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    Effect of dietary cadmium on genome-wide 5mC levels in DNA of the hepatopancreas of <i>C</i>. <i>aspersus</i> adults.

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    <p>(<b>A</b>) The mean contents of 5mC in hepatopancreas DNA in each treatment group at each time point. (<b>B</b>) Estimated marginal means for dietary dose (as the main effect). (<b>C</b>) Estimated marginal means for time (as the main effect). Four snails were sampled for each treatment group at each time point (14, 28, and 56 days). Data are shown on a log<sub>10</sub> scale as mean (point) with one standard error (box) and one standard deviation (error bar). In Fig 2A the outliers (white circles) and the extremes (whiskers) are also given (if they exist). Marked boxes(*) indicate significant differences as compared to the reference group (Newman-Keuls test, ***—<i>p</i> < 0.001, **—<i>p</i> < 0.01, *—<i>p</i> < 0.05).</p
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