weeks, screws with double surface modifications (creating TNTs and then coating with annealed fishbone) had highest removal torque (RTQ) values i.e. highest osseointegration acceleration rate. After 12 weeks of implantation, torque values for screws coated with commercial HAp are approximately equal to those values associated with screws coated with annealed fishbone. Keywords:Ossseointegration,Titaniumimplants,Hydroxyapatite, TiO2Nanotube,Fishbone

Characterization of a lung epithelium specific E-cadherin knock-out model:Implications for obstructive lung pathology

The airway epithelium regulates responses to aeroallergens, acting as a physical and immunological barrier. In asthma, epithelial barrier function and the expression of adherens junction protein E-cadherin is compromised, but it is unknown whether this is cause or consequence of the disease. We hypothesized that airway epithelial loss of E-cadherin is a critical step in the development of manifestations of asthma. We generated a transgenic mouse model with conditional loss of E-cadherin in lung epithelial cells at birth and onwards. We observed normal lung development at the time of birth in mice lacking E-cadherin in the lung epithelium. However, E-cadherin deficiency led to progressive epithelial damage in mice growing into adulthood, as evidenced by airway epithelial denudation, decreased zonula occludens (ZO)-1 expression, loss of ciliated cells, and enlarged alveolar spaces. In addition, spontaneous goblet cell metaplasia with mucus production was observed. These epithelial changes were accompanied by elevated levels of the epithelial-derived chemokine CCL17, infiltration of eosinophils and dendritic cells, and mucus production. In conclusion, loss of E-cadherin induces features in the lung reminiscent of those observed in asthma, indicating that the disruption of E-cadherin-mediated cell-cell contacts may play a key role in the development of asthma manifestations

Characterization of a lung epithelium specific E-cadherin knock-out model: Implications for obstructive lung pathology

The airway epithelium regulates responses to aeroallergens, acting as a physical and immunological barrier. In asthma, epithelial barrier function and the expression of adherens junction protein E-cadherin is compromised, but it is unknown whether this is cause or consequence of the disease. We hypothesized that airway epithelial loss of E-cadherin is a critical step in the development of manifestations of asthma. We generated a transgenic mouse model with conditional loss of E-cadherin in lung epithelial cells at birth and onwards. We observed normal lung development at the time of birth in mice lacking E-cadherin in the lung epithelium. However, E-cadherin deficiency led to progressive epithelial damage in mice growing into adulthood, as evidenced by airway epithelial denudation, decreased zonula occludens (ZO)-1 expression, loss of ciliated cells, and enlarged alveolar spaces. In addition, spontaneous goblet cell metaplasia with mucus production was observed. These epithelial changes were accompanied by elevated levels of the epithelial-derived chemokine CCL17, infiltration of eosinophils and dendritic cells, and mucus production. In conclusion, loss of E-cadherin induces features in the lung reminiscent of those observed in asthma, indicating that the disruption of E-cadherin-mediated cell-cell contacts may play a key role in the development of asthma manifestations

New Investigations in the Environment, History and Archaeology of the Iraqi Hilly Flanks: Shahrizor Survey Project 2009-2011

Recent palaeoenvironmental, historical, and archaeological investigations, primarily consisting of site reconnaissance, in the Shahrizor region within the province of Sulaymaniyah in Iraqi Kurdistan are bringing to light new information on the region’s social and socio-ecological development. This paper summarises two seasons of work by researchers from German, British, Dutch, and Iraqi-Kurdish institutions working in the survey region. Palaeoenvironmental data have determined that during the Pleistocene many terraces developed which came to be occupied by a number of the larger tell sites in the Holocene. In the sedimentary record, climatic and anthropogenic patterns are noticeable, and alluviation has affected the recovery of archaeological remains through site burial in places. Historical data show the Shahrizor shifting between periods of independence, either occupied by one regional state or several smaller entities, and periods that saw the plain’s incorporation within large empires, often in a border position. New archaeological investigations have provided insight into the importance of the region as a transit centre between Western Iran and northern and southern Mesopotamia, with clear material culture links recovered. Variations between periods’ settlement patterns and occupations are also beginning to emerge

Wound Healing Potential of Human Neonatal Mesenchymal Cells in an Animal Model of Hyperglycemia

Potential targeting of impaired wounds resulting from hyperglycemia using mesenchymal stem cells is a promising approach. We hypothesized that when administered to dermal wounds in hyperglycemic subjects, neonatal mesenchymal stem cells (MSCs) would be more effective than adult mesenchymal cells in accelerating healing. We examined the in vitro impact of various glucose conditions on proliferation and senescence of human umbilical cord perivascular cells (HUCPVCs) and adult bone marrow MSCs (hBM-MSCs). We also investigated the healing potential of both cells in dermal wounds of streptozotocin-induced NOD-scid-gamma (NSG) mice utilizing planimetry and histomorphometry. HUCPVCs showed higher proliferation under normal and hyperglycemic conditions and lower senescence under all conditions compared to hBM-MSCs. Wound closure was better in treated wounds compared to untreated wounds. Disease tolerance varied among mice which affected healing. HUCPVCs still holds a potential over adult MSCs for impaired wounds; yet more studies are needed to recognize their bona fide capacity.MAS

ENKI\u27S JOURNEY TO NIPPUR: THE JOURNEYS OF THE GODS

Abstract not availabl