Primer details to sequence the coding sequence of AKT1.

<p>Primers in 5′ to 3′ direction.</p

Characteristics of 109 GBM tumor samples.

<p>Characteristics of 109 GBM tumor samples.</p

Example of one of the <i>GNAQ</i> mutations identified in blue naevi.

<p>The arrow indicates the location of the missense change p.Q209L (c.A627T).</p

PCR primers used for the mutational profiling.

<p>PCR primers used for the mutational profiling.</p

Sequence homology (at the protein level) and expression distribution in human tissues among Gq family genes.

<p>Sequence homology (at the protein level) and expression distribution in human tissues among Gq family genes.</p

Number of samples analyzed for each histological type and the number of mutations identified.

<p><b>(AML</b>: acute myeloid leukemia, <b>GIST</b>: Gastrointestinal Stromal Tumors; In addition, p-values of the Fisher's exact test, used to determine the tissue specificity for <i>GNAQ</i>^Q209 mutations in blue naevi, are listed.)</p