La governance delle politiche in aree rurali: il "nodo" delle relazioni tra politiche a livello regionale. I casi della Regione Puglia e della Regione Sardegna

This report focuses on the governance of rural policies in two Italian regions: Apulia and Sardinia, located in the Mezzogiorno. The analysis highlights the administrative organisation of rural policies and the tools the regions put in place to coordinate and integrate the different policies. Despite the initial ambitions, Apulia failed in implementing effective tools of coordination and integration at the different tiers of programming and delivering policies. In the case of Sardinia, the experience of the Regional Programming Center was very positive , because it was capable to put strong efforts in coordinatind and integrating policies at the regional level. This might represent a sort of best practice for the other Italian Regions

La governance delle politiche in aree rurali: il "nodo" delle relazioni tra politiche a livello regionale. I casi della Regione Puglia e della Regione Sardegna

This report focuses on the governance of rural policies in two Italian regions: Apulia and Sardinia, located in the Mezzogiorno. The analysis highlights the administrative organisation of rural policies and the tools the regions put in place to coordinate and integrate the different policies. Despite the initial ambitions, Apulia failed in implementing effective tools of coordination and integration at the different tiers of programming and delivering policies. In the case of Sardinia, the experience of the Regional Programming Center was very positive , because it was capable to put strong efforts in coordinatind and integrating policies at the regional level. This might represent a sort of best practice for the other Italian Regions

Market, Policies and Local Governance as Drivers of Environmental Public Benefits: The Case of the Localised Processed Tomato in Northern Italy

This article explores the role of a specific Localised Agri-food System (LAFS) in the provision of Environmental and social benefits (ESBs) in densely cultivated, industrialised, and populated areas by analysing the core of the processing tomato supply chain of northern Italy (Parma and Piacenza). The research examines how the interplay of market drivers, public policies, and collective actions favoured farming, technological, and organisational innovations geared to support long-term economic growth and tackle, at the same time, environmental challenges. The tomato supply chain is characterised by a favourable convergence of attitudes, policies, and market conditions that over time allowed for fruitful interactions between private stakeholders and between the supply chain and public players. Decades of key stakeholders’ interconnections within the tomato supply chain led to a success story of economic growth and attention to a new balance between agro-industry and environment, for the benefit of producers/processors, consumers, and natural resources. Profitability strategies inevitably imply intensification of farming in order to maximise profit levels per hectare, however, the tomato supply chain found a collective motivation that could grant profitability and concurrently reward producers and processors for attention paid to safeguarding the environment—giving evidence that intensification does not necessarily conflict with requirements in support of sustainability

Current Clinical Psychopharmacology in Borderline Personality Disorder

Abstract: Background: Patients with Borderline Personality Disorder (BPD) manifest affective and behavioral symptoms causing personal distress, relationship difficulties, and reduced quality of life with global functioning impairment, mainly when the disease takes an unfavorable course. A substantial amount of healthcare costs is dedicated to addressing these issues. Many BPD patients receive medications, mostly those who do not respond to psychological interventions. Objective: Our aim was to assess the efficacy of the most used strategies of pharmacological interventions in BPD with a comprehensive overview of the field. Methods: We searched the PubMed database for papers focused on the most used psychotropic drugs for BPD. We included randomized controlled trials and open studies in adult patients with BPD, focusing on the efficacy and tolerability of single classes of drugs with respect to specific clinical presentations that may occur during the course of BPD. Results: Specific second-generation antipsychotics (SGAs) or serotonergic antidepressants can be effective for different core symptoms of BPD, mainly including mood symptoms, anxiety, and impulse dyscontrol. Some atypical antipsychotics can also be effective for psychotic and dissociative symptoms. Specific antiepileptics can be useful in some cases in treating different BPD symptoms, mainly including mood instability, impulsiveness, and anger. Conclusion: No medication is currently approved for BPD, and clinicians should carefully assess the benefits and risks of drug treatment. Further studies are needed to identify specific personalized treatment strategies, also considering the clinical heterogeneity and possible comorbidities of BPD

Evaluation support study on the impact of leader on balanced territorial development

LEADER promotes integrated rural Community-Led Local Development with key features of bottom-up and multi-sector approaches, local partnerships and place-based design and delivery, funded through the Common Agricultural Policy (Regulation (EU) No 1305/2013), under a common framework (Regulation (EU) No 1303/2013). This study evaluated LEADER across the EU in the 2014-2020 programming period. Methods included: literature review; major surveys of local action group (LAG) managers, and Managing Authorities; indicator analysis; and in-depth case studies of 36 LAGs and 14 Rural Development Programmes across 10 Member States. The study found LEADER was relevant and effective for local rural development, targeting and achieving economic development, strengthening social fabric and capacity and enhancing local governance, with good coherence alongside other policies. Most LAGs promoted social inclusion in a more limited way, and environmental goals via integration within socio-economic projects or awareness-raising. Tackling rural poverty was not a LEADER priority, but positive impacts were identified in a few case studies. Clear relationships and excellent support from Managing Authorities, also sufficient funds for animation, were crucial to LAG performance. Fuller implementation of LEADER key features positively influenced quality and scope of impacts. Strengthened network support at EU and national levels is recommended, also further simplification to ensure future obligations and conditions are proportionate, especially in cases of multi-funded CLLD where CAP (EARDF) and other ESI funds combine

Incidence, Risk Factors and Outcome of Pre-engraftment Gram-Negative Bacteremia after Allogeneic and Autologous Hematopoietic Stem Cell Transplantation: An Italian Prospective Multicenter Survey

Abstract BACKGROUND: Gram-negative bacteremia (GNB) is a major cause of illness and death after hematopoietic stem cell transplantation (HSCT), and updated epidemiological investigation is advisable. METHODS: We prospectively evaluated the epidemiology of pre-engraftment GNB in 1118 allogeneic HSCTs (allo-HSCTs) and 1625 autologous HSCTs (auto-HSCTs) among 54 transplant centers during 2014 (SIGNB-GITMO-AMCLI study). Using logistic regression methods. we identified risk factors for GNB and evaluated the impact of GNB on the 4-month overall-survival after transplant. RESULTS: The cumulative incidence of pre-engraftment GNB was 17.3% in allo-HSCT and 9% in auto-HSCT. Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa were the most common isolates. By multivariate analysis, variables associated with GNB were a diagnosis of acute leukemia, a transplant from a HLA-mismatched donor and from cord blood, older age, and duration of severe neutropenia in allo-HSCT, and a diagnosis of lymphoma, older age, and no antibacterial prophylaxis in auto-HSCT. A pretransplant infection by a resistant pathogen was significantly associated with an increased risk of posttransplant infection by the same microorganism in allo-HSCT. Colonization by resistant gram-negative bacteria was significantly associated with an increased rate of infection by the same pathogen in both transplant procedures. GNB was independently associated with increased mortality at 4 months both in allo-HSCT (hazard ratio, 2.13; 95% confidence interval, 1.45-3.13; P <.001) and auto-HSCT (2.43; 1.22-4.84; P = .01). CONCLUSIONS: Pre-engraftment GNB is an independent factor associated with increased mortality rate at 4 months after auto-HSCT and allo-HSCT. Previous infectious history and colonization monitoring represent major indicators of GNB. CLINICAL TRIALS REGISTRATION: NCT02088840